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Literature for peptidase M28.010: glutamate carboxypeptidase II

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: A Assay, S Structure, T Target, P Specificity, K Knockout, E Expression, V Review, M Mutation, R Splicing, I Inhibitor, L Localization, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Butakova,N.S., Uspenskaia,A.A., Zyk,N.Y., Petrov,S.A., Popovicheva,K.A., Lunev,A.S., Petrosova,K.A., Mitrofanov,I.A., Ivashkovskaya,M.N., Evteev,S.A., Ivanenkov,Y.A., Beloglazkina,E.K., Larenkov,A.A. and Machulkin,A.E.
    A series of conjugates based on prostate-specific membrane antigen ligands with the chelating agent DOTA: synthesis, radiolabeling, and biological activity
    Eur J Med Chem (2026) 303, 118433-118433. PubMed  Europe PubMed DOI
  2. Sinha,A., Pandya,D.N., Eeka,P., Boyacioglu,O., Gmeiner,W.H. and Wadas,T.J.
    Preclinical Evaluation of a Radiolabeled Anti-PSMA Dimeric Aptamer in a Murine Model of Human Prostate Cancer
    Molecules (2026) 31 PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2025
  3. Cao,J., Sun,Z., Zhou,Z., Huang,Y., Peng,D., Jiang,X. and Chen,Y.
    Preliminary clinical study of p-iodo benzoyl moiety-modified PSMA inhibitors and prospective comparison with 68Ga-PSMA-11
    Sci Rep (2025) 15, 20000-20000. PubMed  Europe PubMed DOI  PMC  EPMC  I
  4. Das,G., Ptacek,J., Campbell,J., Li,X., Havlinova,B., Noonepalle,S.K., Villagra,A., Barinka,C. and Novakova,Z.
    Targeting prostate cancer by new bispecific monocyte engager directed to prostate-specific membrane antigen
    PLoS ONE (2025) 20, e0307353-e0307353. PubMed  Europe PubMed DOI  PMC  EPMC
  5. Kozikowski,A.P. and Neale,J.
    How a Medicinal Chemistry Project Changed the Way Prostate Cancer is Diagnosed and Treated
    J Med Chem (2025) 68, 20972-20978. PubMed  Europe PubMed DOI
  6. Li,W., Luo,Y., Hua,Y., Shen,Q., Chen,L., Xu,Y., Fu,H. and Yu,C.
    Preclinical Evaluation of a Novel PSMA-Targeted Agent (68)Ga-NOTA-GC-PSMA for Prostate Cancer Imaging
    Tomography (2025) 11 PubMed  Europe PubMed DOI  PMC  EPMC
  7. Liolios,C., Laros,G., Georgiou,K. and Kolokouris,A.
    Prodrugs Targeting Prostate-Specific Membrane Antigen against Prostate Cancer
    J Med Chem (2025) 68, 12296-12330. PubMed  Europe PubMed DOI
  8. Meng,X., Hu,X., Gao,S., Jia,W., Zhang,S., Zhang,S., Wang,X., Ma,S. and Qin,C.
    PSMA-Guided PROTAC Degraders for Tumor-Specific Protein Degradation in Prostate Cancer
    J Med Chem (2025) PubMed  Europe PubMed DOI
  9. Mesbahi,N., Yoon,H., Fulton,M.D. and Berkman,C.E.
    A small-molecule pretargeting approach for PSMA-targeted conjugates
    Bioorg Med Chem Lett (2025) 122, 130213-130213. PubMed  Europe PubMed DOI
  10. Neagu,M., Constantin,C., Hinescu,M.E., Bleotu,P.G., Popovici,M.G., Zai,M.I. and Spohr,K.M.
    Radionuclides Landscape in Prostate Cancer Theranostics
    Int J Mol Sci (2025) 26 PubMed  Europe PubMed DOI  PMC  EPMC
  11. Ninatti,G., Scilipoti,P., Pini,C., Barletta,F., Longoni,M., Gelardi,F., Sollini,M., Gandaglia,G., Sathekge,M., Montorsi,F., Chiti,A. and Briganti,A.
