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Literature for peptidase M10.002: matrix metallopeptidase-8

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, P Specificity, K Knockout, E Expression, V Review, M Mutation, I Inhibitor, L Localization. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Deng,X., You,Y., Lv,S. and Liu,Y.
    MMP8-mediated vascular remodeling in pulmonary hypertension
    Biochim Biophys Acta Mol Basis Dis1871, 167582-167582. PubMed  Europe PubMed DOI
  2. Zhang,D., Xu,C., Liang,M., Shao,W., Wang,P., Yang,Y. and Guo,K.
    Diagnostic Accuracy of Matrix Metalloproteinase-8 for Detecting Periodontal Disease: A Meta-Analysis
    Oral Dis PubMed  Europe PubMed DOI
    3. 2024
  3. Cathomas,F., Lin,H.Y., Chan,K.L., Li,L., Parise,L.F., Alvarez,J., Durand-de Cuttoli,R., Aubry,A.V., Muhareb,S., Desland,F., Shimo,Y., Ramakrishnan,A., Estill,M., Ferrer-Perez,C., Parise,E.M., Wilk,C.M., Kaster,M.P., Wang,J., Sowa,A., Janssen,W.G., Costi,S., Rahman,A., Fernandez,N., Campbell,M., Swirski,F.K., Nestler,E.J., Shen,L., Merad,M., Murrough,J.W. and Russo,S.J.
    Circulating myeloid-derived MMP8 in stress susceptibility and depression
    Nature626, 1108-1115. PubMed  Europe PubMed DOI
  4. Dibdiakova,K., Majercikova,Z., Galanda,T., Richterova,R., Kolarovszki,B., Racay,P. and Hatok,J.
    Relationship between the Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Patients with Brain Tumors
    Int J Mol Sci25, PubMed  Europe PubMed DOI
  5. Ranta,J., Havulinna,A.S., Tervahartiala,T., Niemi,K., Aarabi,G., Vihervaara,T., Salomaa,V., Sorsa,T., Pussinen,P.J. and Salminen,A.
    Serum MMP-8 and TIMP-1 concentrations in a population-based cohort: effects of age, gender, and health status
    Front Dent Med5, 1315596-1315596. PubMed  Europe PubMed DOI
  6. Yates,D.
    MMP8 and stress susceptibility
    Nat Rev Neurosci25, 209-209. PubMed  Europe PubMed DOI
    7. 2023
  7. Atanasova,T., Stankova,T., Bivolarska,A. and Vlaykova,T.
    Matrix Metalloproteinases in Oral Health-Special Attention on MMP-8
    Biomedicines11, PubMed  Europe PubMed DOI
    8. 2022
  8. Fang,X., Duan,S.F., Hu,Z.Y., Wang,J.J., Qiu,L., Wang,F. and Chen,X.L.
    Inhibition of Matrix Metalloproteinase-8 Protects Against Sepsis Serum Mediated Leukocyte Adhesion
    Front Med (Lausanne)9, 814890-814890. PubMed  Europe PubMed DOI
  9. Gu,H., Peng,J., Wang,M., Guo,Z., Huang,H. and Yan,L.
    MicroRNA-320-3p promotes the progression of acute pancreatitis by blocking DNMT3a-mediated MMP8 methylation in a targeted manner
    Mol Immunol151, 84-94. PubMed  Europe PubMed DOI
  10. Lahteenmaki,H., Tervahartiala,T., Raisanen,I.T., Parnanen,P., Mauramo,M., Gupta,S., Sampson,V., Rathnayake,N., Heikkinen,A.M., Alassiri,S., Gieselmann,D.R., Frankenberger,R. and Sorsa,T.
