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Literature for peptidase M28.010: glutamate carboxypeptidase II

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: A Assay, S Structure, T Target, P Specificity, K Knockout, E Expression, V Review, M Mutation, R Splicing, I Inhibitor, L Localization, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Butakova,N.S., Uspenskaia,A.A., Zyk,N.Y., Petrov,S.A., Popovicheva,K.A., Lunev,A.S., Petrosova,K.A., Mitrofanov,I.A., Ivashkovskaya,M.N., Evteev,S.A., Ivanenkov,Y.A., Beloglazkina,E.K., Larenkov,A.A. and Machulkin,A.E.<br>A series of conjugates based on prostate-specific membrane antigen ligands with the chelating agent DOTA: synthesis, radiolabeling, and biological activity<br>Eur J Med Chem (2026) 303, 118433-118433. PubMed  Europe PubMed DOI
  2. Sinha,A., Pandya,D.N., Eeka,P., Boyacioglu,O., Gmeiner,W.H. and Wadas,T.J.<br>Preclinical Evaluation of a Radiolabeled Anti-PSMA Dimeric Aptamer in a Murine Model of Human Prostate Cancer<br>Molecules (2026) 31 PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2025
  3. Cao,J., Sun,Z., Zhou,Z., Huang,Y., Peng,D., Jiang,X. and Chen,Y.<br>Preliminary clinical study of p-iodo benzoyl moiety-modified PSMA inhibitors and prospective comparison with 68Ga-PSMA-11<br>Sci Rep (2025) 15, 20000-20000. PubMed  Europe PubMed DOI  PMC  EPMC  I
  4. Das,G., Ptacek,J., Campbell,J., Li,X., Havlinova,B., Noonepalle,S.K., Villagra,A., Barinka,C. and Novakova,Z.<br>Targeting prostate cancer by new bispecific monocyte engager directed to prostate-specific membrane antigen<br>PLoS ONE (2025) 20, e0307353-e0307353. PubMed  Europe PubMed DOI  PMC  EPMC
  5. Kozikowski,A.P. and Neale,J.<br>How a Medicinal Chemistry Project Changed the Way Prostate Cancer is Diagnosed and Treated<br>J Med Chem (2025) 68, 20972-20978. PubMed  Europe PubMed DOI
  6. Li,W., Luo,Y., Hua,Y., Shen,Q., Chen,L., Xu,Y., Fu,H. and Yu,C.<br>Preclinical Evaluation of a Novel PSMA-Targeted Agent (68)Ga-NOTA-GC-PSMA for Prostate Cancer Imaging<br>Tomography (2025) 11 PubMed  Europe PubMed DOI  PMC  EPMC
  7. Liolios,C., Laros,G., Georgiou,K. and Kolokouris,A.<br>Prodrugs Targeting Prostate-Specific Membrane Antigen against Prostate Cancer<br>J Med Chem (2025) 68, 12296-12330. PubMed  Europe PubMed DOI
  8. Meng,X., Hu,X., Gao,S., Jia,W., Zhang,S., Zhang,S., Wang,X., Ma,S. and Qin,C.<br>PSMA-Guided PROTAC Degraders for Tumor-Specific Protein Degradation in Prostate Cancer<br>J Med Chem (2025) PubMed  Europe PubMed DOI
  9. Mesbahi,N., Yoon,H., Fulton,M.D. and Berkman,C.E.<br>A small-molecule pretargeting approach for PSMA-targeted conjugates<br>Bioorg Med Chem Lett (2025) 122, 130213-130213. PubMed  Europe PubMed DOI
  10. Neagu,M., Constantin,C., Hinescu,M.E., Bleotu,P.G., Popovici,M.G., Zai,M.I. and Spohr,K.M.<br>Radionuclides Landscape in Prostate Cancer Theranostics<br>Int J Mol Sci (2025) 26 PubMed  Europe PubMed DOI  PMC  EPMC
