Literature for peptidase M24.009: aminopeptidase P1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, M Mutation, P Specificity, K Knockout, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2022
  1. Bae,Y.S., Yoon,S.H., Kim,Y.S., Oh,S.P., Song,W.S., Cha,J.H. and Kim,M.H.
    Suppression of exaggerated NMDAR activity by memantine treatment ameliorates neurological and behavioral deficits in aminopeptidase P1-deficient mice
    Exp Mol Med54, 1109-1124. PubMed  Europe PubMed DOI
  2. Silva,N., Castellano-Pozo,M., Matsuzaki,K., Barroso,C., Roman-Trufero,M., Craig,H., Brooks,D.R., Isaac,R.E., Boulton,S.J. and Martinez-Perez,E.
    Proline-specific aminopeptidase P prevents replication-associated genome instability
    PLoS Genet18, e1010025-e1010025. PubMed  Europe PubMed DOI
  3. Zeng,J., Zhang,R., Ning Ma,K., Han,L.L., Yan,S.W., Liu,R.D., Zhang,X., Wang,Z.Q. and Cui,J.
    Characterization of a novel aminopeptidase P from Trichinella spiralis and its participation in the intrusion of intestinal epithelial cells
    Exp Parasitol242, 108376-108376. PubMed  Europe PubMed DOI
  4. 2021
  5. Yoon,S.H., Bae,Y.S., Oh,S.P., Song,W.S., Chang,H. and Kim,M.H.
    Altered hippocampal gene expression, glial cell population, and neuronal excitability in aminopeptidase P1 deficiency
    Sci Rep11, 932-932. PubMed  Europe PubMed DOI
  6. Zeng,J., Zhang,X.Z., Zhang,R., Yan,S.W., Song,Y.Y., Long,S.R., Dan Liu,R., Wang,Z.Q. and Cui,J.
    Vaccination of mice with recombinant novel aminopeptidase P and cathepsin X alone or in combination induces protective immunity against Trichinella spiralis infection
    Acta Trop224, 106125-106125. PubMed  Europe PubMed DOI
  7. 2020
  8. Dunaevsky,Y.E., Tereshchenkova,V.F., Oppert,B., Belozersky,M.A., Filippova,I.Y. and Elpidina,E.N.
    Human proline specific peptidases: a comprehensive analysis
    Biochim Biophys Acta Gen Subj1864, 129636-129636. PubMed  Europe PubMed DOI  V
  9. 2018
  10. Bae,Y.S., Yoon,S.H., Han,J.Y., Woo,J., Cho,Y.S., Kwon,S.K., Bae,Y.C., Kim,D., Kim,E. and Kim,M.H.
    Deficiency of aminopeptidase P1 causes behavioral hyperactivity, cognitive deficits, and hippocampal neurodegeneration
    Genes Brain Behav17, 126-138. PubMed  Europe PubMed DOI  M
  11. Chang,H.C., Kung,C.C., Chang,T.T., Jao,S.C., Hsu,Y.T. and Li,W.S.
    Investigation of the proton relay system operative in human cystosolic aminopeptidase P
    PLoS ONE13, e0190816-e0190816. PubMed  Europe PubMed DOI
  12. 2017
  13. Drendel,V., Heckelmann,B., Chen,C.Y., Weisser,J., Espadas,G., Schell,C., Sabido,E., Werner,M., Jilg,C.A. and Schilling,O.
    Proteome profiling of clear cell renal cell carcinoma in von Hippel-Lindau patients highlights upregulation of Xaa-Pro aminopeptidase-1, an anti-proliferative and anti-migratory exoprotease
    Oncotarget8, 100066-100078. PubMed  Europe PubMed DOI
  14. 2015
  15. Hye Khan,M.A., Sharma,A., Rarick,K.R., Roman,R.J., Harder,D.R. and Imig,J.D.
    Elevated aminopeptidase P attenuates cerebral arterial responses to bradykinin in fawn-hooded hypertensive rats
    PLoS ONE10, e0145335-e0145335. PubMed  Europe PubMed DOI  I
  16. 2012
  17. Cottrell,G.S. and Turner,A.J.
    Aminopeptidase P1
    [ISSN:978-0-12-407743-0]3, 1525-1528. DOI
  18. Wu,S., Liu,S., Sim,S. and Pedersen,L.G.
    Weakly antiferromagentic coupling via superexchange interaction between Mn(II)-Mn(II) atoms: a QM/MM study of the active site of human cytosolic X-propyl aminopeptidase P
    J Phys Chem Lett3, 2293-2297. PubMed  Europe PubMed DOI
  19. Yoon,S.H., Bae,Y.S., Mun,M.S., Park,K.Y., Ye,S.K., Kim,E. and Kim,M.H.
    Developmental retardation, microcephaly, and peptiduria in mice without aminopeptidase P1
    Biochem Biophys Res Commun429, 204-209. PubMed  Europe PubMed DOI  K
  20. 2011
  21. Kaewkiattiyot,S., Honsawek,S., Vejchapipat,P., Chongsrisawat,V. and Poovorawan,Y.
    Association of X-prolyl aminopeptidase 1 rs17095355 polymorphism with biliary atresia in Thai children
    Hepatol Res41, 1249-1252. PubMed  Europe PubMed DOI  M
  22. 2009
  23. Abid,K., Rochat,B., Lassahn,P.G., Stocklin,R., Michalet,S., Brakch,N., Aubert,J.F., Vatansever,B., Tella,P., De Meester,I. and Grouzmann,E.
