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Literature for peptidase S01.194: complement component C2a

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, I Inhibitor, R Splicing, E Expression, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. Ning,G., Huang,Y.L., Zhen,L.M., Xu,W.X., Li,X.J., Wu,L.N., Liu,Y., Xie,C. and Peng,L.
    Prognostic Value of Complement Component 2 and Its Correlation with Immune Infiltrates in Hepatocellular Carcinoma
    Biomed Res Int2020, 3765937-3765937. PubMed  Europe PubMed DOI
    2. 2019
  2. Peng,M., Li,Z., Niu,D., Liu,X., Dong,Z. and Li,J.
    Complement factor B/C2 in molluscs regulates agglutination and illuminates evolution of the Bf/C2 family
    FASEB J33, 13323-13333. PubMed  Europe PubMed DOI
    3. 2014
  3. Norton,A.W., Martini,P.G., Cook,L.C., Alderucci,S., Lundberg,D.M., Fish,S.M., Bedard,C., Gill,J., Tzianabos,A.O. and Concino,M.F.
    Expression and purification methods for the production of recombinant human complement component c2
    Methods Mol Biol1100, 61-74. PubMed  Europe PubMed DOI  E
    4. 2012
  4. Forneris,F., Wu,J. and Gros,P.
    The modular serine proteases of the complement cascade
    Curr Opin Struct Biol22, 333-341. PubMed  Europe PubMed DOI  V
  5. Kerr,M.A.
    Complement component C2: the classical and lectin pathway C3/C5 convertases
    [ISSN:978-0-12-407742-3]3, 2863-2868. DOI
    6. 2011
  6. Laursen,N.S., Andersen,K.R., Braren,I., Spillner,E., Sottrup-Jensen,L. and Andersen,G.R.
    Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex
    EMBO J30, 606-616. PubMed  Europe PubMed DOI
    7. 2010
  7. Martini,P.G., Cook,L.C., Alderucci,S., Norton,A.W., Lundberg,D.M., Fish,S.M., Langsetmo,K., Jonsson,G., Lood,C., Gullstrand,B., Zaleski,K.J., Savioli,N., Lottherand,J., Bedard,C., Gill,J., Concino,M.F., Heartlein,M.W., Truedsson,L., Powell,J.L. and Tzianabos,A.O.
    Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases
    BMC Immunol11, 43-43. PubMed  Europe PubMed DOI  E  U
    8. 2009
  8. Halili,M.A., Ruiz-Gomez,G., Le,G.T., Abbenante,G. and Fairlie,D.P.
    Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activation
    Biochemistry48, 8466-8472. PubMed  Europe PubMed DOI
  9. Krishnan,V., Xu,Y., Macon,K., Volanakis,J.E. and Narayana,S.V.
    The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation
    Acta Crystallogr D Biol Crystallogr65, 266-274. PubMed  Europe PubMed DOI
    10. 2007
  10. Krishnan,V., Xu,Y., Macon,K., Volanakis,J.E. and Narayana,S.V.
    The crystal structure of C2a, the catalytic fragment of classical pathway C3 and C5 convertase of human complement
    J Mol Biol367, 224-233. PubMed  Europe PubMed DOI  S
  11. Wallis,R., Dodds,A.W., Mitchell,D.A., Sim,R.B., Reid,K.B. and Schwaeble,W.J.
    Molecular interactions between MASP-2, C4, and C2 and their activation fragments leading to complement activation via the lectin pathway
    J Biol Chem282, 7844-7851. PubMed  Europe PubMed DOI
    12. 2006
  12. Milder,F.J., Raaijmakers,H.C., Vandeputte,M.D., Schouten,A., Huizinga,E.G., Romijn,R.A., Hemrika,W., Roos,A., Daha,M.R. and Gros,P.
    Structure of complement component C2a: implications for convertase formation and substrate binding
    Structure14, 1587-1597. PubMed  Europe PubMed DOI  S
  13. Selander,B., Martensson,U., Weintraub,A., Holmstrom,E., Matsushita,M., Thiel,S., Jensenius,J.C., Truedsson,L. and Sjoholm,A.G.
    Mannan-binding lectin activates C3 and the alternative complement pathway without involvement of C2
    J Clin Invest116, 1425-1434. PubMed  Europe PubMed DOI
  14. Springer,T.A.
    Complement and the multifaceted functions of VWA and integrin I domains
    Structure14, 1611-1616. PubMed  Europe PubMed DOI
    15. 2004
  15. Kerr,M.A.
    Complement component C2: the classical and lectin pathway C3/C5 convertases
    [ISSN:0-12-079610-4]2, 1627-1632.  V
    16. 2000
  16. [YEAR:24-3-2000]Inal,J.M. and Sim,R.B.
    A Schistosoma protein, Sh-TOR, is a novel inhibitor of complement which binds human C2
    FEBS Lett470, 131-134. PubMed  Europe PubMed DOI
  17. [YEAR:17-1-2000]Jing,H., Xu,Y.Y., Carson,M., Moore,D., Macon,K.J., Volanakis,J.E. and Narayana,S.V.L.
    New structural motifs on the chymotrypsin fold and their potential roles in complement factor B
    EMBO J19, 164-173. PubMed  Europe PubMed DOI  S
  18. Sim,R.B. and Laich,A.
    Serine proteases of the complement system
    Biochem Soc Trans28, 545-550. PubMed  Europe PubMed
    19. 1995
  19. [YEAR:10-2-1995]Akama,H., Johnson,C.A. and Colten,H.R.
    Human complement protein C2. Alternative splicing generates templates for secreted and intracellular C2 proteins
    J Biol Chem270, 2674-2678. PubMed  Europe PubMed DOI  R
    20. 1994
  20. [YEAR:15-2-1994]Cheng,J. and Volanakis,J.E.
    Alternatively spliced transcripts of the human complement C2 gene
    J Immunol152, 1774-1782. PubMed  Europe PubMed  R
  21. [YEAR:6-7-1993]
    Nomenclature for human complement component C2. WHO-IUIS Nomenclature Sub-Committee
    J Immunol Methods163, 1-2. PubMed  Europe PubMed DOI
    22. 1993
  22. [YEAR:1-7-1993]Ishii,Y., Zhu,Z.B., Macon,K.J. and Volanakis,J.E.
    Structure of the human C2 gene
    J Immunol151, 170-174. PubMed  Europe PubMed
  23. [YEAR:1-10-1993]Perkins,S.J. and Smith,K.F.
    Identity of the putative serine-proteinase fold in proteins of the complement system with nine relevant crystal structures
    Biochem J295, 109-114. PubMed  Europe PubMed  S
    24. 1992

