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Literature for peptidase M02.004: angiotensin-converting enzyme peptidase unit 2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: A Assay, S Structure, K Knockout, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Cozier,G.E., Coulson,L.B., Eyermann,C.J., Basarab,G.S., Schwager,S.L., Chibale,K., Sturrock,E.D. and Acharya,K.R.
    Design of Novel Mercapto-3-phenylpropanoyl Dipeptides as Dual Angiotensin-Converting Enzyme C-Domain-Selective/Neprilysin Inhibitors
    J Med Chem (2025) 68, 7720-7736. PubMed  Europe PubMed DOI
  2. Gregory,K.S., Ramasamy,V., Sturrock,E.D. and Acharya,K.R.
    Ciprofloxacin Inhibits Angiotensin Iƒ_'Converting Enzyme (ACE) Activity by Binding at the Exosite, Distal to the Catalytic Pocket
    ACS Bio Med Chem Au (2025) 5, 852-859. PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2024
  3. Shibata,T., Bhat,S.A., Cao,D., Saito,S., Bernstein,E.A., Nishi,E., Medenilla,J.D., Wang,E.T., Chan,J.L., Pisarska,M.D., Tourtellotte,W.G., Giani,J.F., Bernstein,K.E. and Khan,Z.
    Testicular ACE regulates sperm metabolism and fertilization through the transcription factor PPARgamma
    J Biol Chem (2024) 300, 105486-105486. PubMed  Europe PubMed DOI  PMC  EPMC
    4. 2021
  4. Alves-Lopes,R., Montezano,A.C., Neves,K.B., Harvey,A., Rios,F.J., Skiba,D.S., Arendse,L.B., Guzik,T.J., Graham,D., Poglitsch,M., Sturrock,E. and Touyz,R.M.
    Selective Inhibition of the C-Domain of ACE (Angiotensin-Converting Enzyme) Combined With Inhibition of NEP (Neprilysin): A Potential New Therapy for Hypertension
    Hypertension (2021) 78, 604-616. PubMed  Europe PubMed DOI
    5. 2019
  5. Khan,Z., Cao,D.Y., Giani,J.F., Bernstein,E.A., Veiras,L.C., Fuchs,S., Wang,Y., Peng,Z., Kalkum,M., Liu,G.Y. and Bernstein,K.E.
    Overexpression of the C-domain of angiotensin-converting enzyme reduces melanoma growth by stimulating M1 macrophage polarization
    J Biol Chem (2019) 294, 4368-4380. PubMed  Europe PubMed DOI
    6. 2018
  6. Cozier,G.E., Arendse,L.B., Schwager,S.L., Sturrock,E.D. and Acharya,K.R.
    Molecular basis for multiple omapatrilat binding sites within the ACE C-domain: implications for drug design
    J Med Chem (2018) 61, 10141-10154. PubMed  Europe PubMed DOI  I
    7. 2017
  7. Yan,H.Y., Mita,K., Zhao,X., Tanaka,Y., Moriyama,M., Wang,H., Iwanaga,M. and Kawasaki,H.
    The angiotensin-converting enzyme (ACE) gene family of Bombyx mori
    Gene (2017) 608, 58-65. PubMed  Europe PubMed DOI
    8. 2016
  8. Larmuth,K.M., Masuyer,G., Douglas,R.G., Schwager,S.L., Acharya,K.R. and Sturrock,E.D.
    Kinetic and structural characterization of amyloid-beta peptide hydrolysis by human angiotensin-1-converting enzyme
    FEBS J (2016) 283, 1060-1076. PubMed  Europe PubMed DOI  S
    9. 2015
  9. Lunow,D., Kaiser,S., Ruckriemen,J., Pohl,C. and Henle,T.
    Tryptophan-containing dipeptides are C-domain selective inhibitors of angiotensin converting enzyme
