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Literature for peptidase M12.016: vertebrate tolloid-like 1 protein

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, M Mutation, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Agam,N., Dolgin,V., Star,A., Freund,O., Jean,M.M., Safran,A., Poleg,T., Zahger,D. and Birk,O.S.
    Mitral Valve Prolapse Caused by TLL1 Gain-of-Function Mutation
    Can J Cardiol PubMed  Europe PubMed DOI
    2. 2021
  2. Wang,J., Xie,X., Muench,N.A., Massoudi,D., Xu,C., Greenspan,D.S. and Feng,J.Q.
    Proteinase bone morphogenetic protein 1, but not tolloid-like 1, plays a dominant role in maintaining periodontal homeostasis
    J Periodontol92, 1018-1029. PubMed  Europe PubMed DOI
    3. 2020
  3. Carlantoni,C., Allanki,S., Kontarakis,Z., Rossi,A., Piesker,J., Gunther,S. and Stainier,D.Y.R.
    Tie1 regulates zebrafish cardiac morphogenesis through Tolloid-like 1 expression
    Dev Biol469, 54-67. PubMed  Europe PubMed DOI
    4. 2019
  4. Sieron,L., Lesiak,M., Schisler,I., Drzazga,Z., Fertala,A. and Sieron,A.L.
    Functional and structural studies of tolloid-like 1 (TLL1) mutants associated with atrial-septal defect 6 (ASD6)
    Biosci Rep39, BSR20180270-BSR20180270. PubMed  Europe PubMed DOI  M
    5. 2016
  5. Bayley,C.P., Ruiz Nivia,H.D., Dajani,R., Jowitt,T.A., Collins,R.F., Rada,H., Bird,L.E. and Baldock,C.
    Diversity between mammalian tolloid proteinases: oligomerisation and non-catalytic domains influence activity and specificity
    Sci Rep6, 21456-21456. PubMed  Europe PubMed DOI
  6. Muir,A.M., Massoudi,D., Nguyen,N., Keene,D.R., Lee,S.J., Birk,D.E., Davidson,J.M., Marinkovich,M.P. and Greenspan,D.S.
    BMP1-like proteinases are essential to the structure and wound healing of skin
    Matrix Biol56, 114-131. PubMed  Europe PubMed DOI  K
    7. 2015
  7. Vadon-Le Goff,S., Hulmes,D.J. and Moali,C.
    BMP-1/tolloid-like proteinases synchronize matrix assembly with growth factor activation to promote morphogenesis and tissue remodeling
    Matrix Biol44-46C, 14-23. PubMed  Europe PubMed DOI  V
    8. 2014
  8. Muir,A.M., Ren,Y., Butz,D.H., Davis,N.A., Blank,R.D., Birk,D.E., Lee,S.J., Rowe,D., Feng,J.Q. and Greenspan,D.S.
    Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice
    Hum Mol Genet23, 3085-3101. PubMed  Europe PubMed DOI  K
    9. 2012
  9. Kessler,E.
    Mammalian tolloid-like peptidases
    [ISSN:978-0-12-407744-7]3, 936-942. DOI
    10. 2011
  10. Okada,H.
    Tolloid-like proteinases orchestrate extracellular matrix formation
    J Am Soc Nephrol22, 588-589. PubMed  Europe PubMed DOI
    11. 2010
  11. Berry,R., Jowitt,T.A., Garrigue-Antar,L., Kadler,K.E. and Baldock,C.
    Structural and functional evidence for a substrate exclusion mechanism in mammalian tolloid like-1 (TLL-1) proteinase
    FEBS Lett584, 657-661. PubMed  Europe PubMed DOI
    12. 2009
  12. Stanczak,P., Witecka,J., Szydlo,A., Gutmajster,E., Lisik,M., Augusciak-Duma,A., Tarnowski,M., Czekaj,T., Czekaj,H. and Sieron,A.L.
    Mutations in mammalian tolloid-like 1 gene detected in adult patients with ASD
    Eur J Hum Genet17, 344-351. PubMed  Europe PubMed DOI  M
    13. 2008
  13. Mac Sweeney,A., Gil-Parrado,S., Vinzenz,D., Bernardi,A., Hein,A., Bodendorf,U., Erbel,P., Logel,C. and Gerhartz,B.
    Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases
    J Mol Biol384, 228-239. PubMed  Europe PubMed DOI  S
    14. 2006
  14. Ge,G. and Greenspan,D.S.
    Developmental roles of the BMP1/TLD metalloproteinases
    Birth Defects Res C Embryo Today78, 47-68. PubMed  Europe PubMed DOI  V
  15. [YEAR:28-2-2006]Ge,G., Zhang,Y., Steiglitz,B.M. and Greenspan,D.S.
