Literature for peptidase S01.198: mannan-binding lectin-associated serine peptidase 1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

(Topics flags: S Structure, M Mutation, K Knockout, I Inhibitor, R Splicing, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2023
  1. Sekine,H., Machida,T. and Fujita,T.
    Factor D
    Immunol Rev (2023) 313, 15-24. PubMed  Europe PubMed DOI  V
  2. 2022
  3. Bhagwat,S.R., Choudhary,K., Pandya,N., Sharma,S., Srivastava,S., Kumar,A. and Hajela,K.
    Identification of substrates of MBL Associated Serine Protease-1 (MASP-1) from human plasma using N-terminomics strategy
    Mol Immunol (2022) 151, 114-125. PubMed  Europe PubMed DOI
  4. Golomingi,M., Kohler,J., Jenny,L., Hardy,E.T., Dobo,J., Gal,P., Pal,G., Kiss,B., Lam,W.A. and Schroeder,V.
    Complement lectin pathway components MBL and MASP-1 promote haemostasis upon vessel injury in a microvascular bleeding model
    Front Immunol (2022) 13, 948190-948190. PubMed  Europe PubMed DOI  PMC  EPMC
  5. Hurler,L., Toonen,E.J.M., Kajdacsi,E., van Bree,B., Brandwijk,R.J.M.G., de Bruin,W., Lyons,P.A., Bergamaschi,L., Sinkovits,G., Cervenak,L., Wurzner,R. and Prohaszka,Z.
    Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs
    Front Immunol (2022) 13, 1039765-1039765. PubMed  Europe PubMed DOI  PMC  EPMC
  6. Nagy,Z.A., Heja,D., Bencze,D., Kiss,B., Boros,E., Szakacs,D., Fodor,K., Wilmanns,M., Kocsis,A., Dobo,J., Gal,P., Harmat,V. and Pal,G.
    Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation
    J Biol Chem (2022) 298, 101985-101985. PubMed  Europe PubMed DOI  PMC  EPMC
  7. 2021
  8. Choudhary,K., Patel,P.K., Are,V.N., Makde,R.D. and Hajela,K.
    Mannose-binding lectin-associated serine protease-1 cleaves plasminogen and plasma fibronectin: prefers plasminogen over known fibrinogen substrate
    Blood Coagul Fibrinolysis (2021) 32, 504-512. PubMed  Europe PubMed DOI
  9. Pihl,R., Jensen,R.K., Poulsen,E.C., Jensen,L., Hansen,A.G., Thogersen,I.B., Dobo,J., Gal,P., Andersen,G.R., Enghild,J.J. and Thiel,S.
    ITIH4 acts as a protease inhibitor by a novel inhibitory mechanism
    Sci Adv (2021) 7 PubMed  Europe PubMed DOI  PMC  EPMC
  10. Rosbjerg,A., Wurzner,R., Garred,P. and Skjoedt,M.O.
    MASP-1 and MASP-3 Bind Directly to Aspergillus fumigatus and Promote Complement Activation and Phagocytosis
    J Innate Immun (2021) , 1-14. PubMed  Europe PubMed DOI
  11. 2020
  12. Cedzynski,M. and Swierzko,A.S.
    Components of the Lectin Pathway of Complement in Haematologic Malignancies
    Cancers (Basel) (2020) 12 PubMed  Europe PubMed DOI
  13. Fuentes-Prior,P.
    Priming of SARS-CoV-2 S protein by several membrane-bound serine proteinases could explain enhanced viral infectivity and systemic COVID-19 infection
    J Biol Chem (2020) PubMed  Europe PubMed DOI  V
  14. Gajek,G., Swierzko,A.S. and Cedzynski,M.
    Association of Polymorphisms of MASP1/3, COLEC10, and COLEC11 Genes with 3MC Syndrome
    Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI
  15. 2019
  16. Debreczeni,M.L., Nemeth,Z., Kajdacsi,E., Schwaner,E., Mako,V., Masszi,A., Doleschall,Z., Rigo,J., Walter,F.R., Deli,M.A., Pal,G., Dobo,J., Gal,P. and Cervenak,L.
