Literature for peptidase M12.005: procollagen C-peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, P Specificity, K Knockout, V Review, M Mutation, I Inhibitor, R Splicing. To select only the references relevant to a single topic, click the link above. See explanation.)

2025

Wert,K., Jentsch,J., Gallwas,J. and Grundker,C. BMP1 Appears to be Involved in GPER1-mediated Progression and Tamoxifen Resistance of Luminal A Breast Cancer Cells Cancer Genomics Proteomics (2025) 22, 900-911. PubMed Europe PubMed DOI PMC EPMC

2024

Wan,S., Liu,X., Sun,R., Liu,H., Jiang,J. and Wu,B. Activated hepatic stellate cell-derived Bmp-1 induces liver fibrosis via mediating hepatocyte epithelial-mesenchymal transition Cell Death Dis (2024) 15, 41-41. PubMed Europe PubMed DOI PMC EPMC

2023

Donovan,M.K.R., Huang,Y., Blume,J.E., Wang,J., Hornburg,D., Ferdosi,S., Mohtashemi,I., Kim,S., Ko,M., Benz,R.W., Platt,T.L., Batzoglou,S., Diaz,L.A., Farokhzad,O.C. and Siddiqui,A. Functionally distinct BMP1 isoforms show an opposite pattern of abundance in plasma from non-small cell lung cancer subjects and controls PLoS ONE (2023) 18, e0282821-e0282821. PubMed Europe PubMed DOI PMC EPMC
Miranda,P., Mirisis,A.A., Kukushkin,N.V. and Carew,T.J. Pattern detection in the TGFbeta cascade controls the induction of long-term synaptic plasticity Proc Natl Acad Sci U S A (2023) 120, e2300595120-e2300595120. PubMed Europe PubMed DOI PMC EPMC
Vadon-Le Goff,S., Tessier,A., Napoli,M., Dieryckx,C., Bauer,J., Dussoyer,M., Lagoutte,P., Peyronnel,C., Essayan,L., Kleiser,S., Tueni,N., Bettler,E., Mariano,N., Errazuriz-Cerda,E., Fruchart Gaillard,C., Ruggiero,F., Becker-Pauly,C., Allain,J.M., Bruckner-Tuderman,L., Nystrom,A. and Moali,C. Identification of PCPE-2 as the endogenous specific inhibitor of human BMP-1/tolloid-like proteinases Nat Commun (2023) 14, 8020-8020. PubMed Europe PubMed DOI PMC EPMC

2022

Ma,H.Y., N'Diaye,E.N., Caplazi,P., Huang,Z., Arlantico,A., Jeet,S., Wong,A., Brightbill,H.D., Li,Q., Wong,W.R., Sandoval,W., Tam,L., Newman,R., Roose-Girma,M. and Ding,N. BMP1 is not required for lung fibrosis in mice Sci Rep (2022) 12, 5466-5466. PubMed Europe PubMed DOI PMC EPMC
Sharma,U., Vadon-Le Goff,S., Harlos,K., Zhao,Y., Mariano,N., Bijakowski,C., Bourhis,J.M., Moali,C., Hulmes,D.J.S. and Aghajari,N. Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1) Sci Rep (2022) 12, 14850-14850. PubMed Europe PubMed DOI PMC EPMC
Vukicevic,S., Colliva,A., Kufner,V., Martinelli,V., Moimas,S., Vodret,S., Rumenovic,V., Milosevic,M., Brkljacic,B., Delic-Brkljacic,D., Correa,R., Giacca,M., Maglione,M., Bordukalo-Niksic,T., Dumic-Cule,I. and Zacchigna,S. Bone morphogenetic protein 1.3 inhibition decreases scar formation and supports cardiomyocyte survival after myocardial infarction Nat Commun (2022) 13, 81-81. PubMed Europe PubMed DOI PMC EPMC
Zhou,Y., Xu,S., Sun,Q. and Dong,Y. An Analysis of BMP1 Associated with m6A Modification and Immune Infiltration in Pancancer Dis Markers (2022) 2022, 7899961-7899961. PubMed Europe PubMed DOI PMC EPMC

2021

Vantourout,J.C., Mason,A.M., Yuen,J., Simpson,G.L., Evindar,G., Kuai,L., Hobbs,M., Edgar,E., Needle,S., Bai,X., Wilson,S., Scott-Stevens,P., Traylen,W., Lambert,K., Young,N., Bunally,S., Summerfield,S.G., Snell,R., Lad,R., Shi,E., Skinner,S., Shewchuk,L., Watson,A.J.B., Chung,C.W., Pal,S., Holt,D.A., Kallander,L.S., Prendergast,J., Rivera,K., Washburn,D.G., Harpel,M.R., Arico-Muendel,C. and Isidro-Llobet,A. In Vivo Half-Life Extension of BMP1/TLL Metalloproteinase Inhibitors Using Small-Molecule Human Serum Albumin Binders Bioconjug Chem (2021) 32, 279-289. PubMed Europe PubMed DOI
Wang,J., Xie,X., Muench,N.A., Massoudi,D., Xu,C., Greenspan,D.S. and Feng,J.Q. Proteinase bone morphogenetic protein 1, but not tolloid-like 1, plays a dominant role in maintaining periodontal homeostasis J Periodontol (2021) 92, 1018-1029. PubMed Europe PubMed DOI

2020

Eshed-Eisenbach,Y., Devaux,J., Vainshtein,A., Golani,O., Lee,S.J., Feinberg,K., Sukhanov,N., Greenspan,D.S., Susuki,K., Rasband,M.N. and Peles,E. Precise Spatiotemporal Control of Nodal Na(+) Channel Clustering by Bone Morphogenetic Protein-1/Tolloid-like Proteinases Neuron (2020) 106, 806-815. PubMed Europe PubMed DOI
N'Diaye,E.N., Cook,R., Wang,H., Wu,P., LaCanna,R., Wu,C., Ye,Z., Seshasayee,D., Hazen,M., Lin,W., Tyagi,T., Hotzel,I., Tam,L., Newman,R., Roose-Girma,M., Wolters,P.J. and Ding,N. Extracellular BMP1 is the major proteinase for C-terminal proteolysis of type I procollagen in lung fibroblasts Am J Physiol Cell Physiol (2020) PubMed Europe PubMed DOI K
Rafi,J.H., Jafar,T., Pathan,M.T., Reza,R., Islam,S., Sourna,I.J., Alam,R., Samad,A. and Ahammad,F. High expression of bone morphogenetic protein 1 (BMP1) is associated with a poor survival rate in human gastric cancer, a dataset approaches Genomics (2020) PubMed Europe PubMed DOI
Strom,T.B., Bjune,K. and Leren,T.P. Bone morphogenetic protein 1 cleaves the linker region between ligand-binding repeats 4 and 5 of the LDL receptor and makes the LDL receptor non-functional Hum Mol Genet (2020) 29, 1229-1238. PubMed Europe PubMed DOI I