    Time for action: actinium-225 PSMA-targeted alpha therapy for metastatic prostate cancer - a systematic review and meta-analysis
    Theranostics (2025) 15, 3386-3399. PubMed  Europe PubMed DOI  PMC  EPMC
  12. Simpson,G.G., Quintana,J.M., Carrothers,J.E., Jiang,F., Walker,S.A., Cho,C., Weissleder,R., Miller,M.A. and Ng,T.S.C.
    Fluorescent PSMA-Targeted Radiotheranostic Compounds for Multiscale Imaging
    Bioconjug Chem (2025) 36, 1448-1460. PubMed  Europe PubMed DOI
  13. Talebian,H., Ait-Mohand,S., Ignatius Arokia Doss,P.M., Sanche,L. and Guerin,B.
    Development and In Vitro Evaluation of [(64)Cu]Cu-NOTA-TP-PSMA, a Novel Radiotheranostic Agent Against Prostate Cancer
    Int J Mol Sci (2025) 26 PubMed  Europe PubMed DOI  PMC  EPMC
  14. Ulaner,G.A., Bassett,J.C., Reddy,R., Thomsen,B., Reynolds,D., Jerjian,K.J., Wolfe,R., Benjamin,D.J., Fani,M., O'Donoghue,J., Baier,M., Schubert,N., Pais,B., De Rose,F. and Jaafar,L.
    (61)Cu-NODAGA Prostate-specific Membrane Antigen Imaging and Therapy for Prostate Cancer: Phase 1 Trial of a New Class of (61)Cu-labeled PET Radiotracers
    Radiology (2025) 317, e251151-e251151. PubMed  Europe PubMed DOI
  15. Wang,Y., Hu,M., Wu,J., Pan,L., Zhou,H., Li,L., Kuang,W., Xie,Y. and Chen,W.
    Discovery of Novel KuE PSMA PET Tracers through Structure Fine-Tuning and Direct Photocatalyzed (18)F-Deoxyfluorination
    J Med Chem (2025) 68, 14594-14608. PubMed  Europe PubMed DOI
  16. Zhang,X., Ma,L., Cai,K., Guo,X., Zhang,G., Dong,J., Zheng,Y., Su,X., Tao,T., Li,X. and Yuan,Y.
    PSMA-Targeted Intracellular Self-Assembled Probe for Enhanced PET Imaging
    Bioconjug Chem (2025) 36, 20-24. PubMed  Europe PubMed DOI
    17. 2024
  17. Abdulmajeed,A.Z. and Nazhan,W.
    Kinetic Properties of Glutamate Carboxypeptidase II Partially Purified from Leukodystrophy Patient's Serum
    ACS Chem Neurosci (2024) 15, 3384-3390. PubMed  Europe PubMed DOI
  18. Adekiya,T.A., Hudson,T., Bakare,O., Ameyaw,E.E., Adebayo,A., Olajubutu,O. and Adesina,S.K.
    PSMA-targeted combination brusatol and docetaxel nanotherapeutics for the treatment of prostate cancer
    Biomed Pharmacother (2024) 177, 117125-117125. PubMed  Europe PubMed DOI
  19. Dai,R., Cai,Z., Hu,R., Huang,Y., Fu,L., Yang,J., Hu,K. and Li,H.
    (177)Lu-Labeled Bivalent Ligands of Prostate-Specific Membrane Antigen for Endoradiotherapy of Prostate Cancer
    Mol Pharm (2024) 21, 883-894. PubMed  Europe PubMed DOI
  20. Dhull,A., Wei,J., Pulukuri,A.J., Rani,A., Sharma,R., Mesbahi,N., Yoon,H., Savoy,E.A., Xaivong Vi,S., Goody,K.J., Berkman,C.E., Wu,B.J. and Sharma,A.
    PSMA-targeted dendrimer as an efficient anticancer drug delivery vehicle for prostate cancer
    Nanoscale (2024) 16, 5634-5652. PubMed  Europe PubMed DOI
  21. Hoxie,N., Qiu,Y., Kales,S.C., Schneider,R., Hu,X., Dalal,A., Ford-Scheimer,S.L., Wiseman,R., Tsukamoto,T., Wei,H., Slusher,B.S., Janiszewski,J.S. and Hall,M.D.
