Literature for peptidase S01.119: trypsin-2 type C

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Pharma

(Topics flags: S Structure, P Specificity, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2012

Baird,T.T., Jr. and Craik,C.S. Trypsin [ISSN:978-0-12-407742-3] (2012) 3, 2594-2600. DOI

2004

Halfon,S., Baird,T.T., Jr. and Craik,C.S. Trypsin [ISSN:0-12-079610-4] (2004) 2, 1483-1488. V
Hara,H. and Shiota,H. Differential increases in syntheses of newly identified trypsinogen 2 isoforms by dietary protein in rat pancreas Exp Biol Med (Maywood) (2004) 229, 772-780. PubMed Europe PubMed

2000

[YEAR:5-7-2000]Harris,J.L., Backes,B.J., Leonetti,F., Mahrus,S., Ellman,J.A. and Craik,C.S. Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries Proc Natl Acad Sci U S A (5-7-2000) 97, 7754-7759. PubMed Europe PubMed DOI PMC EPMC P

1999

Pasternak,A., Ringe,D. and Hedstrom,L. Comparison of anionic and cationic trypsinogens: the anionic activation domain is more flexible in solution and differs in its mode of BPTI binding in the crystal structure Protein Sci (1999) 8, 253-258. PubMed Europe PubMed DOI PMC EPMC

1996

Halfon,S. and Craik,C.S. Regulation of proteolytic activity by engineered tridentate metal binding loops J Am Chem Soc (1996) 118, 1227-1228. DOI E

1995

Corey,D.R., Willett,W.S., Coombs,G.S. and Craik,C.S. Trypsin specificity increased through substrate-assisted catalysis Biochemistry (1995) 34, 11521-11527. PubMed Europe PubMed DOI
Perona,J.J., Hedstrom,L., Rutter,W.J. and Fletterick,R.J. Structural origins of substrate discrimination in trypsin and chymotrypsin Biochemistry (1995) 34, 1489-1499. PubMed Europe PubMed

1994

McGrath,M.E., Erpel,T., Bystroff,C. and Fletterick,R.J. Macromolecular chelation as an improved mechanism of protease inhibition: structure of the ecotin-trypsin complex EMBO J (1994) 13, 1502-1507. PubMed Europe PubMed PMC EPMC S
Perona,J.J., Hedstrom,L., Wagner,R.L., Rutter,W.J., Craik,C.S. and Fletterick,R.J. Exogenous acetate reconstitutes the enzymatic activity of trypsin Asp189Ser Biochemistry (1994) 33, 3252-3259. PubMed Europe PubMed

1993

McGrath,M.E., Haymore,B.L., Summers,N.L., Craik,C.S. and Fletterick,R.J. Structure of an engineered, metal-actuated switch in trypsin Biochemistry (1993) 32, 1914-1919. PubMed Europe PubMed S
[YEAR:5-4-1993]Perona,J.J., Tsu,C.A., Craik,C.S. and Fletterick,R.J. Crystal structures of rat anionic trypsin complexed with the protein inhibitors APPI and BPTI J Mol Biol (5-4-1993) 230, 919-933. PubMed Europe PubMed DOI S

1992

[YEAR:31-3-1992]McGrath,M.E., Vasquez,J.R., Craik,C.S., Yang,A.S., Honig,B. and Fletterick,R.J. Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214 Biochemistry (31-3-1992) 31, 3059-3064. PubMed Europe PubMed DOI

1991

Earnest,T., Fauman,E., Craik,C.S. and Stroud,R. 1.59 A structure of trypsin at 120 K: comparison of low temperature and room temperature structures Proteins (1991) 10, 171-187. PubMed Europe PubMed DOI S
Wilke,M.E., Higaki,J.N., Craik,C.S. and Fletterick,R.J. Crystal structure of rat trypsin-S195C at -150 degrees C. Analysis of low activity of recombinant and semisynthetic thiol proteases J Mol Biol (1991) 219, 511-523. PubMed Europe PubMed S

1990

Evnin,L.B., Vasquez,J.R. and Craik,C.S. Substrate specificity of trypsin investigated by using a genetic selection Proc Natl Acad Sci U S A (1990) 87, 6659-6663. PubMed Europe PubMed PMC EPMC
[YEAR:18-9-1990]Higaki,J.N., Haymore,B.L., Chen,S., Fletterick,R.J. and Craik,C.S. Regulation of serine protease activity by an engineered metal switch Biochemistry (18-9-1990) 29, 8582-8586. PubMed Europe PubMed

1989

McGrath,M.E., Wilke,M.E., Higaki,J.N., Craik,C.S. and Fletterick,R.J. Crystal structures of two engineered thiol trypsins Biochemistry (1989) 28, 9264-9270. PubMed Europe PubMed DOI S

1988

Graf,L., Hegyi,G., Liko,I., Hepp,J., Medzihradszky,K., Craik,C.S. and Rutter,W.J. Structural and functional integrity of specificity and catalytic sites of trypsin Int J Pept Protein Res (1988) 32, 512-518. PubMed Europe PubMed

1987

[YEAR:21-8-1987]Craik,C.S., Roczniak,S., Largman,C. and Rutter,W.J. The catalytic role of the active site aspartic acid in serine proteases Science (21-8-1987) 237, 909-913. PubMed Europe PubMed
Graf,L., Craik,C.S., Patthy,A., Roczniak,S., Fletterick,R.J. and Rutter,W.J. Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin Biochemistry (1987) 26, 2616-2623. PubMed Europe PubMed
Sprang,S., Standing,T., Fletterick,R.J., Stroud,R.M., Finer-Moore,J., Xuong,N.H., Hamlin,R., Rutter,W.J. and Craik,C.S. The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis Science (1987) 237, 905-909. PubMed Europe PubMed

1985

[YEAR:19-4-1985]Craik,C.S., Largman,C., Fletcher,T., Roczniak,S., Barr,P.J., Fletterick,R. and Rutter,W.J. Redesigning trypsin: alteration of substrate specificity Science (19-4-1985) 228, 291-297. PubMed Europe PubMed

1984

Craik,C.S., Choo,Q.L., Swift,G.H., Quinto,C., Macdonald,R.J. and Rutter,W.J. Structure of two related rat pancreatic trypsin genes J Biol Chem (1984) 259, 14255-14264. PubMed Europe PubMed

1973

Rinderknecht,H. and Geokas,M.C. Anionic and cationic trypsinogens (trypsins) in mammalian pancreas Enzyme (1973) 14, 116-130.