    Food Chem (2015) 166, 596-602. PubMed  Europe PubMed DOI  I
    10. 2014
  10. Kramer,G.J., Mohd,A., Schwager,S.L.U., Masuyer,G., Acharya,K.R., Sturrock,E.D. and Bachmann,B.O.
    Interkingdom pharmacology of angiotensin-I converting enzyme inhibitor phosphonates produced by actinomycetes
    ACS Med Chem Lett (2014) 5, 346-351. PubMed  Europe PubMed DOI  S  I
  11. Masuyer,G., Akif,M., Czarny,B., Beau,F., Schwager,S.L., Sturrock,E.D., Isaac,R.E., Dive,V. and Acharya,K.R.
    Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme
    FEBS J (2014) 281, 943-956. PubMed  Europe PubMed DOI  S  I
  12. Yates,C.J., Masuyer,G., Schwager,S.L., Akif,M., Sturrock,E.D. and Acharya,K.R.
    Molecular and thermodynamic mechanisms of the chloride-dependent human angiotensin-I-converting enzyme (ACE)
    J Biol Chem (2014) 289, 1798-1814. PubMed  Europe PubMed DOI  S
    13. 2013
  13. Ehlers,M.R., Abrie,J.A. and Sturrock,E.D.
    C domain-selective inhibition of angiotensin-converting enzyme
    J Renin Angiotensin Aldosterone Syst (2013) 14, 189-192. PubMed  Europe PubMed DOI  I
  14. Hocharoen,L., Joyner,J.C. and Cowan,J.A.
    N- versus C-domain selectivity of catalytic inactivation of human angiotensin converting enzyme by lisinopril-coupled transition metal chelates
    J Med Chem (2013) 56, 9826-9836. PubMed  Europe PubMed DOI  I
  15. Zhang,C., Wu,S. and Xu,D.
    Catalytic Mechanism of Angiotensin-Converting Enzyme and Effects of the Chloride Ion
    J Phys Chem B (2013) 117, 6635-6645. PubMed  Europe PubMed DOI
    16. 2012
  16. Sturrock,E.D., Anthony,C.S. and Danilov,S.M.
    Peptidyl-dipeptidase A/angiotensin I-converting enzyme
    [ISSN:978-0-12-407744-7] (2012) 3, 480-494. DOI
  17. Zhou,M., Du,K., Ji,P. and Feng,W.
    Molecular mechanism of the interactions between inhibitory tripeptides and angiotensin-converting enzyme
    Biophys Chem (2012) 168-169, 60-66. PubMed  Europe PubMed DOI  I
    18. 2011
  18. Akif,M., Masuyer,G., Schwager,S.L., Bhuyan,B.J., Mugesh,G., Isaac,R.E., Sturrock,E.D. and Acharya,K.R.
    Structural characterization of angiotensin I-converting enzyme in complex with a selenium analogue of captopril
    FEBS J (2011) 278, 3644-3650. PubMed  Europe PubMed DOI  S  I
  19. Akif,M., Schwager,S.L., Anthony,C.S., Czarny,B., Beau,F., Dive,V., Sturrock,E.D. and Acharya,K.R.
    Novel mechanism of inhibition of human angiotensin-I-converting enzyme (ACE) by a highly specific phosphinic tripeptide
    Biochem J (2011) 436, 53-59. PubMed  Europe PubMed DOI  S  I
  20. Bernstein,K.E., Shen,X.Z., Gonzalez-Villalobos,R.A., Billet,S., Okwan-Duodu,D., Ong,F.S. and Fuchs,S.
    Different in vivo functions of the two catalytic domains of angiotensin-converting enzyme (ACE)
    Curr Opin Pharmacol (2011) 11, 105-111. PubMed  Europe PubMed DOI
  21. Wang,X., Wu,S., Xu,D., Xie,D. and Guo,H.
    Inhibitor and substrate binding by angiotensin-converting enzyme: quantum mechanical/molecular mechanical molecular dynamics studies
    J Chem Inf Model (2011) 51, 1074-1082. PubMed  Europe PubMed DOI  I
    22. 2010
  22. Jullien,N., Makritis,A., Georgiadis,D., Beau,F., Yiotakis,A. and Dive,V.
    Phosphinic tripeptides as dual angiotensin-converting enzyme C-domain and endothelin-converting enzyme-1 inhibitors
