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Literature for peptidase M02.004: angiotensin-converting enzyme peptidase unit 2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: A Assay, S Structure, K Knockout, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Shibata,T., Bhat,S.A., Cao,D., Saito,S., Bernstein,E.A., Nishi,E., Medenilla,J.D., Wang,E.T., Chan,J.L., Pisarska,M.D., Tourtellotte,W.G., Giani,J.F., Bernstein,K.E. and Khan,Z.
    Testicular ACE regulates sperm metabolism and fertilization through the transcription factor PPARgamma
    J Biol Chem300, 105486-105486. PubMed  Europe PubMed DOI
    2. 2021
  2. Alves-Lopes,R., Montezano,A.C., Neves,K.B., Harvey,A., Rios,F.J., Skiba,D.S., Arendse,L.B., Guzik,T.J., Graham,D., Poglitsch,M., Sturrock,E. and Touyz,R.M.
    Selective Inhibition of the C-Domain of ACE (Angiotensin-Converting Enzyme) Combined With Inhibition of NEP (Neprilysin): A Potential New Therapy for Hypertension
    Hypertension78, 604-616. PubMed  Europe PubMed DOI
    3. 2019
  3. Khan,Z., Cao,D.Y., Giani,J.F., Bernstein,E.A., Veiras,L.C., Fuchs,S., Wang,Y., Peng,Z., Kalkum,M., Liu,G.Y. and Bernstein,K.E.
    Overexpression of the C-domain of angiotensin-converting enzyme reduces melanoma growth by stimulating M1 macrophage polarization
    J Biol Chem294, 4368-4380. PubMed  Europe PubMed DOI
    4. 2018
  4. Cozier,G.E., Arendse,L.B., Schwager,S.L., Sturrock,E.D. and Acharya,K.R.
    Molecular basis for multiple omapatrilat binding sites within the ACE C-domain: implications for drug design
    J Med Chem61, 10141-10154. PubMed  Europe PubMed DOI  I
    5. 2017
  5. Yan,H.Y., Mita,K., Zhao,X., Tanaka,Y., Moriyama,M., Wang,H., Iwanaga,M. and Kawasaki,H.
    The angiotensin-converting enzyme (ACE) gene family of Bombyx mori
    Gene608, 58-65. PubMed  Europe PubMed DOI
    6. 2016
  6. Larmuth,K.M., Masuyer,G., Douglas,R.G., Schwager,S.L., Acharya,K.R. and Sturrock,E.D.
    Kinetic and structural characterization of amyloid-beta peptide hydrolysis by human angiotensin-1-converting enzyme
    FEBS J283, 1060-1076. PubMed  Europe PubMed DOI  S
    7. 2015
  7. Lunow,D., Kaiser,S., Ruckriemen,J., Pohl,C. and Henle,T.
    Tryptophan-containing dipeptides are C-domain selective inhibitors of angiotensin converting enzyme
    Food Chem166, 596-602. PubMed  Europe PubMed DOI  I
    8. 2014
  8. Kramer,G.J., Mohd,A., Schwager,S.L.U., Masuyer,G., Acharya,K.R., Sturrock,E.D. and Bachmann,B.O.
    Interkingdom pharmacology of angiotensin-I converting enzyme inhibitor phosphonates produced by actinomycetes
    ACS Med Chem Lett5, 346-351. PubMed  Europe PubMed DOI  S  I
  9. Masuyer,G., Akif,M., Czarny,B., Beau,F., Schwager,S.L., Sturrock,E.D., Isaac,R.E., Dive,V. and Acharya,K.R.
    Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme
    FEBS J281, 943-956. PubMed  Europe PubMed DOI  S  I
  10. Yates,C.J., Masuyer,G., Schwager,S.L., Akif,M., Sturrock,E.D. and Acharya,K.R.
    Molecular and thermodynamic mechanisms of the chloride-dependent human angiotensin-I-converting enzyme (ACE)