    MASP-1 Increases endothelial permeability
    Front Immunol (2019) 10, 991-991. PubMed  Europe PubMed DOI  PMC  EPMC
  17. 2018
  18. Parej,K., Kocsis,A., Enyingi,C., Dani,R., Oroszlan,G., Beinrohr,L., Dobo,J., Zavodszky,P., Pal,G. and Gal,P.
    Cutting edge: a new player in the alternative complement pathway, MASP-1 is essential for LPS-induced, but not for Zymosan-induced, alternative pathway activation
    J Immunol (2018) 200, 2247-2252. PubMed  Europe PubMed DOI
  19. 2016
  20. Banda,N.K., Acharya,S., Scheinman,R.I., Mehta,G., Coulombe,M., Takahashi,M., Sekine,H., Thiel,S., Fujita,T. and Holers,V.M.
    Mannan-binding lectin-associated serine protease 1/3 cleavage of pro-factor D into factor D in vivo and attenuation of collagen antibody-induced arthritis through their targeted inhibition by RNA interference-mediated gene silencing
    J Immunol (2016) 197, 3680-3694. PubMed  Europe PubMed DOI
  21. Dobo,J., Pal,G., Cervenak,L. and Gal,P.
    The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond
    Immunol Rev (2016) 274, 98-111. PubMed  Europe PubMed DOI
  22. 2015
  23. Jenny,L., Dobo,J., Gal,P. and Schroeder,V.
    MASP-1 of the complement system promotes clotting via prothrombin activation
    Mol Immunol (2015) 65, 398-405. PubMed  Europe PubMed DOI
  24. Jenny,L., Dobo,J., Gal,P. and Schroeder,V.
    MASP-1 induced clotting - the first model of prothrombin activation by MASP-1
    PLoS ONE (2015) 10, e0144633-e0144633. PubMed  Europe PubMed DOI  PMC  EPMC
  25. 2014
  26. Rosbjerg,A., Munthe-Fog,L., Garred,P. and Skjoedt,M.O.
    Heterocomplex formation between MBL/ficolin/CL-11-associated serine protease-1 and -3 and MBL/ficolin/CL-11-associated protein-1
    J Immunol (2014) 192, 4352-4360. PubMed  Europe PubMed DOI
  27. 2013
  28. Degn,S.E., Thiel,S. and Jensenius,J.C.
    Recombinant expression of the autocatalytic complement protease MASP-1 is crucially dependent on co-expression with its inhibitor, C1 inhibitor
    Protein Expr Purif (2013) 88, 173-182. PubMed  Europe PubMed DOI  E
  29. 2012
  30. Heja,D., Harmat,V., Fodor,K., Wilmanns,M., Dobo,J., Kekesi,K.A., Zavodszky,P., Gal,P. and Pal,G.
    Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and -2 are essential for lectin pathway activation and reveal structural plasticity of MASP-2
    J Biol Chem (2012) 287, 20290-20300. PubMed  Europe PubMed DOI
  31. La Bonte,L.R., Pavlov,V.I., Tan,Y.S., Takahashi,K., Takahashi,M., Banda,N.K., Zou,C., Fujita,T. and Stahl,G.L.
    Mannose-binding lectin-associated serine protease-1 is a significant contributor to coagulation in a murine model of occlusive thrombosis
    J Immunol (2012) 188, 885-891. PubMed  Europe PubMed DOI
  32. Schwaeble,W.J., Lynch,N.J., Gal,P. and Zavodszky,P.
    Mannan-binding lectin-associated serine proteases
    [ISSN:978-0-12-407742-3] (2012) 3, 2857-2863. DOI
  33. Yongqing,T., Drentin,N., Duncan,R.C., Wijeyewickrema,L.C. and Pike,R.N.
    Mannose-binding lectin serine proteases and associated proteins of the lectin pathway of complement: two genes, five proteins and many functions?
    Biochim Biophys Acta (2012) 1824, 253-262. PubMed  Europe PubMed DOI  V  R
  34. 2011
  35. Banda,N.K., Takahashi,M., Takahashi,K., Stahl,G.L., Hyatt,S., Glogowska,M., Wiles,T.A., Endo,Y., Fujita,T., Michael Holers,V. and Arend,W.P.
    Mechanisms of mannose-binding lectin-associated serine proteases-1/3 activation of the alternative pathway of complement
    Mol Immunol (2011) 49, 281-289. PubMed  Europe PubMed DOI
  36. Dobo,J., Major,B., Kekesi,K.A., Szabo,I., Megyeri,M., Hajela,K., Juhasz,G., Zavodszky,P. and Gal,P.
    Cleavage of kininogen and subsequent bradykinin release by the complement component: mannose-binding lectin-associated serine protease (MASP)-1
    PLoS ONE (2011) 6, e20036-e20036. PubMed  Europe PubMed DOI  PMC  EPMC
  37. Gingras,A.R., Girija,U.V., Keeble,A.H., Panchal,R., Mitchell,D.A., Moody,P.C. and Wallis,R.
    Structural basis of mannan-binding lectin recognition by its associated serine protease MASP-1: implications for complement activation
    Structure (2011) 19, 1635-1643. PubMed  Europe PubMed DOI  S
  38. Takahashi,K., Chang,W.C., Takahashi,M., Pavlov,V., Ishida,Y., La Bonte,L., Shi,L., Fujita,T., Stahl,G.L. and Van Cott,E.M.
