Literature for peptidase M14.017: carboxypeptidase A4

(Topics flags: S Structure, M Mutation, P Specificity, K Knockout. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Adeluola,A.A., Hossain,M.S. and Amin,A.R.M.R.
   Carboxypeptidase A4: A Biomarker for Cancer Aggressiveness and Drug Resistance
   Cancers (Basel) (2025) 17 PubMed  Europe PubMed DOI  PMC  EPMC
2024
2. Choi,Y.S., Jeon,M.J., Doolittle,W.K.L., Song,D.E., Kim,K., Kim,W.B. and Kim,W.G.
   Macrophage-induced carboxypeptidase A4 promotes the progression of anaplastic thyroid cancer
   Thyroid (2024) 34, 1150-1162. PubMed  Europe PubMed DOI  K
2023
3. Liu,X., Liang,H., Fang,H., Xiao,J., Yang,C., Zhou,Z., Feng,J. and Chen,C.
   Angiopoietin-1 promotes triple-negative breast cancer cell proliferation by upregulating carboxypeptidase A4
   Acta Biochim Biophys Sin (Shanghai) (2023) 55, 1487-1495. PubMed  Europe PubMed DOI  K
2021
4. Siddhuraj,P., Clausson,C.M., Sanden,C., Alyamani,M., Kadivar,M., Marsal,J., Wallengren,J., Bjermer,L. and Erjefalt,J.S.
   Lung Mast Cells Have a High Constitutive Expression of Carboxypeptidase A3 mRNA That Is Independent from Granule-Stored CPA3
   Cells (2021) 10 PubMed  Europe PubMed DOI  PMC  EPMC
2020
5. Gao,W., Guo,N., Zhao,S., Chen,Z., Zhang,W., Yan,F., Liao,H. and Chi,K.
   Carboxypeptidase A4 (CPA4) promotes cardiomyocyte hypertrophy through activating PI3K-AKT-mTOR signaling
   Biosci Rep (2020) PubMed  Europe PubMed DOI
6. Moon,Y., Moon,R., Roh,H., Chang,S., Lee,S. and Park,H.
   HIF-1alpha-Dependent Induction of Carboxypeptidase A4 and Carboxypeptidase E in Hypoxic Human Adipose-Derived Stem Cells
   Mol Cells (2020) 43, 945-952. PubMed  Europe PubMed DOI
2019
7. Fu,Y., Su,L., Cai,M., Yao,B., Xiao,S., He,Q., Xu,L., Yang,L., Zhao,C., Wan,T., Shao,L., Wang,L. and Huang,X.
   Downregulation of CPA4 inhibits non small-cell lung cancer growth by suppressing the AKT/c-MYC pathway
   Mol Carcinog (2019) 58, 2026-2039. PubMed  Europe PubMed DOI
8. Pan,H., Pan,J., Ji,L., Song,S., Lv,H., Yang,Z. and Guo,Y.
   Carboxypeptidase A4 promotes cell growth via activating STAT3 and ERK signaling pathways and predicts a poor prognosis in colorectal cancer
   Int J Biol Macromol (2019) 138, 125-134. PubMed  Europe PubMed DOI
9. Zhang,H., Hao,C., Wang,H., Shang,H. and Li,Z.
   Carboxypeptidase A4 promotes proliferation and stem cell characteristics of hepatocellular carcinoma
   Int J Exp Pathol (2019) 100, 133-138. PubMed  Europe PubMed DOI
2016
10. He,J., Chen,D.L., Samocha-Bonet,D., Gillinder,K.R., Barclay,J.L., Magor,G.W., Perkins,A.C., Greenfield,J.R., Yang,G. and Whitehead,J.P.
    Fibroblast growth factor-1 (FGF-1) promotes adipogenesis by downregulation of carboxypeptidase A4 (CPA4) - a negative regulator of adipogenesis implicated in the modulation of local and systemic insulin sensitivity