2019

Saunders,J.T. and Schwarzbauer,J.E. Fibronectin matrix as a scaffold for procollagen proteinase binding and collagen processing Mol Biol Cell (2019) 30, 2218-2226. PubMed Europe PubMed DOI
Zhu,Q., Guo,W., Zhang,S., Feng,Y., Wang,X., Zhou,L. and Huang,G.R. Synergistic effect of PCPE1 and sFRP2 on the processing of procollagens via BMP1 FEBS Lett (2019) 593, 119-127. PubMed Europe PubMed DOI

2018

Kallander,L.S., Washburn,D., Hilfiker,M.A., Eidam,H.S., Lawhorn,B.G., Prendergast,J., Fox,R., Dowdell,S., Manns,S., Hoang,T., Zhao,S., Ye,G., Hammond,M., Holt,D.A., Roethke,T., Hong,X., Reid,R.A., Gampe,R., Zhang,H., Diaz,E., Rendina,A.R., Quinn,A.M. and Willette,B. Reverse hydroxamate inhibitors of bone morphogenetic protein 1 ACS Med Chem Lett (2018) 9, 736-740. PubMed Europe PubMed DOI PMC EPMC I
Lockhart-Cairns,M.P. and Baldock,C. Unraveling the mechanism of procollagen C-proteinase enhancer Structure (2018) 26, 1299-1301. PubMed Europe PubMed DOI
Pulido,D., Sharma,U., Vadon-Le Goff,S., Hussain,S.A., Cordes,S., Mariano,N., Bettler,E., Moali,C., Aghajari,N., Hohenester,E. and Hulmes,D.J.S. Structural basis for the acceleration of procollagen processing by procollagen C-proteinase enhancer-1 Structure (2018) 26, 1384-1392. PubMed Europe PubMed DOI
Talantikite,M., Lecorche,P., Beau,F., Damour,O., Becker-Pauly,C., Ho,W.B., Dive,V., Vadon-Le Goff,S. and Moali,C. Inhibitors of BMP-1/tolloid-like proteinases: efficacy, selectivity and cellular toxicity FEBS Open Bio (2018) 8, 2011-2021. PubMed Europe PubMed DOI PMC EPMC I

2017

Khazaei,A., Sarmasti,N., Seyf,J.Y., Rostami,Z. and Zolfigol,M.A. QSAR study of the non-peptidic inhibitors of procollagen C-proteinase based on multiple linear regression, principle component regression, and partial least squares Arab J Chem (2017) 10, 801-810. DOI I
Sangsin,A., Kuptanon,C., Srichomthong,C., Pongpanich,M., Suphapeetiporn,K. and Shotelersuk,V. Two novel compound heterozygous BMP1 mutations in a patient with osteogenesis imperfecta: a case report BMC Med Genet (2017) 18, 25-25. PubMed Europe PubMed DOI PMC EPMC M
Schneppenheim,J., Scharfenberg,F., Lucius,R., Becker-Pauly,C. and Arnold,P. Meprin beta and BMP-1 are differentially regulated by CaCl2 Cell Calcium (2017) 65, 8-13. PubMed Europe PubMed DOI

2016

Bayley,C.P., Ruiz Nivia,H.D., Dajani,R., Jowitt,T.A., Collins,R.F., Rada,H., Bird,L.E. and Baldock,C. Diversity between mammalian tolloid proteinases: oligomerisation and non-catalytic domains influence activity and specificity Sci Rep (2016) 6, 21456-21456. PubMed Europe PubMed DOI PMC EPMC
Hung,C.W., Koudelka,T., Anastasi,C., Becker,A., Moali,C. and Tholey,A. Characterization of post-translational modifications in full-length human BMP-1 confirms the presence of a rare vicinal disulfide linkage in the catalytic domain and highlights novel features of the EGF domain J Proteomics (2016) 138, 136-145. PubMed Europe PubMed DOI
Muir,A.M., Massoudi,D., Nguyen,N., Keene,D.R., Lee,S.J., Birk,D.E., Davidson,J.M., Marinkovich,M.P. and Greenspan,D.S. BMP1-like proteinases are essential to the structure and wound healing of skin Matrix Biol (2016) 56, 114-131. PubMed Europe PubMed DOI K
Troilo,H., Bayley,C.P., Barrett,A.L., Lockhart-Cairns,M.P., Jowitt,T.A. and Baldock,C. Mammalian tolloid proteinases: role in growth factor signalling FEBS Lett (2016) 590, 2398-2407. PubMed Europe PubMed DOI

2015

Syx,D., Guillemyn,B., Symoens,S., Sousa,A.B., Medeira,A., Whiteford,M., Hermanns-Le,T., Coucke,P.J., De Paepe,A. and Malfait,F. Defective proteolytic processing of fibrillar procollagens and prodecorin due to biallelic BMP1 mutations results in a severe, progressive form of osteogenesis imperfecta J Bone Miner Res (2015) 30, 1445-1456. PubMed Europe PubMed DOI M
Vadon-Le Goff,S., Hulmes,D.J. and Moali,C. BMP-1/tolloid-like proteinases synchronize matrix assembly with growth factor activation to promote morphogenesis and tissue remodeling Matrix Biol (2015) 44-46C, 14-23. PubMed Europe PubMed DOI V

2014

Muir,A.M., Ren,Y., Butz,D.H., Davis,N.A., Blank,R.D., Birk,D.E., Lee,S.J., Rowe,D., Feng,J.Q. and Greenspan,D.S. Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice Hum Mol Genet (2014) 23, 3085-3101. PubMed Europe PubMed DOI K
Valencia,M., Caparros-Martin,J.A., Sirerol-Piquer,M.S., Garcia-Verdugo,J.M., Martinez-Glez,V., Lapunzina,P., Temtamy,S., Aglan,M., Lund,A.M., Nikkels,P.G., Ruiz-Perez,V.L. and Ostergaard,E. Report of a newly indentified patient with mutations in BMP1 and underlying pathogenetic aspects Am J Med Genet A (2014) 164A, 1143-1150. PubMed Europe PubMed DOI M
Yang,R.T., Lim,G.L., Yee,C.T., Fuller,R.S. and Ritchie,H.H. Site specificity of DSP-PP cleavage by BMP1 Connect Tissue Res (2014) 55 Suppl 1, 142-145. PubMed Europe PubMed DOI P