  11. Ninatti,G., Scilipoti,P., Pini,C., Barletta,F., Longoni,M., Gelardi,F., Sollini,M., Gandaglia,G., Sathekge,M., Montorsi,F., Chiti,A. and Briganti,A.<br>Time for action: actinium-225 PSMA-targeted alpha therapy for metastatic prostate cancer - a systematic review and meta-analysis<br>Theranostics (2025) 15, 3386-3399. PubMed  Europe PubMed DOI  PMC  EPMC
  12. Simpson,G.G., Quintana,J.M., Carrothers,J.E., Jiang,F., Walker,S.A., Cho,C., Weissleder,R., Miller,M.A. and Ng,T.S.C.<br>Fluorescent PSMA-Targeted Radiotheranostic Compounds for Multiscale Imaging<br>Bioconjug Chem (2025) 36, 1448-1460. PubMed  Europe PubMed DOI
  13. Talebian,H., Ait-Mohand,S., Ignatius Arokia Doss,P.M., Sanche,L. and Guerin,B.<br>Development and In Vitro Evaluation of [(64)Cu]Cu-NOTA-TP-PSMA, a Novel Radiotheranostic Agent Against Prostate Cancer<br>Int J Mol Sci (2025) 26 PubMed  Europe PubMed DOI  PMC  EPMC
  14. Ulaner,G.A., Bassett,J.C., Reddy,R., Thomsen,B., Reynolds,D., Jerjian,K.J., Wolfe,R., Benjamin,D.J., Fani,M., O'Donoghue,J., Baier,M., Schubert,N., Pais,B., De Rose,F. and Jaafar,L.<br>(61)Cu-NODAGA Prostate-specific Membrane Antigen Imaging and Therapy for Prostate Cancer: Phase 1 Trial of a New Class of (61)Cu-labeled PET Radiotracers<br>Radiology (2025) 317, e251151-e251151. PubMed  Europe PubMed DOI
  15. Wang,Y., Hu,M., Wu,J., Pan,L., Zhou,H., Li,L., Kuang,W., Xie,Y. and Chen,W.<br>Discovery of Novel KuE PSMA PET Tracers through Structure Fine-Tuning and Direct Photocatalyzed (18)F-Deoxyfluorination<br>J Med Chem (2025) 68, 14594-14608. PubMed  Europe PubMed DOI
  16. Zhang,X., Ma,L., Cai,K., Guo,X., Zhang,G., Dong,J., Zheng,Y., Su,X., Tao,T., Li,X. and Yuan,Y.<br>PSMA-Targeted Intracellular Self-Assembled Probe for Enhanced PET Imaging<br>Bioconjug Chem (2025) 36, 20-24. PubMed  Europe PubMed DOI
    17. 2024
  17. Abdulmajeed,A.Z. and Nazhan,W.<br>Kinetic Properties of Glutamate Carboxypeptidase II Partially Purified from Leukodystrophy Patient's Serum<br>ACS Chem Neurosci (2024) 15, 3384-3390. PubMed  Europe PubMed DOI
  18. Adekiya,T.A., Hudson,T., Bakare,O., Ameyaw,E.E., Adebayo,A., Olajubutu,O. and Adesina,S.K.<br>PSMA-targeted combination brusatol and docetaxel nanotherapeutics for the treatment of prostate cancer<br>Biomed Pharmacother (2024) 177, 117125-117125. PubMed  Europe PubMed DOI
  19. Dai,R., Cai,Z., Hu,R., Huang,Y., Fu,L., Yang,J., Hu,K. and Li,H.<br>(177)Lu-Labeled Bivalent Ligands of Prostate-Specific Membrane Antigen for Endoradiotherapy of Prostate Cancer<br>Mol Pharm (2024) 21, 883-894. PubMed  Europe PubMed DOI
  20. Dhull,A., Wei,J., Pulukuri,A.J., Rani,A., Sharma,R., Mesbahi,N., Yoon,H., Savoy,E.A., Xaivong Vi,S., Goody,K.J., Berkman,C.E., Wu,B.J. and Sharma,A.<br>PSMA-targeted dendrimer as an efficient anticancer drug delivery vehicle for prostate cancer<br>Nanoscale (2024) 16, 5634-5652. PubMed  Europe PubMed DOI