    Mannose-binding lectin and its associated proteases (MASPs) mediate coagulation and its deficiency is a risk factor in developing complications from infection, including disseminated intravascular coagulation
    Immunobiology (2011) 216, 96-102. PubMed  Europe PubMed DOI
  39. 2010
  40. Degn,S.E., Jensen,L., Gal,P., Dobo,J., Holmvad,S.H., Jensenius,J.C. and Thiel,S.
    Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system
    J Immunol Methods (2010) 361, 37-50. PubMed  Europe PubMed DOI  R
  41. Gulla,K.C., Gupta,K., Krarup,A., Gal,P., Schwaeble,W.J., Sim,R.B., O'Connor,C.D. and Hajela,K.
    Activation of mannan-binding lectin-associated serine proteases leads to generation of a fibrin clot
    Immunology (2010) 129, 482-495. PubMed  Europe PubMed DOI
  42. Kocsis,A., Kekesi,K.A., Szasz,R., Vegh,B.M., Balczer,J., Dobo,J., Zavodszky,P., Gal,P. and Pal,G.
    Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation
    J Immunol (2010) 185, 4169-4178. PubMed  Europe PubMed DOI  I
  43. Skjoedt,M.O., Hummelshoj,T., Palarasah,Y., Honore,C., Koch,C., Skjodt,K. and Garred,P.
    A novel mannose-binding lectin/ficolin-associated protein is highly expressed in heart and skeletal muscle tissues and inhibits complement activation
    J Biol Chem (2010) 285, 8234-8243. PubMed  Europe PubMed DOI  PMC  EPMC
  44. Takahashi,M., Ishida,Y., Iwaki,D., Kanno,K., Suzuki,T., Endo,Y., Homma,Y. and Fujita,T.
    Essential role of mannose-binding lectin-associated serine protease-1 in activation of the complement factor D
    J Exp Med (2010) 207, 29-37. PubMed  Europe PubMed DOI  K
  45. 2009
  46. Degn,S.E., Hansen,A.G., Steffensen,R., Jacobsen,C., Jensenius,J.C. and Thiel,S.
    MAp44, a human protein associated with pattern recognition molecules of the complement system and regulating the lectin pathway of complement activation
    J Immunol (2009) 183, 7371-7378. PubMed  Europe PubMed DOI
  47. Dobo,J., Harmat,V., Beinrohr,L., Sebestyen,E., Zavodszky,P. and Gal,P.
    MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity
    J Immunol (2009) 183, 1207-1214. PubMed  Europe PubMed DOI  S
  48. Gal,P., Dobo,J., Zavodszky,P. and Sim,R.B.
    Early complement proteases: C1r, C1s and MASPs. A structural insight into activation and functions
    Mol Immunol (2009) 46, 2745-2752. PubMed  Europe PubMed DOI  V
  49. Megyeri,M., Mako,V., Beinrohr,L., Doleschall,Z., Prohaszka,Z., Cervenak,L., Zavodszky,P. and Gal,P.
    Complement protease MASP-1 activates human endothelial cells: PAR4 activation is a link between complement and endothelial function
    J Immunol (2009) 183, 3409-3416. PubMed  Europe PubMed DOI
  50. 2008
  51. Dobo,J., Harmat,V., Sebestyen,E., Beinrohr,L., Zavodszky,P. and Gal,P.
    Purification, crystallization and preliminary X-ray analysis of human mannose-binding lectin-associated serine protease-1 (MASP-1) catalytic region
    Acta Crystallograph Sect F Struct Biol Cryst Commun (2008) 64, 781-784. PubMed  Europe PubMed DOI  PMC  EPMC
  52. Krarup,A., Gulla,K.C., Gal,P., Hajela,K. and Sim,R.B.
    The action of MBL-associated serine protease 1 (MASP1) on factor XIII and fibrinogen
    Biochim Biophys Acta (2008) 1784, 1294-1300. PubMed  Europe PubMed DOI
  53. Takahashi,M., Iwaki,D., Kanno,K., Ishida,Y., Xiong,J., Matsushita,M., Endo,Y., Miura,S., Ishii,N., Sugamura,K. and Fujita,T.