2013

Bourhis,J.M., Vadon-Le Goff,S., Afrache,H., Mariano,N., Kronenberg,D., Thielens,N., Moali,C. and Hulmes,D.J. Procollagen C-proteinase enhancer grasps the stalk of the C-propeptide trimer to boost collagen precursor maturation Proc Natl Acad Sci U S A (2013) 110, 6394-6399. PubMed Europe PubMed DOI
De Robertis,E.M. and Colozza,G. Development: scaling to size by protease inhibition Curr Biol (2013) 23, R652-R654. PubMed Europe PubMed DOI
Inomata,H., Shibata,T., Haraguchi,T. and Sasai,Y. Scaling of dorsal-ventral patterning by embryo size-dependent degradation of Spemann's organizer signals Cell (2013) 153, 1296-1311. PubMed Europe PubMed DOI

2012

Asharani,P.V., Keupp,K., Semler,O., Wang,W., Li,Y., Thiele,H., Yigit,G., Pohl,E., Becker,J., Frommolt,P., Sonntag,C., Altmuller,J., Zimmermann,K., Greenspan,D.S., Akarsu,N.A., Netzer,C., Schonau,E., Wirth,R., Hammerschmidt,M., Nurnberg,P., Wollnik,B. and Carney,T.J. Attenuated BMP1 function compromises osteogenesis, leading to bone fragility in humans and zebrafish Am J Hum Genet (2012) 90, 661-674. PubMed Europe PubMed DOI PMC EPMC M
Kessler,E. Procollagen C-endopeptidase [ISSN:978-0-12-407744-7] (2012) 3, 916-932. DOI
Martinez-Glez,V., Valencia,M., Caparros-Martin,J.A., Aglan,M., Temtamy,S., Tenorio,J., Pulido,V., Lindert,U., Rohrbach,M., Eyre,D., Giunta,C., Lapunzina,P. and Ruiz-Perez,V.L. Identification of a mutation causing deficient BMP1/mTLD proteolytic activity in autosomal recessive osteogenesis imperfecta Hum Mutat (2012) 33, 343-350. PubMed Europe PubMed DOI M
Ritchie,H.H., Yee,C.T., Tang,X.N., Dong,Z. and Fuller,R.S. DSP-PP precursor protein cleavage by tolloid-related-1 protein and by bone morphogenetic protein-1 PLoS ONE (2012) 7, e41110-e41110. PubMed Europe PubMed DOI PMC EPMC
Turtle,E., Chow,N., Yang,C., Sosa,S., Bauer,U., Brenner,M., Solow-Cordero,D. and Ho,W.B. Design and synthesis of procollagen C-proteinase inhibitors Bioorg Med Chem Lett (2012) 22, 7397-7401. PubMed Europe PubMed DOI I
Zhu,Q., Prasad,M., Kong,H., Lu,Y., Sun,Y., Wang,X., Yamoah,A., Feng,J.Q. and Qin,C. Partial blocking of mouse DSPP processing by substitution of Gly(451)-Asp(452) bond suggests the presence of secondary cleavage site(s) Connect Tissue Res (2012) 53, 307-312. PubMed Europe PubMed DOI

2011

Grgurevic,L., Macek,B., Healy,D.R., Brault,A.L., Erjavec,I., Cipcic,A., Grgurevic,I., Rogic,D., Galesic,K., Brkljacic,J., Stern-Padovan,R., Paralkar,V.M. and Vukicevic,S. Circulating bone morphogenetic protein 1-3 isoform increases renal fibrosis J Am Soc Nephrol (2011) 22, 681-692. PubMed Europe PubMed DOI PMC EPMC
Grgurevic,L., Macek,B., Mercep,M., Jelic,M., Smoljanovic,T., Erjavec,I., Dumic-Cule,I., Prgomet,S., Durdevic,D., Vnuk,D., Lipar,M., Stejskal,M., Kufner,V., Brkljacic,J., Maticic,D. and Vukicevic,S. Bone morphogenetic protein (BMP)1-3 enhances bone repair Biochem Biophys Res Commun (2011) 408, 25-31. PubMed Europe PubMed DOI
Kim,B., Huang,G., Ho,W.B. and Greenspan,D.S. Bone morphogenetic protein-1 processes insulin-like growth factor-binding protein 3 J Biol Chem (2011) 286, 29014-29025. PubMed Europe PubMed DOI P
Peluso,C.E., Umulis,D., Kim,Y.J., O'Connor,M.B. and Serpe,M. Shaping BMP morphogen gradients through enzyme-substrate interactions Dev Cell (2011) 21, 375-383. PubMed Europe PubMed DOI
Tsuchiya,S., Simmer,J.P., Hu,J.C., Richardson,A.S., Yamakoshi,F. and Yamakoshi,Y. Astacin proteases cleave dentin sialophosphoprotein (Dspp) to generate dentin phosphoprotein (Dpp) J Bone Miner Res (2011) 26, 220-228. PubMed Europe PubMed DOI P
Vadon-Le Goff,S., Kronenberg,D., Bourhis,J.M., Bijakowski,C., Raynal,N., Ruggiero,F., Farndale,R.W., Stocker,W., Hulmes,D.J. and Moali,C. Procollagen C-proteinase enhancer stimulates procollagen processing by binding to the C-propeptide region only J Biol Chem (2011) 286, 38932-38938. PubMed Europe PubMed DOI

2010

Bekhouche,M., Kronenberg,D., Vadon-Le Goff,S., Bijakowski,C., Lim,N.H., Font,B., Kessler,E., Colige,A., Nagase,H., Murphy,G., Hulmes,D.J. and Moali,C. Role of the netrin-like domain of procollagen C-proteinase enhancer-1 in the control of metalloproteinase activity J Biol Chem (2010) 285, 15950-15959. PubMed Europe PubMed DOI
Maruhashi,T., Kii,I., Saito,M. and Kudo,A. Interaction between periostin and BMP-1 promotes proteolytic activation of lysyl oxidase J Biol Chem (2010) 285, 13294-13303. PubMed Europe PubMed DOI
von Marschall,Z. and Fisher,L.W. Dentin sialophosphoprotein (DSPP) is cleaved into its two natural dentin matrix products by three isoforms of bone morphogenetic protein-1 (BMP1) Matrix Biol (2010) 29, 295-303. PubMed Europe PubMed DOI
von Marschall,Z. and Fisher,L.W. Decorin is processed by three isoforms of bone morphogenetic protein-1 (BMP1) Biochem Biophys Res Commun (2010) 391, 1374-1378. PubMed Europe PubMed DOI PMC EPMC