    J Biol Chem289, 1798-1814. PubMed  Europe PubMed DOI  S
    11. 2013
  11. Ehlers,M.R., Abrie,J.A. and Sturrock,E.D.
    C domain-selective inhibition of angiotensin-converting enzyme
    J Renin Angiotensin Aldosterone Syst14, 189-192. PubMed  Europe PubMed DOI  I
  12. Hocharoen,L., Joyner,J.C. and Cowan,J.A.
    N- versus C-domain selectivity of catalytic inactivation of human angiotensin converting enzyme by lisinopril-coupled transition metal chelates
    J Med Chem56, 9826-9836. PubMed  Europe PubMed DOI  I
  13. Zhang,C., Wu,S. and Xu,D.
    Catalytic Mechanism of Angiotensin-Converting Enzyme and Effects of the Chloride Ion
    J Phys Chem B117, 6635-6645. PubMed  Europe PubMed DOI
    14. 2012
  14. Sturrock,E.D., Anthony,C.S. and Danilov,S.M.
    Peptidyl-dipeptidase A/angiotensin I-converting enzyme
    [ISSN:978-0-12-407744-7]3, 480-494. DOI
  15. Zhou,M., Du,K., Ji,P. and Feng,W.
    Molecular mechanism of the interactions between inhibitory tripeptides and angiotensin-converting enzyme
    Biophys Chem168-169, 60-66. PubMed  Europe PubMed DOI  I
    16. 2011
  16. Akif,M., Schwager,S.L., Anthony,C.S., Czarny,B., Beau,F., Dive,V., Sturrock,E.D. and Acharya,K.R.
    Novel mechanism of inhibition of human angiotensin-I-converting enzyme (ACE) by a highly specific phosphinic tripeptide
    Biochem J436, 53-59. PubMed  Europe PubMed DOI  S  I
  17. Akif,M., Masuyer,G., Schwager,S.L., Bhuyan,B.J., Mugesh,G., Isaac,R.E., Sturrock,E.D. and Acharya,K.R.
    Structural characterization of angiotensin I-converting enzyme in complex with a selenium analogue of captopril
    FEBS J278, 3644-3650. PubMed  Europe PubMed DOI  S  I
  18. Bernstein,K.E., Shen,X.Z., Gonzalez-Villalobos,R.A., Billet,S., Okwan-Duodu,D., Ong,F.S. and Fuchs,S.
    Different in vivo functions of the two catalytic domains of angiotensin-converting enzyme (ACE)
    Curr Opin Pharmacol11, 105-111. PubMed  Europe PubMed DOI
  19. Wang,X., Wu,S., Xu,D., Xie,D. and Guo,H.
    Inhibitor and substrate binding by angiotensin-converting enzyme: quantum mechanical/molecular mechanical molecular dynamics studies
    J Chem Inf Model51, 1074-1082. PubMed  Europe PubMed DOI  I
    20. 2010
  20. Jullien,N., Makritis,A., Georgiadis,D., Beau,F., Yiotakis,A. and Dive,V.
    Phosphinic tripeptides as dual angiotensin-converting enzyme C-domain and endothelin-converting enzyme-1 inhibitors
    J Med Chem53, 208-220. PubMed  Europe PubMed DOI  I
  21. Spyranti,Z., Galanis,A.S., Pairas,G., Spyroulias,G.A., Manessi-Zoupa,E. and Cordopatis,P.
    Synthetic peptides as structural maquettes of angiotensin-I converting enzyme catalytic sites
    Bioinorg Chem Appl820476-820476. PubMed  Europe PubMed DOI
  22. Sun,X., Rentzsch,B., Gong,M., Eichhorst,J., Pankow,K., Papsdorf,G., Maul,B., Bader,M. and Siems,W.E.
    Signal transduction in CHO cells stably transfected with domain-selective forms of murine ACE
    Biol Chem391, 235-244. PubMed  Europe PubMed DOI
  23. Watermeyer,J., Kroger,W.L., Sturrock,E.D. and Ehlers,M.R.
    Angiotensin-converting enzyme - new insights into structure, biological significance and prospects for domain-selective inhibitors
    Curr Enzyme Inhib5, 134-147.
