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Literature for peptidase S01.134: myeloblastin

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, T Target, P Specificity, E Expression, V Review, M Mutation, I Inhibitor, L Localization. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Jerke,U., Eulenberg-Gustavus,C., Wagner,D.L., Schreiber,A. and Kettritz,R.
    CRISPR-Cas9 mediated proteinase 3 autoantigen deletion as a treatment strategy for anti-neutrophil cytoplasmic autoantibody-associated vasculitis
    Kidney Int PubMed  Europe PubMed DOI
    2. 2024
  2. Gartan,P., Khorsand,F., Mizar,P., Vahokovski,J.I., Cervantes,L.F., Haug,B.E., Brenk,R., Brooks,C.L., III and Reuter,N.
    Investigating Polypharmacology through Targeting Known Human Neutrophil Elastase Inhibitors to Proteinase 3
    J Chem Inf Model64, 621-626. PubMed  Europe PubMed DOI
  3. Hwang,T.L., Lin,J.Y., Kuo,L.M., Kumar Dhandabani,G. and Hsieh,P.W.
    Design and synthesis of sirtinol analogs as human neutrophil elastase inhibitors
    Bioorg Med Chem Lett97, 129544-129544. PubMed  Europe PubMed DOI  I
  4. Khorsand,F., Haug,B.E., Kursula,I., Reuter,N. and Brenk,R.
    Expression and purification of human neutrophil proteinase 3 from insect cells and characterization of ligand binding
    PLoS ONE19, e0294827-e0294827. PubMed  Europe PubMed DOI
  5. Zhu,H.Y., Wang,H.J. and Liu,P.
    Versatile roles for neutrophil proteinase 3 in hematopoiesis and inflammation
    Immunol Res73, 1-1. PubMed  Europe PubMed DOI
    6. 2022
  6. Basso,J., Zhang,J., Lasala,D., Rose,S.J., Chen,K.J. and Cipolla,D.
    An optimized method of extracting and quantifying active Neutrophil serine proteases from human whole blood cells
    PLoS ONE17, e0272575-e0272575. PubMed  Europe PubMed DOI
  7. Gomez-Alonso,I.S., Martinez-Garcia,S., Betanzos-Cabrera,G., Juarez,E., Sarabia-Leon,M.C., Herrera,M.T., Gomez-Chavez,F., Sanchez-Torres,L., Rodriguez-Martinez,S., Cancino-Diaz,M.E., Cancino,J. and Cancino-Diaz,J.C.
    Low Concentration of the Neutrophil Proteases Cathepsin G, Cathepsin B, Proteinase-3 and Metalloproteinase-9 Induce Biofilm Formation in Non-Biofilm-Forming Staphylococcus epidermidis Isolates
    Int J Mol Sci23, PubMed  Europe PubMed DOI
  8. Marino,S.F., Jerke,U., Rolle,S., Daumke,O. and Kettritz,R.
    Competitively disrupting the neutrophil-specific receptor-autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation
    J Biol Chem298, 101598-101598. PubMed  Europe PubMed DOI
  9. Nguyen,S.D., Maaninka,K., Mayranpaa,M.I., Baumann,M., Soliymani,R., Lee-Rueckert,M., Jauhiainen,M., Kovanen,P.T. and Oorni,K.
    Neutrophil proteinase 3 - An LDL- and HDL-proteolyzing enzyme with a potential to contribute to cholesterol accumulation in human atherosclerotic lesions
    Biochim Biophys Acta Mol Cell Biol Lipids1867, 159225-159225. PubMed  Europe PubMed DOI
    10. 2021
  10. Cheung,P., Schaffert,S., Chang,S.E., Dvorak,M., Donato,M., Macaubas,C., Foecke,M.H., Li,T.M., Zhang,L., Coan,J.P., Schulert,G.S., Grom,A.A., Henderson,L.A., Nigrovic,P.A., Elias,J.E., Gozani,O., Mellins,E.D., Khatri,P., Utz,P.J. and Kuo,A.J.
    Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation
    Nat Immunol22, 711-722. PubMed  Europe PubMed DOI
  11. Fazleen,A. and Wilkinson,T.
    The emerging role of proteases in alpha1-antitrypsin deficiency and beyond
    ERJ Open Res7, PubMed  Europe PubMed DOI
  12. Mustafa,Z., Zhanapiya,A., Kalbacher,H. and Burster,T.
    Neutrophil Elastase and Proteinase 3 Cleavage Sites Are Adjacent to the Polybasic Sequence within the Proteolytic Sensitive Activation Loop of the SARS-CoV-2 Spike Protein
    ACS Omega6, 7181-7185. PubMed  Europe PubMed DOI
  13. Patterson,E.K., Vanin Moreno,N., Fraser,D.D., Cepinskas,G., Iida,T. and Berard,R.A.
    A Proteinase 3 Contribution to Juvenile Idiopathic Arthritis-Associated Cartilage Damage
    Pathophysiology28, 320-327. PubMed  Europe PubMed DOI
  14. Weiss,S.A.I., Rehm,S.R.T., Perera,N.C., Biniossek,M.L., Schilling,O. and Jenne,D.E.
    Origin and Expansion of the Serine Protease Repertoire in the Myelomonocyte Lineage
    Int J Mol Sci22, PubMed  Europe PubMed DOI
  15. Yoshida,S., Hanai,S., Nakagomi,D., Kobayashi,K., Takahashi,K. and Furuya,F.
    Membranous Nephropathy with Proteinase 3-ANCA-associated Vasculitis Successfully Treated with Rituximab
    Intern Med60, 145-150. PubMed  Europe PubMed DOI
    16. 2020
  16. Akgun,E., Tuzuner,M.B., Sahin,B., Kilercik,M., Kulah,C., Cakiroglu,H.N., Serteser,M., Unsal,I. and Baykal,A.T.
    Proteins associated with neutrophil degranulation are upregulated in nasopharyngeal swabs from SARS-CoV-2 patients
    PLoS ONE15, e0240012-e0240012. PubMed  Europe PubMed DOI
  17. Basu,K., Karmakar,S., Sengupta,M., Roychowdhury,A., Ghosh,A. and Bandopadhyay,M.
    Pediatric lupus nephritis - An evil cousin of its adult counterpart: A single-center based experience from a tertiary care hospital of Eastern India
    Indian J Pathol Microbiol63, 397-404. PubMed  Europe PubMed DOI
  18. Fu,Z., Akula,S., Thorpe,M. and Hellman,L.
    Potent and broad but not unselective cleavage of cytokines and chemokines by human neutrophil elastase and proteinase 3
    Int J Mol Sci21, PubMed  Europe PubMed DOI
  19. Moore,R.M., Katri,R., Kumar,D., Mansour,J.M., Mercer,B. and Moore,J.J.
    alpha-Lipoic acid blocks the GMCSF induced protease/protease inhibitor spectrum associated with fetal membrane weakening in-vitro
    Placenta97, 79-88. PubMed  Europe PubMed DOI
  20. N'Guessan,K., Grzywa,R., Seren,S., Gabant,G., Juliano,M.A., Moniatte,M., Van Dorsselaer,A., Bieth,J., Kellenberger,C., Gauthier,F., Wysocka,M., Lesner,A., Sienczyk,M., Cadene,M. and Korkmaz,B.
    Human proteinase 3 resistance to inhibition extends to alpha-2 macroglobulin
    FEBS J PubMed  Europe PubMed DOI
    21. 2019
  21. Grzywa,R., Lesner,A., Korkmaz,B. and Sienczyk,M.
    Proteinase 3 phosphonic inhibitors
    Biochimie166, 142-149. PubMed  Europe PubMed DOI  I
  22. Maximova,K., Reuter,N. and Trylska,J.
    Peptidomimetic inhibitors targeting the membrane-binding site of the neutrophil proteinase 3
    Biochim Biophys Acta Biomembr1861, 1502-1509. PubMed  Europe PubMed DOI
  23. Newby,P.R., Crossley,D., Crisford,H., Stockley,J.A., Mumford,R.A., Carter,R.I., Bolton,C.E., Hopkinson,N.S., Mahadeva,R., Steiner,M.C., Wilkinson,T.M.A., Sapey,E. and Stockley,R.A.