    Active MMP-8 point-of-care (PoC)/chairside enzyme-test as an adjunctive tool for early and real-time diagnosis of peri-implantitis
    Clin Exp Dent Res8, 485-496. PubMed  Europe PubMed DOI  L
  11. Lee,M.R., Chen,Y.L., Wu,C.W., Chen,L.C., Chang,L.Y., Chen,J.Y., Huang,Y.T., Wang,J.Y., Shih,J.Y. and Yu,C.J.
    Toll-like receptor and matrix metalloproteinase single-nucleotide polymorphisms, haplotypes, and polygenic risk score differentiated between tuberculosis disease and infection
    Int J Infect Dis125, 61-66. PubMed  Europe PubMed DOI  M
  12. Samulenas,G., Insodaite,R., Kunceviciene,E., Poceviciute,R., Masionyte,L., Zitkeviciute,U., Pilipaityte,L. and Smalinskiene,A.
    The Role of Functional Polymorphisms in the Extracellular Matrix Modulation-Related Genes on Dupuytren's Contracture
    Genes (Basel)13, PubMed  Europe PubMed DOI
  13. Umeizudike,K.A., Lahteenmaki,H., Raisanen,I.T., Taylor,J.J., Preshaw,P.M., Bissett,S.M., Tervahartiala,T., Nwhator,O., Parnanen,P. and Sorsa,T.
    Ability of matrix metalloproteinase-8 biosensor, IFMA, and ELISA immunoassays to differentiate between periodontal health, gingivitis, and periodontitis
    J Periodontal Res57, 558-567. PubMed  Europe PubMed DOI
  14. Zhang,C., Niu,K., Ren,M., Zhou,X., Yang,Z., Yang,M., Wang,X., Luo,J., Shao,Y., Zhang,C., Chen,D., Gao,S., Ge,S., Wu,Q. and Xiao,Q.
    Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model
    Cells11, PubMed  Europe PubMed DOI
    15. 2021
  15. Bassiouni,W., Ali,M.A.M. and Schulz,R.
    Multifunctional intracellular matrix metalloproteinases: implications in disease
    FEBS J288, 7162-7182. PubMed  Europe PubMed DOI  V
  16. Guti,S., Baidya,S.K., Banerjee,S., Adhikari,N. and Jha,T.
    A robust classification-dependent multi-molecular modelling study on some biphenyl sulphonamide based MMP-8 inhibitors
    SAR QSAR Environ Res32, 835-861. PubMed  Europe PubMed DOI  I
  17. Hernandez,M., Baeza,M., Raisanen,I.T., Contreras,J., Tervahartiala,T., Chaparro,A., Sorsa,T. and Hernandez-Rios,P.
    Active MMP-8 Quantitative Test as an Adjunctive Tool for Early Diagnosis of Periodontitis
    Diagnostics (Basel)11, 1503-1503. PubMed  Europe PubMed DOI
  18. Petain,S., Kasnak,G., Firatli,E., Tervahartiala,T., Gursoy,U.K. and Sorsa,T.
    Periodontitis and peri-implantitis tissue levels of Treponema denticola-CTLP and its MMP-8 activating ability
    Acta Histochem123, 151767-151767. PubMed  Europe PubMed DOI
  19. Wang,X., Zhang,D., Fucci,Q.A., Dollery,C.M. and Owen,C.A.
    Surface-bound matrix metalloproteinase-8 on macrophages: Contributions to macrophage pericellular proteolysis and migration through tissue barriers
    Physiol Rep9, e14778-e14778. PubMed  Europe PubMed DOI
    20. 2020
  20. Morla,S. and Desai,U.R.
    Discovery of Sulfated Small Molecule Inhibitors of Matrix Metalloproteinase-8
    Biomolecules10, 1166-1166. PubMed  Europe PubMed DOI  I
  21. Roy,H.S., Dubey,G., Sharma,V.K., Bharatam,P.V. and Ghosh,D.
    Molecular docking and molecular dynamics to identify collagenase inhibitors as lead compounds to address osteoarthritis
