Literature for peptidase M13.008: neprilysin-2
(Topics flags: R Splicing, I Inhibitor, K Knockout, P Specificity, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)
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Ul-Haq,Z., Usmani,S., Iqbal,S. and Zia,S.R.
In silico based investigation of dynamic variations in neprilysin (NEP and NEP2) proteins for extracting the point of specificity
Mol Biosyst12, 1024-1036. PubMed Europe PubMed DOI P -
Marr,R.A. and Hafez,D.M.
Amyloid-beta and Alzheimer's disease: the role of neprilysin-2 in amyloid-beta clearance
Front Aging Neurosci6, 187-187. PubMed Europe PubMed DOI -
Takamatsu,K., Ikeda,T., Haruta,M., Matsumura,K., Ogi,Y., Nakagata,N., Uchino,M., Ando,Y., Nishimura,Y. and Senju,S.
Degradation of amyloid beta by human induced pluripotent stem cell-derived macrophages expressing neprilysin-2
Stem Cell Res13, 442-453. PubMed Europe PubMed DOI -
Huang,J.Y., Hafez,D.M., James,B.D., Bennett,D.A. and Marr,R.A.
Altered NEP2 expression and activity in mild cognitive impairment and Alzheimer's disease
J Alzheimers Dis28, 433-441. PubMed Europe PubMed DOI -
Marr,R.A.
Neprilysin-2
[ISSN:978-0-12-407744-7]3, 620-624. DOI -
Hafez,D., Huang,J.Y., Huynh,A.M., Valtierra,S., Rockenstein,E., Bruno,A.M., Lu,B., Desgroseillers,L., Masliah,E. and Marr,R.A.
Neprilysin-2 is an important beta-amyloid degrading enzyme
Am J Pathol178, 306-312. PubMed Europe PubMed DOI K -
Marr,R.A. and Spencer,B.J.
NEP-like endopeptidases and Alzheimer's disease [corrected]
Curr Alzheimer Res7, 223-229. PubMed Europe PubMed DOI I -
Bland,N.D., Robinson,P., Thomas,J.E., Shirras,A.D., Turner,A.J. and Isaac,R.E.
Locomotor and geotactic behavior of Drosophila melanogaster over-expressing neprilysin 2
Peptides30, 571-574. PubMed Europe PubMed DOI -
Huang,J.Y., Bruno,A.M., Patel,C.A., Huynh,A.M., Philibert,K.D., Glucksman,M.J. and Marr,R.A.
Human membrane metallo-endopeptidase-like protein degrades both beta-amyloid 42 and beta-amyloid 40
Neuroscience155, 258-262. PubMed Europe PubMed DOI R -
Oh-hashi,K., Ohkubo,K., Shizu,K., Fukuda,H., Hirata,Y. and Kiuchi,K.
Biosynthesis, processing, trafficking, and enzymatic activity of mouse neprilysin 2
Mol Cell Biochem313, 103-111. PubMed Europe PubMed DOI -
Whyteside,A.R. and Turner,A.J.
Human neprilysin-2 (NEP2) and NEP display distinct subcellular localisations and substrate preferences
FEBS Lett582, 2382-2386. PubMed Europe PubMed DOI -
[YEAR:1-8-2005]Voisin,S. and Ouimet,T.
The ultimate tryptophan residue of neprilysin 2 is not involved in protein maturation and enzymatic activity
Biochem Biophys Res Commun335, 356-360. PubMed Europe PubMed DOI -
Carpentier,M., Desgroseillers,L. and Boileau,G.
Neprilysin-2
[ISSN:0-12-079610-4]2, 426-429. V -
Carpentier,M., Guillemette,C., Bailey,J.L., Boileau,G., Jeannotte,L., Desgroseillers,L. and Charron,J.
Reduced fertility in male mice deficient in the zinc metallopeptidase NL1
Mol Cell Biol24, 4428-4437. PubMed Europe PubMed DOI K -
Ouimet,T.
Neprilysin 2: a novel messenger peptide-inactivating metalloprotease
Protein Pept Lett11, 479-489. PubMed Europe PubMed DOI -
[YEAR:4-8-2004]Voisin,S., Rognan,D., Gros,C. and Ouimet,T.
A three-dimensional model of the neprilysin 2 active site based on the X-ray structure of neprilysin. Identification of residues involved in substrate hydrolysis and inhibitor binding of neprilysin 2
J Biol Chem279, 46172-46181. PubMed Europe PubMed DOI -
Carpentier,M., Marcinkiewicz,M., Boileau,G. and Desgroseillers,L.
The neuropeptide-degrading enzyme NL1 is expressed in specific neurons of mouse brain
Peptides24, 1083-1091. PubMed Europe PubMed DOI -
Facchinetti,P., Rose,C., Schwartz,J.C. and Ouimet,T.
Ontogeny, regional and cellular distribution of the novel metalloprotease neprilysin 2 in the rat: a comparison with neprilysin and endothelin-converting enzyme-1
Neuroscience118, 627-639. PubMed Europe PubMed DOI -
[YEAR:1-5-2002]Rose,C., Voisin,S., Gros,C., Schwartz,J.C. and Ouimet,T.
Cell-specific activity of neprilysin 2 isoforms and enzymic specificity compared with neprilysin
Biochem J363, 697-705. PubMed Europe PubMed DOI -
Bonvouloir,N., Lemieux,N., Crine,P., Boileau,G. and Desgroseillers,L.
Molecular cloning, tissue distribution, and chromosomal localization of MMEL2, a gene coding for a novel human member of the neutral endopeptidase-24.11 family
DNA Cell Biol20, 493-498. PubMed Europe PubMed DOI -
[YEAR:6-7-2001]Raharjo,S.B., Emoto,N., Ikeda,K., Sato,R., Yokoyama,M. and Matsuo,M.
Alternative splicing regulates the endoplasmic reticulum localization or secretion of soluble secreted endopeptidase
J Biol Chem276, 25612-25620. PubMed Europe PubMed DOI R -
[YEAR:15-4-2000]Ghaddar,G., Ruchon,A.F., Carpentier,M., Marcinkiewicz,M., Seidah,N.G., Crine,P., Desgroseillers,L. and Boileau,G.
Molecular cloning and biochemical characterization of a new mouse testis soluble-zinc-metallopeptidase of the neprilysin family
Biochem J347, 419-429. PubMed Europe PubMed DOI -
[YEAR:19-5-2000]Ouimet,T., Facchinetti,P., Rose,C., Bonhomme,M.C., Gros,C., Schwartz,J.C. and Tanja,O.
Neprilysin II: A putative novel metalloprotease and its isoforms in CNS and testis
Biochem Biophys Res Commun271, 565-570. PubMed Europe PubMed DOI -
[YEAR:5-11-1999]Ikeda,K., Emoto,N., Raharjo,S.B., Nurhantari,Y., Saiki,K., Yokoyama,M. and Matsuo,M.
Molecular identification and characterization of novel membrane-bound metalloprotease, the soluble secreted form of which hydrolyzes a variety of vasoactive peptides
J Biol Chem274, 32469-32477. PubMed Europe PubMed DOI I
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