Literature for peptidase M10.023: membrane-type matrix metallopeptidase-5

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Pharma

(Topics flags: M Mutation, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2021
  1. Arnst,N., Belio-Mairal,P., Garcia-Gonzalez,L., Arnaud,L., Greetham,L., Nivet,E., Rivera,S. and Dityatev,A. \<br\>Deficiency in MT5-MMP Supports Branching of Human iPSCs-Derived Neurons and Reduces Expression of GLAST/S100 in iPSCs-Derived Astrocytes\<br\>Cells (2021) 10, 1705. PubMed  Europe PubMed DOI  PMC  EPMC
  2. Garcia-Gonzalez,L., Paumier,J.M., Louis,L., Pilat,D., Bernard,A., Stephan,D., Jullien,N., Checler,F., Nivet,E., Khrestchatisky,M., Baranger,K. and Rivera,S. \<br\>MT5-MMP controls APP and beta-CTF/C99 metabolism through proteolytic-dependent and -independent mechanisms relevant for Alzheimer's disease\<br\>FASEB J (2021) 35, e21727. PubMed  Europe PubMed DOI
  3. 2016
  4. Baranger,K., Marchalant,Y., Bonnet,A.E., Crouzin,N., Carrete,A., Paumier,J.M., Py,N.A., Bernard,A., Bauer,C., Charrat,E., Moschke,K., Seiki,M., Vignes,M., Lichtenthaler,S.F., Checler,F., Khrestchatisky,M. and Rivera,S. \<br\>MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease\<br\>Cell Mol Life Sci (2016) 73, 217-236. PubMed  Europe PubMed DOI
  5. Baranger,K., Khrestchatisky,M. and Rivera,S. \<br\>MT5-MMP, just a new APP processing proteinase in Alzheimer's disease?\<br\>J Neuroinflammation (2016) 13, 167. PubMed  Europe PubMed DOI  PMC  EPMC
  6. Baranger,K., Bonnet,A.E., Girard,S.D., Paumier,J.M., Garcia-Gonzalez,L., Elmanaa,W., Bernard,A., Charrat,E., Stephan,D., Bauer,C., Moschke,K., Lichtenthaler,S.F., Roman,F.S., Checler,F., Khrestchatisky,M. and Rivera,S. \<br\>MT5-MMP promotes Alzheimer's pathogenesis in the frontal cortex of 5xFAD mice and APP trafficking in vitro\<br\>Front Mol Neurosci (2016) 9, 163. PubMed  Europe PubMed DOI  PMC  EPMC
  7. 2015
  8. Willem,M., Tahirovic,S., Busche,M.A., Ovsepian,S.V., Chafai,M., Kootar,S., Hornburg,D., Evans,L.D., Moore,S., Daria,A., Hampel,H., Muller,V., Giudici,C., Nuscher,B., Wenninger-Weinzierl,A., Kremmer,E., Heneka,M.T., Thal,D.R., Giedraitis,V., Lannfelt,L., Muller,U., Livesey,F.J., Meissner,F., Herms,J., Konnerth,A., Marie,H. and Haass,C. \<br\>Eta-secretase processing of APP inhibits neuronal activity in the hippocampus\<br\>Nature (2015) 526, 443-447. PubMed  Europe PubMed DOI
  9. 2014
  10. Porlan,E., Marti-Prado,B., Morante-Redolat,J.M., Consiglio,A., Delgado,A.C., Kypta,R., Lopez-Otin,C., Kirstein,M. and Farinas,I. \<br\>MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin\<br\>Nat Cell Biol (2014) 16, 629-638. PubMed  Europe PubMed DOI
  11. 2013
  12. Takahashi,T., Fujimori,C., Hagiwara,A. and Ogiwara,K. \<br\>Recent advances in the understanding of teleost medaka ovulation: the roles of proteases and prostaglandins\<br\>Zoolog Sci (2013) 30, 239-247. PubMed  Europe PubMed DOI
  13. 2012
  14. Pei,D. \<br\>Membrane-type matrix metalloproteinase 5\<br\>[ISSN:978-0-12-407744-7] (2012) 3, 826-828. DOI
  15. 2007
  16. Gaetje,R., Holtrich,U., Engels,K., Kourtis,K., Cikrit,E., Kissler,S., Rody,A., Karn,T. and Kaufmann,M. \<br\>Expression of membrane-type 5 matrix metalloproteinase in human endometrium and endometriosis\<br\>Gynecol Endocrinol (2007) 23, 567-573. PubMed  Europe PubMed DOI
  17. Ross,H.H. and Fillmore,H.L. \<br\>Identification of a novel human MT5-MMP transcript variant in multipotent NT2 cells\<br\>FEBS Lett (2007) 581, 5923-5928. PubMed  Europe PubMed DOI  M