    Development of a high-throughput dual-stream liquid chromatography-tandem mass spectrometry method to screen for inhibitors of glutamate carboxypeptidase II
    Rapid Commun Mass Spectrom (2024) , e9772-e9772. PubMed  Europe PubMed DOI  V
  22. Ismuha,R.R., Ritawidya,R., Daruwati,I. and Muchtaridi,M.
    Future Prospect of Low-Molecular-Weight Prostate-Specific Membrane Antigen Radioisotopes Labeled as Theranostic Agents for Metastatic Castration-Resistant Prostate Cancer
    Molecules (2024) 29 PubMed  Europe PubMed DOI  PMC  EPMC  V
  23. Jiang,Z., Kadeerhan,G., Zhang,J., Guo,W., Guo,H. and Wang,D.
    Advances in prostate-specific membrane antigen-targeted theranostics: from radionuclides to near-infrared fluorescence technology
    Front Immunol (2024) 15, 1533532-1533532. PubMed  Europe PubMed DOI  PMC  EPMC  V
  24. Maes,J., Gesquiere,S., De Spiegeleer,A., Maes,A. and Van de Wiele,C.
    Prostate-Specific Membrane Antigen Biology and Pathophysiology in Prostate Carcinoma, an Update: Potential Implications for Targeted Imaging and Therapy
    Int J Mol Sci (2024) 25 PubMed  Europe PubMed DOI  PMC  EPMC  V
  25. Oldan,J.D., Almaguel,F., Voter,A.F., Duran,A., Gafita,A., Pomper,M.G., Hope,T.A. and Rowe,S.P.
    PSMA-Targeted Radiopharmaceuticals for Prostate Cancer Diagnosis and Therapy
    Cancer J (2024) 30, 176-184. PubMed  Europe PubMed DOI
  26. Ouyang,M., Jia,M., Chang,Z., Wang,Y., Wang,K., Gao,X. and Tang,B.
    Precise prostate cancer diagnosis using fluorescent nanoprobes for detecting PSA and PSMA in serum
    Chem Commun (Camb) (2024) 60, 5181-5184. PubMed  Europe PubMed DOI
  27. Peters,D.E.
    Targeting glutamate carboxypeptidase II in IBD
    Adv Pharmacol (2024) 101, 265-285. PubMed  Europe PubMed DOI  V
  28. Savoy,E.A., Olatunji,F.P., Mesbahi,N., Ballard,R.K., Lovingier,C.L., Hendricksen,A.T., Fulton,M.D. and Berkman,C.E.
    PSMA-targeted SMART molecules outfitted with SN38
    Bioorg Med Chem Lett (2024) 101, 129657-129657. PubMed  Europe PubMed DOI
  29. Shirke,A.A., Walker,E., Chavali,S., Ramamurthy,G., Zhang,L., Panigrahi,A., Basilion,J.P. and Wang,X.
    A Synergistic Strategy Combining Chemotherapy and Photodynamic Therapy to Eradicate Prostate Cancer
    Int J Mol Sci (2024) 25 PubMed  Europe PubMed DOI  PMC  EPMC
  30. Waibel,S., Graf,N., Storz,J., Schultze-Seemann,S., Lauw,S., Gratzke,C., Bruckner,R., Wolf,P. and Wolf,I.
    Photoimmunotherapy of Prostate Cancer With Antibody and Fab Fragments Targeting the Prostate Specific Membrane Antigen
    Anticancer Res (2024) 44, 2343-2348. PubMed  Europe PubMed DOI
  31. Wang,Z., Zhu,B., Jiang,F., Chen,X., Wang,G., Ding,N., Song,S., Xu,X. and Zhang,W.
    Design, synthesis and evaluation of novel prostate-specific membrane antigen-targeted aryl [(18)F]fluorosulfate PET tracers
    Bioorg Med Chem (2024) 106, 117753-117753. PubMed  Europe PubMed DOI
  32. Yoon,H., Savoy,E.A., Mesbahi,N., Hendricksen,A.T., March,G.L., Fulton,M.D., Backer,B.S. and Berkman,C.E.
    A PSMA-targeted doxorubicin small-molecule drug conjugate
    Bioorg Med Chem Lett (2024) 104, 129712-129712. PubMed  Europe PubMed DOI
    33. 2023
  33. Eltit,F., Robinson,N., Yu,P.L.I., Pandey,M., Lozada,J., Guo,Y., Sharma,M., Ozturan,D., Ganier,L., Belanger,E., Lack,N.A., Perrin,D.M., Cox,M.E. and Goldenberg,S.L.