    A specific proteinase 3 activity footprint in alpha1-antitrypsin deficiency
    ERJ Open Res5, PubMed  Europe PubMed DOI
  24. Tian,S., Swedberg,J.E., Li,C.Y., Craik,D.J. and de Veer,S.J.
    Iterative optimization of the cyclic peptide SFTI-1 yields potent inhibitors of neutrophil proteinase 3
    ACS Med Chem Lett10, 1234-1239. PubMed  Europe PubMed DOI
    25. 2018
  25. Fu,Z., Thorpe,M., Akula,S., Chahal,G. and Hellman,L.T.
    Extended cleavage specificity of human neutrophil elastase, human proteinase 3, and their distant ortholog clawed frog PR3-three elastases with similar primary but different extended specificities and stability
    Front Immunol9, 2387-2387. PubMed  Europe PubMed DOI  P
  26. Guarino,C., Gruba,N., Grzywa,R., Dyguda-Kazimierowicz,E., Hamon,Y., Legowska,M., Skorenski,M., Dallet-Choisy,S., Marchand-Adam,S., Kellenberger,C., Jenne,D.E., Sienczyk,M., Lesner,A., Gauthier,F. and Korkmaz,B.
    Exploiting the S4-S5 specificity of human neutrophil proteinase 3 to improve the potency of peptidyl di(chlorophenyl)-phosphonate ester inhibitors: a kinetic and molecular modeling analysis
    J Med Chem61, 1858-1870. PubMed  Europe PubMed DOI  I
  27. Gudmann,N.S., Manon-Jensen,T., Sand,J.M.B., Diefenbach,C., Sun,S., Danielsen,A., Karsdal,M.A. and Leeming,D.J.
    Lung tissue destruction by proteinase 3 and cathepsin G mediated elastin degradation is elevated in chronic obstructive pulmonary disease
    Biochem Biophys Res Commun503, 1284-1290. PubMed  Europe PubMed DOI
  28. Popow-Stellmaszyk,J., Bajorowicz,B., Malankowska,A., Wysocka,M., Klimczuk,T., Zaleska-Medynska,A. and Lesner,A.
    Design, synthesis, and enzymatic evaluation of novel ZnO quantum dot-based assay for detection of proteinase 3 activity
    Bioconjug Chem29, 1576-1583. PubMed  Europe PubMed DOI  A
  29. Seren,S., Rashed Abouzaid,M., Eulenberg-Gustavus,C., Hirschfeld,J., Nasr Soliman,H., Jerke,U., N'Guessan,K., Dallet-Choisy,S., Lesner,A., Lauritzen,C., Schacher,B., Eickholz,P., Nagy,N., Szell,M., Croix,C., Viaud-Massuard,M.C., Al Farraj Aldosari,A., Ragunatha,S., Ibrahim Mostafa,M., Giampieri,F., Battino,M., Cornillier,H., Lorette,G., Stephan,J.L., Goizet,C., Pedersen,J., Gauthier,F., Jenne,D.E., Marchand-Adam,S., Chapple,I.L., Kettritz,R. and Korkmaz,B.
    Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis
    J Biol Chem293, 12415-12428. PubMed  Europe PubMed DOI
  30. Tacnet-Delorme,P., Gabillet,J., Chatfield,S., Thieblemont,N., Frachet,P. and Witko-Sarsat,V.
    Proteinase 3 interferes with C1q-mediated clearance of apoptotic cells
    Front Immunol9, 818-818. PubMed  Europe PubMed DOI
  31. Witko-Sarsat,V. and Thieblemont,N.
    Granulomatosis with polyangiitis (Wegener granulomatosis): a proteinase-3 driven disease?