  21. Hoxie,N., Qiu,Y., Kales,S.C., Schneider,R., Hu,X., Dalal,A., Ford-Scheimer,S.L., Wiseman,R., Tsukamoto,T., Wei,H., Slusher,B.S., Janiszewski,J.S. and Hall,M.D.<br>Development of a high-throughput dual-stream liquid chromatography-tandem mass spectrometry method to screen for inhibitors of glutamate carboxypeptidase II<br>Rapid Commun Mass Spectrom (2024) , e9772-e9772. PubMed  Europe PubMed DOI  V
  22. Ismuha,R.R., Ritawidya,R., Daruwati,I. and Muchtaridi,M.<br>Future Prospect of Low-Molecular-Weight Prostate-Specific Membrane Antigen Radioisotopes Labeled as Theranostic Agents for Metastatic Castration-Resistant Prostate Cancer<br>Molecules (2024) 29 PubMed  Europe PubMed DOI  PMC  EPMC  V
  23. Jiang,Z., Kadeerhan,G., Zhang,J., Guo,W., Guo,H. and Wang,D.<br>Advances in prostate-specific membrane antigen-targeted theranostics: from radionuclides to near-infrared fluorescence technology<br>Front Immunol (2024) 15, 1533532-1533532. PubMed  Europe PubMed DOI  PMC  EPMC  V
  24. Maes,J., Gesquiere,S., De Spiegeleer,A., Maes,A. and Van de Wiele,C.<br>Prostate-Specific Membrane Antigen Biology and Pathophysiology in Prostate Carcinoma, an Update: Potential Implications for Targeted Imaging and Therapy<br>Int J Mol Sci (2024) 25 PubMed  Europe PubMed DOI  PMC  EPMC  V
  25. Oldan,J.D., Almaguel,F., Voter,A.F., Duran,A., Gafita,A., Pomper,M.G., Hope,T.A. and Rowe,S.P.<br>PSMA-Targeted Radiopharmaceuticals for Prostate Cancer Diagnosis and Therapy<br>Cancer J (2024) 30, 176-184. PubMed  Europe PubMed DOI
  26. Ouyang,M., Jia,M., Chang,Z., Wang,Y., Wang,K., Gao,X. and Tang,B.<br>Precise prostate cancer diagnosis using fluorescent nanoprobes for detecting PSA and PSMA in serum<br>Chem Commun (Camb) (2024) 60, 5181-5184. PubMed  Europe PubMed DOI
  27. Peters,D.E.<br>Targeting glutamate carboxypeptidase II in IBD<br>Adv Pharmacol (2024) 101, 265-285. PubMed  Europe PubMed DOI  V
  28. Savoy,E.A., Olatunji,F.P., Mesbahi,N., Ballard,R.K., Lovingier,C.L., Hendricksen,A.T., Fulton,M.D. and Berkman,C.E.<br>PSMA-targeted SMART molecules outfitted with SN38<br>Bioorg Med Chem Lett (2024) 101, 129657-129657. PubMed  Europe PubMed DOI
  29. Shirke,A.A., Walker,E., Chavali,S., Ramamurthy,G., Zhang,L., Panigrahi,A., Basilion,J.P. and Wang,X.<br>A Synergistic Strategy Combining Chemotherapy and Photodynamic Therapy to Eradicate Prostate Cancer<br>Int J Mol Sci (2024) 25 PubMed  Europe PubMed DOI  PMC  EPMC
  30. Waibel,S., Graf,N., Storz,J., Schultze-Seemann,S., Lauw,S., Gratzke,C., Bruckner,R., Wolf,P. and Wolf,I.<br>Photoimmunotherapy of Prostate Cancer With Antibody and Fab Fragments Targeting the Prostate Specific Membrane Antigen<br>Anticancer Res (2024) 44, 2343-2348. PubMed  Europe PubMed DOI
  31. Wang,Z., Zhu,B., Jiang,F., Chen,X., Wang,G., Ding,N., Song,S., Xu,X. and Zhang,W.<br>Design, synthesis and evaluation of novel prostate-specific membrane antigen-targeted aryl [(18)F]fluorosulfate PET tracers<br>Bioorg Med Chem (2024) 106, 117753-117753. PubMed  Europe PubMed DOI
  32. Yoon,H., Savoy,E.A., Mesbahi,N., Hendricksen,A.T., March,G.L., Fulton,M.D., Backer,B.S. and Berkman,C.E.<br>A PSMA-targeted doxorubicin small-molecule drug conjugate<br>Bioorg Med Chem Lett (2024) 104, 129712-129712. PubMed  Europe PubMed DOI