    J Biomol Struct Dyn1-13. PubMed  Europe PubMed DOI  I
  22. Wu,W., Peng,S., Shi,Y., Li,L., Song,Z. and Lin,S.
    NPY promotes macrophage migration by upregulating matrix metalloproteinase-8 expression
    J Cell Physiol236, 1903-1912. PubMed  Europe PubMed DOI
    23. 2019
  23. Abu Bakar,A.R., Ripen,A.M., Merican,A.F. and Mohamad,S.B.
    Enzymatic inhibitory activity of Ficus deltoidea leaf extract on matrix metalloproteinase-2, 8 and 9
    Nat Prod Res33, 1765-1768. PubMed  Europe PubMed DOI  I
    24. 2018
  24. Kumar,H., Jo,M.J., Choi,H., Muttigi,M.S., Shon,S., Kim,B.J., Lee,S.H. and Han,I.B.
    Matrix metalloproteinase-8 inhibition prevents disruption of blood-spinal cord barrier and attenuates inflammation in rat model of spinal cord injury
    Mol Neurobiol55, 2577-2590. PubMed  Europe PubMed DOI  I
    25. 2017
  25. Inanc,S., Keles,D. and Oktay,G.
    An improved collagen zymography approach for evaluating the collagenases MMP-1, MMP-8, and MMP-13
    Biotechniques63, 174-180. PubMed  Europe PubMed DOI  L
    26. 2016
  26. Demeestere,D., Dejonckheere,E., Steeland,S., Hulpiau,P., Haustraete,J., Devoogdt,N., Wichert,R., Becker-Pauly,C., Van Wonterghem,E., Dewaele,S., Van Imschoot,G., Aerts,J., Arckens,L., Saeys,Y., Libert,C. and Vandenbroucke,R.E.
    Development and validation of a small single-domain antibody that effectively inhibits matrix metalloproteinase 8
    Mol Ther24, 890-902. PubMed  Europe PubMed DOI
  27. Han,J.E., Lee,E.J., Moon,E., Ryu,J.H., Choi,J.W. and Kim,H.S.
    Matrix metalloproteinase-8 is a novel pathogenetic factor in focal cerebral ischemia
    Mol Neurobiol53, 231-239. PubMed  Europe PubMed DOI  K
  28. Tucker,J.K., McNiff,M.L., Ulapane,S.B., Spencer,P., Laurence,J.S. and Berrie,C.L.
    Mechanistic investigations of matrix metalloproteinase-8 inhibition by metal abstraction peptide
    Biointerphases11, 021006-021006. PubMed  Europe PubMed DOI  I
    29. 2015
  29. Salminen,A., Astrom,P., Metso,J., Soliymani,R., Salo,T., Jauhiainen,M., Pussinen,P.J. and Sorsa,T.
    Matrix metalloproteinase 8 degrades apolipoprotein A-I and reduces its cholesterol efflux capacity
    FASEB J29, 1435-1445. PubMed  Europe PubMed DOI
  30. Wen,G., Zhang,C., Chen,Q., Luong,l.A., Mustafa,A., Ye,S. and Xiao,Q.
    A novel role of matrix metalloproteinase-8 in macrophage differentiation and polarization
    J Biol Chem290, 19158-19172. PubMed  Europe PubMed DOI
    31. 2014
  31. Arnett,E., Vadia,S., Nackerman,C.C., Oghumu,S., Satoskar,A.R., McLeish,K.R., Uriarte,S.M. and Seveau,S.
    The pore-forming toxin listeriolysin O is degraded by neutrophil metalloproteinase-8 and fails to mediate Listeria monocytogenes intracellular survival in neutrophils
    J Immunol192, 234-244. PubMed  Europe PubMed DOI
  32. Ding,D., Lichtenwalter,K., Pi,H., Mobashery,S. and Chang,M.
    Characterization of a selective inhibitor for matrix metalloproteinase-8 (MMP-8)
    MedChemComm5, 1381-1383. DOI  I
  33. Kalva,S., Vinod,D. and Saleena,L.M.
    Combined structure- and ligand-based pharmacophore modeling and molecular dynamics simulation studies to identify selective inhibitors of MMP-8
    J Mol Model20, 2191-2191. PubMed  Europe PubMed DOI  I
  34. Lee,E.J., Han,J.E., Woo,M.S., Shin,J.A., Park,E.M., Kang,J.L., Moon,P.G., Baek,M.C., Son,W.S., Ko,Y.T., Choi,J.W. and Kim,H.S.