    Joint Bone Spine85, 185-189. PubMed  Europe PubMed DOI
    32. 2017
  32. Benarafa,C. and Simon,H.U.
    Role of granule proteases in the life and death of neutrophils
    Biochem Biophys Res Commun482, 473-481. PubMed  Europe PubMed DOI  V
  33. Martin,K.R. and Witko-Sarsat,V.
    Proteinase 3: the odd one out that became an autoantigen
    J Leukoc Biol102, 689-698. PubMed  Europe PubMed DOI  V
  34. Maximova,K., Venken,T., Reuter,N. and Trylska,J.
    d-Peptides as inhibitors of PR3-membrane interactions
    Biochim Biophys Acta1860, 458-466. PubMed  Europe PubMed DOI
  35. Witko-Sarsat,V. and Thieblemont,N.
    Granulomatosis with polyangiitis (Wegener): a proteinase 3-driven disease?
    Rev Rhum Monogr84, 236-240. DOI
    36. 2016
  36. Craciun,I., Fenner,A.M. and Kerns,R.J.
    N-Arylacyl O-sulfonated aminoglycosides as novel inhibitors of human neutrophil elastase, cathepsin G and proteinase 3
    Glycobiology26, 701-709. PubMed  Europe PubMed DOI  I
  37. Kim,Y.C., Choi,Y.S., Alam,J., Kim,Y.J., Baek,K.J., Koh,J., Song,Y.W., Chung,D.H. and Choi,Y.
    Induction of proteinase 3-anti-neutrophil cytoplasmic autoantibodies by proteinase 3-homologous bacterial protease in mice
    Immunol Res64, 438-444. PubMed  Europe PubMed DOI
  38. Korkmaz,B., Lesner,A., Guarino,C., Wysocka,M., Kellenberger,C., Watier,H., Specks,U., Gauthier,F. and Jenne,D.E.
    Inhibitors and antibody fragments as potential anti-inflammatory therapeutics targeting neutrophil proteinase 3 in human disease
    Pharmacol Rev68, 603-630. PubMed  Europe PubMed DOI  V  T
  39. Martin,K.R., Kantari-Mimoun,C., Yin,M., Pederzoli-Ribeil,M., Angelot-Delettre,F., Ceroi,A., Grauffel,C., Benhamou,M., Reuter,N., Saas,P., Frachet,P., Boulanger,C.M. and Witko-Sarsat,V.
    Proteinase 3 is a phosphatidylserine-binding protein that affects the production and function of microvesicles
    J Biol Chem291, 10476-10489. PubMed  Europe PubMed DOI
  40. Mkaouar,H., Akermi,N., Mariaule,V., Boudebbouze,S., Gaci,N., Szukala,F., Pons,N., Marquez,J., Gargouri,A., Maguin,E. and Rhimi,M.
    Siropins, novel serine protease inhibitors from gut microbiota acting on human proteases involved in inflammatory bowel diseases
    Microb Cell Fact15, 201-201. PubMed  Europe PubMed DOI
    41. 2015
  41. Hwang,T.L., Wang,W.H., Wang,T.Y., Yu,H.P. and Hsieh,P.W.
    Synthesis and pharmacological characterization of 2-aminobenzaldehyde oxime analogs as dual inhibitors of neutrophil elastase and proteinase 3
    Bioorg Med Chem23, 1123-1134. PubMed  Europe PubMed DOI  I
  42. Liu,G.-H., Deng,L. and Peng,L.-F.
    Research advances on proteinase 3 and its relationship with diseases
    Prog Biochem Biophys42, 244-253. DOI  V
    43. 2014
  43. Budnjo,A., Narawane,S., Grauffel,C., Schillinger,A.S., Fossen,T., Reuter,N. and Haug,B.E.
    Reversible ketomethylene-based inhibitors of human neutrophil proteinase 3
    J Med Chem57, 9396-9408. PubMed  Europe PubMed DOI  I
  44. Grzywa,R., Burchacka,E., Lecka,M., Winiarski,L., Walczak,M., Lupicka-Slowik,A., Wysocka,M., Burster,T., Bobrek,K., Csencsits-Smith,K., Lesner,A. and Sienczyk,M.