    J Med Chem (2010) 53, 208-220. PubMed  Europe PubMed DOI  I
  23. Spyranti,Z., Galanis,A.S., Pairas,G., Spyroulias,G.A., Manessi-Zoupa,E. and Cordopatis,P.
    Synthetic peptides as structural maquettes of angiotensin-I converting enzyme catalytic sites
    Bioinorg Chem Appl (2010) , 820476-820476. PubMed  Europe PubMed DOI  PMC  EPMC
  24. Sun,X., Rentzsch,B., Gong,M., Eichhorst,J., Pankow,K., Papsdorf,G., Maul,B., Bader,M. and Siems,W.E.
    Signal transduction in CHO cells stably transfected with domain-selective forms of murine ACE
    Biol Chem (2010) 391, 235-244. PubMed  Europe PubMed DOI
  25. Watermeyer,J., Kroger,W.L., Sturrock,E.D. and Ehlers,M.R.
    Angiotensin-converting enzyme - new insights into structure, biological significance and prospects for domain-selective inhibitors
    Curr Enzyme Inhib (2010) 5, 134-147.
  26. Watermeyer,J.M., Kroger,W.L., O'Neill,H.G., Sewell,B.T. and Sturrock,E.D.
    Characterization of domain-selective inhibitor binding in angiotensin-converting enzyme using a novel derivative of lisinopril
    Biochem J (2010) 428, 67-74. PubMed  Europe PubMed DOI  S  I
  27. Zhao,Y., Xu,J. and Xu,C.
    [Expression of human angiotensin converting enzyme-C domain in Pichia pastoris]
    Sheng Wu Gong Cheng Xue Bao (2010) 26, 664-670. PubMed  Europe PubMed  E
    28. 2009
  28. Kroger,W.L., Douglas,R.G., O'Neill,H.G., Dive,V. and Sturrock,E.D.
    Investigating the domain specificity of phosphinic inhibitors RXPA380 and RXP407 in angiotensin-converting enzyme
    Biochemistry (2009) 48, 8405-8412. PubMed  Europe PubMed DOI  I
  29. Simunic,J., Soyez,D. and Kamech,N.
    Characterization of a membrane-bound angiotensin-converting enzyme isoform in crayfish testis and evidence for its release into the seminal fluid
    FEBS J (2009) 276, 4727-4738. PubMed  Europe PubMed DOI
  30. Vamvakas,S.S., Leondiadis,L., Pairas,G., Manessi-Zoupa,E., Spyroulias,G.A. and Cordopatis,P.
    Folding in solution of the C-catalytic protein fragment of angiotensin-converting enzyme
    J Pept Sci (2009) 15, 504-510. PubMed  Europe PubMed DOI
  31. Zou,K., Maeda,T., Watanabe,A., Liu,J., Liu,S., Oba,R., Satoh,Y., Komano,H. and Michikawa,M.
    Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme
    J Biol Chem (2009) 284, 31914-31920. PubMed  Europe PubMed DOI  PMC  EPMC
    32. 2008
  32. Danilov,S.M., Balyasnikova,I.V., Albrecht,R.F. and Kost,O.A.
    Simultaneous determination of ACE activity with 2 substrates provides information on the status of somatic ACE and allows detection of inhibitors in human blood
    J Cardiovasc Pharmacol (2008) 52, 90-103. PubMed  Europe PubMed DOI  A
  33. Fuchs,S., Xiao,H.D., Hubert,C., Michaud,A., Campbell,D.J., Adams,J.W., Capecchi,M.R., Corvol,P. and Bernstein,K.E.
    Angiotensin-converting enzyme C-terminal catalytic domain is the main site of angiotensin I cleavage in vivo
    Hypertension (2008) 51, 267-274. PubMed  Europe PubMed DOI
  34. O'Neill,H.G., Redelinghuys,P., Schwager,S.L. and Sturrock,E.D.
    The role of glycosylation and domain interactions in the thermal stability of human angiotensin-converting enzyme
    Biol Chem (2008) 389, 1153-1161. PubMed  Europe PubMed DOI
  35. Rushworth,C.A., Guy,J.L. and Turner,A.J.
    Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis
    FEBS J (2008) 275, 6033-6042. PubMed  Europe PubMed DOI  I
  36. Watermeyer,J.M., Kroger,W.L., O'Neill,H.G., Sewell,B.T. and Sturrock,E.D.
    Probing the basis of domain-dependent inhibition using novel ketone inhibitors of angiotensin-converting enzyme
    Biochemistry (2008) 47, 5942-5950. PubMed  Europe PubMed DOI  I
    37. 2007
  37. Corradi,H.R., Chitapi,I., Sewell,B.T., Georgiadis,D., Dive,V., Sturrock,E.D. and Acharya,K.R.
    The structure of testis angiotensin-converting enzyme in complex with the C domain-specific inhibitor RXPA380
    Biochemistry (2007) 46, 5473-5478. PubMed  Europe PubMed DOI  S  I
    38. 2006
  38. [YEAR:19-12-2006]Bernstein,K.E.