    Matrix metalloproteinase-8 plays a pivotal role in neuroinflammation by modulating TNF-alpha activation
    J Immunol193, 2384-2393. PubMed  Europe PubMed DOI
    35. 2013
  35. Chakrabarti,B., Bairagya,H.R., Mishra,D.K., Chatterjee,P.K. and Mukhopadhyay,B.P.
    Insight towards the conserved water mediated recognition of catalytic and structural Zn(+2) ions in human matrix metalloproteinase-8 enzyme: A study by MD-simulation methods
    Bioinformation9, 126-133. PubMed  Europe PubMed DOI
  36. Hugenberg,V., Riemann,B., Hermann,S., Schober,O., Schafers,M., Szardenings,K., Lebedev,A., Gangadharmath,U., Kolb,H., Walsh,J., Zhang,W., Kopka,K. and Wagner,S.
    Inverse 1,2,3-triazole-1-yl-ethyl substituted hydroxamates as highly potent matrix metalloproteinase inhibitors: (Radio)synthesis, in vitro and first in vivo evaluation
    J Med Chem56, 6858-6870. PubMed  Europe PubMed DOI  I
  37. Lu,K.G. and Stultz,C.M.
    Insight into the degradation of type-I collagen fibrils by MMP-8
    J Mol Biol425, 1815-1825. PubMed  Europe PubMed DOI
  38. Mori,M., Massaro,A., Calderone,V., Fragai,M., Luchinat,C. and Mordini,A.
    Discovery of a new class of potent MMP inhibitors by structure-based optimization of the arylsulfonamide scaffold
    ACS Med Chem Lett4, 565-569. PubMed  Europe PubMed DOI  I
    39. 2012
  39. Solan,P.D., Dunsmore,K.E., Denenberg,A.G., Odoms,K., Zingarelli,B. and Wong,H.R.
    A novel role for matrix metalloproteinase-8 in sepsis
    Crit Care Med40, 379-387. PubMed  Europe PubMed DOI  K
  40. Tschesche,H. and Wenzel,H.
    Neutrophil collagenase
    [ISSN:978-0-12-407744-7]3, 725-734. DOI
    41. 2011
  41. Robichaud,T.K., Steffensen,B. and Fields,G.B.
    Exosite interactions impact matrix metalloproteinase collagen specificities
    J Biol Chem286, 37535-37542. PubMed  Europe PubMed DOI  P
    42. 2010
  42. Devel,L., Czarny,B., Beau,F., Georgiadis,D., Stura,E. and Dive,V.
    Third generation of matrix metalloprotease inhibitors: gain in selectivity by targeting the depth of the S1' cavity
    Biochimie92, 1501-1508. PubMed  Europe PubMed DOI  I
  43. Garcia,S., Forteza,J., Lopez-Otin,C., Gomez-Reino,J.J., Gonzalez,A. and Conde,C.
    Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model
    Arthritis Res Ther12, R224-R224. PubMed  Europe PubMed DOI  K
    44. 2009
  44. Lopez-Otin,C., Palavalli,L.H. and Samuels,Y.
    Protective roles of matrix metalloproteinases: from mouse models to human cancer
    Cell Cycle8, 3657-3662. PubMed  Europe PubMed DOI
  45. Palavalli,L.H., Prickett,T.D., Wunderlich,J.R., Wei,X., Burrell,A.S., Porter-Gill,P., Davis,S., Wang,C., Cronin,J.C., Agrawal,N.S., Lin,J.C., Westbroek,W., Hoogstraten-Miller,S., Molinolo,A.A., Fetsch,P., Filie,A.C., O'Connell,M.P., Banister,C.E., Howard,J.D., Buckhaults,P., Weeraratna,A.T., Brody,L.C., Rosenberg,S.A. and Samuels,Y.
    Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma
    Nat Genet41, 518-520. PubMed  Europe PubMed DOI  M
  46. Pochetti,G., Montanari,R., Gege,C., Chevrier,C., Taveras,A.G. and Mazza,F.
    Extra binding region induced by non-zinc chelating inhibitors into the S1' subsite of matrix metalloproteinase 8 (MMP-8)
    J Med Chem52, 1040-1049. PubMed  Europe PubMed DOI  S  I
    47. 2007
  47. [YEAR:25-1-2007]Aschi,M., Besker,N., Re,N., Pochetti,G., Coletti,C., Gallina,C. and Mazza,F.
    Stereoselectivity by enantiomeric inhibitors of matrix metalloproteinase-8: new insights from molecular dynamics simulations
    J Med Chem50, 211-218. PubMed  Europe PubMed DOI  I
  48. Cheng,J., Sauthoff,H., Huang,Y., Kutler,D.I., Bajwa,S., Rom,W.N. and Hay,J.G.
    Human matrix metalloproteinase-8 gene delivery increases the oncolytic activity of a replicating adenovirus
    Mol Ther15, 1982-1990. PubMed  Europe PubMed DOI
  49. Gioia,M., Monaco,S., Fasciglione,G.F., Coletti,A., Modesti,A., Marini,S. and Coletta,M.
    Characterization of the mechanisms by which gelatinase A, neutrophil collagenase, and membrane-type metalloproteinase MMP-14 recognize collagen I and enzymatically process the two alpha-chains
    J Mol Biol368, 1101-1113. PubMed  Europe PubMed DOI
  50. Sulkala,M., Tervahartiala,T., Sorsa,T., Larmas,M., Salo,T. and Tjaderhane,L.
    Matrix metalloproteinase-8 (MMP-8) is the major collagenase in human dentin
    Arch Oral Biol52, 121-127. PubMed  Europe PubMed DOI
    51. 2006
  51. Bertini,I., Calderone,V., Fragai,M., Luchinat,C., Maletta,M. and Yeo,K.J.
    Snapshots of the reaction mechanism of matrix metalloproteinases
    Angew Chem Int Ed Engl45, 7952-7955. PubMed  Europe PubMed DOI  S
  52. [YEAR:17-10-2006]Campestre,C., Agamennone,M., Tortorella,P., Preziuso,S., Biasone,A., Gavuzzo,E., Pochetti,G., Mazza,F., Hiller,O., Tschesche,H., Consalvi,V. and Gallina,C.
    N-Hydroxyurea as zinc binding group in matrix metalloproteinase inhibition: mode of binding in a complex with MMP-8
    Bioorg Med Chem Lett16, 20-24. PubMed  Europe PubMed DOI  S  I
  53. [YEAR:9-2-2006]Pochetti,G., Gavuzzo,E., Campestre,C., Agamennone,M., Tortorella,P., Consalvi,V., Gallina,C., Hiller,O., Tschesche,H., Tucker,P.A. and Mazza,F.
    Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates
    J Med Chem49, 923-931. PubMed  Europe PubMed DOI  S  I
  54. [YEAR:1-7-2006]Van Lint,P. and Libert,C.
    Matrix metalloproteinase-8: Cleavage can be decisive
    Cytokine Growth Factor Rev17, 217-223. PubMed  Europe PubMed DOI  V
    55. 2005
  55. Agamennone,M., Campestre,C., Preziuso,S., Consalvi,V., Crucianelli,M., Mazza,F., Politi,V., Ragno,R., Tortorella,P. and Gallina,C.
    Synthesis and evaluation of new tripeptide phosphonate inhibitors of MMP-8 and MMP-2
    Eur J Med Chem40, 271-279. PubMed  Europe PubMed DOI  I
  56. Pelman,G.R., Morrison,C.J. and Overall,C.M.
    Pivotal molecular determinants of peptidic and collagen triple helicase activities reside in the S3' subsite of matrix metalloproteinase 8 (MMP-8): the role of hydrogen bonding potential of ASN188 and TYR189 and the connecting cis bond
    J Biol Chem280, 2370-2377. PubMed  Europe PubMed DOI  S
  57. [YEAR:1-12-2005]Van Lint,P., Wielockx,B., Puimege,L., Noel,A., Lopez-Otin,C. and Libert,C.