2009

Berry,R., Jowitt,T.A., Ferrand,J., Roessle,M., Grossmann,J.G., Canty-Laird,E.G., Kammerer,R.A., Kadler,K.E. and Baldock,C. Role of dimerization and substrate exclusion in the regulation of bone morphogenetic protein-1 and mammalian tolloid Proc Natl Acad Sci U S A (2009) 106, 8561-8566. PubMed Europe PubMed DOI PMC EPMC R
Huang,G., Zhang,Y., Kim,B., Ge,G., Annis,D.S., Mosher,D.F. and Greenspan,D.S. Fibronectin binds and enhances the activity of bone morphogenetic protein 1 J Biol Chem (2009) 284, 25879-25888. PubMed Europe PubMed DOI PMC EPMC
Kronenberg,D., Vadon-Le Goff,S., Bourhis,J.M., Font,B., Eichenberger,D., Hulmes,D.J. and Moali,C. Strong cooperativity and loose geometry between CUB domains are the basis for procollagen C-proteinase enhancer activity J Biol Chem (2009) 284, 33437-33446. PubMed Europe PubMed DOI
Lee,H.X., Mendes,F.A., Plouhinec,J.L. and De Robertis,E.M. Enzymatic regulation of pattern: BMP4 binds CUB domains of Tolloids and inhibits proteinase activity Genes Dev (2009) 23, 2551-2562. PubMed Europe PubMed DOI A
Lesiak,M., Augusciak-Duma,A., Szydlo,A. and Sieron,A.L. Blocking angiogenesis with peptides that inhibit the activity of procollagen C-endopeptidase Pharmacol Rep (2009) 61, 468-476. PubMed Europe PubMed I

2008

Bailey,S., Fish,P.V., Billotte,S., Bordner,J., Greiling,D., James,K., McElroy,A., Mills,J.E., Reed,C. and Webster,R. Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically applied, dermal anti-scarring agents Bioorg Med Chem Lett (2008) 18, 6562-6567. PubMed Europe PubMed DOI I
Lee,S.J. Genetic analysis of the role of proteolysis in the activation of latent myostatin PLoS ONE (2008) 3, e1628-e1628. PubMed Europe PubMed DOI PMC EPMC
Lesiak,M., Augusciak-Duma,A., Szydlo,A., Pruszczynska,K. and Sieron,A.L. Specific inhibition of procollagen C-endopeptidase activity by synthetic peptide with conservative sequence found in chordin Acta Biochim Pol (2008) 55, 297-305. PubMed Europe PubMed I
Mac Sweeney,A., Gil-Parrado,S., Vinzenz,D., Bernardi,A., Hein,A., Bodendorf,U., Erbel,P., Logel,C. and Gerhartz,B. Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases J Mol Biol (2008) 384, 228-239. PubMed Europe PubMed DOI S

2007

Blanc,G., Font,B., Eichenberger,D., Moreau,C., Ricard-Blum,S., Hulmes,D.J. and Moali,C. Insights into how CUB domains can exert specific functions while sharing a common fold: Conserved and specific features of the CUB1 domain contribute to the molecular basis of procollagen C-proteinase enhancer-1 activity J Biol Chem (2007) 282, 16924-16933. PubMed Europe PubMed DOI
Chau,P., Fielding,P.E. and Fielding,C.J. Bone morphogenetic protein-1 (BMP-1) cleaves human proapolipoprotein A1 and regulates its activation for lipid binding Biochemistry (2007) 46, 8445-8450. PubMed Europe PubMed DOI
Fish,P.V., Allan,G.A., Bailey,S., Blagg,J., Butt,R., Collis,M.G., Greiling,D., James,K., Kendall,J., McElroy,A., McCleverty,D., Reed,C., Webster,R. and Whitlock,G.A. Potent and selective nonpeptidic inhibitors of procollagen C-proteinase J Med Chem (2007) 50, 3442-3456. PubMed Europe PubMed DOI I
Hopkins,D.R., Keles,S. and Greenspan,D.S. The bone morphogenetic protein 1/Tolloid-like metalloproteinases Matrix Biol (2007) 26, 508-523. PubMed Europe PubMed DOI PMC EPMC V
Wermter,C., Howel,M., Hintze,V., Bombosch,B., Aufenvenne,K., Yiallouros,I. and Stocker,W. The protease domain of procollagen C-proteinase (BMP1) lacks substrate selectivity, which is conferred by non-proteolytic domains Biol Chem (2007) 388, 513-521. PubMed Europe PubMed DOI

2006

Allan,G.A., Gedge,J.I., Nedderman,A.N., Roffey,S.J., Small,H.F. and Webster,R. Pharmacokinetics and metabolism of UK-383,367 in rats and dogs: a rationale for long-lived plasma radioactivity Xenobiotica (2006) 36, 399-418. PubMed Europe PubMed DOI I
[YEAR:28-2-2006]Ge,G., Zhang,Y., Steiglitz,B.M. and Greenspan,D.S. Mammalian tolloid-like 1 binds procollagen C-proteinase enhancer protein 1 and differs from bone morphogenetic protein 1 in the functional roles of homologous protein domains J Biol Chem (28-2-2006) 281, 10786-10798. PubMed Europe PubMed DOI
Ge,G. and Greenspan,D.S. Developmental roles of the BMP1/TLD metalloproteinases Birth Defects Res C Embryo Today (2006) 78, 47-68. PubMed Europe PubMed DOI V
Ge,G. and Greenspan,D.S. BMP1 controls TGFbeta1 activation via cleavage of latent TGFbeta-binding protein J Cell Biol (2006) 175, 111-120. PubMed Europe PubMed DOI PMC EPMC
[YEAR:30-5-2006]Hintze,V., Howel,M., Wermter,C., Grosse Berkhoff,E., Becker-Pauly,C., Beermann,B., Yiallouros,I. and Stocker,W. The interaction of recombinant subdomains of the procollagen C-proteinase with procollagen I provides a quantitative explanation for functional differences between the two splice variants, mammalian tolloid and bone morphogenetic protein 1 Biochemistry (30-5-2006) 45, 6741-6748. PubMed Europe PubMed DOI R
Reid,R.R., Mogford,J.E., Butt,R., deGiorgio-Miller,A. and Mustoe,T.A. Inhibition of procollagen C-proteinase reduces scar hypertrophy in a rabbit model of cutaneous scarring Wound Repair Regen (2006) 14, 138-141. PubMed Europe PubMed DOI I
Zhang,Y., Ge,G. and Greenspan,D.S. Inhibition of bone morphogenetic protein 1 by native and altered forms of alpha 2-macroglobulin J Biol Chem (2006) 281, 39096-39104. PubMed Europe PubMed DOI