  24. Watermeyer,J.M., Kroger,W.L., O'Neill,H.G., Sewell,B.T. and Sturrock,E.D.
    Characterization of domain-selective inhibitor binding in angiotensin-converting enzyme using a novel derivative of lisinopril
    Biochem J428, 67-74. PubMed  Europe PubMed DOI  S  I
  25. Zhao,Y., Xu,J. and Xu,C.
    [Expression of human angiotensin converting enzyme-C domain in Pichia pastoris]
    Sheng Wu Gong Cheng Xue Bao26, 664-670. PubMed  Europe PubMed  E
    26. 2009
  26. Kroger,W.L., Douglas,R.G., O'Neill,H.G., Dive,V. and Sturrock,E.D.
    Investigating the domain specificity of phosphinic inhibitors RXPA380 and RXP407 in angiotensin-converting enzyme
    Biochemistry48, 8405-8412. PubMed  Europe PubMed DOI  I
  27. Simunic,J., Soyez,D. and Kamech,N.
    Characterization of a membrane-bound angiotensin-converting enzyme isoform in crayfish testis and evidence for its release into the seminal fluid
    FEBS J276, 4727-4738. PubMed  Europe PubMed DOI
  28. Vamvakas,S.S., Leondiadis,L., Pairas,G., Manessi-Zoupa,E., Spyroulias,G.A. and Cordopatis,P.
    Folding in solution of the C-catalytic protein fragment of angiotensin-converting enzyme
    J Pept Sci15, 504-510. PubMed  Europe PubMed DOI
  29. Zou,K., Maeda,T., Watanabe,A., Liu,J., Liu,S., Oba,R., Satoh,Y., Komano,H. and Michikawa,M.
    Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme
    J Biol Chem284, 31914-31920. PubMed  Europe PubMed DOI
    30. 2008
  30. Danilov,S.M., Balyasnikova,I.V., Albrecht,R.F. and Kost,O.A.
    Simultaneous determination of ACE activity with 2 substrates provides information on the status of somatic ACE and allows detection of inhibitors in human blood
    J Cardiovasc Pharmacol52, 90-103. PubMed  Europe PubMed DOI  A
  31. Fuchs,S., Xiao,H.D., Hubert,C., Michaud,A., Campbell,D.J., Adams,J.W., Capecchi,M.R., Corvol,P. and Bernstein,K.E.
    Angiotensin-converting enzyme C-terminal catalytic domain is the main site of angiotensin I cleavage in vivo
    Hypertension51, 267-274. PubMed  Europe PubMed DOI
  32. O'Neill,H.G., Redelinghuys,P., Schwager,S.L. and Sturrock,E.D.
    The role of glycosylation and domain interactions in the thermal stability of human angiotensin-converting enzyme
    Biol Chem389, 1153-1161. PubMed  Europe PubMed DOI
  33. Rushworth,C.A., Guy,J.L. and Turner,A.J.
    Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis
    FEBS J275, 6033-6042. PubMed  Europe PubMed DOI  I
  34. Watermeyer,J.M., Kroger,W.L., O'Neill,H.G., Sewell,B.T. and Sturrock,E.D.
    Probing the basis of domain-dependent inhibition using novel ketone inhibitors of angiotensin-converting enzyme
    Biochemistry47, 5942-5950. PubMed  Europe PubMed DOI  I
    35. 2007
  35. Corradi,H.R., Chitapi,I., Sewell,B.T., Georgiadis,D., Dive,V., Sturrock,E.D. and Acharya,K.R.
    The structure of testis angiotensin-converting enzyme in complex with the C domain-specific inhibitor RXPA380
    Biochemistry46, 5473-5478. PubMed  Europe PubMed DOI  S  I
    36. 2006
  36. [YEAR:19-12-2006]Bernstein,K.E.