    Views of the renin-angiotensin system: brilling, mimsy, and slithy tove
    Hypertension (19-12-2006) 47, 509-514. PubMed  Europe PubMed DOI  V
  39. Carmona,A.K., Schwager,S.L., Juliano,M.A., Juliano,L. and Sturrock,E.D.
    A continuous fluorescence resonance energy transfer angiotensin I-converting enzyme assay
    Nat Protoc (2006) 1, 1971-1976. PubMed  Europe PubMed DOI  A
  40. Kohlstedt,K., Gershome,C., Friedrich,M., Muller-Esterl,W., Alhenc-Gelas,F., Busse,R. and Fleming,I.
    Angiotensin-converting enzyme (ACE) dimerization is the initial step in the ACE inhibitor-induced ACE signaling cascade in endothelial cells
    Mol Pharmacol (2006) 69, 1725-1732. PubMed  Europe PubMed DOI
  41. [YEAR:13-3-2006]Kugaevskaya,E.V., Kolesanova,E.F., Kozin,S.A., Veselovsky,A.V., Dedinsky,I.R. and Elisseeva,Y.E.
    Epitope mapping of the domains of human angiotensin converting enzyme
    Biochim Biophys Acta (13-3-2006) 1760, 959-965. PubMed  Europe PubMed DOI
  42. Nchinda,A.T., Chibale,K., Redelinghuys,P. and Sturrock,E.D.
    Synthesis and molecular modeling of a lisinopril-tryptophan analogue inhibitor of angiotensin I-converting enzyme
    Bioorg Med Chem Lett (2006) 16, 4616-4619. PubMed  Europe PubMed DOI  I
  43. Nchinda,A.T., Chibale,K., Redelinghuys,P. and Sturrock,E.D.
    Synthesis of novel keto-ACE analogues as domain-selective angiotensin I-converting enzyme inhibitors
    Bioorg Med Chem Lett (2006) 16, 4612-4615. PubMed  Europe PubMed DOI  I
  44. Schwager,S.L., Carmona,A.K. and Sturrock,E.D.
    A high-throughput fluorimetric assay for angiotensin I-converting enzyme
    Nat Protoc (2006) 1, 1961-1964. PubMed  Europe PubMed DOI  A
  45. [YEAR:18-4-2006]Skirgello,O.E., Balyasnikova,I.V., Binevski,P.V., Sun,Z.L., Baskin,I.I., Palyulin,V.A., Nesterovitch,A.B., Albrecht,R.F., Kost,O.A. and Danilov,S.M.
    Inhibitory antibodies to human angiotensin-converting enzyme: fine epitope mapping and mechanism of action
    Biochemistry (18-4-2006) 45, 4831-4847. PubMed  Europe PubMed DOI
  46. Watermeyer,J.M., Sewell,B.T., Schwager,S.L., Natesh,R., Corradi,H.R., Acharya,K.R. and Sturrock,E.D.
    Structure of testis ACE glycosylation mutants and evidence for conserved domain movement
    Biochemistry (2006) 45, 12654-12663. PubMed  Europe PubMed DOI  PMC  EPMC  S
    47. 2005
  47. Alves,M.F., Araujo,M.C., Juliano,M.A., Oliveira,E.M., Krieger,J.E., Casarini,D.E., Juliano,L. and Carmona,A.K.
    A continuous fluorescent assay for the determination of plasma and tissue angiotensin I-converting enzyme activity
    Braz J Med Biol Res (2005) 38, 861-868. PubMed  Europe PubMed DOI  A
  48. Balyasnikova,I.V., Woodman,Z.L., Albrecht,R.F., Natesh,R., Acharya,K.R., Sturrock,E.D. and Danilov,S.M.
    Localization of an N-domain region of angiotensin-converting enzyme involved in the regulation of ectodomain shedding using monoclonal antibodies
    J Proteome Res (2005) 4, 258-267. PubMed  Europe PubMed DOI
  49. [YEAR:21-12-2005]Naqvi,N., Liu,K., Graham,R.M. and Husain,A.