2005

Ge,G., Hopkins,D.R., Ho,W.B. and Greenspan,D.S. GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cells Mol Cell Biol (2005) 25, 5846-5858. PubMed Europe PubMed DOI PMC EPMC
Gonzalez,E.M., Reed,C.C., Bix,G., Fu,J., Zhang,Y., Gopalakrishnan,B., Greenspan,D.S. and Iozzo,R.V. BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan J Biol Chem (2005) 280, 7080-7087. PubMed Europe PubMed DOI
Moali,C., Font,B., Ruggiero,F., Eichenberger,D., Rousselle,P., Francois,V., Oldberg,A., Bruckner-Tuderman,L. and Hulmes,D.J. Substrate-specific modulation of a multisubstrate proteinase. C-terminal processing of fibrillar procollagens is the only BMP-1-dependent activity to be enhanced by PCPE-1 J Biol Chem (2005) 280, 24188-24194. PubMed Europe PubMed DOI
[YEAR:7-4-2005]Petropoulou,V., Garrigue-Antar,L. and Kadler,K.E. Identification of the minimal domain structure of bone morphogenetic protein-1 (BMP-1) for chordinase activity: chordinase activity is not enhanced by procollagen C-proteinase enhancer-1 (PCPE-1) J Biol Chem (7-4-2005) 280, 22616-22623. PubMed Europe PubMed DOI
[YEAR:14-9-2005]Pischon,N., Babakhanlou-Chase,H., Darbois,L., Ho,W.B., Brenner,M.C., Kessler,E., Palamakumbura,A.H. and Trackman,P.C. A procollagen C-proteinase inhibitor diminishes collagen and lysyl oxidase processing but not collagen cross-linking in osteoblastic cultures J Cell Physiol (14-9-2005) 203, 111-117. PubMed Europe PubMed DOI I

2004

[YEAR:20-9-2004]Garrigue-Antar,L., Francois,V. and Kadler,K.E. Deletion of epidermal growth factor-like domains converts mammalian tolloid into a chordinase and effective procollagen C-proteinase J Biol Chem (20-9-2004) 279, 49835-49841. PubMed Europe PubMed DOI R
[YEAR:1-10-2004]Ge,G., Seo,N.S., Liang,X., Hopkins,D.R., Hook,M. and Greenspan,D.S. Bone morphogenetic protein-1/tolloid-related metalloproteinases process osteoglycin and enhance its ability to regulate collagen fibrillogenesis J Biol Chem (1-10-2004) 279, 41626-41633. PubMed Europe PubMed DOI
Kessler,E. Procollagen C-endopeptidase [ISSN:0-12-079610-4] (2004) 2, 609-617. V
[YEAR:9-1-2004]Steiglitz,B.M., Ayala,M., Narayanan,K., George,A. and Greenspan,D.S. Bone morphogenetic protein-1/Tolloid-like proteinases process dentin matrix protein-1 J Biol Chem (9-1-2004) 279, 980-986. PubMed Europe PubMed DOI

2003

[YEAR:28-2-2003]Bernocco,S., Steiglitz,B.M., Svergun,D.I., Petoukhov,M.V., Ruggiero,F., Ricard-Blum,S., Ebel,C., Geourjon,C., Deleage,G., Font,B., Eichenberger,D., Greenspan,D.S. and Hulmes,D.J. Low resolution structure determination shows procollagen C-proteinase enhancer to be an elongated multidomain glycoprotein J Biol Chem (28-2-2003) 278, 7199-7205. PubMed Europe PubMed DOI
Delaet,N.G., Robinson,L.A., Wilson,D.M., Sullivan,R.W., Bradley,E.K., Dankwardt,S.M., Martin,R.L., Van Wart,H.E. and Walker,K.A. Novel inhibitors of procollagen C-terminal proteinase. Part 1: Diamino acid hydroxamates Bioorg Med Chem Lett (2003) 13, 2101-2104. PubMed Europe PubMed DOI I
[YEAR:16-5-2003]Hartigan,N., Garrigue-Antar,L. and Kadler,K.E. Bone morphogenetic protein-1 (BMP-1). Identification of the minimal domain structure for procollagen C-proteinase activity J Biol Chem (16-5-2003) 278, 18045-18049. PubMed Europe PubMed DOI
[YEAR:16-5-2003]Leighton,M. and Kadler,K.E. Paired basic/furin-like proprotein convertase cleavage of pro-BMP-1 in the trans-Golgi network J Biol Chem (16-5-2003) 278, 18478-18484. PubMed Europe PubMed DOI
[YEAR:11-7-2003]Liepinsh,E., Banyai,L., Pintacuda,G., Trexler,M., Patthy,L. and Otting,G. NMR structure of the netrin-like domain (NTR) of human type I procollagen C-proteinase enhancer defines structural consensus of NTR domains and assesses potential proteinase inhibitory activity and ligand binding J Biol Chem (11-7-2003) 278, 25982-25989. PubMed Europe PubMed DOI
[YEAR:1-12-2003]Medeck,R.J., Sosa,S., Morris,N. and Oxford,J.T. BMP-1-mediated proteolytic processing of alternatively spliced isoforms of collagen type XI Biochem J (1-12-2003) 376, 361-368. PubMed Europe PubMed DOI PMC EPMC
Pappano,W.N., Steiglitz,B.M., Scott,I.C., Keene,D.R. and Greenspan,D.S. Use of Bmp1/Tll1 doubly homozygous null mice and proteomics to identify and validate in vivo substrates of bone morphogenetic protein 1/tolloid-like metalloproteinases Mol Cell Biol (2003) 23, 4428-4438. PubMed Europe PubMed DOI PMC EPMC K
[YEAR:21-7-2003]Robinson,L.A., Wilson,D.M., Delaet,N.G., Bradley,E.K., Dankwardt,S.M., Campbell,J.A., Martin,R.L., Van Wart,H.E., Walker,K.A. and Sullivan,R.W. Novel inhibitors of procollagen C-proteinase. Part 2: glutamic acid hydroxamates Bioorg Med Chem Lett (21-7-2003) 13, 2381-2384. PubMed Europe PubMed DOI I
[YEAR:2-5-2003]Veitch,D.P., Nokelainen,P., McGowan,K.A., Nguyen,T.T., Nguyen,N.E., Stephenson,R., Pappano,W.N., Keene,D.R., Spong,S.M., Greenspan,D.S., Findell,P.R. and Marinkovich,M.P. Mammalian tolloid metalloproteinase, and not matrix metalloprotease 2 or membrane type 1 metalloprotease, processes laminin-5 in keratinocytes and skin J Biol Chem (2-5-2003) 278, 15661-15668. PubMed Europe PubMed DOI
[YEAR:23-12-2003]Wolfman,N.M., McPherron,A.C., Pappano,W.N., Davies,M.V., Song,K., Tomkinson,K.N., Wright,J.F., Zhao,L., Sebald,S.M., Greenspan,D.S. and Lee,S.J. Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases Proc Natl Acad Sci U S A (23-12-2003) 100, 15842-15846. PubMed Europe PubMed DOI PMC EPMC