    Views of the renin-angiotensin system: brilling, mimsy, and slithy tove
    Hypertension47, 509-514. PubMed  Europe PubMed DOI  V
  37. Carmona,A.K., Schwager,S.L., Juliano,M.A., Juliano,L. and Sturrock,E.D.
    A continuous fluorescence resonance energy transfer angiotensin I-converting enzyme assay
    Nat Protoc1, 1971-1976. PubMed  Europe PubMed DOI  A
  38. Kohlstedt,K., Gershome,C., Friedrich,M., Muller-Esterl,W., Alhenc-Gelas,F., Busse,R. and Fleming,I.
    Angiotensin-converting enzyme (ACE) dimerization is the initial step in the ACE inhibitor-induced ACE signaling cascade in endothelial cells
    Mol Pharmacol69, 1725-1732. PubMed  Europe PubMed DOI
  39. [YEAR:13-3-2006]Kugaevskaya,E.V., Kolesanova,E.F., Kozin,S.A., Veselovsky,A.V., Dedinsky,I.R. and Elisseeva,Y.E.
    Epitope mapping of the domains of human angiotensin converting enzyme
    Biochim Biophys Acta1760, 959-965. PubMed  Europe PubMed DOI
  40. Nchinda,A.T., Chibale,K., Redelinghuys,P. and Sturrock,E.D.
    Synthesis of novel keto-ACE analogues as domain-selective angiotensin I-converting enzyme inhibitors
    Bioorg Med Chem Lett16, 4612-4615. PubMed  Europe PubMed DOI  I
  41. Nchinda,A.T., Chibale,K., Redelinghuys,P. and Sturrock,E.D.
    Synthesis and molecular modeling of a lisinopril-tryptophan analogue inhibitor of angiotensin I-converting enzyme
    Bioorg Med Chem Lett16, 4616-4619. PubMed  Europe PubMed DOI  I
  42. Schwager,S.L., Carmona,A.K. and Sturrock,E.D.
    A high-throughput fluorimetric assay for angiotensin I-converting enzyme
    Nat Protoc1, 1961-1964. PubMed  Europe PubMed DOI  A
  43. [YEAR:18-4-2006]Skirgello,O.E., Balyasnikova,I.V., Binevski,P.V., Sun,Z.L., Baskin,I.I., Palyulin,V.A., Nesterovitch,A.B., Albrecht,R.F., Kost,O.A. and Danilov,S.M.
    Inhibitory antibodies to human angiotensin-converting enzyme: fine epitope mapping and mechanism of action
    Biochemistry45, 4831-4847. PubMed  Europe PubMed DOI
  44. Watermeyer,J.M., Sewell,B.T., Schwager,S.L., Natesh,R., Corradi,H.R., Acharya,K.R. and Sturrock,E.D.
    Structure of testis ACE glycosylation mutants and evidence for conserved domain movement
    Biochemistry45, 12654-12663. PubMed  Europe PubMed DOI  S
    45. 2005
  45. Alves,M.F., Araujo,M.C., Juliano,M.A., Oliveira,E.M., Krieger,J.E., Casarini,D.E., Juliano,L. and Carmona,A.K.
    A continuous fluorescent assay for the determination of plasma and tissue angiotensin I-converting enzyme activity
    Braz J Med Biol Res38, 861-868. PubMed  Europe PubMed DOI  A
  46. Balyasnikova,I.V., Woodman,Z.L., Albrecht,R.F., Natesh,R., Acharya,K.R., Sturrock,E.D. and Danilov,S.M.
    Localization of an N-domain region of angiotensin-converting enzyme involved in the regulation of ectodomain shedding using monoclonal antibodies
    J Proteome Res4, 258-267. PubMed  Europe PubMed DOI
  47. [YEAR:21-12-2005]Naqvi,N., Liu,K., Graham,R.M. and Husain,A.