    The "Ins and Outs" of Prostate Specific Membrane Antigen (PSMA) as Specific Target in Prostate Cancer Therapy
    Adv Exp Med Biol (2023) 1408, 291-308. PubMed  Europe PubMed DOI
  34. Hasnowo,L.A., Larkina,M.S., Plotnikov,E., Bodenko,V., Yuldasheva,F., Stasyuk,E., Petrov,S.A., Zyk,N.Y., Machulkin,A.E., Vorozhtsov,N.I., Beloglazkina,E.K., Nenajdenko,V.G., Tolmachev,V., Orlova,A., Majouga,A.G. and Yusubov,M.S.
    Synthesis, (123)I-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with a Tributylstannyl Prosthetic Group in Their Structures
    Int J Mol Sci (2023) 24 PubMed  Europe PubMed DOI  PMC  EPMC
  35. Lee,Z., Heston,W.D., Wang,X. and Basilion,J.P.
    GCP III is not the "off-target" for urea-based PSMA ligands
    Eur J Nucl Med Mol Imaging (2023) 50, 2944-2946. PubMed  Europe PubMed DOI  PMC  EPMC
  36. Notohamiprodjo,S., Eiber,M., Lohrmann,C. and Weber,W.A.
    Reply: PSMA Is Not Specific to Prostate Cancer
    J Nucl Med (2023) 64, 1326-1327. PubMed  Europe PubMed DOI
  37. Peters,D.E., Norris,L.D., Tenora,L., Snajdr,I., Ponti,A.K., Zhu,X., Sakamoto,S., Veeravalli,V., Pradhan,M., Alt,J., Thomas,A.G., Majer,P., Rais,R., McDonald,C. and Slusher,B.S.
    A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis
    Sci Transl Med (2023) 15, eabn7491-eabn7491. PubMed  Europe PubMed DOI  I
  38. Song,B. and Hong,S.K.
    The era of prostate-specific membrane antigen for the diagnosis and treatment of prostate cancer: A novel horizon
    Investig Clin Urol (2023) 64, 197-199. PubMed  Europe PubMed DOI  PMC  EPMC
  39. Strauss,A.S., Bolenz,C., Beer,A.J., Zengerling,F., Beer,M. and Miksch,J.
    [Opportunities for prostate-specific membrane antigen hybrid imaging in prostate cancer]
    Urologie (2023) 62, 1153-1159. PubMed  Europe PubMed DOI  V
  40. Sui,Y., Duan,X., Zhang,J., Chu,Y. and Yang,X.
    Synthesis and characterization of a novel (68)Ga-labeled p-bromobenzyl lysine-urea-ODAP PSMA inhibitor
    Bioorg Med Chem Lett (2023) 91, 129382-129382. PubMed  Europe PubMed DOI  I
  41. Thomsen,M.B., Landau,A.M., Bender,D. and Cumming,P.
    Autoradiographic characterization of [(18) F]PSMA-1007 binding in rat brain
    Synapse (2023) 77, e22280-e22280. PubMed  Europe PubMed DOI
  42. Wang,X., Chen,Y., Xiong,Y., Zhang,L., Wang,B., Liu,Y. and Cui,M.
    Design and Characterization of Squaramic Acid-Based Prostate-Specific Membrane Antigen Inhibitors for Prostate Cancer
