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Literature for peptidase S01.119: trypsin-2 type C

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Pharma

(Topics flags: S Structure, P Specificity, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2012
  1. Baird,T.T., Jr. and Craik,C.S.
    Trypsin
    [ISSN:978-0-12-407742-3]3, 2594-2600. DOI
    2. 2004
  2. Halfon,S., Baird,T.T., Jr. and Craik,C.S.
    Trypsin
    [ISSN:0-12-079610-4]2, 1483-1488.  V
  3. Hara,H. and Shiota,H.
    Differential increases in syntheses of newly identified trypsinogen 2 isoforms by dietary protein in rat pancreas
    Exp Biol Med (Maywood)229, 772-780. PubMed  Europe PubMed
    4. 2000
  4. [YEAR:5-7-2000]Harris,J.L., Backes,B.J., Leonetti,F., Mahrus,S., Ellman,J.A. and Craik,C.S.
    Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries
    Proc Natl Acad Sci U S A97, 7754-7759. PubMed  Europe PubMed DOI  P
    5. 1999
  5. Pasternak,A., Ringe,D. and Hedstrom,L.
    Comparison of anionic and cationic trypsinogens: the anionic activation domain is more flexible in solution and differs in its mode of BPTI binding in the crystal structure
    Protein Sci8, 253-258. PubMed  Europe PubMed DOI
    6. 1996
  6. Halfon,S. and Craik,C.S.
    Regulation of proteolytic activity by engineered tridentate metal binding loops
    J Am Chem Soc118, 1227-1228. DOI  E
    7. 1995
  7. Corey,D.R., Willett,W.S., Coombs,G.S. and Craik,C.S.
    Trypsin specificity increased through substrate-assisted catalysis
    Biochemistry34, 11521-11527. PubMed  Europe PubMed DOI
  8. Perona,J.J., Hedstrom,L., Rutter,W.J. and Fletterick,R.J.
    Structural origins of substrate discrimination in trypsin and chymotrypsin
    Biochemistry34, 1489-1499. PubMed  Europe PubMed
    9. 1994
  9. McGrath,M.E., Erpel,T., Bystroff,C. and Fletterick,R.J.
    Macromolecular chelation as an improved mechanism of protease inhibition: structure of the ecotin-trypsin complex
    EMBO J13, 1502-1507. PubMed  Europe PubMed  S
  10. Perona,J.J., Hedstrom,L., Wagner,R.L., Rutter,W.J., Craik,C.S. and Fletterick,R.J.
    Exogenous acetate reconstitutes the enzymatic activity of trypsin Asp189Ser
    Biochemistry33, 3252-3259. PubMed  Europe PubMed
    11. 1993
  11. McGrath,M.E., Haymore,B.L., Summers,N.L., Craik,C.S. and Fletterick,R.J.
    Structure of an engineered, metal-actuated switch in trypsin
    Biochemistry32, 1914-1919. PubMed  Europe PubMed  S
  12. [YEAR:5-4-1993]Perona,J.J., Tsu,C.A., Craik,C.S. and Fletterick,R.J.
    Crystal structures of rat anionic trypsin complexed with the protein inhibitors APPI and BPTI
    J Mol Biol230, 919-933. PubMed  Europe PubMed DOI  S
    13. 1992
  13. [YEAR:31-3-1992]McGrath,M.E., Vasquez,J.R., Craik,C.S., Yang,A.S., Honig,B. and Fletterick,R.J.
    Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214
    Biochemistry31, 3059-3064. PubMed  Europe PubMed DOI
    14. 1991
  14. Earnest,T., Fauman,E., Craik,C.S. and Stroud,R.
    1.59 A structure of trypsin at 120 K: comparison of low temperature and room temperature structures
    Proteins10, 171-187. PubMed  Europe PubMed DOI  S
  15. Wilke,M.E., Higaki,J.N., Craik,C.S. and Fletterick,R.J.
    Crystal structure of rat trypsin-S195C at -150 degrees C. Analysis of low activity of recombinant and semisynthetic thiol proteases
    J Mol Biol219, 511-523. PubMed  Europe PubMed  S
    16. 1990
  16. Evnin,L.B., Vasquez,J.R. and Craik,C.S.
    Substrate specificity of trypsin investigated by using a genetic selection
    Proc Natl Acad Sci U S A87, 6659-6663. PubMed  Europe PubMed
  17. [YEAR:18-9-1990]Higaki,J.N., Haymore,B.L., Chen,S., Fletterick,R.J. and Craik,C.S.
    Regulation of serine protease activity by an engineered metal switch
    Biochemistry29, 8582-8586. PubMed  Europe PubMed
    18. 1989
  18. McGrath,M.E., Wilke,M.E., Higaki,J.N., Craik,C.S. and Fletterick,R.J.
    Crystal structures of two engineered thiol trypsins
    Biochemistry28, 9264-9270. PubMed  Europe PubMed DOI  S
    19. 1988
  19. Graf,L., Hegyi,G., Liko,I., Hepp,J., Medzihradszky,K., Craik,C.S. and Rutter,W.J.
    Structural and functional integrity of specificity and catalytic sites of trypsin
    Int J Pept Protein Res32, 512-518. PubMed  Europe PubMed
    20. 1987
  20. [YEAR:21-8-1987]Craik,C.S., Roczniak,S., Largman,C. and Rutter,W.J.
    The catalytic role of the active site aspartic acid in serine proteases
    Science237, 909-913. PubMed  Europe PubMed
  21. Graf,L., Craik,C.S., Patthy,A., Roczniak,S., Fletterick,R.J. and Rutter,W.J.
    Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin
    Biochemistry26, 2616-2623. PubMed  Europe PubMed
  22. Sprang,S., Standing,T., Fletterick,R.J., Stroud,R.M., Finer-Moore,J., Xuong,N.H., Hamlin,R., Rutter,W.J. and Craik,C.S.
    The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis
    Science237, 905-909. PubMed  Europe PubMed
    23. 1985
  23. [YEAR:19-4-1985]Craik,C.S., Largman,C., Fletcher,T., Roczniak,S., Barr,P.J., Fletterick,R. and Rutter,W.J.
    Redesigning trypsin: alteration of substrate specificity
    Science228, 291-297. PubMed  Europe PubMed
    24. 1984
  24. Craik,C.S., Choo,Q.L., Swift,G.H., Quinto,C., Macdonald,R.J. and Rutter,W.J.
    Structure of two related rat pancreatic trypsin genes
    J Biol Chem259, 14255-14264. PubMed  Europe PubMed
    25. 1973
  25. Rinderknecht,H. and Geokas,M.C.
    Anionic and cationic trypsinogens (trypsins) in mammalian pancreas
    Enzyme14, 116-130.

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