    Molecular basis of exopeptidase activity in the C-terminal domain of human angiotensin I-converting enzyme: insights into the origins of its exopeptidase activity
    J Biol Chem (21-12-2005) 280, 6669-6675. PubMed  Europe PubMed DOI
  50. Redelinghuys,P., Nchinda,A.T. and Sturrock,E.D.
    Development of domain-selective angiotensin I-converting enzyme inhibitors
    Ann N Y Acad Sci (2005) 1056, 160-175. PubMed  Europe PubMed DOI  V
    51. 2004
  51. Bersanetti,P.A., Andrade,M.C., Casarini,D.E., Juliano,M.A., Nchinda,A.T., Sturrock,E.D., Juliano,L. and Carmona,A.K.
    Positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides for defining substrate specificity of the angiotensin I-converting enzyme and development of selective C-domain substrates
    Biochemistry (2004) 43, 15729-15736. PubMed  Europe PubMed DOI  P
  52. Corvol,P., Eyries,M. and Soubrier,F.
    Peptidyl-dipeptidase A/angiotensin I-converting enzyme
    [ISSN:0-12-079610-4] (2004) 2, 332-346.  V
  53. Georgiadis,D., Cuniasse,P., Cotton,J., Yiotakis,A. and Dive,V.
    Structural determinants of RXPA380, a potent and highly selective inhibitor of the angiotensin-converting enzyme C-domain
    Biochemistry (2004) 43, 8048-8054. PubMed  Europe PubMed DOI  I
  54. Inguimbert,N., Poras,H., Dhotel,H., Beslot,F., Scalbert,E., Bennejean,C., Renard,P., Fournie-Zaluski,M.C. and Roques,B.P.
    In vivo properties of thiol inhibitors of the three vasopeptidases NEP, ACE and ECE are improved by introduction of a 7-azatryptophan in P2' position
    J Pept Res (2004) 63, 99-107. PubMed  Europe PubMed DOI  I
  55. [YEAR:13-7-2004]Natesh,R., Schwager,S.L., Evans,H.R., Sturrock,E.D. and Acharya,K.R.
    Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme
    Biochemistry (13-7-2004) 43, 8718-8724. PubMed  Europe PubMed DOI  S  I
  56. Spyroulias,G.A., Galanis,A.S., Pairas,G., Manessi-Zoupa,E. and Cordopatis,P.
    Structural features of angiotensin-I converting enzyme catalytic sites: conformational studies in solution, homology models and comparison with other zinc metallopeptidases
    Curr Top Med Chem (2004) 4, 403-429. PubMed  Europe PubMed DOI
  57. Sturrock,E.D., Natesh,R., van Rooyen,J.M. and Acharya,K.R.
    Structure of angiotensin I-converting enzyme
    Cell Mol Life Sci (2004) 61, 2677-2686. PubMed  Europe PubMed DOI  V  S  I
    58. 2003
  58. [YEAR:28-8-2003]Binevski,P.V., Sizova,E.A., Pozdnev,V.F. and Kost,O.A.
    Evidence for the negative cooperativity of the two active sites within bovine somatic angiotensin-converting enzyme
    FEBS Lett (28-8-2003) 550, 84-88. PubMed  Europe PubMed DOI  I
  59. Brew,K.
    Structure of human ACE gives new insights into inhibitor binding and design
    Trends Pharmacol Sci (2003) 24, 391-394. PubMed  Europe PubMed DOI  S
  60. [YEAR:22-8-2003]Fernandez,J.H., Hayashi,M.A., Camargo,A.C. and Neshich,G.
    Structural basis of the lisinopril-binding specificity in N- and C-domains of human somatic ACE
    Biochem Biophys Res Commun (22-8-2003) 308, 219-226. PubMed  Europe PubMed DOI
  61. [YEAR:15-4-2003]Gordon,K., Redelinghuys,P., Schwager,S.L., Ehlers,M.R., Papageorgiou,A.C., Natesh,R., Acharya,K.R. and Sturrock,E.D.
    Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme
    Biochem J (15-4-2003) 371, 437-442. PubMed  Europe PubMed DOI  PMC  EPMC
  62. [YEAR:30-1-2003]Natesh,R., Schwager,S.L., Sturrock,E.D. and Acharya,K.R.
