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Literature for peptidase M28.002: aminopeptidase Ap1

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2019
  1. Huang,J.M., Chang,Y.T., Shih,M.H., Lin,W.C. and Huang,F.C.<br>Identification and characterization of a secreted M28 aminopeptidase protein in Acanthamoeba<br>Parasitol Res (2019) 118, 1865-1874. PubMed  Europe PubMed DOI
  2. Huang,J.M., Chang,Y.T. and Lin,W.C.<br>The biochemical and functional characterization of M28 aminopeptidase protein secreted by Acanthamoeba spp. on host cell interaction<br>Molecules (2019) 24 PubMed  Europe PubMed DOI
    3. 2018
  3. Saraiva,R.G., Fang,J., Kang,S., Anglero-Rodriguez,Y.I., Dong,Y. and Dimopoulos,G.<br>Aminopeptidase secreted by Chromobacterium sp. Panama inhibits dengue virus infection by degrading the E protein<br>PLoS Negl Trop Dis (2018) 12, e0006443-e0006443. PubMed  Europe PubMed DOI
  4. White,R.C., Gunderson,F.F., Tyson,J.Y., Richardson,K.H., Portlock,T.J., Garnett,J.A. and Cianciotto,N.P.<br>Type II secretion-dependent aminopeptidase LapA and acyltransferase PlaC are redundant for nutrient acquisition during Legionella pneumophila intracellular infection of amoebas<br>MBio (2018) 9 PubMed  Europe PubMed DOI  PMC  EPMC  S
    5. 2016
  5. Hanaya,K., Yoshioka,S., Ariyasu,S., Aoki,S., Shoji,M. and Sugai,T.<br>Development of a novel sulfonate ester-based prodrug strategy<br>Bioorg Med Chem Lett (2016) 26, 545-550. PubMed  Europe PubMed DOI  I
    6. 2014
  6. Ariyasu,S., Mizuseda,Y., Hanaya,K. and Aoki,S.<br>Design, synthesis and photochemical reactivation of caged prodrugs of 8-hydroxyquinoline-based enzyme inhibitors<br>Chem Pharm Bull (Tokyo) (2014) 62, 642-648. PubMed  Europe PubMed DOI  I
  7. Hernandez-Moreno,A.V., Villasenor,F., Medina-Rivero,E., Perez,N.O., Flores-Ortiz,L.F., Saab-Rincon,G. and Luna-Barcenas,G.<br>Kinetics and conformational stability studies of recombinant leucine aminopeptidase<br>Int J Biol Macromol (2014) 64, 306-312. PubMed  Europe PubMed DOI  E
    8. 2012
  8. Chevrier,B. and D'Orchymont,H.<br>Vibrio aminopeptidase<br>[ISSN:978-0-12-407743-0] (2012) 3, 1627-1630. DOI
  9. Hanaya,K., Suetsugu,M., Saijo,S., Yamato,I. and Aoki,S.<br>Potent inhibition of dinuclear zinc(II) peptidase, an aminopeptidase from Aeromonas proteolytica, by 8-quinolinol derivatives: inhibitor design based on Zn2+ fluorophores, kinetic, and X-ray crystallographic study<br>J Biol Inorg Chem (2012) 17, 517-529. PubMed  Europe PubMed DOI  S  I
    10. 2011
  10. Perez-Sanchez,G., Leal-Guadarrama,L.I., Trelles,I., Perez,N.O. and Medina-Rivero,E.<br>High-level production of a recombinant Vibrio proteolyticus leucine aminopeptidase and its use for N-terminal methionine excision from interferon alpha-2b<br>Process Biochem (2011) 46, 1825-1830. DOI
    11. 2010
  11. Frey,S.T., Guilmet,S.L., Egan Iii,R.G., Bennett,A., Soltau,S.R. and Holz,R.C.<br>Immobilization of the aminopeptidase from Aeromonas proteolytica on Mg2+/Al3+ layered double hydroxide particles<br>ACS Appl Mater Interfaces (2010) 2, 2828-2832. PubMed  Europe PubMed DOI