    Synthesis of novel phosphonic-type activity-based probes for neutrophil serine proteases and their application in spleen lysates of different organisms
    Chembiochem15, 2605-2612. PubMed  Europe PubMed DOI  I
  45. Guarino,C., Legowska,M., Epinette,C., Kellenberger,C., Dallet-Choisy,S., Sienczyk,M., Gabant,G., Cadene,M., Zoidakis,J., Vlahou,A., Wysocka,M., Marchand-Adam,S., Jenne,D.E., Lesner,A., Gauthier,F. and Korkmaz,B.
    New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases
    J Biol Chem289, 31777-31791. PubMed  Europe PubMed DOI  P  L  I
  46. Narawane,S., Budnjo,A., Grauffel,C., Haug,B.E. and Reuter,N.
    In silico design, synthesis, and assays of specific substrates for proteinase 3: influence of fluorogenic and charged groups
    J Med Chem57, 1111-1115. PubMed  Europe PubMed DOI  A  P
  47. Schillinger,A.S., Grauffel,C., Khan,H.M., Halskau,O. and Reuter,N.
    Two homologous neutrophil serine proteases bind to POPC vesicles with different affinities: when aromatic amino acids matter
    Biochim Biophys Acta1838, 3191-3202. PubMed  Europe PubMed DOI
  48. Stapels,D.A., Ramyar,K.X., Bischoff,M., von Kockritz-Blickwede,M., Milder,F.J., Ruyken,M., Eisenbeis,J., McWhorter,W.J., Herrmann,M., Van Kessel,K.P., Geisbrecht,B.V. and Rooijakkers,S.H.
    Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors
    Proc Natl Acad Sci U S A111, 13187-13192. PubMed  Europe PubMed DOI  S
    49. 2013
  49. Hinkofer,L.C., Seidel,S.A., Korkmaz,B., Silva,F., Hummel,A.M., Braun,D., Jenne,D.E. and Specks,U.
    A monoclonal antibody (MCPR3-7) interfering with the activity of proteinase 3 by an allosteric mechanism
    J Biol Chem288, 26635-26648. PubMed  Europe PubMed DOI
  50. Korkmaz,B., Jenne,D.E. and Gauthier,F.
    Relevance of the mouse model as a therapeutic approach for neutrophil proteinase 3-associated human diseases
    Int Immunopharmacol17, 1198-1205. PubMed  Europe PubMed DOI
  51. Korkmaz,B., Kellenberger,C., Viaud-Massuard,M.C. and Gauthier,F.
    Selective inhibitors of human neutrophil proteinase 3
    Curr Pharm Des19, 966-976. PubMed  Europe PubMed  I
  52. Kuckleburg,C.J. and Newman,P.J.
    Neutrophil Proteinase 3 Acts on Protease-Activated Receptor-2 to Enhance Vascular Endothelial Cell Barrier Function
    Arterioscler Thromb Vasc Biol33, 275-284. PubMed  Europe PubMed DOI
  53. Kwon,K.J., Cho,K.S., Kim,J.N., Kim,M.K., Lee,E.J., Kim,S.Y., Jeon,S.J., Kim,K.C., Han,J.E., Kang,Y.S., Kim,S., Kim,H.Y., Han,S.H., Bahn,G., Choi,J.W. and Shin,C.Y.
    Proteinase 3 induces oxidative stress-mediated neuronal death in rat primary cortical neuron
    Neurosci Lett548, 67-72. PubMed  Europe PubMed DOI
  54. Popow-Stellmaszyk,J., Wysocka,M., Lesner,A., Korkmaz,B. and Rolka,K.
    A new proteinase 3 substrate with improved selectivity over human neutrophil elastase
    Anal Biochem442, 75-82. PubMed  Europe PubMed DOI  A
    55. 2012
  55. Bae,S., Kang,T., Hong,J., Lee,S., Choi,J., Jhun,H., Kwak,A., Hong,K., Kim,E., Jo,S. and Kim,S.
    Contradictory functions (activation/termination) of neutrophil proteinase 3 enzyme (PR3) in interleukin-33 biological activity
    J Biol Chem287, 8205-8213. PubMed  Europe PubMed DOI
  56. Bae,S., Choi,J., Hong,J., Jhun,H., Hong,K., Kang,T., Song,K., Jeong,S., Yum,H. and Kim,S.
    Neutrophil proteinase 3 induces diabetes in a mouse model of glucose tolerance
    Endocr Res37, 35-45. PubMed  Europe PubMed DOI
  57. Brea,D., Meurens,F., Dubois,A.V., Gaillard,J., Chevaleyre,C., Jourdan,M.L., Winter,N., Arbeille,B., Si-Tahar,M., Gauthier,F. and Attucci,S.