    33. 2023
  33. Eltit,F., Robinson,N., Yu,P.L.I., Pandey,M., Lozada,J., Guo,Y., Sharma,M., Ozturan,D., Ganier,L., Belanger,E., Lack,N.A., Perrin,D.M., Cox,M.E. and Goldenberg,S.L.<br>The "Ins and Outs" of Prostate Specific Membrane Antigen (PSMA) as Specific Target in Prostate Cancer Therapy<br>Adv Exp Med Biol (2023) 1408, 291-308. PubMed  Europe PubMed DOI
  34. Hasnowo,L.A., Larkina,M.S., Plotnikov,E., Bodenko,V., Yuldasheva,F., Stasyuk,E., Petrov,S.A., Zyk,N.Y., Machulkin,A.E., Vorozhtsov,N.I., Beloglazkina,E.K., Nenajdenko,V.G., Tolmachev,V., Orlova,A., Majouga,A.G. and Yusubov,M.S.<br>Synthesis, (123)I-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with a Tributylstannyl Prosthetic Group in Their Structures<br>Int J Mol Sci (2023) 24 PubMed  Europe PubMed DOI  PMC  EPMC
  35. Lee,Z., Heston,W.D., Wang,X. and Basilion,J.P.<br>GCP III is not the "off-target" for urea-based PSMA ligands<br>Eur J Nucl Med Mol Imaging (2023) 50, 2944-2946. PubMed  Europe PubMed DOI  PMC  EPMC
  36. Notohamiprodjo,S., Eiber,M., Lohrmann,C. and Weber,W.A.<br>Reply: PSMA Is Not Specific to Prostate Cancer<br>J Nucl Med (2023) 64, 1326-1327. PubMed  Europe PubMed DOI
  37. Peters,D.E., Norris,L.D., Tenora,L., Snajdr,I., Ponti,A.K., Zhu,X., Sakamoto,S., Veeravalli,V., Pradhan,M., Alt,J., Thomas,A.G., Majer,P., Rais,R., McDonald,C. and Slusher,B.S.<br>A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis<br>Sci Transl Med (2023) 15, eabn7491-eabn7491. PubMed  Europe PubMed DOI  I
  38. Song,B. and Hong,S.K.<br>The era of prostate-specific membrane antigen for the diagnosis and treatment of prostate cancer: A novel horizon<br>Investig Clin Urol (2023) 64, 197-199. PubMed  Europe PubMed DOI  PMC  EPMC
  39. Strauss,A.S., Bolenz,C., Beer,A.J., Zengerling,F., Beer,M. and Miksch,J.<br>[Opportunities for prostate-specific membrane antigen hybrid imaging in prostate cancer]<br>Urologie (2023) 62, 1153-1159. PubMed  Europe PubMed DOI  V
  40. Sui,Y., Duan,X., Zhang,J., Chu,Y. and Yang,X.<br>Synthesis and characterization of a novel (68)Ga-labeled p-bromobenzyl lysine-urea-ODAP PSMA inhibitor<br>Bioorg Med Chem Lett (2023) 91, 129382-129382. PubMed  Europe PubMed DOI  I
  41. Thomsen,M.B., Landau,A.M., Bender,D. and Cumming,P.<br>Autoradiographic characterization of [(18) F]PSMA-1007 binding in rat brain<br>Synapse (2023) 77, e22280-e22280. PubMed  Europe PubMed DOI
  42. Wang,X., Chen,Y., Xiong,Y., Zhang,L., Wang,B., Liu,Y. and Cui,M.<br>Design and Characterization of Squaramic Acid-Based Prostate-Specific Membrane Antigen Inhibitors for Prostate Cancer<br>J Med Chem (2023) 66, 6889-6904. PubMed  Europe PubMed DOI  I
  43. Yang,X., Nao,S.C., Lin,C., Kong,L., Wang,J., Ko,C.N., Liu,J., Ma,D.L., Leung,C.H. and Wang,W.<br>A cell-impermeable luminogenic probe for near-infrared imaging of prostate-specific membrane antigen in prostate cancer microenvironments<br>Eur J Med Chem (2023) 259, 115659-115659. PubMed  Europe PubMed DOI