    J Med Chem (2023) 66, 6889-6904. PubMed  Europe PubMed DOI  I
  43. Yang,X., Nao,S.C., Lin,C., Kong,L., Wang,J., Ko,C.N., Liu,J., Ma,D.L., Leung,C.H. and Wang,W.
    A cell-impermeable luminogenic probe for near-infrared imaging of prostate-specific membrane antigen in prostate cancer microenvironments
    Eur J Med Chem (2023) 259, 115659-115659. PubMed  Europe PubMed DOI
  44. Zhang,L., Shi,X., Li,Y., Duan,X., Yang,X., Hu,Z. and Cui,M.
    An NIR-II Probe with High PSMA Affinity Demonstrates an Unexpected Excellent Bone Imaging Ability
    J Med Chem (2023) 66, 16441-16454. PubMed  Europe PubMed DOI
  45. Zyk,N.Y., Garanina,A.S., Plotnikova,E.A., Ber,A.P., Nimenko,E.A., Dashkova,N.S., Uspenskaia,A.A., Shafikov,R.R., Skvortsov,D.A., Petrov,S.A., Pankratov,A.A., Zyk,N.V., Majouga,A.G., Beloglazkina,E.K. and Machulkin,A.E.
    Synthesis of Prostate-Specific Membrane Antigen-Targeted Bimodal Conjugates of Cytotoxic Agents and Antiandrogens and Their Comparative Assessment with Monoconjugates
    Int J Mol Sci (2023) 24 PubMed  Europe PubMed DOI  PMC  EPMC
    46. 2022
  46. Bim,D., Navratil,M., Gutten,O., Konvalinka,J., Kutil,Z., Culka,M., Navratil,V., Alexandrova,A.N., Barinka,C. and Rulisek,L.
    Predicting Effects of Site-Directed Mutagenesis on Enzyme Kinetics by QM/MM and QM Calculations: A Case of Glutamate Carboxypeptidase II
    J Phys Chem B (2022) 126, 132-143. PubMed  Europe PubMed DOI
  47. Boinapally,S., Lisok,A., Lofland,G., Minn,I., Yan,Y., Jiang,Z., Shin,M.J., Merino,V.F., Zheng,L., Brayton,C., Pomper,M.G. and Banerjee,S.R.
    Hetero-bivalent agents targeting FAP and PSMA
    Eur J Nucl Med Mol Imaging (2022) 49, 4369-4381. PubMed  Europe PubMed DOI
  48. Chen,Y., Minn,I., Rowe,S.P., Lisok,A., Chatterjee,S., Brummet,M., Banerjee,S.R., Mease,R.C. and Pomper,M.G.
    A Series of PSMA-Targeted Near-Infrared Fluorescent Imaging Agents
    Biomolecules (2022) 12 PubMed  Europe PubMed DOI  PMC  EPMC
  49. Hadi,M., Akbari,A., Dehbidi,G.R., Arabsolghar,R. and Bahmani,T.
    Expression and Purification of Human Granzyme B Fusion Protein to Induce Targeted Apoptosis in PSMA Positive Prostate Cancer Cells
    Protein Pept Lett (2022) 29, 631-640. PubMed  Europe PubMed DOI
  50. Hawkey,N.M., Sartor,A.O., Morris,M.J. and Armstrong,A.J.
    Prostate-specific membrane antigen-targeted theranostics: past, present, and future approaches
    Clin Adv Hematol Oncol (2022) 20, 227-238. PubMed  Europe PubMed  V
  51. Hirata,S., Mishiro,K., Higashi,T., Fuchigami,T., Munekane,M., Arano,Y., Kinuya,S. and Ogawa,K.
    Synthesis and evaluation of a multifunctional probe with a high affinity for prostate-specific membrane antigen (PSMA) and bone
    Nucl Med Biol (2022) 114-115, 34-41. PubMed  Europe PubMed DOI
  52. Hong,X., Mao,L., Xu,L., Hu,Q. and Jia,R.
    Prostate-specific membrane antigen modulates the progression of prostate cancer by regulating the synthesis of arginine and proline and the expression of androgen receptors and Fos proto-oncogenes