2002

[YEAR:22-4-2002]Dankwardt,S.M., Abbot,S.C., Broka,C.A., Martin,R.L., Chan,C.S., Springman,E.B., Van Wart,H.E. and Walker,K.A. Amino acid derived sulfonamide hydroxamates as inhibitors of procollagen C-proteinase. Part 2: Solid-Phase optimization of side chains Bioorg Med Chem Lett (22-4-2002) 12, 1233-1235. PubMed Europe PubMed DOI I
Garrigue-Antar,L., Hartigan,N. and Kadler,K.E. Post-translational modification of bone morphogenetic protein-1 is required for secretion and stability of the protein J Biol Chem (2002) 277, 43327-43334. PubMed Europe PubMed DOI
[YEAR:19-7-2002]Rattenholl,A., Pappano,W.N., Koch,M., Keene,D.R., Kadler,K.E., Sasaki,T., Timpl,R., Burgeson,R.E., Greenspan,D.S. and Bruckner-Tuderman,L. Proteinases of the bone morphogenetic protein-1 family convert procollagen VII to mature anchoring fibril collagen J Biol Chem (19-7-2002) 277, 26372-26378. PubMed Europe PubMed DOI
[YEAR:13-9-2002]Ricard-Blum,S., Bernocco,S., Font,B., Moali,C., Eichenberger,D., Farjanel,J., Burchardt,E.R., van der Rest,M., Kessler,E. and Hulmes,D.J. Interaction properties of the procollagen C-proteinase enhancer protein shed light on the mechanism of stimulation of BMP-1 J Biol Chem (13-9-2002) 277, 33864-33869. PubMed Europe PubMed DOI
[YEAR:20-12-2002]Steiglitz,B.M., Keene,D.R. and Greenspan,D.S. PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1 J Biol Chem (20-12-2002) 277, 49820-49830. PubMed Europe PubMed DOI
[YEAR:15-2-2002]Unsold,C., Pappano,W.N., Imamura,Y., Steiglitz,B.M. and Greenspan,D.S. Biosynthetic processing of the pro-alpha 1(V)2pro-alpha 2(V) collagen heterotrimer by bone morphogenetic protein-1 and furin-like proprotein convertases J Biol Chem (15-2-2002) 277, 5596-5602. PubMed Europe PubMed DOI

2001

[YEAR:28-12-2001]Borel,A., Eichenberger,D., Farjanel,J., Kessler,E., Gleyzal,C., Hulmes,D.J., Sommer,P. and Font,B. Lysyl oxidase-like protein from bovine aorta. Isolation and maturation to an active form by bone morphogenetic protein-1 J Biol Chem (28-12-2001) 276, 48944-48949. PubMed Europe PubMed DOI
[YEAR:20-8-2001]Dankwardt,S.M., Martin,R.L., Chan,C.S., Van Wart,H.E., Walker,K.A.M., Delaet,N.G. and Robinson,L.A. Amino acid derived sulfonamide hydroxamates as inhibitors of procollagen C-proteinase: solid-phase synthesis of ornithine analogues Bioorg Med Chem Lett (20-8-2001) 11, 2085-2088. PubMed Europe PubMed DOI I
[YEAR:13-7-2001]Garrigue-Antar,L., Barker,C. and Kadler,K.E. Identification of amino acid residues in bone morphogenetic protein-1 important for procollagen C-proteinase activity J Biol Chem (13-7-2001) 276, 26237-26242. PubMed Europe PubMed DOI
Huggins,L.G. and Lennarz,W.J. Inhibitors of procollagen C-terminal proteinase block gastrulation and spicule elongation in the sea urchin embryo Dev Growth Differ (2001) 43, 415-424. PubMed Europe PubMed DOI I
Kessler,E., Fichard,A., Chanut-Delalande,H., Brusel,M. and Ruggiero,F. Bone morphogenetic protein-1 (BMP-1) mediates C-terminal processing of procollagen V homotrimer J Biol Chem (2001) 276, 27051-27057. PubMed Europe PubMed DOI
Moschcovich,L., Bernocco,S., Font,B., Rivkin,H., Eichenberger,D., Chejanovsky,N., Hulmes,D.J. and Kessler,E. Folding and activity of recombinant human procollagen C-proteinase enhancer Eur J Biochem (2001) 268, 2991-2996. PubMed Europe PubMed DOI
[YEAR:22-3-2001]Ross,J.J., Shimmi,O., Vilmos,P., Petryk,A., Kim,H., Gaudenz,K., Hermanson,S., Ekker,S.C., O'Connor,M.B. and Marsh,J.L. Twisted gastrulation is a conserved extracellular BMP antagonist Nature (22-3-2001) 410, 479-483. PubMed Europe PubMed DOI
Steiglitz,B.M. and Greenspan,D.S. Assignment of the mouse Pcolce2 gene, which encodes procollagen C-proteinase enhancer protein 2, to chromosome 9 and localization of PCOLCE2 to human chromosome 3q23 Cytogenet Cell Genet (2001) 95, 244-245. PubMed Europe PubMed
[YEAR:22-6-2001]Uzel,M.I., Scott,I.C., Babakhanlou-Chase,H., Palamakumbura,A.H., Pappano,W.N., Hong,H.H., Greenspan,D.S. and Trackman,P.C. Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures J Biol Chem (22-6-2001) 276, 22537-22543. PubMed Europe PubMed DOI