  24. Nomenclature for human complement component C2. WHO-IUIS Nomenclature Sub-Committee
    Bull World Health Organ70, 527-530. PubMed  Europe PubMed
  25. Kam,C.M., Oglesby,T.J., Pangburn,M.K., Volanakis,J.E. and Powers,J.C.
    Substituted isocoumarins as inhibitors of complement serine proteases
    J Immunol149, 163-168. PubMed  Europe PubMed  I
    26. 1989
  26. [YEAR:15-3-1989]Horiuchi,T., Macon,K.J., Kidd,V.J. and Volanakis,J.E.
    cDNA cloning and expression of human complement component C2
    J Immunol142, 2105-2111. PubMed  Europe PubMed
    27. 1987
  27. [YEAR:15-3-1987]Kam,C.M., McRae,B.J., Harper,J.W., Niemann,M.A., Volanakis,J.E. and Powers,J.C.
    Human complement proteins D, C2, and B. Active site mapping with peptide thioester substrates
    J Biol Chem262, 3444-3451. PubMed  Europe PubMed
    28. 1984
  28. Bentley,D.R. and Porter,R.R.
    Isolation of cDNA clones for human complement component C2
    Proc Natl Acad Sci U S A81, 1212-1215. PubMed  Europe PubMed
    29. 1983
  29. Parkes,C., Gagnon,J. and Kerr,M.A.
    The reaction of iodine and thiol-blocking reagents with human complement components C2 and factor B. Purification and N- terminal amino acid sequence of a peptide from C2a containing a free thiol group
    Biochem J213, 201-209. PubMed  Europe PubMed

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