    Bioengineered (2022) 13, 995-1012. PubMed  Europe PubMed DOI  PMC  EPMC  K
  53. Imperio,D., Grolla,A.A., Moro,M., Bortolotto,V., Del Grosso,E., Genazzani,A.A. and Panza,L.
    Functionalization of beta-cyclodextrin with a urea-based PSMA ligand and preliminary studies on targeting prostate cancer cells
    Bioorg Med Chem Lett (2022) 73, 128890-128890. PubMed  Europe PubMed DOI
  54. Jia,A.Y., Kashani,R., Zaorsky,N.G., Baumann,B.C., Michalski,J., Zoberi,J.E., Kiess,A.P. and Spratt,D.E.
    Lutetium-177 Prostate-Specific Membrane Antigen Therapy: A Practical Review
    Pract Radiat Oncol (2022) 12, 294-299. PubMed  Europe PubMed DOI  V
  55. Kondo,Y., Kimura,H., Sasaki,I., Watanabe,S., Ohshima,Y., Yagi,Y., Hattori,Y., Koda,M., Kawashima,H., Yasui,H. and Ishioka,N.S.
    Copper-mediated radioiodination and radiobromination via aryl boronic precursor and its application to (125)I/(77)Br-labeled prostate-specific membrane antigen imaging probes
    Bioorg Med Chem (2022) 69, 116915-116915. PubMed  Europe PubMed DOI
  56. Li,Y., Duan,X., Xu,H., Zhang,J., Zhou,H., Zhang,X., Zhang,J., Yang,Z., Hu,Z., Zhang,N., Tian,J. and Yang,X.
    Optimization of ODAP-Urea-based dual-modality PSMA targeting probes for sequential PET-CT and optical imaging
    Bioorg Med Chem (2022) 66, 116810-116810. PubMed  Europe PubMed DOI
  57. Madan,R.A., Mena,E., Lindenberg,L. and Choyke,P.L.
    With New Technology Comes Great Responsibility: Prostate-Specific Membrane Antigen Imaging in Recurrent Prostate Cancer
    J Clin Oncol (2022) 40, 3015-3019. PubMed  Europe PubMed DOI
  58. Olatunji,F.P., Pun,M., Herman,J.W., Romero,O., Maniatopoulos,M., Latoche,J.D., Parise,R.A., Guo,J., Beumer,J.H., Anderson,C.J. and Berkman,C.E.
    Modular Smart Molecules for PSMA-Targeted Chemotherapy
    Mol Cancer Ther (2022) 21, 1701-1709. PubMed  Europe PubMed DOI
  59. Yang,J.U., Kim,S., Ahn,J.H., Kim,M.H., Kil,H.S., Chi,D.Y., Lee,K.C., Lee,Y.J. and Park,J.A.
    Feasibility of Gd-Based prostate cancer targeted magnetic resonance agents using prostate specific membrane antigen
    Biochem Biophys Res Commun (2022) 607, 152-157. PubMed  Europe PubMed DOI
  60. Yuan,W., Liu,B., Sanda,M., Wei,R., Benicky,J., Novakova,Z., Barinka,C. and Goldman,R.
    Glycoforms of human prostate-specific membrane antigen (PSMA) in human cells and prostate tissue
    Prostate (2022) 82, 132-144. PubMed  Europe PubMed DOI
  61. Zha,Z., Choi,S.R., Li,L., Zhao,R., Ploessl,K., Yao,X., Alexoff,D., Zhu,L. and Kung,H.F.
    New PSMA-Targeting Ligands: Transformation from Diagnosis (Ga-68) to Radionuclide Therapy (Lu-177)
    J Med Chem (2022) 65, 13001-13012. PubMed  Europe PubMed DOI
  62. Zhang,X., Chen,K., Jiang,K., He,J., An,Y., He,Z. and Sun,F.
    [Prokaryotic expression of prostate-specific membrane antigen (PSMA) nanoantibody gene and screening of natural phage nanoantibody library]
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2022) 38, 1030-1035. PubMed  Europe PubMed
  63. Zyk,N.Y., Ber,A.P., Nimenko,E.A., Shafikov,R.R., Evteev,S.A., Petrov,S.A., Uspenskaya,A.A., Dashkova,N.S., Ivanenkov,Y.A., Skvortsov,D.A., Beloglazkina,E.K., Majouga,A.G. and Machulkin,A.E.