  44. Zhang,L., Shi,X., Li,Y., Duan,X., Yang,X., Hu,Z. and Cui,M.<br>An NIR-II Probe with High PSMA Affinity Demonstrates an Unexpected Excellent Bone Imaging Ability<br>J Med Chem (2023) 66, 16441-16454. PubMed  Europe PubMed DOI
  45. Zyk,N.Y., Garanina,A.S., Plotnikova,E.A., Ber,A.P., Nimenko,E.A., Dashkova,N.S., Uspenskaia,A.A., Shafikov,R.R., Skvortsov,D.A., Petrov,S.A., Pankratov,A.A., Zyk,N.V., Majouga,A.G., Beloglazkina,E.K. and Machulkin,A.E.<br>Synthesis of Prostate-Specific Membrane Antigen-Targeted Bimodal Conjugates of Cytotoxic Agents and Antiandrogens and Their Comparative Assessment with Monoconjugates<br>Int J Mol Sci (2023) 24 PubMed  Europe PubMed DOI  PMC  EPMC
    46. 2022
  46. Bim,D., Navratil,M., Gutten,O., Konvalinka,J., Kutil,Z., Culka,M., Navratil,V., Alexandrova,A.N., Barinka,C. and Rulisek,L.<br>Predicting Effects of Site-Directed Mutagenesis on Enzyme Kinetics by QM/MM and QM Calculations: A Case of Glutamate Carboxypeptidase II<br>J Phys Chem B (2022) 126, 132-143. PubMed  Europe PubMed DOI
  47. Boinapally,S., Lisok,A., Lofland,G., Minn,I., Yan,Y., Jiang,Z., Shin,M.J., Merino,V.F., Zheng,L., Brayton,C., Pomper,M.G. and Banerjee,S.R.<br>Hetero-bivalent agents targeting FAP and PSMA<br>Eur J Nucl Med Mol Imaging (2022) 49, 4369-4381. PubMed  Europe PubMed DOI
  48. Chen,Y., Minn,I., Rowe,S.P., Lisok,A., Chatterjee,S., Brummet,M., Banerjee,S.R., Mease,R.C. and Pomper,M.G.<br>A Series of PSMA-Targeted Near-Infrared Fluorescent Imaging Agents<br>Biomolecules (2022) 12 PubMed  Europe PubMed DOI  PMC  EPMC
  49. Hadi,M., Akbari,A., Dehbidi,G.R., Arabsolghar,R. and Bahmani,T.<br>Expression and Purification of Human Granzyme B Fusion Protein to Induce Targeted Apoptosis in PSMA Positive Prostate Cancer Cells<br>Protein Pept Lett (2022) 29, 631-640. PubMed  Europe PubMed DOI
  50. Hawkey,N.M., Sartor,A.O., Morris,M.J. and Armstrong,A.J.<br>Prostate-specific membrane antigen-targeted theranostics: past, present, and future approaches<br>Clin Adv Hematol Oncol (2022) 20, 227-238. PubMed  Europe PubMed  V
  51. Hirata,S., Mishiro,K., Higashi,T., Fuchigami,T., Munekane,M., Arano,Y., Kinuya,S. and Ogawa,K.<br>Synthesis and evaluation of a multifunctional probe with a high affinity for prostate-specific membrane antigen (PSMA) and bone<br>Nucl Med Biol (2022) 114-115, 34-41. PubMed  Europe PubMed DOI
  52. Hong,X., Mao,L., Xu,L., Hu,Q. and Jia,R.<br>Prostate-specific membrane antigen modulates the progression of prostate cancer by regulating the synthesis of arginine and proline and the expression of androgen receptors and Fos proto-oncogenes<br>Bioengineered (2022) 13, 995-1012. PubMed  Europe PubMed DOI  PMC  EPMC  K
  53. Imperio,D., Grolla,A.A., Moro,M., Bortolotto,V., Del Grosso,E., Genazzani,A.A. and Panza,L.<br>Functionalization of beta-cyclodextrin with a urea-based PSMA ligand and preliminary studies on targeting prostate cancer cells<br>Bioorg Med Chem Lett (2022) 73, 128890-128890. PubMed  Europe PubMed DOI