  12. Kahn,J., Dutnall,R.N., Matulef,K. and Plesniak,L.A.<br>Measurement of k(on) without a rapid-mixing device<br>Biochem Mol Biol Educ (2010) 38, 238-241. PubMed  Europe PubMed DOI  I
    13. 2009
  13. Hartley,M., Yong,W. and Bennett,B.<br>Heterologous expression and purification of Vibrio proteolyticus (Aeromonas proteolytica) aminopeptidase: a rapid protocol<br>Protein Expr Purif (2009) 66, 91-101. PubMed  Europe PubMed DOI  PMC  EPMC  E
  14. Sonoda,H., Daimon,K., Yamaji,H. and Sugimura,A.<br>Efficient production of active Vibrio proteolyticus aminopeptidase in Escherichia coli by co-expression with engineered vibriolysin<br>Appl Microbiol Biotechnol (2009) 84, 191-198. PubMed  Europe PubMed DOI
    15. 2008
  15. Ataie,N.J., Hoang,Q.Q., Zahniser,M.P., Tu,Y., Milne,A., Petsko,G.A. and Ringe,D.<br>Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus<br>Biochemistry (2008) 47, 7673-7683. PubMed  Europe PubMed DOI  S
  16. Chen,S.L., Marino,T., Fang,W.H., Russo,N. and Himo,F.<br>Peptide hydrolysis by the binuclear zinc enzyme aminopeptidase from Aeromonas proteolytica: a density functional theory study<br>J Phys Chem B (2008) 112, 2494-2500. PubMed  Europe PubMed DOI
  17. Nirasawa,S. and Hayashi,K.<br>Construction of a chimeric aminopeptidase by a combination of gene shuffling and mutagenesis<br>Biotechnol Lett (2008) 30, 363-368. PubMed  Europe PubMed DOI
    18. 2007
  18. Kumar,A., Periyannan,G.R., Narayanan,B., Kittell,A.W., Kim,J.J. and Bennett,B.<br>Experimental evidence for a metallohydrolase mechanism in which the nucleophile is not delivered by a metal ion: EPR spectrokinetic and structural studies of aminopeptidase from Vibrio proteolyticus<br>Biochem J (2007) 403, 527-536. PubMed  Europe PubMed DOI  PMC  EPMC
  19. Munih,P., Moulin,A., Stamper,C.C., Bennett,B., Ringe,D., Petsko,G.A. and Holz,R.C.<br>X-ray crystallographic characterization of the Co(II)-substituted Tris-bound form of the aminopeptidase from Aeromonas proteolytica<br>J Inorg Biochem (2007) 101, 1099-1107. PubMed  Europe PubMed DOI  S
    20. 2006
  20. [YEAR:4-8-2006]Arima,J., Uesugi,Y., Iwabuchi,M. and Hatanaka,T.<br>Study on peptide hydrolysis by aminopeptidases from Streptomyces griseus, Streptomyces septatus and Aeromonas proteolytica<br>Appl Microbiol Biotechnol (4-8-2006) 70, 541-547. PubMed  Europe PubMed DOI  P
  21. [YEAR:5-4-2006]Desmarais,W., Bienvenue,D.L., Bzymek,K.P., Petsko,G.A., Ringe,D. and Holz,R.C.<br>The high-resolution structures of the neutral and the low pH crystals of aminopeptidase from Aeromonas proteolytica<br>J Biol Inorg Chem (5-4-2006) 11, 398-408. PubMed  Europe PubMed DOI  S
    22. 2005
  22. [YEAR:13-9-2005]Bzymek,K.P., Moulin,A., Swierczek,S.I., Ringe,D., Petsko,G.A., Bennett,B. and Holz,R.C.<br>Kinetic, spectroscopic, and X-ray crystallographic characterization of the functional E151H aminopeptidase from Aeromonas proteolytica<br>Biochemistry (13-9-2005) 44, 12030-12040. PubMed  Europe PubMed DOI  S
