Literature for peptidase M28.002: aminopeptidase Ap1

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2019
  1. Huang,J.M., Chang,Y.T. and Lin,W.C.
    The biochemical and functional characterization of M28 aminopeptidase protein secreted by Acanthamoeba spp. on host cell interaction
    Molecules24, PubMed  Europe PubMed DOI
  2. Huang,J.M., Chang,Y.T., Shih,M.H., Lin,W.C. and Huang,F.C.
    Identification and characterization of a secreted M28 aminopeptidase protein in Acanthamoeba
    Parasitol Res118, 1865-1874. PubMed  Europe PubMed DOI
  3. 2018
  4. Saraiva,R.G., Fang,J., Kang,S., Anglero-Rodriguez,Y.I., Dong,Y. and Dimopoulos,G.
    Aminopeptidase secreted by Chromobacterium sp. Panama inhibits dengue virus infection by degrading the E protein
    PLoS Negl Trop Dis12, e0006443-e0006443. PubMed  Europe PubMed DOI
  5. White,R.C., Gunderson,F.F., Tyson,J.Y., Richardson,K.H., Portlock,T.J., Garnett,J.A. and Cianciotto,N.P.
    Type II secretion-dependent aminopeptidase LapA and acyltransferase PlaC are redundant for nutrient acquisition during Legionella pneumophila intracellular infection of amoebas
    MBio9, PubMed  Europe PubMed DOI  S
  6. 2016
  7. Hanaya,K., Yoshioka,S., Ariyasu,S., Aoki,S., Shoji,M. and Sugai,T.
    Development of a novel sulfonate ester-based prodrug strategy
    Bioorg Med Chem Lett26, 545-550. PubMed  Europe PubMed DOI  I
  8. 2014
  9. Ariyasu,S., Mizuseda,Y., Hanaya,K. and Aoki,S.
    Design, synthesis and photochemical reactivation of caged prodrugs of 8-hydroxyquinoline-based enzyme inhibitors
    Chem Pharm Bull (Tokyo)62, 642-648. PubMed  Europe PubMed DOI  I
  10. Hernandez-Moreno,A.V., Villasenor,F., Medina-Rivero,E., Perez,N.O., Flores-Ortiz,L.F., Saab-Rincon,G. and Luna-Barcenas,G.
    Kinetics and conformational stability studies of recombinant leucine aminopeptidase
    Int J Biol Macromol64, 306-312. PubMed  Europe PubMed DOI  E
  11. 2012
  12. Chevrier,B. and D'Orchymont,H.
    Vibrio aminopeptidase
    [ISSN:978-0-12-407743-0]3, 1627-1630. DOI
  13. Hanaya,K., Suetsugu,M., Saijo,S., Yamato,I. and Aoki,S.
    Potent inhibition of dinuclear zinc(II) peptidase, an aminopeptidase from Aeromonas proteolytica, by 8-quinolinol derivatives: inhibitor design based on Zn2+ fluorophores, kinetic, and X-ray crystallographic study
    J Biol Inorg Chem17, 517-529. PubMed  Europe PubMed DOI  S  I
  14. 2011
  15. Perez-Sanchez,G., Leal-Guadarrama,L.I., Trelles,I., Perez,N.O. and Medina-Rivero,E.
    High-level production of a recombinant Vibrio proteolyticus leucine aminopeptidase and its use for N-terminal methionine excision from interferon alpha-2b
    Process Biochem46, 1825-1830. DOI
  16. 2010
  17. Frey,S.T., Guilmet,S.L., Egan Iii,R.G., Bennett,A., Soltau,S.R. and Holz,R.C.
    Immobilization of the aminopeptidase from Aeromonas proteolytica on Mg2+/Al3+ layered double hydroxide particles
    ACS Appl Mater Interfaces2, 2828-2832. PubMed  Europe PubMed DOI
  18. Kahn,J., Dutnall,R.N., Matulef,K. and Plesniak,L.A.
    Measurement of k(on) without a rapid-mixing device
    Biochem Mol Biol Educ38, 238-241. PubMed  Europe PubMed DOI  I
  19. 2009
  20. Hartley,M., Yong,W. and Bennett,B.
    Heterologous expression and purification of Vibrio proteolyticus (Aeromonas proteolytica) aminopeptidase: a rapid protocol
    Protein Expr Purif66, 91-101. PubMed  Europe PubMed DOI  E
  21. Sonoda,H., Daimon,K., Yamaji,H. and Sugimura,A.
    Efficient production of active Vibrio proteolyticus aminopeptidase in Escherichia coli by co-expression with engineered vibriolysin