    Molecular basis of exopeptidase activity in the C-terminal domain of human angiotensin I-converting enzyme: insights into the origins of its exopeptidase activity
    J Biol Chem280, 6669-6675. PubMed  Europe PubMed DOI
  48. Redelinghuys,P., Nchinda,A.T. and Sturrock,E.D.
    Development of domain-selective angiotensin I-converting enzyme inhibitors
    Ann N Y Acad Sci1056, 160-175. PubMed  Europe PubMed DOI  V
    49. 2004
  49. Bersanetti,P.A., Andrade,M.C., Casarini,D.E., Juliano,M.A., Nchinda,A.T., Sturrock,E.D., Juliano,L. and Carmona,A.K.
    Positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides for defining substrate specificity of the angiotensin I-converting enzyme and development of selective C-domain substrates
    Biochemistry43, 15729-15736. PubMed  Europe PubMed DOI  P
  50. Corvol,P., Eyries,M. and Soubrier,F.
    Peptidyl-dipeptidase A/angiotensin I-converting enzyme
    [ISSN:0-12-079610-4]2, 332-346.  V
  51. Georgiadis,D., Cuniasse,P., Cotton,J., Yiotakis,A. and Dive,V.
    Structural determinants of RXPA380, a potent and highly selective inhibitor of the angiotensin-converting enzyme C-domain
    Biochemistry43, 8048-8054. PubMed  Europe PubMed DOI  I
  52. Inguimbert,N., Poras,H., Dhotel,H., Beslot,F., Scalbert,E., Bennejean,C., Renard,P., Fournie-Zaluski,M.C. and Roques,B.P.
    In vivo properties of thiol inhibitors of the three vasopeptidases NEP, ACE and ECE are improved by introduction of a 7-azatryptophan in P2' position
    J Pept Res63, 99-107. PubMed  Europe PubMed DOI  I
  53. [YEAR:13-7-2004]Natesh,R., Schwager,S.L., Evans,H.R., Sturrock,E.D. and Acharya,K.R.
    Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme
    Biochemistry43, 8718-8724. PubMed  Europe PubMed DOI  S  I
  54. Spyroulias,G.A., Galanis,A.S., Pairas,G., Manessi-Zoupa,E. and Cordopatis,P.
    Structural features of angiotensin-I converting enzyme catalytic sites: conformational studies in solution, homology models and comparison with other zinc metallopeptidases
    Curr Top Med Chem4, 403-429. PubMed  Europe PubMed DOI
  55. Sturrock,E.D., Natesh,R., van Rooyen,J.M. and Acharya,K.R.
    Structure of angiotensin I-converting enzyme
    Cell Mol Life Sci61, 2677-2686. PubMed  Europe PubMed DOI  V  S  I
    56. 2003
  56. [YEAR:28-8-2003]Binevski,P.V., Sizova,E.A., Pozdnev,V.F. and Kost,O.A.
    Evidence for the negative cooperativity of the two active sites within bovine somatic angiotensin-converting enzyme
    FEBS Lett550, 84-88. PubMed  Europe PubMed DOI  I
  57. Brew,K.
    Structure of human ACE gives new insights into inhibitor binding and design
    Trends Pharmacol Sci24, 391-394. PubMed  Europe PubMed DOI  S
  58. [YEAR:22-8-2003]Fernandez,J.H., Hayashi,M.A., Camargo,A.C. and Neshich,G.
    Structural basis of the lisinopril-binding specificity in N- and C-domains of human somatic ACE
    Biochem Biophys Res Commun308, 219-226. PubMed  Europe PubMed DOI
  59. [YEAR:15-4-2003]Gordon,K., Redelinghuys,P., Schwager,S.L., Ehlers,M.R., Papageorgiou,A.C., Natesh,R., Acharya,K.R. and Sturrock,E.D.
    Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme
    Biochem J371, 437-442. PubMed  Europe PubMed DOI
  60. [YEAR:30-1-2003]Natesh,R., Schwager,S.L., Sturrock,E.D. and Acharya,K.R.
