Literature for peptidase M16.009: eupitrilysin

(Topics flags: S Structure, M Mutation, P Specificity, K Knockout, E Expression, V Review, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

2023
1. Di Donfrancesco,A., Berlingieri,C., Giacomello,M., Frascarelli,C., Magalhaes Rebelo,A.P., Bindoff,L.A., Reeval,S., Renbaum,P., Santorelli,F.M., Massaro,G., Viscomi,C., Zeviani,M., Ghezzi,D., Bottani,E. and Brunetti,D.
   PPAR-gamma agonist pioglitazone recovers mitochondrial quality control in fibroblasts from PITRM1-deficient patients
   Front Pharmacol14, 1220620-1220620. PubMed  Europe PubMed DOI
2. Dou,Y. and Tan,Y.
   Presequence protease reverses mitochondria-specific amyloid-beta-induced mitophagy to protect mitochondria
   FASEB J37, e22890-e22890. PubMed  Europe PubMed DOI
2022
3. Liang,W.G., Wijaya,J., Wei,H., Noble,A.J., Mancl,J.M., Mo,S., Lee,D., Lin King,J.V., Pan,M., Liu,C., Koehler,C.M., Zhao,M., Potter,C.S., Carragher,B., Li,S. and Tang,W.J.
   Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition
   Nat Commun13, 1833-1833. PubMed  Europe PubMed DOI
2020
4. Brunetti,D., Bottani,E., Segala,A., Marchet,S., Rossi,F., Orlando,F., Malavolta,M., Carruba,M.O., Lamperti,C., Provinciali,M., Nisoli,E. and Valerio,A.
   Targeting Multiple Mitochondrial Processes by a Metabolic Modulator Prevents Sarcopenia and Cognitive Decline in SAMP8 Mice
   Front Pharmacol11, 1171-1171. PubMed  Europe PubMed DOI
5. Perez,M.J., Ivanyuk,D., Panagiotakopoulou,V., Di Napoli,G., Kalb,S., Brunetti,D., Al-Shaana,R., Kaeser,S.A., Fraschka,S.A., Jucker,M., Zeviani,M., Viscomi,C. and Deleidi,M.
   Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids
   Mol Psychiatry PubMed  Europe PubMed DOI
2019
6. Jiang,K., Yang,Z., Cui,W., Su,K., Ma,J.Z., Payne,T.J. and Li,M.D.
   An exome-wide association study identifies new susceptibility loci for age of smoking initiation in African- and European-American populations
   Nicotine Tob Res21, 707-713. PubMed  Europe PubMed DOI  M
2018
7. Langer,Y., Aran,A., Gulsuner,S., Abu Libdeh,B., Renbaum,P., Brunetti,D., Teixeira,P.F., Walsh,T., Zeligson,S., Ruotolo,R., Beeri,R., Dweikat,I., Shahrour,M., Weinberg-Shukron,A., Zahdeh,F., Baruffini,E., Glaser,E., King,M.C., Levy-Lahad,E., Zeviani,M. and Segel,R.
   Mitochondrial PITRM1 peptidase loss-of-function in childhood cerebellar atrophy
   J Med Genet55, 599-606. PubMed  Europe PubMed DOI  M
8. Smith-Carpenter,J.E. and Alper,B.J.
   Functional requirement for human pitrilysin metallopeptidase 1 arginine 183, mutated in amyloidogenic neuropathy
   Protein Sci27, 861-873. PubMed  Europe PubMed DOI  E  M
2016
9. Brunetti,D., Torsvik,J., Dallabona,C., Teixeira,P., Sztromwasser,P., Fernandez-Vizarra,E., Cerutti,R., Reyes,A., Preziuso,C., D'Amati,G., Baruffini,E., Goffrini,P., Viscomi,C., Ferrero,I., Boman,H., Telstad,W., Johansson,S., Glaser,E., Knappskog,P.M., Zeviani,M. and Bindoff,L.A.
   Defective PITRM1 mitochondrial peptidase is associated with Abeta amyloidotic neurodegeneration
   EMBO Mol Med8, 176-190. PubMed  Europe PubMed DOI  M
2015
10. Fang,D., Wang,Y., Zhang,Z., Du,H., Yan,S., Sun,Q., Zhong,C., Wu,L., Vangavaragu,J.R., Yan,S., Hu,G., Guo,L., Rabinowitz,M., Glaser,E., Arancio,O., Sosunov,A.A., McKhann,G.M., Chen,J.X. and Yan,S.S.