    The pig as a model for investigating the role of neutrophil serine proteases in human inflammatory lung diseases
    Biochem J447, 363-370. PubMed  Europe PubMed DOI
  58. Dubois,A.V., Gauthier,A., Brea,D., Varaigne,F., Diot,P., Gauthier,F. and Attucci,S.
    Influence of DNA on the activities and inhibition of neutrophil serine proteases in cystic fibrosis sputum
    Am J Respir Cell Mol Biol47, 80-86. PubMed  Europe PubMed DOI
  59. Epinette,C., Croix,C., Jaquillard,L., Marchand-Adam,S., Kellenberger,C., Lalmanach,G., Cadene,M., Viaud-Massuard,M.C., Gauthier,F. and Korkmaz,B.
    A selective reversible azapeptide inhibitor of human neutrophil proteinase 3 derived from a high affinity FRET substrate
    Biochem Pharmacol83, 788-796. PubMed  Europe PubMed DOI  I
  60. Heinz,A., Jung,M.C., Jahreis,G., Rusciani,A., Duca,L., Debelle,L., Weiss,A.S., Neubert,R.H. and Schmelzer,C.E.
    The action of neutrophil serine proteases on elastin and its precursor
    Biochimie94, 192-202. PubMed  Europe PubMed DOI  P
  61. Korkmaz,B., Attucci,S., Epinette,C., Pitois,E., Jourdan,M.L., Juliano,L. and Gauthier,F.
    Measurement of neutrophil elastase, proteinase 3, and cathepsin G activities using intramolecularly quenched fluorogenic substrates
    Methods Mol Biol844, 125-138. PubMed  Europe PubMed DOI  A
  62. Kuckleburg,C.J., Tilkens,S.B., Santoso,S. and Newman,P.J.
    Proteinase 3 contributes to transendothelial migration of NB1-positive neutrophils
    J Immunol188, 2419-2426. PubMed  Europe PubMed DOI
  63. Monleon,L.M., Diez-Garcia,F., Zamora,H., Anaya,J., Grande,M., De Diego,J.G. and David Rodriguez,F.
    In vitro evaluation of the antielastase activity of polycyclic beta-lactams
    Bioorg Chem45, 29-35. PubMed  Europe PubMed DOI  I
  64. Rao,N.V. and Hoidal,J.R.
    Myeloblastin
    [ISSN:978-0-12-407742-3]3, 2666-2675. DOI
  65. Wiedl,T., Collaud,S., Hillinger,S., Arni,S., Burgess,C., Kroll,W., Schraml,P., Soltermann,A., Moch,H. and Weder,W.
    KRAS Mutation is associated with elevated myeloblastin activity in human lung adenocarcinoma
    Cancer Genomics Proteomics9, 51-54. PubMed  Europe PubMed  T
  66. Wysocka,M., Lesner,A., Popow,J., Legowska,M. and Rolka,K.
    Pegylated fluorescent peptides as substrates of proteolytic enzymes
    Protein Pept Lett19, 1237-1244. PubMed  Europe PubMed  A  P
  67. Wysocka,M., Lesner,A., Gruba,N., Korkmaz,B., Gauthier,F., Kitamatsu,M., Legowska,A. and Rolka,K.
    Three wavelength substrate system of neutrophil serine proteinases
    Anal Chem84, 7241-7248. PubMed  Europe PubMed DOI  A
    68. 2011
  68. Jegot,G., Derache,C., Castella,S., Lahouassa,H., Pitois,E., Jourdan,M.L., Remold-O'Donnell,E., Kellenberger,C., Gauthier,F. and Korkmaz,B.