    Appl Microbiol Biotechnol84, 191-198. PubMed  Europe PubMed DOI
  22. 2008
  23. Ataie,N.J., Hoang,Q.Q., Zahniser,M.P., Tu,Y., Milne,A., Petsko,G.A. and Ringe,D.
    Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus
    Biochemistry47, 7673-7683. PubMed  Europe PubMed DOI  S
  24. Chen,S.L., Marino,T., Fang,W.H., Russo,N. and Himo,F.
    Peptide hydrolysis by the binuclear zinc enzyme aminopeptidase from Aeromonas proteolytica: a density functional theory study
    J Phys Chem B112, 2494-2500. PubMed  Europe PubMed DOI
  25. Nirasawa,S. and Hayashi,K.
    Construction of a chimeric aminopeptidase by a combination of gene shuffling and mutagenesis
    Biotechnol Lett30, 363-368. PubMed  Europe PubMed DOI
  26. 2007
  27. Kumar,A., Periyannan,G.R., Narayanan,B., Kittell,A.W., Kim,J.J. and Bennett,B.
    Experimental evidence for a metallohydrolase mechanism in which the nucleophile is not delivered by a metal ion: EPR spectrokinetic and structural studies of aminopeptidase from Vibrio proteolyticus
    Biochem J403, 527-536. PubMed  Europe PubMed DOI
  28. Munih,P., Moulin,A., Stamper,C.C., Bennett,B., Ringe,D., Petsko,G.A. and Holz,R.C.
    X-ray crystallographic characterization of the Co(II)-substituted Tris-bound form of the aminopeptidase from Aeromonas proteolytica
    J Inorg Biochem101, 1099-1107. PubMed  Europe PubMed DOI  S
  29. 2006
  30. [YEAR:4-8-2006]Arima,J., Uesugi,Y., Iwabuchi,M. and Hatanaka,T.
    Study on peptide hydrolysis by aminopeptidases from Streptomyces griseus, Streptomyces septatus and Aeromonas proteolytica
    Appl Microbiol Biotechnol70, 541-547. PubMed  Europe PubMed DOI  P
  31. [YEAR:5-4-2006]Desmarais,W., Bienvenue,D.L., Bzymek,K.P., Petsko,G.A., Ringe,D. and Holz,R.C.
    The high-resolution structures of the neutral and the low pH crystals of aminopeptidase from Aeromonas proteolytica
    J Biol Inorg Chem11, 398-408. PubMed  Europe PubMed DOI  S
  32. 2005
  33. [YEAR:14-11-2005]Bzymek,K.P., Swierczek,S.I., Bennett,B. and Holz,R.C.
    Spectroscopic and thermodynamic characterization of the E151D and E151A altered leucine aminopeptidases from Aeromonas proteolytica
    Inorg Chem44, 8574-8580. PubMed  Europe PubMed DOI
  34. [YEAR:13-9-2005]Bzymek,K.P., Moulin,A., Swierczek,S.I., Ringe,D., Petsko,G.A., Bennett,B. and Holz,R.C.
    Kinetic, spectroscopic, and X-ray crystallographic characterization of the functional E151H aminopeptidase from Aeromonas proteolytica
    Biochemistry44, 12030-12040. PubMed  Europe PubMed DOI  S
  35. 2004
  36. Bzymek,K.P., D'souza,V.M., Chen,G., Campbell,H., Mitchell,A. and Holz,R.C.
    Function of the signal peptide and N- and C-terminal propeptides in the leucine aminopeptidase from Aeromonas proteolytica
    Protein Expr Purif37, 294-305. PubMed  Europe PubMed DOI
  37. [YEAR:11-5-2004]Bzymek,K.P. and Holz,R.C.
    The catalytic role of glutamate 151 in the leucine aminopeptidase from Aeromonas proteolytica
    J Biol Chem279, 31018-31025. PubMed  Europe PubMed DOI
  38. Chevrier,B. and D'Orchymont,H.
    Vibrio aminopeptidase
    [ISSN:0-12-079610-4]2, 963-965.  V
  39. [YEAR:11-5-2004]Schurer,G., Lanig,H. and Clark,T.
    Aeromonas proteolytica aminopeptidase: an investigation of the mode of action using a quantum mechanical/molecular mechanical approach
    Biochemistry43, 5414-5427. PubMed  Europe PubMed DOI
  40. [YEAR:3-8-2004]Stamper,C.C., Bienvenue,D.L., Bennett,B., Ringe,D., Petsko,G.A. and Holz,R.C.