    Mannose-Binding Lectin (MBL)-Associated Serine Protease (MASP)-1 Contributes to Activation of the Lectin Complement Pathway
    J Immunol (2008) 180, 6132-6138. PubMed  Europe PubMed  K
  54. Teillet,F., Gaboriaud,C., Lacroix,M., Martin,L., Arlaud,G.J. and Thielens,N.M.
    Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins
    J Biol Chem (2008) 283, 25715-25724. PubMed  Europe PubMed DOI  S
  55. 2007
  56. Gal,P., Barna,L., Kocsis,A. and Zavodszky,P.
    Serine proteases of the classical and lectin pathways: similarities and differences
    Immunobiology (2007) 212, 267-277. PubMed  Europe PubMed DOI  V
  57. Kang,H.J., Lee,S.M., Lee,H.H., Kim,J.Y., Lee,B.C., Yum,J.S., Moon,H.M. and Lee,B.L.
    Mannose-binding lectin without the aid of its associated serine proteases alters lipopolysaccharide-mediated cytokine/chemokine secretion from human endothelial cells
    Immunology (2007) 122, 335-342. PubMed  Europe PubMed DOI  PMC  EPMC
  58. Moller-Kristensen,M., Thiel,S., Sjoholm,A., Matsushita,M. and Jensenius,J.C.
    Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway
    Int Immunol (2007) 19, 141-149. PubMed  Europe PubMed DOI
  59. Takahashi,M., Mori,S., Shigeta,S. and Fujita,T.
    Role of MBL-associated serine protease (MASP) on activation of the lectin complement pathway
    Adv Exp Med Biol (2007) 598, 93-104. PubMed  Europe PubMed DOI  V
  60. Weiss,G., Madsen,H.O. and Garred,P.
    A novel mannose-binding lectin-associated serine protease 1/3 gene variant
    Scand J Immunol (2007) 65, 430-434. PubMed  Europe PubMed DOI  M
  61. 2006
  62. Selander,B., Martensson,U., Weintraub,A., Holmstrom,E., Matsushita,M., Thiel,S., Jensenius,J.C., Truedsson,L. and Sjoholm,A.G.
    Mannan-binding lectin activates C3 and the alternative complement pathway without involvement of C2
    J Clin Invest (2006) 116, 1425-1434. PubMed  Europe PubMed DOI  PMC  EPMC
  63. 2005
  64. [YEAR:15-4-2005]Lynch,N.J., Khan,S.U., Stover,C.M., Sandrini,S.M., Marston,D., Presanis,J.S. and Schwaeble,W.J.
    Composition of the lectin pathway of complement in Gallus gallus: absence of mannan-binding lectin-associated serine protease-1 in birds
    J Immunol (15-4-2005) 174, 4998-5006. PubMed  Europe PubMed
  65. Song,L., Takamune,K., Sugawara,Y. and Fujii,T.
    cDNA cloning of a mannose-binding lectin-associated serine protease (MASP) gene from hagfish (Eptatretus burgeri)
    Zoolog Sci (2005) 22, 897-904. PubMed  Europe PubMed DOI
  66. 2004
  67. [YEAR:18-6-2004]Chen,C.B. and Wallis,R.
    Two mechanisms for mannose-binding protein modulation of the activity of its associated serine proteases
    J Biol Chem (18-6-2004) 279, 26058-26065. PubMed  Europe PubMed DOI
  68. Presanis,J.S., Hajela,K., Ambrus,G., Gal,P. and Sim,R.B.
    Differential substrate and inhibitor profiles for human MASP-1 and MASP-2
    Mol Immunol (2004) 40, 921-929. PubMed  Europe PubMed DOI
  69. Schwaeble,W.J., Stover,C. and Reid,K.B.M.
    Mannan-binding lectin-associated serine proteases
    [ISSN:0-12-079610-4] (2004) 2, 1623-1627.  V
  70. Wallis,R., Shaw,J.M., Uitdehaag,J., Chen,C.B., Torgersen,D. and Drickamer,K.
    Localization of the serine protease-binding sites in the collagen-like domain of mannose-binding protein: indirect effects of naturally occurring mutations on protease binding and activation
    J Biol Chem (2004) 279, 14065-14073. PubMed  Europe PubMed DOI
  71. 2003
  72. [YEAR:1-2-2003]Ambrus,G., Gal,P., Kojima,M., Szilagyi,K., Balczer,J., Antal,J., Graf,L., Laich,A., Moffatt,B.E., Schwaeble,W., Sim,R.B. and Zavodszky,P.
    Natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and -2: a study on recombinant catalytic fragments
    J Immunol (1-2-2003) 170, 1374-1382. PubMed  Europe PubMed
  73. [YEAR:1-5-2003]Endo,Y., Nonaka,M., Saiga,H., Kakinuma,Y., Matsushita,A., Takahashi,M., Matsushita,M. and Fujita,T.
    Origin of mannose-binding lectin-associated serine protease (MASP)-1 and MASP-3 involved in the lectin complement pathway traced back to the invertebrate, amphioxus
    J Immunol (1-5-2003) 170, 4701-4707. PubMed  Europe PubMed
  74. Presanis,J.S., Kojima,M. and Sim,R.B.
    Biochemistry and genetics of mannan-binding lectin (MBL)
    Biochem Soc Trans (2003) 31, 748-752. PubMed  Europe PubMed DOI
  75. 2002
  76. [YEAR:15-11-2002]Cseh,S., Vera,L., Matsushita,M., Fujita,T., Arlaud,G.J. and Thielens,N.M.
    Characterization of the interaction between L-ficolin/p35 and mannan-binding lectin-associated serine proteases-1 and -2
    J Immunol (15-11-2002) 169, 5735-5743. PubMed  Europe PubMed
  77. Endo,Y., Takahashi,M., Kuraya,M., Matsushita,M., Stover,C.M., Schwaeble,W.J. and Fujita,T.
    Functional characterization of human mannose-binding lectin-associated serine protease (MASP)-1/3 and MASP-2 promoters, and comparison with the C1s promoter
    Int Immunol (2002) 14, 1193-1201. PubMed  Europe PubMed
  78. Fujita,T.
    Evolution of the lectin-complement pathway and its role in innate immunity
    Nat Rev Immunol (2002) 2, 346-353. PubMed  Europe PubMed DOI
  79. Hajela,K., Kojima,M., Ambrus,G., Wong,K.H., Moffatt,B.E., Ferluga,J., Hajela,S., Gal,P. and Sim,R.B.
    The biological functions of MBL-associated serine proteases (MASPs)
    Immunobiology (2002) 205, 467-475. PubMed  Europe PubMed
  80. Nonaka,M. and Miyazawa,S.
    Evolution of the initiating enzymes of the complement system
    Genome Biol (2002) 3, REVIEWS1001-REVIEWS1001. PubMed  Europe PubMed  PMC  EPMC
  81. Schwaeble,W., Dahl,M.R., Thiel,S., Stover,C. and Jensenius,J.C.
    The mannan-binding lectin-associated serine proteases (MASPs) and MAp19: four components of the lectin pathway activation complex encoded by two genes
    Immunobiology (2002) 205, 455-466. PubMed  Europe PubMed DOI  R
  82. 2001
  83. [YEAR:13-7-2001]Chen,C.B. and Wallis,R.
    Stoichiometry of complexes between mannose-binding protein and its associated serine proteases. Defining functional units for complement activation
    J Biol Chem (13-7-2001) 276, 25894-25902. PubMed  Europe PubMed DOI
  84. [YEAR:2-11-2001]Rossi,V., Cseh,S., Bally,I., Thielens,N.M., Jensenius,J.C. and Arlaud,G.J.
    Substrate specificities of recombinant mannan-binding lectin-associated serine proteases-1 and-2
    J Biol Chem (2-11-2001) 276, 40880-40887. PubMed  Europe PubMed DOI
  85. [YEAR:15-4-2001]Thielens,N.M., Cseh,S., Thiel,S., Vorup-Jensen,T., Rossi,V., Jensenius,J.C. and Arlaud,G.J.
    Interaction properties of human mannan-binding lectin (MBL)-associated serine proteases-1 and -2, MBL-associated protein 19, and MBL
    J Immunol (15-4-2001) 166, 5068-5077. PubMed  Europe PubMed
  86. 2000
  87. [YEAR:1-3-2000]Matsushita,M., Endo,Y. and Fujita,T.
    Cutting edge: Complement-activating complex of ficolin and mannose-binding lectin-associated serine protease
    J Immunol (1-3-2000) 164, 2281-2284. PubMed  Europe PubMed
  88. [YEAR:1-9-2000]Matsushita,M., Thiel,S., Jensenius,J.C., Terai,I. and Fujita,T.