  23. [YEAR:14-11-2005]Bzymek,K.P., Swierczek,S.I., Bennett,B. and Holz,R.C.<br>Spectroscopic and thermodynamic characterization of the E151D and E151A altered leucine aminopeptidases from Aeromonas proteolytica<br>Inorg Chem (14-11-2005) 44, 8574-8580. PubMed  Europe PubMed DOI
    24. 2004
  24. Bzymek,K.P., D'souza,V.M., Chen,G., Campbell,H., Mitchell,A. and Holz,R.C.<br>Function of the signal peptide and N- and C-terminal propeptides in the leucine aminopeptidase from Aeromonas proteolytica<br>Protein Expr Purif (2004) 37, 294-305. PubMed  Europe PubMed DOI
  25. [YEAR:11-5-2004]Bzymek,K.P. and Holz,R.C.<br>The catalytic role of glutamate 151 in the leucine aminopeptidase from Aeromonas proteolytica<br>J Biol Chem (11-5-2004) 279, 31018-31025. PubMed  Europe PubMed DOI
  26. Chevrier,B. and D'Orchymont,H.<br>Vibrio aminopeptidase<br>[ISSN:0-12-079610-4] (2004) 2, 963-965.  V
  27. [YEAR:11-5-2004]Schurer,G., Lanig,H. and Clark,T.<br>Aeromonas proteolytica aminopeptidase: an investigation of the mode of action using a quantum mechanical/molecular mechanical approach<br>Biochemistry (11-5-2004) 43, 5414-5427. PubMed  Europe PubMed DOI
  28. [YEAR:3-8-2004]Stamper,C.C., Bienvenue,D.L., Bennett,B., Ringe,D., Petsko,G.A. and Holz,R.C.<br>Spectroscopic and X-ray crystallographic characterization of bestatin bound to the aminopeptidase from Aeromonas (Vibrio) proteolytica<br>Biochemistry (3-8-2004) 43, 9620-9628. PubMed  Europe PubMed DOI  S  I
    29. 2003
  29. Holz,R.C., Bzymek,K.P. and Swierczek,S.I.<br>Co-catalytic metallopeptidases as pharmaceutical targets<br>Curr Opin Chem Biol (2003) 7, 197-206. PubMed  Europe PubMed DOI
    30. 2002
  30. [YEAR:6-11-2002]Bennett,B., Antholine,W.E., D'souza,V.M., Chen,G., Ustinyuk,L. and Holz,R.C.<br>Structurally distinct active sites in the copper(II)-substituted aminopeptidases from Aeromonas proteolytica and Escherichia coli<br>J Am Chem Soc (6-11-2002) 124, 13025-13034. PubMed  Europe PubMed DOI  PMC  EPMC
  31. Bienvenue,D.L., Mathew,R.S., Ringe,D. and Holz,R.C.<br>The aminopeptidase from Aeromonas proteolytica can function as an esterase<br>J Biol Inorg Chem (2002) 7, 129-135. PubMed  Europe PubMed DOI
  32. [YEAR:19-3-2002]Bienvenue,D.L., Gilner,D. and Holz,R.C.<br>Hydrolysis of thionopeptides by the aminopeptidase from Aeromonas proteolytica: Insight into substrate binding<br>Biochemistry (19-3-2002) 41, 3712-3719. PubMed  Europe PubMed DOI
  33. Desmarais,W.T., Bienvenue,D.L., Bzymek,K.P., Holz,R.C., Petsko,G.A. and Ringe,D.<br>The 1.20 A resolution crystal structure of the aminopeptidase from Aeromonas proteolytica complexed with Tris: a tale of buffer inhibition<br>Structure (2002) 10, 1063-1072. PubMed  Europe PubMed DOI  S
    34. 2001
  34. [YEAR:19-6-2001]Stamper,C., Bennett,B., Edwards,T., Holz,R.C., Ringe,D. and Petsko,G.<br>Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinephosphonic acid. Spectroscopic and crystallographic characterization of the transition state of peptide hydrolysis<br>Biochemistry (19-6-2001) 40, 7035-7046. PubMed  Europe PubMed
    35. 2000