    Spectroscopic and X-ray crystallographic characterization of bestatin bound to the aminopeptidase from Aeromonas (Vibrio) proteolytica
    Biochemistry43, 9620-9628. PubMed  Europe PubMed DOI  S  I
  41. 2003
  42. Holz,R.C., Bzymek,K.P. and Swierczek,S.I.
    Co-catalytic metallopeptidases as pharmaceutical targets
    Curr Opin Chem Biol7, 197-206. PubMed  Europe PubMed DOI
  43. 2002
  44. [YEAR:6-11-2002]Bennett,B., Antholine,W.E., D'souza,V.M., Chen,G., Ustinyuk,L. and Holz,R.C.
    Structurally distinct active sites in the copper(II)-substituted aminopeptidases from Aeromonas proteolytica and Escherichia coli
    J Am Chem Soc124, 13025-13034. PubMed  Europe PubMed DOI
  45. [YEAR:19-3-2002]Bienvenue,D.L., Gilner,D. and Holz,R.C.
    Hydrolysis of thionopeptides by the aminopeptidase from Aeromonas proteolytica: Insight into substrate binding
    Biochemistry41, 3712-3719. PubMed  Europe PubMed DOI
  46. Bienvenue,D.L., Mathew,R.S., Ringe,D. and Holz,R.C.
    The aminopeptidase from Aeromonas proteolytica can function as an esterase
    J Biol Inorg Chem7, 129-135. PubMed  Europe PubMed DOI
  47. Desmarais,W.T., Bienvenue,D.L., Bzymek,K.P., Holz,R.C., Petsko,G.A. and Ringe,D.
    The 1.20 A resolution crystal structure of the aminopeptidase from Aeromonas proteolytica complexed with Tris: a tale of buffer inhibition
    Structure10, 1063-1072. PubMed  Europe PubMed DOI  S
  48. 2001
  49. [YEAR:19-6-2001]Stamper,C., Bennett,B., Edwards,T., Holz,R.C., Ringe,D. and Petsko,G.
    Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinephosphonic acid. Spectroscopic and crystallographic characterization of the transition state of peptide hydrolysis
    Biochemistry40, 7035-7046. PubMed  Europe PubMed
  50. 2000
  51. [YEAR:15-1-2000]Bienvenue,D.L., Bennett,B. and Holz,R.C.
    Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinethiol: kinetic and spectroscopic characterization of a slow, tight-binding inhibitor-enzyme complex
    J Inorg Biochem78, 43-54. PubMed  Europe PubMed DOI  I
  52. 1999
  53. [YEAR:13-7-1999]De Paola,C.C., Bennett,B., Holz,R.C., Ringe,D. and Petsko,G.A.
    1-Butaneboronic acid binding to Aeromonas proteolytica aminopeptidase: a case of arrested development
    Biochemistry38, 9048-9053. PubMed  Europe PubMed DOI  S  I
  54. [YEAR:23-11-1999]Huntington,K.M., Bienvenue,D.L., Wei,Y., Bennett,B., Holz,R.C. and Pei,D.
    Slow-binding inhibition of the aminopeptidase from Aeromonas proteolytica by peptide thiols: synthesis and spectroscopic characterization
    Biochemistry38, 15587-15596. PubMed  Europe PubMed DOI  I
  55. [YEAR:31-8-1999]Ustynyuk,L., Bennett,B., Edwards,T. and Holz,R.C.
    Inhibition of the aminopeptidase from Aeromonas proteolytica by aliphatic alcohols. Characterization of the hydrophobic substrate recognition site
    Biochemistry38, 11433-11439. PubMed  Europe PubMed DOI
  56. 1998
  57. [YEAR:25-11-1998]Bennett,B. and Holz,R.C.
    Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinephosphonic acid, a transition state analogue of peptide hydrolysis
    J Am Chem Soc120, 12139-12140.  I
  58. [YEAR:1-7-1998]Holz,R.C., Bennett,B., Chen,G.J. and Ming,L.J.
    Proton NMR spectroscopy as a probe of dinuclear copper(II) active sites in metalloproteins. Characterization of the hyperactive copper(II)-substituted aminopeptidase from Aeromonas proteolytica
    J Am Chem Soc120, 6329-6335. DOI
  59. [YEAR:1-12-1998]Papir,G., Spungin-Bialik,A., Ben-Meir,D., Fudim,E., Gilboa,R., Greenblatt,H.M., Shoham,G., Lessel,U., Schomburg,D., Ashkenazi,R. and Blumberg,S.
