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Literature for peptidase M13.003: endothelin-converting enzyme 2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, R Splicing, K Knockout, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Gupta,A., Gomes,I., Sierra,S., Osman,A. and Devi,L.A.<br>Endothelin-converting enzyme 2 regulates kappa opioid receptor trafficking and function<br>J Pharmacol Exp Ther (2025) 392, 103750-103750. PubMed  Europe PubMed DOI
    2. 2017
  2. Miners,J.S. and Love,S.<br>Endothelin-converting enzymes degrade alpha-synuclein and are reduced in dementia with Lewy bodies<br>J Neurochem (2017) 141, 275-286. PubMed  Europe PubMed DOI
    3. 2015
  3. Gupta,A., Fujita,W., Gomes,I., Bobeck,E. and Devi,L.A.<br>Endothelin-converting enzyme 2 differentially regulates opioid receptor activity<br>Br J Pharmacol (2015) 172, 704-719. PubMed  Europe PubMed DOI  I
    4. 2014
  4. Gupta,A., Gomes,I., Wardman,J. and Devi,L.A.<br>Opioid receptor function is regulated by post-endocytic peptide processing<br>J Biol Chem (2014) 289, 19613-19626. PubMed  Europe PubMed DOI
    5. 2012
  5. Devi,L.A. and Miller,L.K.<br>Endothelin-converting enzyme 2<br>[ISSN:978-0-12-407744-7] (2012) 3, 632-635. DOI
    6. 2010
  6. Ouimet,T., Orng,S.V., Poras,H., Gagnidze,K., Devi,L.A., Fournie-Zaluski,M.C. and Roques,B.P.<br>Identification of an endothelin-converting enzyme-2-specific fluorigenic substrate and development of an in vitro and ex vivo enzymatic assay<br>J Biol Chem (2010) 285, 34390-34400. PubMed  Europe PubMed DOI  A  I
    7. 2009
  7. Palmer,J.C., Baig,S., Kehoe,P.G. and Love,S.<br>Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta<br>Am J Pathol (2009) 175, 262-270. PubMed  Europe PubMed DOI  PMC  EPMC
  8. Tempel,W., Wu,H., Dombrovsky,L., Zeng,H., Loppnau,P., Zhu,H., Plotnikov,A.N. and Bochkarev,A.<br>An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene<br>Proteins (2009) 74, 789-793. PubMed  Europe PubMed DOI  S
    9. 2008
  9. Gagnidze,K., Sachchidanand, Rozenfeld,R., Mezei,M., Zhou,M.M. and Devi,L.A.<br>Homology modeling and site-directed mutagenesis to identify selective inhibitors of endothelin-converting enzyme-2<br>J Med Chem (2008) 51, 3378-3387. PubMed  Europe PubMed DOI  PMC  EPMC  I
    10. 2007
  10. Rodriguiz,R.M., Gadnidze,K., Ragnauth,A., Dorr,N., Yanagisawa,M., Wetsel,W.C. and Devi,L.A.<br>Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory<br>Genes Brain Behav (2007) 7, 418-426. PubMed  Europe PubMed DOI  K
    11. 2004
  11. Ahn,K.<br>Endothelin-converting enzyme 2<br>[ISSN:0-12-079610-4] (2004) 2, 434-436.  V
  12. Pan,H., Mzhavia,N. and Devi,L.A.<br>Endothelin converting enzyme-2: a processing enzyme involved in the generation of novel neuropeptides<br>Protein Pept Lett (2004) 11, 461-469. PubMed  Europe PubMed DOI
    13. 2003
  13. [YEAR:25-4-2003]Mzhavia,N., Pan,H., Che,F.Y., Fricker,L.D. and Devi,L.A.<br>Characterization of endothelin-converting enzyme-2. Implication for a role in the nonclassical processing of regulatory peptides<br>J Biol Chem (25-4-2003) 278, 14704-14711. PubMed  Europe PubMed DOI
    14. 2002
  14. [YEAR:26-4-2002]Ikeda,S., Emoto,N., Alimsardjono,H., Yokoyama,M. and Matsuo,M.<br>Molecular isolation and characterization of novel four subisoforms of ECE-2<br>Biochem Biophys Res Commun (26-4-2002) 293, 421-426. PubMed  Europe PubMed DOI  R
    15. 2000
  15. Davenport,A.P. and Kuc,R.E.<br>Cellular expression of isoforms of endothelin-converting enzyme-1 (ECE-1c, ECE-1b and ECE-1a) and endothelin-converting enzyme-2<br>J Cardiovasc Pharmacol (2000) 36, S12-S14. PubMed  Europe PubMed
  16. Yanagisawa,H., Hammer,R.E., Richardson,J.A., Emoto,N., Williams,S.C., Takeda,S., Clouthier,D.E. and Yanagisawa,M.<br>Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development<br>J Clin Invest (2000) 105, 1373-1382. PubMed  Europe PubMed DOI  PMC  EPMC  K
    17. 1996
  17. Turner,A.J. and Murphy,L.J.<br>Molecular pharmacology of endothelin converting enzymes<br>Biochem Pharmacol (1996) 51, 91-102. PubMed  Europe PubMed DOI
    18. 1995
  18. Emoto,N. and Yanagisawa,M.<br>Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon-sensitive metalloprotease with acidic pH optimum<br>J Biol Chem (1995) 270, 15262-15268. PubMed  Europe PubMed DOI  I
    19. 1991
  19. [YEAR:31-7-1991]Matsumura,Y., Ikegawa,R., Tsukahara,Y., Takaoka,M. and Morimoto,S.<br>N-Ethylmaleimide differentiates endothelin converting activity by two types of metalloproteinases derived from vascular endothelial cells<br>Biochem Biophys Res Commun (31-7-1991) 178, 531-538. PubMed  Europe PubMed DOI  I
    20. 1990
  20. Wu-Wong,J.R., Budzik,G.P., Devine,E.M. and Opgenorth,T.J.<br>Characterization of endothelin converting enzyme in rat lung<br>Biochem Biophys Res Commun (1990) 171, 1291-1296. PubMed  Europe PubMed

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