    Crystal structure of the human angiotensin-converting enzyme-lisinopril complex
    Nature421, 551-554. PubMed  Europe PubMed DOI  S  I
  61. Tzakos,A.G., Galanis,A.S., Spyroulias,G.A., Cordopatis,P., Manessi-Zoupa,E. and Gerothanassis,I.P.
    Structure-function discrimination of the N- and C- catalytic domains of human angiotensin-converting enzyme: implications for Cl- activation and peptide hydrolysis mechanisms
    Protein Eng16, 993-1003. PubMed  Europe PubMed DOI
    62. 2002
  62. Chubb,A.J., Schwager,S.L., Woodman,Z.L., Ehlers,M.R. and Sturrock,E.D.
    Defining the boundaries of the testis angiotensin I-converting enzyme ectodomain
    Biochem Biophys Res Commun297, 1225-1230. PubMed  Europe PubMed DOI
  63. [YEAR:14-5-2002]Cotton,J., Hayashi,M.A., Cuniasse,P., Vazeux,G., Ianzer,D., de Camargo,A.C. and Dive,V.
    Selective inhibition of the C-domain of angiotensin I converting enzyme by bradykinin potentiating peptides
    Biochemistry41, 6065-6071. PubMed  Europe PubMed DOI
  64. Hens,K., Vandingenen,A., Macours,N., Baggerman,G., Karaoglanovic,A.C., Schoofs,L., De Loof,A. and Huybrechts,R.
    Characterization of four substrates emphasizes kinetic similarity between insect and human C-domain angiotensin-converting enzyme
    Eur J Biochem269, 3522-3530. PubMed  Europe PubMed DOI
  65. [YEAR:8-2-2002]Kessler,S.P., Gomos,J.B., Scheidemantel,T.S., Rowe,T.M., Smith,H.L. and Sen,G.C.
    The germinal isozyme of angiotensin-converting enzyme can substitute for the somatic isozyme in maintaining normal renal structure and functions
    J Biol Chem277, 4271-4276. PubMed  Europe PubMed DOI
  66. Metayer,S., Dacheux,F., Dacheux,J.L. and Gatti,J.L.
    Germinal angiotensin I-converting enzyme is totally shed from the rodent sperm membrane during epididymal maturation
    Biol Reprod67, 1763-1767. PubMed  Europe PubMed DOI
  67. Voronov,S., Zueva,N., Orlov,V., Arutyunyan,A. and Kost,O.
    Temperature-induced selective death of the C-domain within angiotensin-converting enzyme molecule
    FEBS Lett522, 77-82. PubMed  Europe PubMed DOI
    68. 2001
  68. [YEAR:16-2-2001]Fernandez,M., Liu,X., Wouters,M.A., Heyberger,S. and Husain,A.
    Angiotensin I-converting enzyme transition state stabilization by His1089: evidence for a catalytic mechanism distinct from other gluzincin metalloproteinases
    J Biol Chem276, 4998-5004. PubMed  Europe PubMed DOI
  69. Kamata,M., Hu,J.G., Shibahara,H. and Nakagawa,H.
    Assay of testicular angiotensin-converting enzyme activity in human spermatozoa
    Int J Androl24, 225-231. PubMed  Europe PubMed DOI  A
  70. [YEAR:7-9-2001]Liu,X., Fernandez,M., Wouters,M.A., Heyberger,S. and Husain,A.
    Arg(1098) is critical for the chloride dependence of human angiotensin I-converting enzyme C-domain catalytic activity
    J Biol Chem276, 33518-33525. PubMed  Europe PubMed DOI
  71. Menard,J. and Patchett,A.A.
    Angiotensin-converting enzyme inhibitors
    Adv Protein Chem56, 13-75. PubMed  Europe PubMed DOI  V  I
  72. Sabeur,K., Vo,A.T. and Ball,B.A.
    Characterization of angiotensin-converting enzyme in canine testis
    Reproduction122, 139-146. PubMed  Europe PubMed
    73. 2000
  73. [YEAR:25-7-2000]Araujo,M.C., Melo,R.L., Cesari,M.H., Juliano,M.A., Juliano,L. and Carmona,A.K.