    Inhibition of Streptomyces griseus aminopeptidase and effects of calcium ions on catalysis and binding - Comparisons with the homologous enzyme Aeromonas proteolytica aminopeptidase
    Eur J Biochem258, 313-319. PubMed  Europe PubMed
  60. 1997
  61. Bennett,B. and Holz,R.C.
    Spectroscopically distinct cobalt(II) sites in heterodimetallic forms of the aminopeptidase from Aeromonas proteolytica: Characterization of substrate binding
    Biochemistry36, 9837-9846. PubMed  Europe PubMed DOI  I
  62. Bennett,B. and Holz,R.C.
    EPR studies on the mono- and dicobalt(II)-substituted forms of the aminopeptidase from Aeromonas proteolytica. Insight into the catalytic mechanism of dinuclear hydrolases
    J Am Chem Soc119, 1923-1933. DOI  I
  63. Chen,G., Edwards,T., D'souza,V.M. and Holz,R.C.
    Mechanistic studies on the aminopeptidase from Aeromonas proteolytica: A two-metal ion mechanism for peptide hydrolysis
    Biochemistry36, 4278-4286. PubMed  Europe PubMed DOI
  64. 1996
  65. Chevrier,B., D'Orchymont,H., Schalk,C., Tarnus,C. and Moras,D.
    The structure of the Aeromonas proteolytica aminopeptidase complexed with a hydroxamate inhibitor. Involvement in catalysis of Glu151 and two zinc ions of the co-catalytic unit
    Eur J Biochem237, 393-398. PubMed  Europe PubMed  S  I
  66. Toma,C. and Honma,Y.
    Cloning and genetic analysis of the Vibrio cholerae aminopeptidase gene
    Infect Immun64, 4495-4500. PubMed  Europe PubMed
  67. 1994
  68. Chevrier,B., Schalk,C., D'Orchymont,H., Rondeau,J.M., Moras,D. and Tarnus,C.
    Crystal structure of Aeromonas proteolytica aminopeptidase: a prototypical member of the co-catalytic zinc enzyme family
    Structure2, 283-291. PubMed  Europe PubMed  S
  69. 1992
  70. Guenet,C., Lepage,P. and Harris,B.A.
    Isolation of the leucine aminopeptidase gene from Aeromonas proteolytica. Evidence for an enzyme precursor
    J Biol Chem267, 8390-8395. PubMed  Europe PubMed
  71. Schalk,C., Remy,J.M., Chevrier,B., Moras,D. and Tarnus,C.
    Rapid purification of the Aeromonas proteolytica aminopeptidase: crystallization and preliminary X-ray data
    Arch Biochem Biophys294, 91-97. PubMed  Europe PubMed DOI
  72. Van Heeke,G., Denslow,S., Watkins,J.R., Wilson,K.J. and Wagner,F.W.
    Cloning and nucleotide sequence of the Vibrio proteolyticus aminopeptidase gene
    Biochim Biophys Acta1131, 337-340. PubMed  Europe PubMed DOI
  73. 1985
  74. [YEAR:25-10-1985]Wilkes,S.H. and Prescott,J.M.
    The slow, tight binding of bestatin and amastatin to aminopeptidases
    J Biol Chem260, 13154-13162. PubMed  Europe PubMed  I
  75. 1983
  76. [YEAR:26-4-1983]Baker,J.O., Wilkes,S.H., Bayliss,M.E. and Prescott,J.M.
    Hydroxamates and aliphatic boronic acids: marker inhibitors for aminopeptidase
    Biochemistry22, 2098-2103. PubMed  Europe PubMed  I
  77. [YEAR:25-11-1983]Wilkes,S.H. and Prescott,J.M.
    Stereospecificity of amino acid hydroxamate inhibition of aminopeptidases
    J Biol Chem258, 13517-13521. PubMed  Europe PubMed  I
  78. 1976
  79. Prescott,J.M. and Wilkes,S.H.
    Aeromonas aminopeptidase
    Methods Enzymol45, 530-543. PubMed  Europe PubMed DOI  V
  80. 1973
  81. [YEAR:2-5-1973]Wilkes,S.H., Bayliss,M.E. and Prescott,J.M.
    Specificity of aeromonas aminopeptidase toward oligopeptides and polypeptides
    Eur J Biochem34, 459-466. PubMed  Europe PubMed
  82. 1972
  83. [YEAR:25-2-1972]Wagner,F.W., Wilkes,S.H. and Prescott,J.M.
    Specificity of Aeromonas aminopeptidase toward amino acid amides and dipeptides
    J Biol Chem247, 1208-1210. PubMed  Europe PubMed
  84. 1971
  85. [YEAR:25-3-1971]Prescott,J.M., Wilkes,S.H., Wagner,F.W. and Wilson,K.J.
    Aeromonas aminopeptidase. Improved isolation and some physical properties
    J Biol Chem246, 1756-1764. PubMed  Europe PubMed
  86. 1966
  87. Prescott,J.M. and Wilkes,S.H.
    Aeromonas aminopeptidase: purification and some general properties
    Arch Biochem Biophys117, 328-336. PubMed  Europe PubMed