    Increased neuronal PreP activity reduces Abeta accumulation, attenuates neuroinflammation and improves mitochondrial and synaptic function in Alzheimer disease's mouse model
    Hum Mol Genet24, 5198-5210. PubMed  Europe PubMed DOI  U
11. Guan,H., Chow,K.M., Song,E., Verma,N., Despa,F. and Hersh,L.B.
    The mitochondrial peptidase pitrilysin degrades islet amyloid polypeptide in beta-cells
    PLoS ONE10, e0133263-e0133263. PubMed  Europe PubMed DOI
2014
12. Chen,J., Teixeira,P.F., Glaser,E. and Levine,R.L.
    Mechanism of oxidative inactivation of human presequence protease by hydrogen peroxide
    Free Radic Biol Med77, 57-63. PubMed  Europe PubMed DOI
13. King,J.V., Liang,W.G., Scherpelz,K.P., Schilling,A.B., Meredith,S.C. and Tang,W.J.
    Molecular basis of substrate recognition and degradation by human presequence protease
    Structure22, 996-1007. PubMed  Europe PubMed DOI  S
14. Kmiec,B., Teixeira,P.F. and Glaser,E.
    Shredding the signal: targeting peptide degradation in mitochondria and chloroplasts
    Trends Plant Sci19, 771-778. PubMed  Europe PubMed DOI
15. Vangavaragu,J.R., Valasani,K.R., Gan,X. and Yan,S.S.
    Identification of human presequence protease (hPreP) agonists for the treatment of Alzheimer's disease
    Eur J Med Chem76, 506-516. PubMed  Europe PubMed DOI
2013
16. Teixeira,P.F. and Glaser,E.
    Processing peptidases in mitochondria and chloroplasts
    Biochim Biophys Acta1833, 360-370. PubMed  Europe PubMed DOI  V
2012
17. Filipe Teixeira,P., Moreira Pinho,C., Branca,R.M., Lehtio,J., Levine,R.L. and Glaser,E.
    In vitro oxidative inactivation of human presequence protease (hPreP)
    Free Radic Biol Med53, 2188-2195. PubMed  Europe PubMed DOI
18. Kmiec,B. and Glaser,E.
    A novel mitochondrial and chloroplast peptidasome, PreP
    Physiol Plant145, 180-186. PubMed  Europe PubMed DOI  K
19. Mzhavia,N. and Devi,L.A.
    Eupitrilysin
    [ISSN:978-0-12-407744-7]3, 1457-1459. DOI
2011
20. Alikhani,N., Guo,L., Yan,S., Du,H., Pinho,C.M., Chen,J.X., Glaser,E. and Yan,S.S.
    Decreased proteolytic activity of the mitochondrial amyloid-beta degrading enzyme, PreP peptidasome, in Alzheimer's disease brain mitochondria
    J Alzheimers Dis27, 75-87. PubMed  Europe PubMed DOI
21. Alikhani,N., Berglund,A.K., Engmann,T., Spanning,E., Vogtle,F.N., Pavlov,P., Meisinger,C., Langer,T. and Glaser,E.
    Targeting capacity and conservation of PreP homologues localization in mitochondria of different species
    J Mol Biol410, 400-410. PubMed  Europe PubMed DOI
2010
22. Glaser,E. and Alikhani,N.
    The organellar peptidasome, PreP: a journey from Arabidopsis to Alzheimer's disease
    Biochim Biophys Acta1797, 1076-1080. PubMed  Europe PubMed DOI  S
23. Pinho,C.M., Bjork,B.F., Alikhani,N., Backman,H.G., Eneqvist,T., Fratiglioni,L., Glaser,E. and Graff,C.
    Genetic and biochemical studies of SNPs of the mitochondrial A beta-degrading protease, hPreP
    Neurosci Lett469, 204-208. PubMed  Europe PubMed DOI
2009
24. Alikhani,N., Ankarcrona,M. and Glaser,E.
    Mitochondria and Alzheimer's disease: amyloid-beta peptide uptake and degradation by the presequence protease, hPreP
    J Bioenerg Biomembr41, 447-451. PubMed  Europe PubMed DOI
25. Chow,K.M., Gakh,O., Payne,I.C., Juliano,M.A., Juliano,L., Isaya,G. and Hersh,L.B.
    Mammalian pitrilysin: substrate specificity and mitochondrial targeting
    Biochemistry48, 2868-2877. PubMed  Europe PubMed DOI  P
2006
26. [YEAR:18-7-2006]Falkevall,A., Alikhani,N., Bhushan,S., Pavlov,P.F., Busch,K., Johnson,K.A., Eneqvist,T., Tjernberg,L., Ankarcrona,M. and Glaser,E.
    Degradation of the amyloid beta-protein by the novel mitochondrial peptidasome, PreP
    J Biol Chem281, 29096-29104. PubMed  Europe PubMed DOI
2004
27. Mzhavia,N. and Devi,L.A.
    Metalloprotease 1
    [ISSN:0-12-079610-4]2, 890-892.  V
2003
28. [YEAR:1-1-2003]Suemizu,H., Aiba,K., Yoshikawa,T., Sharov,A.A., Shimozawa,N., Tamaoki,N. and Ko,M.S.
    Expression profiling of placentomegaly associated with nuclear transplantation of mouse ES cells
    Dev Biol253, 36-53. PubMed  Europe PubMed DOI
1999
29. Mzhavia,N., Berman,Y.L., Qian,Y., Yan,L. and Devi,L.A.
    Cloning, expression, and characterization of human metalloprotease 1: a novel member of the pitrilysin family of metalloendoproteases
    DNA Cell Biol18, 369-380. PubMed  Europe PubMed DOI