  35. [YEAR:15-1-2000]Bienvenue,D.L., Bennett,B. and Holz,R.C.<br>Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinethiol: kinetic and spectroscopic characterization of a slow, tight-binding inhibitor-enzyme complex<br>J Inorg Biochem (15-1-2000) 78, 43-54. PubMed  Europe PubMed DOI  I
    36. 1999
  36. [YEAR:13-7-1999]De Paola,C.C., Bennett,B., Holz,R.C., Ringe,D. and Petsko,G.A.<br>1-Butaneboronic acid binding to Aeromonas proteolytica aminopeptidase: a case of arrested development<br>Biochemistry (13-7-1999) 38, 9048-9053. PubMed  Europe PubMed DOI  S  I
  37. [YEAR:23-11-1999]Huntington,K.M., Bienvenue,D.L., Wei,Y., Bennett,B., Holz,R.C. and Pei,D.<br>Slow-binding inhibition of the aminopeptidase from Aeromonas proteolytica by peptide thiols: synthesis and spectroscopic characterization<br>Biochemistry (23-11-1999) 38, 15587-15596. PubMed  Europe PubMed DOI  I
  38. [YEAR:31-8-1999]Ustynyuk,L., Bennett,B., Edwards,T. and Holz,R.C.<br>Inhibition of the aminopeptidase from Aeromonas proteolytica by aliphatic alcohols. Characterization of the hydrophobic substrate recognition site<br>Biochemistry (31-8-1999) 38, 11433-11439. PubMed  Europe PubMed DOI
    39. 1998
  39. [YEAR:25-11-1998]Bennett,B. and Holz,R.C.<br>Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinephosphonic acid, a transition state analogue of peptide hydrolysis<br>J Am Chem Soc (25-11-1998) 120, 12139-12140.  I
  40. [YEAR:1-7-1998]Holz,R.C., Bennett,B., Chen,G.J. and Ming,L.J.<br>Proton NMR spectroscopy as a probe of dinuclear copper(II) active sites in metalloproteins. Characterization of the hyperactive copper(II)-substituted aminopeptidase from Aeromonas proteolytica<br>J Am Chem Soc (1-7-1998) 120, 6329-6335. DOI
  41. [YEAR:1-12-1998]Papir,G., Spungin-Bialik,A., Ben-Meir,D., Fudim,E., Gilboa,R., Greenblatt,H.M., Shoham,G., Lessel,U., Schomburg,D., Ashkenazi,R. and Blumberg,S.<br>Inhibition of Streptomyces griseus aminopeptidase and effects of calcium ions on catalysis and binding - Comparisons with the homologous enzyme Aeromonas proteolytica aminopeptidase<br>Eur J Biochem (1-12-1998) 258, 313-319. PubMed  Europe PubMed
    42. 1997
  42. Bennett,B. and Holz,R.C.<br>EPR studies on the mono- and dicobalt(II)-substituted forms of the aminopeptidase from Aeromonas proteolytica. Insight into the catalytic mechanism of dinuclear hydrolases<br>J Am Chem Soc (1997) 119, 1923-1933. DOI  I
  43. Bennett,B. and Holz,R.C.<br>Spectroscopically distinct cobalt(II) sites in heterodimetallic forms of the aminopeptidase from Aeromonas proteolytica: Characterization of substrate binding<br>Biochemistry (1997) 36, 9837-9846. PubMed  Europe PubMed DOI  I
  44. Chen,G., Edwards,T., D'souza,V.M. and Holz,R.C.<br>Mechanistic studies on the aminopeptidase from Aeromonas proteolytica: A two-metal ion mechanism for peptide hydrolysis<br>Biochemistry (1997) 36, 4278-4286. PubMed  Europe PubMed DOI
    45. 1996