    Synthesis and initial in vitro evaluation of PSMA-targeting ligands with a modified aromatic moiety at the lysine epsilon-nitrogen atom
    Bioorg Med Chem Lett (2022) 71, 128840-128840. PubMed  Europe PubMed DOI
    64. 2021
  64. Frontera,A. and Bauza,A.
    Glutamate carboxypeptidase II as a model system for designing host-guest units: a theoretical approach
    Org Biomol Chem (2021) 19, 7816-7821. PubMed  Europe PubMed DOI
  65. Plichta,K.A., Graves,S.A. and Buatti,J.M.
    Prostate-Specific Membrane Antigen (PSMA) Theranostics for Treatment of Oligometastatic Prostate Cancer
    Int J Mol Sci (2021) 22 PubMed  Europe PubMed DOI  PMC  EPMC
  66. Zhang,L., Shi,X., Li,Y., Duan,X., Zhang,Z., Fu,H., Yang,X., Tian,J., Hu,Z. and Cui,M.
    Visualizing Tumors in Real Time: A Highly Sensitive PSMA Probe for NIR-II Imaging and Intraoperative Tumor Resection
    J Med Chem (2021) 64, 7735-7745. PubMed  Europe PubMed DOI
    67. 2020
  67. Abecassis,J.P., Ghazzar,N., Peyromaure,M. and Giraud,P.
    Prostate imaging: Contribution of PET PSMA and MRI
    Cancer Radiother (2020) 24, 423-428. PubMed  Europe PubMed DOI
  68. Vornov,J.J., Peters,D., Nedelcovych,M., Hollinger,K., Rais,R. and Slusher,B.S.
    Looking for drugs in all the wrong places: use of GCPII inhibitors outside the brain
    Neurochem Res (2020) 45, 1256-1267. PubMed  Europe PubMed DOI
    69. 2019
  69. Barinka,C., Novakova,Z., Hin,N., Bim,D., Ferraris,D.V., Duvall,B., Kabarriti,G., Tsukamoto,R., Budesinsky,M., Motlova,L., Rojas,C., Slusher,B.S., Rokob,T.A., Rulisek,L. and Tsukamoto,T.
    Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors
    Bioorg Med Chem (2019) 27, 255-264. PubMed  Europe PubMed DOI  I
  70. Neale,J.H. and Yamamoto,T.
    N-acetylaspartylglutamate (NAAG) and glutamate carboxypeptidase II: an abundant peptide neurotransmitter-enzyme system with multiple clinical applications
    Prog Neurobiol (2019) , 101722-101722. PubMed  Europe PubMed DOI
    71. 2018
  71. Choi,J.Y., Ko,J.H. and Jo,S.A.
    HDAC1 regulates the stability of glutamate carboxypeptidase II protein by modulating acetylation status of lysine 479 residue
    Biochem Biophys Res Commun (2018) 497, 416-423. PubMed  Europe PubMed DOI
  72. Endepols,H., Mottaghy,F.M., Simsekyilmaz,S., Bucerius,J., Vogt,F., Winz,O., Richarz,R., Krapf,P., Neumaier,B., Zlatopolskiy,B.D. and Morgenroth,A.
    In vivo molecular imaging of glutamate carboxypeptidase II expression in re-endothelialisation after percutaneous balloon denudation in a rat model
    Sci Rep (2018) 8, 7411-7411. PubMed  Europe PubMed DOI  PMC  EPMC  L
  73. Ptacek,J., Nedvedova,J., Navratil,M., Havlinova,B., Konvalinka,J. and Barinka,C.
    The calcium-binding site of human glutamate carboxypeptidase II is critical for dimerization, thermal stability, and enzymatic activity
    Protein Sci (2018) 27, 1575-1584. PubMed  Europe PubMed DOI
  74. Wu,W., Xu,S., Wang,J., Zhang,K., Zhang,M., Cao,Y., Ren,H., Zheng,D. and Zhong,C.
    Metabolite differences between glutamate carboxypeptidase II gene knockout mice and their wild-type littermates after traumatic brain injury: a 7-tesla (1)H-MRS study
    BMC Neurosci (2018) 19, 75-75. PubMed  Europe PubMed DOI  PMC  EPMC  K  U
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