    Growth Factors (2016) 34, 210-216. PubMed  Europe PubMed DOI
2015
11. Reytor,M.L., Reverter,D., Trejo,S., de Los Angeles Chavez,M., Aviles,F.X. and del Rivero,M.A.
    203 The crystal structure of a tri domain BPTI Kunitz inhibitor in complex with human carboxypeptidase A4 revealed a novel and non canonical inhibition mechanism
    J Biomol Struct Dyn (2015) 33 Suppl 1, 136-137. PubMed  Europe PubMed DOI  S
2013
12. Alonso Del Rivero,M., Reytor,M.L., Trejo,S.A., Chavez,M.A., Aviles,F.X. and Reverter,D.
    A noncanonical mechanism of carboxypeptidase inhibition revealed by the crystal structure of the tri-Kunitz SmCI in complex with human CPA4
    Structure (2013) 21, 1118-1126. PubMed  Europe PubMed DOI  S
2012
13. Fricker,L.D. and Gomis-Ruth,F.X.
    Carboxypeptidase A4
    [ISSN:978-0-12-407744-7] (2012) 3, 1307-1310. DOI
2010
14. Tanco,S., Zhang,X., Morano,C., Aviles,F.X., Lorenzo,J. and Fricker,L.D.
    Characterization of the substrate specificity of human carboxypeptidase A4 and implications for a role in extracellular peptide processing
    J Biol Chem (2010) 285, 18385-18396. PubMed  Europe PubMed DOI  P
15. Van Damme,P., Staes,A., Bronsoms,S., Helsens,K., Colaert,N., Timmerman,E., Aviles,F.X., Vandekerckhove,J. and Gevaert,K.
    Complementary positional proteomics for screening substrates of endo- and exoproteases
    Nat Methods (2010) 7, 512-515. PubMed  Europe PubMed DOI  P
2009
16. Ross,P.L., Cheng,I., Liu,X., Cicek,M.S., Carroll,P.R., Casey,G. and Witte,J.S.
    Carboxypeptidase 4 gene variants and early-onset intermediate-to-high risk prostate cancer
    BMC Cancer (2009) 9, 69-69. PubMed  Europe PubMed DOI  PMC  EPMC  M
2007
17. Bayes,A., Fernandez,D., Sola,M., Marrero,A., Garcia-Pique,S., Aviles,F.X., Vendrell,J. and Gomis-Ruth,F.X.
    Caught after the Act: a human A-type metallocarboxypeptidase in a product complex with a cleaved hexapeptide
    Biochemistry (2007) 46, 6921-6930. PubMed  Europe PubMed DOI  S
2005
18. [YEAR:9-8-2005]Garcia-Castellanos,R., Bonet-Figueredo,R., Pallares,I., Ventura,S., Aviles,F.X., Vendrell,J. and Gomis-Ruth,F.X.
    Detailed molecular comparison between the inhibition mode of A/B-type carboxypeptidases in the zymogen state and by the endogenous inhibitor latexin
    Cell Mol Life Sci (9-8-2005) 62, 1996-2014. PubMed  Europe PubMed DOI
19. [YEAR:15-3-2005]Pallares,I., Bonet,R., Garcia-Castellanos,R., Ventura,S., Aviles,F.X., Vendrell,J. and Gomis-Ruth,F.X.
    Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin
    Proc Natl Acad Sci U S A (15-3-2005) 102, 3978-3983. PubMed  Europe PubMed DOI  PMC  EPMC  S
2003
20. Bentley,L., Nakabayashi,K., Monk,D., Beechey,C., Peters,J., Birjandi,Z., Khayat,F.E., Patel,M., Preece,M.A., Stanier,P., Scherer,S.W. and Moore,G.E.
    The imprinted region on human chromosome 7q32 extends to the carboxypeptidase A gene cluster: an imprinted candidate for Silver-Russell syndrome
    J Med Genet (2003) 40, 249-256. PubMed  Europe PubMed  PMC  EPMC
21. Kayashima,T., Yamasaki,K., Yamada,T., Sakai,H., Miwa,N., Ohta,T., Yoshiura,K., Matsumoto,N., Nakane,Y., Kanetake,H., Ishino,F., Niikawa,N. and Kishino,T.
    The novel imprinted carboxypeptidase A4 gene ( CPA4) in the 7q32 imprinting domain
    Hum Genet (2003) 112, 220-226. PubMed  Europe PubMed DOI
1999
22. [YEAR:15-6-1999]Huang,H., Reed,C.P., Zhang,J.S., Shridhar,V., Wang,L. and Smith,D.I.
    Carboxypeptidase A3 (CPA3): a novel gene highly induced by histone deacetylase inhibitors during differentiation of prostate epithelial cancer cells
    Cancer Res (15-6-1999) 59, 2981-2988. PubMed  Europe PubMed