    Mammalian tolloid-like 1 binds procollagen C-proteinase enhancer protein 1 and differs from bone morphogenetic protein 1 in the functional roles of homologous protein domains
    J Biol Chem281, 10786-10798. PubMed  Europe PubMed DOI
    16. 2004
  16. [YEAR:1-10-2004]Ge,G., Seo,N.S., Liang,X., Hopkins,D.R., Hook,M. and Greenspan,D.S.
    Bone morphogenetic protein-1/tolloid-related metalloproteinases process osteoglycin and enhance its ability to regulate collagen fibrillogenesis
    J Biol Chem279, 41626-41633. PubMed  Europe PubMed DOI
  17. Greenspan,D.S.
    Mammalian tolloid-like peptidases
    [ISSN:0-12-079610-4]2, 621-623.  V
    18. 2003
  18. Pappano,W.N., Steiglitz,B.M., Scott,I.C., Keene,D.R. and Greenspan,D.S.
    Use of Bmp1/Tll1 doubly homozygous null mice and proteomics to identify and validate in vivo substrates of bone morphogenetic protein 1/tolloid-like metalloproteinases
    Mol Cell Biol23, 4428-4438. PubMed  Europe PubMed DOI  K
  19. [YEAR:23-12-2003]Wolfman,N.M., McPherron,A.C., Pappano,W.N., Davies,M.V., Song,K., Tomkinson,K.N., Wright,J.F., Zhao,L., Sebald,S.M., Greenspan,D.S. and Lee,S.J.
    Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases
    Proc Natl Acad Sci U S A100, 15842-15846. PubMed  Europe PubMed DOI
    20. 2001
  20. [YEAR:22-6-2001]Uzel,M.I., Scott,I.C., Babakhanlou-Chase,H., Palamakumbura,A.H., Pappano,W.N., Hong,H.H., Greenspan,D.S. and Trackman,P.C.
    Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures
    J Biol Chem276, 22537-22543. PubMed  Europe PubMed DOI
    21. 2000
  21. [YEAR:29-9-2000]Scott,I.C., Imamura,Y., Pappano,W.N., Troedel,J.M., Recklies,A.D., Roughley,P.J. and Greenspan,D.S.
    Bone morphogenetic protein-1 processes probiglycan
    J Biol Chem275, 30504-30511. PubMed  Europe PubMed DOI
    22. 1999
  22. Clark,T.G., Conway,S.J., Scott,I.C., Labosky,P.A., Winnier,G., Bundy,J., Hogan,B.L. and Greenspan,D.S.
    The mammalian tolloid-like 1 gene, Tll1, is necessary for normal septation and positioning of the heart
    Development126, 2631-2642. PubMed  Europe PubMed  K
  23. Connors,S.A., Trout,J., Ekker,M. and Mullins,M.C.
    The role of tolloid/mini fin in dorsoventral pattern formation of the zebrafish embryo
    Development126, 3119-3130. PubMed  Europe PubMed
  24. [YEAR:15-9-1999]Scott,I.C., Blitz,I.L., Pappano,W.N., Imamura,Y., Clark,T.G., Steiglitz,B.M., Thomas,C.L., Maas,S.A., Takahara,K., Cho,K.W. and Greenspan,D.S.
    Mammalian BMP-1/tolloid-related metalloproteinases, including novel family member mammalian tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis
    Dev Biol213, 283-300. PubMed  Europe PubMed DOI
  25. Scott,I.C., Clark,T.G., Takahara,K., Hoffman,G.G., Eddy,R.L., Haley,L.L., Shows,T.B. and Greenspan,D.S.
    Assignment of TLL1 and TLL2, which encode human BMP-1/Tolloid-related metalloproteases, to chromosomes 4q32 - >q33 and 10q23 - >q24 and assignment of murine Tll2 to chromosome 19
    Cytogenet Cell Genet86, 64-65. PubMed  Europe PubMed
    26. 1997
  26. Blader,P., Rastegar,S., Fischer,N. and Strahle,U.
    Cleavage of the BMP-4 antagonist chordin by zebrafish tolloid
    Science278, 1937-1940. PubMed  Europe PubMed DOI
  27. [YEAR:25-7-1997]Lee,S., Solow-Cordero,D.E., Kessler,E., Takahara,K. and Greenspan,D.S.
    Transforming growth factor-beta regulation of bone morphogenetic protein-1/procollagen C-proteinase and related proteins in fibrogenic cells and keratinocytes
    J Biol Chem272, 19059-19066. PubMed  Europe PubMed DOI
    28. 1996
  28. [YEAR:1-6-1996]Takahara,K., Brevard,R., Hoffman,G.G., Suzuki,N. and Greenspan,D.S.
    Characterization of a novel gene product (mammalian tolloid-like) with high sequence similarity to mammalian tolloid/bone morphogenetic protein-1
    Genomics34, 157-165. PubMed  Europe PubMed DOI

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