2000

[YEAR:28-7-2000]Amano,S., Scott,I.C., Takahara,K., Koch,M., Champliaud,M.F., Gerecke,D.R., Keene,D.R., Hudson,D.L., Nishiyama,T., Lee,S., Greenspan,D.S. and Burgeson,R.E. Bone morphogenetic protein 1 is an extracellular processing enzyme of the laminin 5 gamma 2 chain J Biol Chem (28-7-2000) 275, 22728-22735. PubMed Europe PubMed DOI
Dankwardt,S.M., Billedeau,R.J., Lawley,L.K., Abbot,S.C., Martin,R.L., Chan,C.S., Van Wart,H.E. and Walker,K.A. Solid-phase synthesis of di- and tripeptidic hydroxamic acids as inhibitors of procollagen C-proteinase Bioorg Med Chem Lett (2000) 10, 2513-2516. PubMed Europe PubMed I
[YEAR:21-4-2000]Kanaki,T., Morisaki,N., Bujo,H., Takahashi,K., Ishii,I. and Saito,Y. The regulatory expression of procollagen COOH-terminal proteinase enhancer in the proliferation of vascular smooth muscle cells Biochem Biophys Res Commun (21-4-2000) 270, 1049-1054. PubMed Europe PubMed DOI
[YEAR:1-3-2000]Marti,E. Expression of chick BMP-1/Tolloid during patterning of the neural tube and somites Mech Dev (1-3-2000) 91, 415-419. PubMed Europe PubMed DOI
Ovens,A., Joule,J.A. and Kadler,K.E. Design and synthesis of acidic dipeptide hydroxamate inhibitors of procollagen C-proteinase J Pept Sci (2000) 6, 489-495. PubMed Europe PubMed DOI I
[YEAR:2-5-2000]Reynolds,S.D., Zhang,D.H., Puzas,J.E., O'Keefe,R.J., Rosier,R.N. and Reynolds,P.R. Cloning of the chick BMP1/Tolloid cDNA and expression in skeletal tissues Gene (2-5-2000) 248, 233-243. PubMed Europe PubMed DOI
[YEAR:29-9-2000]Scott,I.C., Imamura,Y., Pappano,W.N., Troedel,J.M., Recklies,A.D., Roughley,P.J. and Greenspan,D.S. Bone morphogenetic protein-1 processes probiglycan J Biol Chem (29-9-2000) 275, 30504-30511. PubMed Europe PubMed DOI
[YEAR:28-3-2000]Sieron,A.L., Tretiakova,A., Jameson,B.A., Segall,M.L., Lund-Katz,S., Khan,M.T., Li,S. and Stocker,W. Structure and function of procollagen C-proteinase (mTolloid) domains determined by protease digestion, circular dichroism, binding to procollagen type I, and computer modeling Biochemistry (28-3-2000) 39, 3231-3239. PubMed Europe PubMed DOI

1999

Banyai,L. and Patthy,L. The NTR module: domains of netrins, secreted frizzled related proteins, and type I procollagen C-proteinase enhancer protein are homologous with tissue inhibitors of metalloproteases Protein Sci (1999) 8, 1636-1642. PubMed Europe PubMed DOI PMC EPMC
Dale,L. and Wardle,F.C. A gradient of BMP activity specifies dorsal-ventral fates in early Xenopus embryos Semin Cell Dev Biol (1999) 10, 319-326. PubMed Europe PubMed DOI
[YEAR:15-9-1999]Scott,I.C., Blitz,I.L., Pappano,W.N., Imamura,Y., Clark,T.G., Steiglitz,B.M., Thomas,C.L., Maas,S.A., Takahara,K., Cho,K.W. and Greenspan,D.S. Mammalian BMP-1/tolloid-related metalloproteinases, including novel family member mammalian tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis Dev Biol (15-9-1999) 213, 283-300. PubMed Europe PubMed DOI
[YEAR:15-1-1999]Scott,I.C., Clark,T.G., Takahara,K., Hoffman,G.G. and Greenspan,D.S. Structural organization and expression patterns of the human and mouse genes for the type I procollagen COOH-terminal proteinase enhancer protein Genomics (15-1-1999) 55, 229-234. PubMed Europe PubMed DOI
Wardle,F.C., Welch,J.V. and Dale,L. Bone morphogenetic protein 1 regulates dorsal-ventral patterning in early Xenopus embryos by degrading chordin, a BMP4 antagonist Mech Dev (1999) 86, 75-85. PubMed Europe PubMed DOI

1998

Cho,K.W. and Blitz,I.L. BMPs, Smads and metalloproteases: extracellular and intracellular modes of negative regulation Curr Opin Genet Dev (1998) 8, 443-449. PubMed Europe PubMed DOI
[YEAR:15-3-1998]Goodman,S.A., Albano,R., Wardle,F.C., Matthews,G., Tannahill,D. and Dale,L. BMP1-related metalloproteinases promote the development of ventral mesoderm in early Xenopus embryos Dev Biol (15-3-1998) 195, 144-157. PubMed Europe PubMed DOI
[YEAR:16-10-1998]Imamura,Y., Steiglitz,B.M. and Greenspan,D.S. Bone morphogenetic protein-1 processes the NH2-terminal propeptide, and a furin-like proprotein convertase processes the COOH-terminal propeptide of pro-alpha1(V) collagen J Biol Chem (16-10-1998) 273, 27511-27517. PubMed Europe PubMed DOI
Janitz,M., Heiser,V., Bottcher,U., Landt,O. and Lauster,R. Three alternatively spliced variants of the gene coding for the human bone morphogenetic protein-1 J Mol Med (1998) 76, 141-146. PubMed Europe PubMed DOI
[YEAR:26-3-1998]Lemaire,P. and Yasuo,H. Developmental signalling: a careful balancing act Curr Biol (26-3-1998) 8, R228-R231. PubMed Europe PubMed
Prockop,D.J., Sieron,A.L. and Li,S.W. Procollagen N-proteinase and procollagen C-proteinase. Two unusual metalloproteinases that are essential for procollagen processing probably have important roles in development and cell signaling Matrix Biol (1998) 16, 399-408. PubMed Europe PubMed DOI

1997

Hulmes,D.J., Mould,A.P. and Kessler,E. The CUB domains of procollagen C-proteinase enhancer control collagen assembly solely by their effect on procollagen C-proteinase/bone morphogenetic protein-1 Matrix Biol (1997) 16, 41-45. PubMed Europe PubMed DOI
[YEAR:25-7-1997]Lee,S., Solow-Cordero,D.E., Kessler,E., Takahara,K. and Greenspan,D.S. Transforming growth factor-beta regulation of bone morphogenetic protein-1/procollagen C-proteinase and related proteins in fibrogenic cells and keratinocytes J Biol Chem (25-7-1997) 272, 19059-19066. PubMed Europe PubMed DOI
Martin-Burriel,I., Goldammer,T., Elduque,C., Lundin,M., Barendse,W., Zaragoza,P. and Olsaker,I. Physical and linkage mapping of the bovine bone morphogenetic protein 1 on the evolutionary break region of BTA 8 Cytogenet Cell Genet (1997) 79, 179-183. PubMed Europe PubMed

