Literature for peptidase S01.034: transmembrane peptidase, serine 4

(Topics flags: M Mutation, T Target, R Splicing, K Knockout, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2023
1. Feng,H., Yao,L., Zeng,Z., Jiang,L., Shang,Y., Wang,H., Li,L., Wang,Z., Wang,X., Yang,H., Zhao,Q., Ren,X., Zhang,T., Zhang,R., Guo,Y., Lu,Q., Hu,Q., Zhang,W., Ding,C., Shao,H., Cheng,G., Luo,Q. and Wen,G.
   Identification of Embryonic Chicken Proteases Activating Newcastle Disease Virus and Their Roles in the Pathogenicity of Virus Used as In Ovo Vaccine
   J Virol97, e0032423-e0032423. PubMed  Europe PubMed DOI
2. Kim,S.
   TMPRSS4, a type II transmembrane serine protease, as a potential therapeutic target in cancer
   Exp Mol Med55, 716-724. PubMed  Europe PubMed DOI  V
2022
3. Kerslake,R., Randeva,H.S., Jonigk,D., Werlein,C., Robertus,J.L., Katopodis,P., Jasker,P., Spandidos,D.A., Kyrou,I. and Karteris,E.
   Protein expression of transmembrane protease serine 4 in the gastrointestinal tract and in healthy, cancer, and SARSCoV2 infected lungs
   Mol Med Rep25, PubMed  Europe PubMed DOI
2020
4. Dong,Z.R., Sun,D., Yang,Y.F., Zhou,W., Wu,R., Wang,X.W., Shi,K., Yan,Y.C., Yan,L.J., Yao,C.Y., Chen,Z.Q., Zhi,X.T. and Li,T.
   TMPRSS4 Drives angiogenesis in hepatocellular carcinoma by promoting HB-EGF expression and proteolytic cleavage
   Hepatology72, 923-939. PubMed  Europe PubMed DOI
5. Voinsky,I. and Gurwitz,D.
   Smoking and COVID-19: Similar bronchial ACE2 and TMPRSS2 expression and higher TMPRSS4 expression in current versus never smokers
   Drug Dev Res81, 1073-1080. PubMed  Europe PubMed DOI
6. Wruck,W. and Adjaye,J.
   SARS-CoV-2 receptor ACE2 is co-expressed with genes related to transmembrane serine proteases, viral entry, immunity and cellular stress
   Sci Rep10, 21415-21415. PubMed  Europe PubMed DOI
2019
7. Keppner,A., Maric,D., Sergi,C., Ansermet,C., De Bellis,D., Kratschmar,D.V., Canonica,J., Klusonova,P., Fenton,R.A., Odermatt,A., Crambert,G., Hoogewijs,D. and Hummler,E.
   Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion
   Sci Rep9, 19540-19540. PubMed  Europe PubMed DOI
2018
8. Jianwei,Z., Qi,L., Quanquan,X., Tianen,W. and Qingwei,W.
   TMPRSS4 Upregulates TWIST1 expression through STAT3 activation to induce prostate cancer cell migration
   Pathol Oncol Res24, 251-257. PubMed  Europe PubMed DOI
2017
9. Li,X.M., Liu,W.L., Chen,X., Wang,Y.W., Shi,D.B., Zhang,H., Ma,R.R., Liu,H.T., Guo,X.Y., Hou,F., Li,M. and Gao,P.
   Overexpression of TMPRSS4 promotes tumor proliferation and aggressiveness in breast cancer
   Int J Mol Med39, 927-935. PubMed  Europe PubMed DOI
10. Seo,B.R., Min,K.J., Woo,S.M., Choe,M., Choi,K.S., Lee,Y.K., Yoon,G. and Kwon,T.K.
    Inhibition of cathepsin S induces mitochondrial ROS that sensitizes TRAIL-mediated apoptosis through p53-mediated downregulation of Bcl-2 and c-FLIP
    Antioxid Redox Signal27, 215-233. PubMed  Europe PubMed DOI  I
11. Tanabe,L.M. and List,K.
    The role of type II transmembrane serine protease-mediated signaling in cancer
    FEBS J284, 1421-1436. PubMed  Europe PubMed DOI  I
2016
12. de Aberasturi,A.L., Redrado,M., Villalba,M., Larzabal,L., Pajares,M.J., Garcia,J., Evans,S.R., Garcia-Ros,D., Bodegas,M.E., Lopez,L., Montuenga,L. and Calvo,A.