    A substrate-based approach to convert serpinB1 into a specific inhibitor of proteinase 3, the Wegener's granulomatosis autoantigen
    FASEB J25, 3019-3031. PubMed  Europe PubMed DOI
  69. Kessenbrock,K., Dau,T. and Jenne,D.E.
    Tailor-made inflammation: how neutrophil serine proteases modulate the inflammatory response
    J Mol Med (Berl)89, 23-28. PubMed  Europe PubMed DOI
  70. Relle,M., Thomaidis,T., Galle,P.R. and Schwarting,A.
    Comparative aspects of murine proteinase 3
    Rheumatol Int31, 1105-1111. PubMed  Europe PubMed DOI
    71. 2010
  71. Bae,S., Choi,J., Hong,J., Lee,S., Her,E., Choi,W., Kim,S., Choi,Y. and Kim,S.
    Generation of anti-proteinase 3 monoclonal antibodies and development of immunological methods to detect endogenous proteinase 3
    Hybridoma (Larchmt)29, 17-26. PubMed  Europe PubMed DOI
  72. Broemstrup,T. and Reuter,N.
    How does proteinase 3 interact with lipid bilayers?
    Phys Chem Chem Phys12, 7487-7496. PubMed  Europe PubMed DOI
  73. Dou,D., He,G., Kuang,R., Fu,Q., Venkataraman,R. and Groutas,W.C.
    Effects of structure on inhibitory activity in a series of mechanism-based inhibitors of human neutrophil elastase
    Bioorg Med Chem18, 6646-6650. PubMed  Europe PubMed DOI  I
  74. Dou,D., He,G., Li,Y., Lai,Z., Wei,L., Alliston,K.R., Lushington,G.H., Eichhorn,D.M. and Groutas,W.C.
    Utilization of the 1,2,3,5-thiatriazolidin-3-one 1,1-dioxide scaffold in the design of potential inhibitors of human neutrophil proteinase 3
    Bioorg Med Chem18, 1093-1102. PubMed  Europe PubMed DOI  I
  75. Hajjar,E., Broemstrup,T., Kantari,C., Witko-Sarsat,V. and Reuter,N.
    Structures of human proteinase 3 and neutrophil elastase - so similar yet so different
    FEBS J277, 2238-2254. PubMed  Europe PubMed DOI
  76. Korkmaz,B., Horwitz,M.S., Jenne,D.E. and Gauthier,F.
    Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases
    Pharmacol Rev62, 726-759. PubMed  Europe PubMed DOI  V  T
  77. Kuhl,A., Korkmaz,B., Utecht,B., Kniepert,A., Schonermarck,U., Specks,U. and Jenne,D.E.
    Mapping of conformational epitopes on human proteinase 3, the autoantigen of Wegener's granulomatosis
    J Immunol185, 387-399. PubMed  Europe PubMed DOI
  78. Pederzoli-Ribeil,M., Maione,F., Cooper,D., Al-Kashi,A., Dalli,J., Perretti,M. and D'Acquisto,F.
    Design and characterization of a cleavage-resistant annexin A1 mutant to control inflammation in the microvasculature
    Blood116, 4288-4296. PubMed  Europe PubMed DOI
  79. Wysocka,M., Lesner,A., Majkowska,G., Legowska,A., Guzow,K., Rolka,K. and Wiczk,W.
    The new fluorogenic substrates of neutrophil proteinase 3 optimized in prime site region
    Anal Biochem399, 196-201. PubMed  Europe PubMed DOI  P
  80. Wysocka,M., Lesner,A., Guzow,K., Kulczycka,J., Legowska,A., Wiczk,W. and Rolka,K.
    Highly specific substrates of proteinase 3 containing 3-(2-benzoxazol-5-yl)-l-alanine and their application for detection of this enzyme in human serum
    Anal Chem82, 3883-3889. PubMed  Europe PubMed DOI  A  P
    81. 2009
  81. Hajjar,E., Dejaegere,A. and Reuter,N.
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