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Literature for peptidase S01.194: complement component C2a

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, I Inhibitor, R Splicing, E Expression, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. Ning,G., Huang,Y.L., Zhen,L.M., Xu,W.X., Li,X.J., Wu,L.N., Liu,Y., Xie,C. and Peng,L.<br>Prognostic Value of Complement Component 2 and Its Correlation with Immune Infiltrates in Hepatocellular Carcinoma<br>Biomed Res Int (2020) 2020, 3765937-3765937. PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2019
  2. Peng,M., Li,Z., Niu,D., Liu,X., Dong,Z. and Li,J.<br>Complement factor B/C2 in molluscs regulates agglutination and illuminates evolution of the Bf/C2 family<br>FASEB J (2019) 33, 13323-13333. PubMed  Europe PubMed DOI
    3. 2014
  3. Norton,A.W., Martini,P.G., Cook,L.C., Alderucci,S., Lundberg,D.M., Fish,S.M., Bedard,C., Gill,J., Tzianabos,A.O. and Concino,M.F.<br>Expression and purification methods for the production of recombinant human complement component c2<br>Methods Mol Biol (2014) 1100, 61-74. PubMed  Europe PubMed DOI  E
    4. 2012
  4. Forneris,F., Wu,J. and Gros,P.<br>The modular serine proteases of the complement cascade<br>Curr Opin Struct Biol (2012) 22, 333-341. PubMed  Europe PubMed DOI  V
  5. Kerr,M.A.<br>Complement component C2: the classical and lectin pathway C3/C5 convertases<br>[ISSN:978-0-12-407742-3] (2012) 3, 2863-2868. DOI
    6. 2011
  6. Laursen,N.S., Andersen,K.R., Braren,I., Spillner,E., Sottrup-Jensen,L. and Andersen,G.R.<br>Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex<br>EMBO J (2011) 30, 606-616. PubMed  Europe PubMed DOI
    7. 2010
  7. Martini,P.G., Cook,L.C., Alderucci,S., Norton,A.W., Lundberg,D.M., Fish,S.M., Langsetmo,K., Jonsson,G., Lood,C., Gullstrand,B., Zaleski,K.J., Savioli,N., Lottherand,J., Bedard,C., Gill,J., Concino,M.F., Heartlein,M.W., Truedsson,L., Powell,J.L. and Tzianabos,A.O.<br>Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases<br>BMC Immunol (2010) 11, 43-43. PubMed  Europe PubMed DOI  PMC  EPMC  E  U
    8. 2009
  8. Halili,M.A., Ruiz-Gomez,G., Le,G.T., Abbenante,G. and Fairlie,D.P.<br>Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activation<br>Biochemistry (2009) 48, 8466-8472. PubMed  Europe PubMed DOI
  9. Krishnan,V., Xu,Y., Macon,K., Volanakis,J.E. and Narayana,S.V.<br>The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation<br>Acta Crystallogr D Biol Crystallogr (2009) 65, 266-274. PubMed  Europe PubMed DOI  PMC  EPMC
    10. 2007
  10. Krishnan,V., Xu,Y., Macon,K., Volanakis,J.E. and Narayana,S.V.<br>The crystal structure of C2a, the catalytic fragment of classical pathway C3 and C5 convertase of human complement<br>J Mol Biol (2007) 367, 224-233. PubMed  Europe PubMed DOI  PMC  EPMC  S
  11. Wallis,R., Dodds,A.W., Mitchell,D.A., Sim,R.B., Reid,K.B. and Schwaeble,W.J.<br>Molecular interactions between MASP-2, C4, and C2 and their activation fragments leading to complement activation via the lectin pathway<br>J Biol Chem (2007) 282, 7844-7851. PubMed  Europe PubMed DOI
    12. 2006
  12. Milder,F.J., Raaijmakers,H.C., Vandeputte,M.D., Schouten,A., Huizinga,E.G., Romijn,R.A., Hemrika,W., Roos,A., Daha,M.R. and Gros,P.<br>Structure of complement component C2a: implications for convertase formation and substrate binding<br>Structure (2006) 14, 1587-1597. PubMed  Europe PubMed DOI  S
  13. Selander,B., Martensson,U., Weintraub,A., Holmstrom,E., Matsushita,M., Thiel,S., Jensenius,J.C., Truedsson,L. and Sjoholm,A.G.<br>Mannan-binding lectin activates C3 and the alternative complement pathway without involvement of C2<br>J Clin Invest (2006) 116, 1425-1434. PubMed  Europe PubMed DOI  PMC  EPMC