    Proteolytic activities of two types of mannose-binding lectin-associated serine protease
    J Immunol (1-9-2000) 165, 2637-2642. PubMed  Europe PubMed
  89. Sim,R.B. and Laich,A.
    Serine proteases of the complement system
    Biochem Soc Trans (2000) 28, 545-550. PubMed  Europe PubMed
  90. [YEAR:6-10-2000]Wallis,R. and Dodd,R.B.
    Interaction of mannose-binding protein with associated serine proteases: effects of naturally occurring mutations
    J Biol Chem (6-10-2000) 275, 30962-30969. PubMed  Europe PubMed DOI
  91. 1999
  92. Takayama,Y., Takada,F., Nowatari,M., Kawakami,M. and Matsu-ura,N.
    Gene structure of the P100 serine-protease component of the human Ra-reactive factor
    Mol Immunol (1999) 36, 505-514. PubMed  Europe PubMed DOI
  93. Wong,N.K., Kojima,M., Dobo,J., Ambrus,G. and Sim,R.B.
    Activities of the MBL-associated serine proteases (MASPs) and their regulation by natural inhibitors
    Mol Immunol (1999) 36, 853-861. PubMed  Europe PubMed DOI
  94. 1998
  95. Matsushita,M., Endo,Y. and Fujita,T.
    MASP1 (MBL-associated serine protease 1)
    Immunobiology (1998) 199, 340-347. PubMed  Europe PubMed DOI
  96. Matsushita,M., Endo,Y., Nonaka,M. and Fujita,T.
    Complement-related serine proteases in tunicates and vertebrates
    Curr Opin Immunol (1998) 10, 29-35. PubMed  Europe PubMed DOI
  97. 1997
  98. Ji,X., Azumi,K., Sasaki,M. and Nonaka,M.
    Ancient origin of the complement lectin pathway revealed by molecular cloning of mannan binding protein-associated serine protease from a urochordate, the Japanese ascidian, Halocynthia roretzi
    Proc Natl Acad Sci U S A (1997) 94, 6340-6345. PubMed  Europe PubMed DOI  PMC  EPMC
  99. Knittel,T., Fellmer,P., Neubauer,K., Kawakami,M., Grundmann,A. and Ramadori,G.
    The complement-activating protease P100 is expressed by hepatocytes and is induced by IL-6 in vitro and during the acute phase reaction in vivo
    Lab Invest (1997) 77, 221-230. PubMed  Europe PubMed
  100. 1996
  101. Endo,Y., Sato,T., Matsushita,M. and Fujita,T.
    Exon structure of the gene encoding the human mannose-binding protein-associated serine protease light chain: Comparison with complement C1r and C1s genes
    Int Immunol (1996) 8, 1355-1358. PubMed  Europe PubMed
  102. Tan,S.M., Chung,M.C., Kon,O.L., Thiel,S., Lee,S.H. and Lu,J.
    Improvements on the purification of mannan-binding lectin and demonstration of its Ca(2+)-independent association with a C1s-like serine protease
    Biochem J (1996) 319, 329-332. PubMed  Europe PubMed  PMC  EPMC
  103. 1995
  104. Ogata,R.T., Low,P.J. and Kawakami,M.
    Substrate specificities of the protease of mouse serum Ra-reactive factor
    J Immunol (1995) 154, 2351-2357. PubMed  Europe PubMed
  105. Terai,I., Kobayashi,K., Matsushita,M., Fujita,T. and Matsuno,K.
    alpha2-Macroglobulin binds to and inhibits mannose-binding protein-associated serine protease
    Int Immunol (1995) 7, 1579-1584. PubMed  Europe PubMed
  106. 1994
  107. Sato,T., Endo,Y., Matsushita,M. and Fujita,T.
    Molecular characterization of a novel serine protease involved in activation of the complement system by mannose-binding protein
    Int Immunol (1994) 6, 665-669. PubMed  Europe PubMed
  108. Takayama,Y., Takada,F., Takahashi,A. and Kawakami,M.
    A 100-kDa protein in the C4-activating component of Ra-reactive factor is a new serine protease having module organization similar to C1r and C1s
    J Immunol (1994) 152, 2308-2316. PubMed  Europe PubMed
  109. 1993
  110. Ji,Y.H., Fujita,T., Hatsuse,H., Takahashi,A., Matsushita,M. and Kawakami,M.
    Activation of the C4 and C2 components of complement by a proteinase in serum bactericidal factor, Ra reactive factor
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