    Resistance of collagenase-2 (matrix metalloproteinase-8)-deficient mice to TNF-induced lethal hepatitis
    J Immunol175, 7642-7649. PubMed  Europe PubMed  K
    58. 2004
  58. Rajasekhar,L., Liou,L.B., Chan,C.Y., Tsai,W.P. and Cheng,C.Y.
    Matrix metalloproteinase-8 in sera and from polymorphonuclear leucocytes in rheumatoid arthritis: in vitro characterization and correlation with disease activity
    Clin Exp Rheumatol22, 597-602. PubMed  Europe PubMed
  59. Siller-Lopez,F., Sandoval,A., Salgado,S., Salazar,A., Bueno,M., Garcia,J., Vera,J., Galvez,J., Hernandez,I., Ramos,M., Aguilar-Cordova,E. and Armendariz-Borunda,J.
    Treatment with human metalloproteinase-8 gene delivery ameliorates experimental rat liver cirrhosis
    Gastroenterology126, 1122-1133. PubMed  Europe PubMed DOI
  60. Tschesche,H., Pieper,M. and Wenzel,H.
    Neutrophil collagenase
    [ISSN:0-12-079610-4]2, 480-486.  V
  61. [YEAR:1-11-2004]Wang,H., Parry,S., Macones,G., Sammel,M.D., Ferrand,P.E., Kuivaniemi,H., Tromp,G., Halder,I., Shriver,M.D., Romero,R. and Strauss,J.F., III
    Functionally significant SNP MMP8 promoter haplotypes and preterm premature rupture of membranes (PPROM)
    Hum Mol Genet13, 2659-2669. PubMed  Europe PubMed DOI  M
    62. 2003
  62. Balbin,M., Fueyo,A., Tester,A.M., Pendas,A.M., Pitiot,A.S., Astudillo,A., Overall,C.M., Shapiro,S.D. and Lopez-Otin,C.
    Loss of collagenase-2 confers increased skin tumor susceptibility to male mice
    Nat Genet35, 252-257. PubMed  Europe PubMed DOI  K
  63. Van Den Steen,P.E., Husson,S.J., Proost,P., Van Damme,J. and Opdenakker,G.
    Carboxyterminal cleavage of the chemokines MIG and IP-10 by gelatinase B and neutrophil collagenase
    Biochem Biophys Res Commun310, 889-896. PubMed  Europe PubMed DOI
  64. Van Den Steen,P.E., Wuyts,A., Husson,S.J., Proost,P., Van Damme,J. and Opdenakker,G.
    Gelatinase B/MMP-9 and neutrophil collagenase/MMP-8 process the chemokines human GCP-2/CXCL6, ENA-78/CXCL5 and mouse GCP-2/LIX and modulate their physiological activities
    Eur J Biochem270, 3739-3749. PubMed  Europe PubMed DOI
    65. 2002
  65. Aschi,M., Roccatano,D., Di Nola,A., Gallina,C., Gavuzzo,E., Pochetti,G., Pieper,M., Tschesche,H. and Mazza,F.
    Computational study of the catalytic domain of human neutrophil collagenase. specific role of the S3 and S'3 subsites in the interaction with a phosphonate inhibitor
    J Comput Aided Mol Des16, 213-225. PubMed  Europe PubMed DOI  I
  66. Gioia,M., Fasciglione,G.F., Marini,S., D'Alessio,S., De Sanctis,G., Diekmann,O., Pieper,M., Politi,V., Tschesche,H. and Coletta,M.