  14. Springer,T.A.<br>Complement and the multifaceted functions of VWA and integrin I domains<br>Structure (2006) 14, 1611-1616. PubMed  Europe PubMed DOI  PMC  EPMC
    15. 2004
  15. Kerr,M.A.<br>Complement component C2: the classical and lectin pathway C3/C5 convertases<br>[ISSN:0-12-079610-4] (2004) 2, 1627-1632.  V
    16. 2000
  16. [YEAR:24-3-2000]Inal,J.M. and Sim,R.B.<br>A Schistosoma protein, Sh-TOR, is a novel inhibitor of complement which binds human C2<br>FEBS Lett (24-3-2000) 470, 131-134. PubMed  Europe PubMed DOI
  17. [YEAR:17-1-2000]Jing,H., Xu,Y.Y., Carson,M., Moore,D., Macon,K.J., Volanakis,J.E. and Narayana,S.V.L.<br>New structural motifs on the chymotrypsin fold and their potential roles in complement factor B<br>EMBO J (17-1-2000) 19, 164-173. PubMed  Europe PubMed DOI  PMC  EPMC  S
  18. Sim,R.B. and Laich,A.<br>Serine proteases of the complement system<br>Biochem Soc Trans (2000) 28, 545-550. PubMed  Europe PubMed
    19. 1995
  19. [YEAR:10-2-1995]Akama,H., Johnson,C.A. and Colten,H.R.<br>Human complement protein C2. Alternative splicing generates templates for secreted and intracellular C2 proteins<br>J Biol Chem (10-2-1995) 270, 2674-2678. PubMed  Europe PubMed DOI  R
    20. 1994
  20. [YEAR:15-2-1994]Cheng,J. and Volanakis,J.E.<br>Alternatively spliced transcripts of the human complement C2 gene<br>J Immunol (15-2-1994) 152, 1774-1782. PubMed  Europe PubMed  R
    21. 1993
  21. [YEAR:6-7-1993]<br>Nomenclature for human complement component C2. WHO-IUIS Nomenclature Sub-Committee<br>J Immunol Methods (6-7-1993) 163, 1-2. PubMed  Europe PubMed DOI
  22. [YEAR:1-7-1993]Ishii,Y., Zhu,Z.B., Macon,K.J. and Volanakis,J.E.<br>Structure of the human C2 gene<br>J Immunol (1-7-1993) 151, 170-174. PubMed  Europe PubMed
  23. [YEAR:1-10-1993]Perkins,S.J. and Smith,K.F.<br>Identity of the putative serine-proteinase fold in proteins of the complement system with nine relevant crystal structures<br>Biochem J (1-10-1993) 295, 109-114. PubMed  Europe PubMed  PMC  EPMC  S
    24. 1992
  24. <br>Nomenclature for human complement component C2. WHO-IUIS Nomenclature Sub-Committee<br>Bull World Health Organ (1992) 70, 527-530. PubMed  Europe PubMed  PMC  EPMC
  25. Kam,C.M., Oglesby,T.J., Pangburn,M.K., Volanakis,J.E. and Powers,J.C.<br>Substituted isocoumarins as inhibitors of complement serine proteases<br>J Immunol (1992) 149, 163-168. PubMed  Europe PubMed  I
    26. 1989
  26. [YEAR:15-3-1989]Horiuchi,T., Macon,K.J., Kidd,V.J. and Volanakis,J.E.<br>cDNA cloning and expression of human complement component C2<br>J Immunol (15-3-1989) 142, 2105-2111. PubMed  Europe PubMed
    27. 1987
  27. [YEAR:15-3-1987]Kam,C.M., McRae,B.J., Harper,J.W., Niemann,M.A., Volanakis,J.E. and Powers,J.C.<br>Human complement proteins D, C2, and B. Active site mapping with peptide thioester substrates<br>J Biol Chem (15-3-1987) 262, 3444-3451. PubMed  Europe PubMed
    28. 1984
  28. Bentley,D.R. and Porter,R.R.<br>Isolation of cDNA clones for human complement component C2<br>Proc Natl Acad Sci U S A (1984) 81, 1212-1215. PubMed  Europe PubMed  PMC  EPMC
    29. 1983
  29. Parkes,C., Gagnon,J. and Kerr,M.A.<br>The reaction of iodine and thiol-blocking reagents with human complement components C2 and factor B. Purification and N- terminal amino acid sequence of a peptide from C2a containing a free thiol group<br>Biochem J (1983) 213, 201-209. PubMed  Europe PubMed  PMC  EPMC

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