    TMPRSS4 induces cancer stem cell-like properties in lung cancer cells and correlates with ALDH expression in NSCLC patients
    Cancer Lett370, 165-176. PubMed  Europe PubMed DOI
13. Ilamathi,M., Hemanth,R., Nishanth,S. and Sivaramakrishnan,V.
    Identification of potential transmembrane protease serine 4 inhibitors as anti-cancer agents by integrated computational approach
    J Theor Biol389, 253-262. PubMed  Europe PubMed DOI  T  I
14. Kuhn,N., Bergmann,S., Kosterke,N., Lambertz,R.L., Keppner,A., van den Brand,J.M., Pohlmann,S., Weiss,S., Hummler,E., Hatesuer,B. and Schughart,K.
    The proteolytic activation of (H3N2) influenza A virus hemagglutinin is facilitated by different type II transmembrane serine proteases
    J Virol90, 4298-4307. PubMed  Europe PubMed DOI
2015
15. de Aberasturi,A.L. and Calvo,A.
    TMPRSS4: an emerging potential therapeutic target in cancer
    Br J Cancer112, 4-8. PubMed  Europe PubMed DOI  T
2014
16. Larzabal,L., de Aberasturi,A.L., Redrado,M., Rueda,P., Rodriguez,M.J., Bodegas,M.E., Montuenga,L.M. and Calvo,A.
    TMPRSS4 regulates levels of integrin alpha5 in NSCLC through miR-205 activity to promote metastasis
    Br J Cancer110, 764-774. PubMed  Europe PubMed DOI
17. Min,H.J., Lee,M.K., Lee,J.W. and Kim,S.
    TMPRSS4 induces cancer cell invasion through pro-uPA processing
    Biochem Biophys Res Commun446, 1-7. PubMed  Europe PubMed DOI
18. Min,H.J., Lee,Y., Zhao,X.F., Park,Y.K., Lee,M.K., Lee,J.W. and Kim,S.
    TMPRSS4 upregulates uPA gene expression through JNK signaling activation to induce cancer cell invasion
    Cell Signal26, 398-408. PubMed  Europe PubMed DOI
19. Shi,G., Yang,X., Dai,B., Zhang,H., Shen,Y., Zhu,Y., Zhu,Y., Xiao,W., Ma,C., Wen,L., Qin,X., Cao,D. and Ye,D.
    Clinical significance of TMPRSS4 in prostate cancer
    Int J Clin Exp Pathol7, 8053-8058. PubMed  Europe PubMed
2013
20. Kang,S., Min,H.J., Kang,M.S., Jung,M.G. and Kim,S.
    Discovery of novel 2-hydroxydiarylamide derivatives as TMPRSS4 inhibitors
    Bioorg Med Chem Lett23, 1748-1751. PubMed  Europe PubMed DOI  I
21. Lahiry,P., Racacho,L., Wang,J., Robinson,J., Gloor,G.B., Rupar,C.A., Siu,V.M., Bulman,D.E. and Hegele,R.A.
    A mutation in the serine protease TMPRSS4 in a novel pediatric neurodegenerative disorder
    Orphanet J Rare Dis8, 126-126. PubMed  Europe PubMed DOI  M
22. Takahashi,T., Uehara,H. and Izumi,K.
    Inhibitory effect of soluble EP2 receptor on ovarian tumor growth in nude mice and utility of TMPRSS4 as a combinatorial molecular target
    Int J Oncol43, 416-424. PubMed  Europe PubMed DOI  T
2012
23. Ohler,A. and Becker-Pauly,C.
    TMPRSS4 is a type II transmembrane serine protease involved in cancer and viral infections
    Biol Chem393, 907-914. PubMed  Europe PubMed DOI  V
24. Passero,C.J., Mueller,G.M., Myerburg,M.M., Carattino,M.D., Hughey,R.P. and Kleyman,T.R.
    TMPRSS4-dependent activation of the epithelial sodium channel requires cleavage of the gamma-subunit distal to the furin cleavage site
    Am J Physiol Renal Physiol302, F1-F8. PubMed  Europe PubMed DOI
2011
25. Antalis,T.M., Bugge,T.H. and Wu,Q.
    Membrane-anchored serine proteases in health and disease
    Prog Mol Biol Transl Sci99, 1-50. PubMed  Europe PubMed DOI  V
26. Ohler,A. and Becker-Pauly,C.
    Morpholino knockdown of the ubiquitously expressed transmembrane serine protease TMPRSS4a in zebrafish embryos exhibits severe defects in organogenesis and cell adhesion
    Biol Chem392, 653-664. PubMed  Europe PubMed DOI  K
2010
27. Bertram,S., Glowacka,I., Blazejewska,P., Soilleux,E., Allen,P., Danisch,S., Steffen,I., Choi,S.Y., Park,Y., Schneider,H., Schughart,K. and Pohlmann,S.
    TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells
    J Virol84, 10016-10025. PubMed  Europe PubMed DOI
28. Bertram,S., Glowacka,I., Steffen,I., Kuhl,A. and Pohlmann,S.
    Novel insights into proteolytic cleavage of influenza virus hemagglutinin
    Rev Med Virol20, 298-310. PubMed  Europe PubMed DOI
29. Kim,S., Kang,H.Y., Nam,E.H., Choi,M.S., Zhao,X.F., Hong,C.S., Lee,J.W., Lee,J.H. and Park,Y.K.
    TMPRSS4 induces invasion and epithelial-mesenchymal transition through upregulation of integrin alpha5 and its signaling pathways
    Carcinogenesis31, 597-606. PubMed  Europe PubMed DOI
2009
30. Chaipan,C., Kobasa,D., Bertram,S., Glowacka,I., Steffen,I., Tsegaye,T.S., Takeda,M., Bugge,T.H., Kim,S., Park,Y., Marzi,A. and Pohlmann,S.
    Proteolytic activation of the 1918 influenza virus hemagglutinin
    J Virol83, 3200-3211. PubMed  Europe PubMed DOI
2008
31. Garcia-Caballero,A., Dang,Y., He,H. and Stutts,M.J.
    ENaC Proteolytic regulation by channel-activating protease 2
    J Gen Physiol132, 521-535. PubMed  Europe PubMed DOI
32. Jung,H., Lee,K.P., Park,S.J., Park,J.H., Jang,Y.S., Choi,S.Y., Jung,J.G., Jo,K., Park,D.Y., Yoon,J.H., Park,J.H., Lim,D.S., Hong,G.R., Choi,C., Park,Y.K., Lee,J.W., Hong,H.J., Kim,S. and Park,Y.W.
    TMPRSS4 promotes invasion, migration and metastasis of human tumor cells by facilitating an epithelial-mesenchymal transition
    Oncogene27, 2635-2647. PubMed  Europe PubMed DOI
2007
33. Planes,C. and Caughey,G.H.
    Regulation of the epithelial Na+ channel by peptidases
    Curr Top Dev Biol78, 23-46. PubMed  Europe PubMed DOI
2006
34. [YEAR:8-3-2006]Andreasen,D., Vuagniaux,G., Fowler-Jaeger,N., Hummler,E. and Rossier,B.C.
    Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1
    J Am Soc Nephrol17, 968-976. PubMed  Europe PubMed DOI
35. Kleyman,T.R., Myerburg,M.M. and Hughey,R.P.
    Regulation of ENaCs by proteases: an increasingly complex story
    Kidney Int70, 1391-1392. PubMed  Europe PubMed DOI
2005
36. Kebebew,E., Peng,M., Reiff,E., Duh,Q.Y., Clark,O.H. and McMillan,A.
    ECM1 and TMPRSS4 are diagnostic markers of malignant thyroid neoplasms and improve the accuracy of fine needle aspiration biopsy
    Ann Surg242, 353-361. PubMed  Europe PubMed DOI
37. Yamada,H., Shinmura,K., Tsuneyoshi,T. and Sugimura,H.
    Effect of splice-site polymorphisms of the TMPRSS4, NPHP4 and ORCTL4 genes on their mRNA expression
    J Genet84, 131-136. PubMed  Europe PubMed  R
2004
38. [YEAR:10-9-2004]Caldwell,R.A., Boucher,R.C. and Stutts,M.J.
    Serine protease activation of near-silent epithelial Na+ channels
    Am J Physiol Cell Physiol286, C190-C194. PubMed  Europe PubMed DOI
2003
39. Szabo,R., Wu,Q., Dickson,R.B., Netzel-Arnett,S., Antalis,T.M. and Bugge,T.H.
    Type II transmembrane serine proteases
    Thromb Haemost90, 185-193. PubMed  Europe PubMed DOI  V
2002
40. Vuagniaux,G., Vallet,V., Jaeger,N.F., Hummler,E. and Rossier,B.C.
    Synergistic activation of ENaC by three membrane-bound channel-activating serine proteases (mCAP1, mCAP2, and mCAP3) and serum- and glucocorticoid-regulated kinase (Sgk1) in Xenopus oocytes
    J Gen Physiol120, 191-201. PubMed  Europe PubMed DOI
2000
41. [YEAR:15-5-2000]Wallrapp,C., Hahnel,S., Muller-Pillasch,F., Burghardt,B., Iwamura,T., Ruthenburger,M., Lerch,M.M., Adler,G. and Gress,T.M.
    A novel transmembrane serine protease (TMPRSS3) overexpressed in pancreatic cancer
    Cancer Res60, 2602-2606. PubMed  Europe PubMed