    Modulation of the catalytic activity of neutrophil collagenase MMP-8 on bovine collagen I. Role of the activation cleavage and of the hemopexin-like domain
    J Biol Chem277, 23123-23130. PubMed  Europe PubMed DOI
    67. 2001
  67. [YEAR:1-5-2001]Bigg,H.F., Morrison,C.J., Butler,G.S., Bogoyevitch,M.A., Wang,Z.P., Soloway,P.D. and Overall,C.M.
    Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase
    Cancer Res61, 3610-3618. PubMed  Europe PubMed
  68. [YEAR:18-5-2001]Brandstetter,H., Grams,F., Glitz,D., Lang,A., Huber,R., Bode,W., Krell,H.W. and Engh,R.A.
    The 1.8-A crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition
    J Biol Chem276, 17405-17412. PubMed  Europe PubMed DOI  S  I
  69. Stix,B., Kahne,T., Sletten,K., Raynes,J., Roessner,A. and Rocken,C.
    Proteolysis of AA amyloid fibril proteins by matrix metalloproteinases-1, -2, and -3
    Am J Pathol159, 561-570. PubMed  Europe PubMed DOI
  70. [YEAR:2-11-2001]Stratmann,B., Farr,M. and Tschesche,H.
    MMP-TIMP interaction depends on residue 2 in TIMP-4
    FEBS Lett507, 285-287. PubMed  Europe PubMed DOI
  71. [YEAR:11-5-2001]Zhuge,Y. and Xu,J.
    Rac1 mediates type I collagen-dependent MMP-2 activation: role in cell invasion across collagen barrier
    J Biol Chem276, 16248-16256. PubMed  Europe PubMed
    72. 2000
  72. Fasciglione,G.F., Marini,S., D'Alessio,S., Politi,V. and Coletta,M.
    pH- and temperature-dependence of functional modulation in metalloproteinases. A comparison between neutrophil collagenase and gelatinases A and B
    Biophys J79, 2138-2149. PubMed  Europe PubMed DOI
  73. [YEAR:7-9-2000]Gavuzzo,E., Pochetti,G., Mazza,F., Gallina,C., Gorini,B., D'Alessio,S., Pieper,M., Tschesche,H. and Tucker,P.A.
    Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: implications for drug design
    J Med Chem43, 3377-3385. PubMed  Europe PubMed DOI  S  I
  74. [YEAR:23-6-2000]Marini,S., Fasciglione,G.F., De Sanctis,G., D'Alessio,S., Politi,V. and Coletta,M.
    Cleavage of bovine collagen I by neutrophil collagenase MMP-8. Effect of pH on the catalytic properties as compared to synthetic substrates
    J Biol Chem275, 18657-18663. PubMed  Europe PubMed DOI
  75. Siller-Lopez,F., Garcia-Banuelos,J., Hasty,K.A., Segura,J., Ramos-Marquez,M., Qoronfleh,M.W., Aguilar-Cordova,E. and Armendariz-Borunda,J.
    Truncated active matrix metalloproteinase-8 gene expression in HepG2 cells is active against native type I collagen
    J Hepatol33, 758-763. PubMed  Europe PubMed DOI
    76. 1999
  76. [YEAR:1-6-1999]Farr,M., Pieper,M., Calvete,J. and Tschesche,H.
    The N-terminus of collagenase MMP-8 determines superactivity and inhibition: A relation of structure and function analyzed by biomolecular interaction analysis
    Biochemistry38, 7332-7338. PubMed  Europe PubMed DOI
  77. [YEAR:22-1-1999]Hu,S.I., Klein,M., Carozza,M., Rediske,J., Peppard,J. and Qi,J.S.
    Identification of a splice variant of neutrophil collagenase (MMP-8)
    FEBS Lett443, 8-10. PubMed  Europe PubMed DOI
  78. [YEAR:3-6-1999]Matter,H., Schwab,W., Barbier,D., Billen,G., Haase,B., Neises,B., Schudok,M., Thorwart,W., Schreuder,H., Brachvogel,V., Lonze,P. and Weithmann,K.U.
    Quantitative structure-activity relationship of human neutrophil collagenase (MMP-8) inhibitors using comparative molecular field analysis and X-ray structure analysis
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