  45. Chevrier,B., D'Orchymont,H., Schalk,C., Tarnus,C. and Moras,D.<br>The structure of the Aeromonas proteolytica aminopeptidase complexed with a hydroxamate inhibitor. Involvement in catalysis of Glu151 and two zinc ions of the co-catalytic unit<br>Eur J Biochem (1996) 237, 393-398. PubMed  Europe PubMed  S  I
  46. Toma,C. and Honma,Y.<br>Cloning and genetic analysis of the Vibrio cholerae aminopeptidase gene<br>Infect Immun (1996) 64, 4495-4500. PubMed  Europe PubMed  PMC  EPMC
    47. 1994
  47. Chevrier,B., Schalk,C., D'Orchymont,H., Rondeau,J.M., Moras,D. and Tarnus,C.<br>Crystal structure of Aeromonas proteolytica aminopeptidase: a prototypical member of the co-catalytic zinc enzyme family<br>Structure (1994) 2, 283-291. PubMed  Europe PubMed  S
    48. 1992
  48. Guenet,C., Lepage,P. and Harris,B.A.<br>Isolation of the leucine aminopeptidase gene from Aeromonas proteolytica. Evidence for an enzyme precursor<br>J Biol Chem (1992) 267, 8390-8395. PubMed  Europe PubMed
  49. Schalk,C., Remy,J.M., Chevrier,B., Moras,D. and Tarnus,C.<br>Rapid purification of the Aeromonas proteolytica aminopeptidase: crystallization and preliminary X-ray data<br>Arch Biochem Biophys (1992) 294, 91-97. PubMed  Europe PubMed DOI
  50. Van Heeke,G., Denslow,S., Watkins,J.R., Wilson,K.J. and Wagner,F.W.<br>Cloning and nucleotide sequence of the Vibrio proteolyticus aminopeptidase gene<br>Biochim Biophys Acta (1992) 1131, 337-340. PubMed  Europe PubMed DOI
    51. 1985
  51. [YEAR:25-10-1985]Wilkes,S.H. and Prescott,J.M.<br>The slow, tight binding of bestatin and amastatin to aminopeptidases<br>J Biol Chem (25-10-1985) 260, 13154-13162. PubMed  Europe PubMed  I
    52. 1983
  52. [YEAR:26-4-1983]Baker,J.O., Wilkes,S.H., Bayliss,M.E. and Prescott,J.M.<br>Hydroxamates and aliphatic boronic acids: marker inhibitors for aminopeptidase<br>Biochemistry (26-4-1983) 22, 2098-2103. PubMed  Europe PubMed  I
  53. [YEAR:25-11-1983]Wilkes,S.H. and Prescott,J.M.<br>Stereospecificity of amino acid hydroxamate inhibition of aminopeptidases<br>J Biol Chem (25-11-1983) 258, 13517-13521. PubMed  Europe PubMed  I
    54. 1976
  54. Prescott,J.M. and Wilkes,S.H.<br>Aeromonas aminopeptidase<br>Methods Enzymol (1976) 45, 530-543. PubMed  Europe PubMed DOI  V
    55. 1973
  55. [YEAR:2-5-1973]Wilkes,S.H., Bayliss,M.E. and Prescott,J.M.<br>Specificity of aeromonas aminopeptidase toward oligopeptides and polypeptides<br>Eur J Biochem (2-5-1973) 34, 459-466. PubMed  Europe PubMed
    56. 1972
  56. [YEAR:25-2-1972]Wagner,F.W., Wilkes,S.H. and Prescott,J.M.<br>Specificity of Aeromonas aminopeptidase toward amino acid amides and dipeptides<br>J Biol Chem (25-2-1972) 247, 1208-1210. PubMed  Europe PubMed
    57. 1971
  57. [YEAR:25-3-1971]Prescott,J.M., Wilkes,S.H., Wagner,F.W. and Wilson,K.J.<br>Aeromonas aminopeptidase. Improved isolation and some physical properties<br>J Biol Chem (25-3-1971) 246, 1756-1764. PubMed  Europe PubMed
    58. 1966
  58. Prescott,J.M. and Wilkes,S.H.<br>Aeromonas aminopeptidase: purification and some general properties<br>Arch Biochem Biophys (1966) 117, 328-336. PubMed  Europe PubMed

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