    Kinetic study of neuropeptide Y (NPY) proteolysis in blood and identification of NPY3-35: a new peptide generated by plasma kallikrein
    J Biol Chem284, 24715-24724. PubMed  Europe PubMed DOI  P
  24. 2008
  25. Hsu,Y.T., Su,C.Y., Du,H.C., Jao,S.C. and Li,W.S.
    Evaluation of organophosphorus chemicals-degrading enzymes: a comparison of Escherichia coli and human cytosolic aminopeptidase P
    Chem Biodivers5, 1401-1411. PubMed  Europe PubMed DOI
  26. Li,X., Lou,Z., Li,X., Zhou,W., Ma,M., Cao,Y., Geng,Y., Bartlam,M., Zhang,X.C. and Rao,Z.
    Structure of human cytosolic X-prolyl aminopeptidase: a double Mn(II)-dependent dimeric enzyme with a novel three-domain subunit
    J Biol Chem283, 22858-22866. PubMed  Europe PubMed DOI  S
  27. 2005
  28. [YEAR:15-3-2005]Ersahin,C., Szpaderska,A.M., Orawski,A.T. and Simmons,W.H.
    Aminopeptidase P isozyme expression in human tissues and peripheral blood mononuclear cell fractions
    Arch Biochem Biophys435, 303-310. PubMed  Europe PubMed DOI
  29. 2004
  30. Turner,A.J. and Cottrell,G.S.
    Aminopeptidase P1
    [ISSN:0-12-079610-4]2, 931-933.  V
  31. 2002
  32. [YEAR:15-6-2002]Adam,A., Cugno,M., Molinaro,G., Perez,M., Lepage,Y. and Agostoni,A.
    Aminopeptidase P in individuals with a history of angio-oedema on ACE inhibitors
    Lancet359, 2088-2089. PubMed  Europe PubMed DOI
  33. Kulkarni,G.V. and Deobagkar,D.D.
    A cytosolic form of aminopeptidase P from Drosophila melanogaster: Molecular cloning and characterization
    J Biochem131, 445-452. PubMed  Europe PubMed
  34. 2001
  35. [YEAR:24-8-2001]Hauser,F., Strassner,J. and Schaller,A.
    Cloning, expression, and characterization of tomato (Lycopersicon esculentum) aminopeptidase P
    J Biol Chem276, 31732-31737. PubMed  Europe PubMed DOI
  36. 2000
  37. [YEAR:12-12-2000]Cottrell,G.S., Hooper,N.M. and Turner,A.J.
    Cloning, expression, and characterization of human cytosolic aminopeptidase P: a single manganese(II)-dependent enzyme
    Biochemistry39, 15121-15128. PubMed  Europe PubMed DOI  E
  38. [YEAR:1-6-2000]Sprinkle,T.J., Caldwell,C. and Ryan,J.W.
    Cloning, chromosomal sublocalization of the human soluble aminopeptidase P gene (XPNPEP1) to 10q25.3 and conservation of the putative proton shuttle and metal ligand binding sites with XPNPEP2
    Arch Biochem Biophys378, 51-56. PubMed  Europe PubMed DOI
  39. 1999
  40. [YEAR:19-3-1999]Czirjak,G., Burkhart,W.A., Moyer,M.B., Antal,J., Shears,S.B. and Enyedi,P.
    Cloning and functional expression of the cytoplasmic form of rat aminopeptidase P
    Biochim Biophys Acta1444, 326-336. PubMed  Europe PubMed DOI
  41. Gilmartin,L. and O'Cuinn,G.
    Dipeptidyl aminopeptidase IV and aminopeptidase P, two proline specific enzymes from the cytoplasm of guinea-pig brain: their role in metabolism of peptides containing consecutive prolines
    Neurosci Res34, 1-11. PubMed  Europe PubMed DOI
  42. 1997
  43. Vanhoof,G., Goossens,F., Juliano,M.A., Juliano,L., Hendriks,D., Schatteman,K., Lin,A.H. and Scharpe,S.
    Isolation and sequence analysis of a human cDNA clone (XPNPEPL) homologous to X-prolyl aminopeptidase (aminopeptidase P)
    Cytogenet Cell Genet78, 275-280. PubMed  Europe PubMed
  44. 1992
  45. [YEAR:15-11-1992]Rusu,I. and Yaron,A.
    Aminopeptidase P from human leukocytes
    Eur J Biochem210, 93-100. PubMed  Europe PubMed DOI
  46. Vanhoof,G., De Block,J., De Meester,I., Scharpe,S. and De Potter,W.P.
    Localization and characterization of aminopeptidase P in bovine adrenal medulla
    Neurochem Int21, 203-208. PubMed  Europe PubMed DOI
  47. 1991
  48. Harbeck,H.T. and Mentlein,R.
    Aminopeptidase P from rat brain. Purification and action on bioactive peptides
    Eur J Biochem198, 451-458. PubMed  Europe PubMed  P
  49. 1987
  50. [YEAR:1-5-1987]Holtzman,E.J., Pillay,G., Rosenthal,T. and Yaron,A.
    Aminopeptidase P activity in rat organs and human serum
    Anal Biochem162, 476-484. PubMed  Europe PubMed