  18. 2004
  19. [YEAR:16-1-2004]Komori,K., Nonaka,T., Okada,A., Kinoh,H., Hayashita-Kinoh,H., Yoshida,N., Yana,I. and Seiki,M. \<br\>Absence of mechanical allodynia and Abeta-fiber sprouting after sciatic nerve injury in mice lacking membrane-type 5 matrix metalloproteinase\<br\>FEBS Lett (16-1-2004) 557, 125-128. PubMed  Europe PubMed DOI
  20. Pei,D. \<br\>Membrane-type matrix metalloproteinase 5\<br\>[ISSN:0-12-079610-4] (2004) 2, 555-557.  V
  21. 2001
  22. Dong,Z., Katar,M., Alousi,S. and Berk,R.S. \<br\>Expression of membrane-type matrix metalloproteinases 4, 5, and 6 in mouse corneas infected with P. aeruginosa\<br\>Invest Ophthalmol Vis Sci (2001) 42, 3223-3227. PubMed  Europe PubMed
  23. Hayashita-Kinoh,H., Kinoh,H., Okada,A., Komori,K., Itoh,Y., Chiba,T., Kajita,M., Yana,I. and Seiki,M. \<br\>Membrane-type 5 matrix metalloproteinase is expressed in differentiated neurons and regulates axonal growth\<br\>Cell Growth Differ (2001) 12, 573-580. PubMed  Europe PubMed
  24. [YEAR:19-3-2001]Kimura,A., Shinohara,M., Ohkura,R. and Takahashi,T. \<br\>Expression and localization of transcripts of MT5-MMP and its related MMP in the ovary of the medaka fish Oryzias latipes\<br\>Biochim Biophys Acta (19-3-2001) 1518, 115-123. PubMed  Europe PubMed DOI
  25. Romanic,A.M., Burns-Kurtis,C.L., Ao,Z., Arleth,A.J. and Ohlstein,E.H. \<br\>Upregulated expression of human membrane type-5 matrix metalloproteinase in kidneys from diabetic patients\<br\>Am J Physiol Renal Physiol (2001) 281, F309-F317. PubMed  Europe PubMed
  26. Sekine-Aizawa,Y., Hama,E., Watanabe,K., Tsubuki,S., Kanai-Azuma,M., Kanai,Y., Arai,H., Aizawa,H., Iwata,N. and Saido,T.C. \<br\>Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain-specific MMP highly expressed in cerebellum\<br\>Eur J Neurosci (2001) 13, 935-948. PubMed  Europe PubMed DOI
  27. [YEAR:21-9-2001]Wang,X. and Pei,D. \<br\>Shedding of membrane type matrix metalloproteinase 5 by a furin-type convertase: a potential mechanism for down-regulation\<br\>J Biol Chem (21-9-2001) 276, 35953-35960. PubMed  Europe PubMed DOI  I
  28. 2000
  29. [YEAR:31-3-2000]Jaworski,D.M. \<br\>Developmental regulation of membrane type-5 matrix metalloproteinase (MT5-MMP) expression in the rat nervous system\<br\>Brain Res (31-3-2000) 860, 174-177. PubMed  Europe PubMed DOI
  30. 1999
  31. Kinoh,H., Hayashita,H., Kajita,M., Okada,A. and Seiki,M. \<br\>Assignment of the genes for membrane-type-4 matrix metalloproteinase (Mmp17, MMP17) to mouse chromosome 5, human chromosome band 12q24.3 and membrane-type-5 matrix metalloproteinase (Mmp24, MMP24) to mouse chromosome 2 and human chromosome band 20q11.2 - >q12, respectively, by radiation hybrid and in situ hybridization\<br\>Cytogenet Cell Genet (1999) 87, 97-98. PubMed  Europe PubMed
  32. [YEAR:1-6-1999]Llano,E., Pendas,A.M., Freije,J.P., Nakano,A., Knauper,V., Murphy,G. and Lopez-Otin,C. \<br\>Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase A overexpressed in brain tumors\<br\>Cancer Res (1-6-1999) 59, 2570-2576. PubMed  Europe PubMed
  33. [YEAR:26-3-1999]Pei,D. \<br\>Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP\<br\>J Biol Chem (26-3-1999) 274, 8925-8932. PubMed  Europe PubMed DOI
  34. [YEAR:3-12-1999]Wang,X., Yi,J., Lei,J. and Pei,D. \<br\>Expression, purification and characterization of recombinant mouse MT5-MMP protein products\<br\>FEBS Lett (3-12-1999) 462, 261-266. PubMed  Europe PubMed DOI  E