  54. Jia,A.Y., Kashani,R., Zaorsky,N.G., Baumann,B.C., Michalski,J., Zoberi,J.E., Kiess,A.P. and Spratt,D.E.<br>Lutetium-177 Prostate-Specific Membrane Antigen Therapy: A Practical Review<br>Pract Radiat Oncol (2022) 12, 294-299. PubMed  Europe PubMed DOI  V
  55. Kondo,Y., Kimura,H., Sasaki,I., Watanabe,S., Ohshima,Y., Yagi,Y., Hattori,Y., Koda,M., Kawashima,H., Yasui,H. and Ishioka,N.S.<br>Copper-mediated radioiodination and radiobromination via aryl boronic precursor and its application to (125)I/(77)Br-labeled prostate-specific membrane antigen imaging probes<br>Bioorg Med Chem (2022) 69, 116915-116915. PubMed  Europe PubMed DOI
  56. Li,Y., Duan,X., Xu,H., Zhang,J., Zhou,H., Zhang,X., Zhang,J., Yang,Z., Hu,Z., Zhang,N., Tian,J. and Yang,X.<br>Optimization of ODAP-Urea-based dual-modality PSMA targeting probes for sequential PET-CT and optical imaging<br>Bioorg Med Chem (2022) 66, 116810-116810. PubMed  Europe PubMed DOI
  57. Madan,R.A., Mena,E., Lindenberg,L. and Choyke,P.L.<br>With New Technology Comes Great Responsibility: Prostate-Specific Membrane Antigen Imaging in Recurrent Prostate Cancer<br>J Clin Oncol (2022) 40, 3015-3019. PubMed  Europe PubMed DOI
  58. Olatunji,F.P., Pun,M., Herman,J.W., Romero,O., Maniatopoulos,M., Latoche,J.D., Parise,R.A., Guo,J., Beumer,J.H., Anderson,C.J. and Berkman,C.E.<br>Modular Smart Molecules for PSMA-Targeted Chemotherapy<br>Mol Cancer Ther (2022) 21, 1701-1709. PubMed  Europe PubMed DOI
  59. Yang,J.U., Kim,S., Ahn,J.H., Kim,M.H., Kil,H.S., Chi,D.Y., Lee,K.C., Lee,Y.J. and Park,J.A.<br>Feasibility of Gd-Based prostate cancer targeted magnetic resonance agents using prostate specific membrane antigen<br>Biochem Biophys Res Commun (2022) 607, 152-157. PubMed  Europe PubMed DOI
  60. Yuan,W., Liu,B., Sanda,M., Wei,R., Benicky,J., Novakova,Z., Barinka,C. and Goldman,R.<br>Glycoforms of human prostate-specific membrane antigen (PSMA) in human cells and prostate tissue<br>Prostate (2022) 82, 132-144. PubMed  Europe PubMed DOI
  61. Zha,Z., Choi,S.R., Li,L., Zhao,R., Ploessl,K., Yao,X., Alexoff,D., Zhu,L. and Kung,H.F.<br>New PSMA-Targeting Ligands: Transformation from Diagnosis (Ga-68) to Radionuclide Therapy (Lu-177)<br>J Med Chem (2022) 65, 13001-13012. PubMed  Europe PubMed DOI
  62. Zhang,X., Chen,K., Jiang,K., He,J., An,Y., He,Z. and Sun,F.<br>[Prokaryotic expression of prostate-specific membrane antigen (PSMA) nanoantibody gene and screening of natural phage nanoantibody library]<br>Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2022) 38, 1030-1035. PubMed  Europe PubMed
  63. Zyk,N.Y., Ber,A.P., Nimenko,E.A., Shafikov,R.R., Evteev,S.A., Petrov,S.A., Uspenskaya,A.A., Dashkova,N.S., Ivanenkov,Y.A., Skvortsov,D.A., Beloglazkina,E.K., Majouga,A.G. and Machulkin,A.E.<br>Synthesis and initial in vitro evaluation of PSMA-targeting ligands with a modified aromatic moiety at the lysine epsilon-nitrogen atom<br>Bioorg Med Chem Lett (2022) 71, 128840-128840. PubMed  Europe PubMed DOI
    64. 2021