    Peptidase specificity characterization of C- and N-terminal catalytic sites of angiotensin I-converting enzyme
    Biochemistry39, 8519-8525. PubMed  Europe PubMed DOI
  74. Azizi,M., Massien,C., Michaud,A. and Corvol,P.
    In vitro and in vivo inhibition of the 2 active sites of ACE by omapatrilat, a vasopeptidase inhibitor
    Hypertension35, 1226-1231. PubMed  Europe PubMed  I
  75. [YEAR:1-8-2000]Coates,D., Isaac,R.E., Cotton,J., Siviter,R., Williams,T.A., Shirras,A., Corvol,P. and Dive,V.
    Functional conservation of the active sites of human and Drosophila angiotensin I-converting enzyme
    Biochemistry39, 8963-8969. PubMed  Europe PubMed DOI  I
  76. [YEAR:25-8-2000]Kessler,S.P., Rowe,T.M., Gomos,J.B., Kessler,P.M. and Sen,G.C.
    Physiological non-equivalence of the two isoforms of angiotensin-converting enzyme
    J Biol Chem275, 26259-26264. PubMed  Europe PubMed DOI
    77. 1999
  77. [YEAR:30-6-1999]Amour,A., Hutton,M., Knauper,V., Slocombe,P.M., Webster,A., Butler,M., Knight,C.G., Smith,B.J., Docherty,A.J. and Murphy,G.
    Inhibition of the metalloproteinase domain of mouse TACE
    Ann N Y Acad Sci878, 728-731. PubMed  Europe PubMed DOI
  78. [YEAR:13-4-1999]Dive,V., Cotton,J., Yiotakis,A., Michaud,A., Vassiliou,S., Jiracek,J., Vazeux,G., Chauvet,M.T., Cuniasse,P. and Corvol,P.
    RXP 407, a phosphinic peptide, is a potent inhibitor of angiotensin I converting enzyme able to differentiate between its two active sites
    Proc Natl Acad Sci U S A96, 4330-4335. PubMed  Europe PubMed DOI  I
  79. [YEAR:15-3-1999]Michaud,A., Chauvet,M.T. and Corvol,P.
    N-domain selectivity of angiotensin I-converting enzyme as assessed by structure-function studies of its highly selective substrate, N-acetyl-seryl-aspartyl-lysyl-proline
    Biochem Pharmacol57, 611-618. PubMed  Europe PubMed DOI
    80. 1998
  80. Deddish,P.A., Marcic,B., Jackman,H.L., Wang,H.Z., Skidgel,R.A. and Erdos,E.G.
    N-domain-specific substrate and C-domain inhibitors of angiotensin-converting enzyme: angiotensin-(1-7) and keto-ACE
    Hypertension31, 912-917. PubMed  Europe PubMed  I
  81. [YEAR:3-3-1998]Hagaman,J.R., Moyer,J.S., Bachman,E.S., Sibony,M., Magyar,P.L., Welch,J.E., Smithies,O., Krege,J.H. and O'Brien,D.A.
    Angiotensin-converting enzyme and male fertility
    Proc Natl Acad Sci U S A95, 2552-2557. PubMed  Europe PubMed DOI  K
  82. [YEAR:15-7-1998]Ramaraj,P., Kessler,S.P., Colmenares,C. and Sen,G.C.
    Selective restoration of male fertility in mice lacking angiotensin-converting enzymes by sperm-specific expression of the testicular isozyme
    J Clin Invest102, 371-378. PubMed  Europe PubMed DOI  K
    83. 1997
  83. Deddish,P.A., Jackman,H.L., Skidgel,R.A. and Erdos,E.G.
    Differences in the hydrolysis of enkephalin congeners by the two domains of angiotensin converting enzyme
    Biochem Pharmacol53, 1459-1463. PubMed  Europe PubMed DOI
  84. Esther,C.R., Marino,E.M., Howard,T.E., Machaud,A., Corvol,P., Capecchi,M.R. and Bernstein,K.E.
    The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice
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