1996

Hofbauer,L.C. and Heufelder,A.E. Updating the metalloprotease nomenclature: bone morphogenetic protein 1 identified as procollagen C proteinase Eur J Endocrinol (1996) 135, 35-36. PubMed Europe PubMed
Kessler,E., Takahara,K., Biniaminov,L., Brusel,M. and Greenspan,D.S. Bone morphogenetic protein-1: the type I procollagen C-proteinase Science (1996) 271, 360-362. PubMed Europe PubMed
Li,S.W., Sieron,A.L., Fertala,A., Hojima,Y., Arnold,W.V. and Prockop,D.J. The C-proteinase that processes procollagens to fibrillar collagens is identical to the protein previously identified as bone morphogenic protein-1 Proc Natl Acad Sci U S A (1996) 93, 5127-5130. PubMed Europe PubMed DOI PMC EPMC
[YEAR:22-3-1996]Panchenko,M.V., Stetler-Stevenson,W.G., Trubetskoy,O.V., Gacheru,S.N. and Kagan,H.M. Metalloproteinase activity secreted by fibrogenic cells in the processing of prolysyl oxidase. Potential role of procollagen C-proteinase J Biol Chem (22-3-1996) 271, 7113-7119. PubMed Europe PubMed P
Reddi,A.H. BMP-1: resurrection as procollagen C-proteinase Science (1996) 271, 463-463. PubMed Europe PubMed DOI
Sarras,M.P., Jr. BMP-1 and the astacin family of metalloproteinases: a potential link between the extracellular matrix, growth factors and pattern formation Bioessays (1996) 18, 439-442. PubMed Europe PubMed DOI
Suzuki,N., Labosky,P.A., Furuta,Y., Hargett,L., Dunn,R., Fogo,A.B., Takahara,K., Peters,D.M., Greenspan,D.S. and Hogan,B.L. Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid Development (1996) 122, 3587-3595. PubMed Europe PubMed
Takahara,K., Osborne,L., Elliott,R.W., Tsui,L.C., Scherer,S.W. and Greenspan,D.S. Fine mapping of the human and mouse genes for the type I procollagen COOH-terminal proteinase enhancer protein Genomics (1996) 31, 253-256. PubMed Europe PubMed DOI

1995

Kadler,K.E. and Watson,R.B. Procollagen C-peptidase: procollagen C-proteinase Methods Enzymol (1995) 248, 771-781. PubMed Europe PubMed DOI V
Takahara,K., Lee,S., Wood,S. and Greenspan,D.S. Structural organization and genetic localization of the human bone morphogenetic protein 1/mammalian tolloid gene Genomics (1995) 29, 9-15. PubMed Europe PubMed DOI

1994

Fukagawa,M., Suzuki,N., Hogan,B.L. and Jones,C.M. Embryonic expression of mouse bone morphogenetic protein-1 (BMP-1), which is related to the Drosophila dorsoventral gene tolloid and encodes a putative astacin metalloendopeptidase Dev Biol (1994) 163, 175-183. PubMed Europe PubMed DOI
Hojima,Y., Behta,B., Romanic,A.M. and Prockop,D.J. Cadmium ions inhibit procollagen C-proteinase and cupric ions inhibit procollagen N-proteinase Matrix Biol (1994) 14, 113-120. PubMed Europe PubMed
Hwang,S.P., Partin,J.S. and Lennarz,W.J. Characterization of a homolog of human bone morphogenetic protein 1 in the embryo of the sea urchin, Strongylocentrotus purpuratus Development (1994) 120, 559-568. PubMed Europe PubMed
Takahara,K., Lyons,G.E. and Greenspan,D.S. Bone morphogenetic protein-1 and a mammalian tolloid homologue (mtld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues J Biol Chem (1994) 269, 32572-32578. PubMed Europe PubMed R
Takahara,K., Kessler,E., Biniaminov,L., Brusel,M., Eddy,R.L., Jani-Sait,S., Shows,T.B. and Greenspan,D.S. Type I procollagen COOH-terminal proteinase enhancer protein: Identification, primary structure, and chromosomal localization of the cognate human gene (PCOLCE) J Biol Chem (1994) 269, 26280-26285. PubMed Europe PubMed

1993

Maeno,M., Xue,Y., Wood,T.I., Ong,R.C. and Kung,H.F. Cloning and expression of cDNA encoding Xenopus laevis bone morphogenetic protein-1 during early embryonic development Gene (1993) 134, 257-261. PubMed Europe PubMed DOI
Yoshiura,K., Tamura,T., Hong,H.S., Ohta,T., Soejima,H., Kishino,T., Jinno,Y. and Niikawa,N. Mapping of the bone morphogenetic protein 1 gene (BMP1) to 8p21: removal of BMP1 from candidacy for the bone disorder in Langer-Giedion syndrome Cytogenet Cell Genet (1993) 64, 208-209. PubMed Europe PubMed

1992

Reynolds,S.D., Angerer,L.M., Palis,J., Nasir,A. and Angerer,R.C. Early mRNAs, spatially restricted along the animal-vegetal axis of sea urchin embryos, include one encoding a protein related to tolloid and BMP-1 Development (1992) 114, 769-786. PubMed Europe PubMed

1991

Bork,P. Complement components C1r/C1s, bone morphogenic protein 1 and Xenopus laevis developmentally regulated protein UVS.2 share common repeats FEBS Lett (1991) 282, 9-12. PubMed Europe PubMed DOI

1990

[YEAR:15-12-1990]Lee,S.T., Kessler,E. and Greenspan,D.S. Analysis of site-directed mutations in human pro-alpha 2(I) collagen which block cleavage by the C-proteinase J Biol Chem (15-12-1990) 265, 21992-21996. PubMed Europe PubMed
Rawlings,N.D. and Barrett,A.J. Bone morphogenetic protein 1 is homologous in part with calcium-dependent serine proteinase Biochem J (1990) 266, 622-624. PubMed Europe PubMed PMC EPMC

1989

Kessler,E. and Adar,R. Type I procollagen C-proteinase from mouse fibroblasts. Purification and demonstration of a 55-kDa enhancer glycoprotein Eur J Biochem (1989) 186, 115-121. PubMed Europe PubMed DOI

1986

Adar,R., Kessler,E. and Goldberg,B. Evidence for a protein that enhances the activity of type I procollagen C-proteinase Coll Relat Res (1986) 6, 267-277. PubMed Europe PubMed
Kessler,E., Adar,R., Goldberg,B. and Niece,R. Partial purification and characterization of a procollagen C-proteinase from the culture medium of mouse fibroblasts Coll Relat Res (1986) 6, 249-266. PubMed Europe PubMed

1985

Hojima,Y., van der Rest,M. and Prockop,D.J. Type I procollagen carboxyl-terminal proteinase from chick embryo tendons. Purification and characterization J Biol Chem (1985) 260, 15996-16003. PubMed Europe PubMed

1982

[YEAR:16-2-1982]Njieha,F.K., Morikawa,T., Tuderman,L. and Prockop,D.J. Partial purification of a procollagen C-proteinase. Inhibition by synthetic peptides and sequential cleavage of type I procollagen Biochemistry (16-2-1982) 21, 757-764. PubMed Europe PubMed

1979

Leung,M.K., Fessler,L.I., Greenberg,D.B. and Fessler,J.H. Separate amino and carboxyl procollagen peptidases in chick embryo tendon J Biol Chem (1979) 254, 224-232. PubMed Europe PubMed

1978

Kessler,E. and Goldberg,B. A method for assaying the activity of the endopeptidase which excises the nonhelical carboxyterminal extensions from type I procollagen Anal Biochem (1978) 86, 463-469. PubMed Europe PubMed