  64. Frontera,A. and Bauza,A.<br>Glutamate carboxypeptidase II as a model system for designing host-guest units: a theoretical approach<br>Org Biomol Chem (2021) 19, 7816-7821. PubMed  Europe PubMed DOI
  65. Plichta,K.A., Graves,S.A. and Buatti,J.M.<br>Prostate-Specific Membrane Antigen (PSMA) Theranostics for Treatment of Oligometastatic Prostate Cancer<br>Int J Mol Sci (2021) 22 PubMed  Europe PubMed DOI  PMC  EPMC
  66. Zhang,L., Shi,X., Li,Y., Duan,X., Zhang,Z., Fu,H., Yang,X., Tian,J., Hu,Z. and Cui,M.<br>Visualizing Tumors in Real Time: A Highly Sensitive PSMA Probe for NIR-II Imaging and Intraoperative Tumor Resection<br>J Med Chem (2021) 64, 7735-7745. PubMed  Europe PubMed DOI
    67. 2020
  67. Abecassis,J.P., Ghazzar,N., Peyromaure,M. and Giraud,P.<br>Prostate imaging: Contribution of PET PSMA and MRI<br>Cancer Radiother (2020) 24, 423-428. PubMed  Europe PubMed DOI
  68. Vornov,J.J., Peters,D., Nedelcovych,M., Hollinger,K., Rais,R. and Slusher,B.S.<br>Looking for drugs in all the wrong places: use of GCPII inhibitors outside the brain<br>Neurochem Res (2020) 45, 1256-1267. PubMed  Europe PubMed DOI
    69. 2019
  69. Barinka,C., Novakova,Z., Hin,N., Bim,D., Ferraris,D.V., Duvall,B., Kabarriti,G., Tsukamoto,R., Budesinsky,M., Motlova,L., Rojas,C., Slusher,B.S., Rokob,T.A., Rulisek,L. and Tsukamoto,T.<br>Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors<br>Bioorg Med Chem (2019) 27, 255-264. PubMed  Europe PubMed DOI  I
  70. Neale,J.H. and Yamamoto,T.<br>N-acetylaspartylglutamate (NAAG) and glutamate carboxypeptidase II: an abundant peptide neurotransmitter-enzyme system with multiple clinical applications<br>Prog Neurobiol (2019) , 101722-101722. PubMed  Europe PubMed DOI
    71. 2018
  71. Choi,J.Y., Ko,J.H. and Jo,S.A.<br>HDAC1 regulates the stability of glutamate carboxypeptidase II protein by modulating acetylation status of lysine 479 residue<br>Biochem Biophys Res Commun (2018) 497, 416-423. PubMed  Europe PubMed DOI
  72. Endepols,H., Mottaghy,F.M., Simsekyilmaz,S., Bucerius,J., Vogt,F., Winz,O., Richarz,R., Krapf,P., Neumaier,B., Zlatopolskiy,B.D. and Morgenroth,A.<br>In vivo molecular imaging of glutamate carboxypeptidase II expression in re-endothelialisation after percutaneous balloon denudation in a rat model<br>Sci Rep (2018) 8, 7411-7411. PubMed  Europe PubMed DOI  PMC  EPMC  L
  73. Ptacek,J., Nedvedova,J., Navratil,M., Havlinova,B., Konvalinka,J. and Barinka,C.<br>The calcium-binding site of human glutamate carboxypeptidase II is critical for dimerization, thermal stability, and enzymatic activity<br>Protein Sci (2018) 27, 1575-1584. PubMed  Europe PubMed DOI
  74. Wu,W., Xu,S., Wang,J., Zhang,K., Zhang,M., Cao,Y., Ren,H., Zheng,D. and Zhong,C.<br>Metabolite differences between glutamate carboxypeptidase II gene knockout mice and their wild-type littermates after traumatic brain injury: a 7-tesla (1)H-MRS study<br>BMC Neurosci (2018) 19, 75-75. PubMed  Europe PubMed DOI  PMC  EPMC  K  U
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