    Crystal structure of the human angiotensin-converting enzyme-lisinopril complex
    Nature (30-1-2003) 421, 551-554. PubMed  Europe PubMed DOI  S  I
  63. Tzakos,A.G., Galanis,A.S., Spyroulias,G.A., Cordopatis,P., Manessi-Zoupa,E. and Gerothanassis,I.P.
    Structure-function discrimination of the N- and C- catalytic domains of human angiotensin-converting enzyme: implications for Cl- activation and peptide hydrolysis mechanisms
    Protein Eng (2003) 16, 993-1003. PubMed  Europe PubMed DOI
    64. 2002
  64. Chubb,A.J., Schwager,S.L., Woodman,Z.L., Ehlers,M.R. and Sturrock,E.D.
    Defining the boundaries of the testis angiotensin I-converting enzyme ectodomain
    Biochem Biophys Res Commun (2002) 297, 1225-1230. PubMed  Europe PubMed DOI
  65. [YEAR:14-5-2002]Cotton,J., Hayashi,M.A., Cuniasse,P., Vazeux,G., Ianzer,D., de Camargo,A.C. and Dive,V.
    Selective inhibition of the C-domain of angiotensin I converting enzyme by bradykinin potentiating peptides
    Biochemistry (14-5-2002) 41, 6065-6071. PubMed  Europe PubMed DOI
  66. Hens,K., Vandingenen,A., Macours,N., Baggerman,G., Karaoglanovic,A.C., Schoofs,L., De Loof,A. and Huybrechts,R.
    Characterization of four substrates emphasizes kinetic similarity between insect and human C-domain angiotensin-converting enzyme
    Eur J Biochem (2002) 269, 3522-3530. PubMed  Europe PubMed DOI
  67. [YEAR:8-2-2002]Kessler,S.P., Gomos,J.B., Scheidemantel,T.S., Rowe,T.M., Smith,H.L. and Sen,G.C.
    The germinal isozyme of angiotensin-converting enzyme can substitute for the somatic isozyme in maintaining normal renal structure and functions
    J Biol Chem (8-2-2002) 277, 4271-4276. PubMed  Europe PubMed DOI
  68. Metayer,S., Dacheux,F., Dacheux,J.L. and Gatti,J.L.
    Germinal angiotensin I-converting enzyme is totally shed from the rodent sperm membrane during epididymal maturation
    Biol Reprod (2002) 67, 1763-1767. PubMed  Europe PubMed DOI
  69. Voronov,S., Zueva,N., Orlov,V., Arutyunyan,A. and Kost,O.
    Temperature-induced selective death of the C-domain within angiotensin-converting enzyme molecule
    FEBS Lett (2002) 522, 77-82. PubMed  Europe PubMed DOI
    70. 2001
  70. [YEAR:16-2-2001]Fernandez,M., Liu,X., Wouters,M.A., Heyberger,S. and Husain,A.
    Angiotensin I-converting enzyme transition state stabilization by His1089: evidence for a catalytic mechanism distinct from other gluzincin metalloproteinases
    J Biol Chem (16-2-2001) 276, 4998-5004. PubMed  Europe PubMed DOI
  71. Kamata,M., Hu,J.G., Shibahara,H. and Nakagawa,H.
    Assay of testicular angiotensin-converting enzyme activity in human spermatozoa
    Int J Androl (2001) 24, 225-231. PubMed  Europe PubMed DOI  A
  72. [YEAR:7-9-2001]Liu,X., Fernandez,M., Wouters,M.A., Heyberger,S. and Husain,A.
    Arg(1098) is critical for the chloride dependence of human angiotensin I-converting enzyme C-domain catalytic activity
    J Biol Chem (7-9-2001) 276, 33518-33525. PubMed  Europe PubMed DOI
  73. Menard,J. and Patchett,A.A.
    Angiotensin-converting enzyme inhibitors
    Adv Protein Chem (2001) 56, 13-75. PubMed  Europe PubMed DOI  V  I
  74. Sabeur,K., Vo,A.T. and Ball,B.A.
    Characterization of angiotensin-converting enzyme in canine testis
    Reproduction (2001) 122, 139-146. PubMed  Europe PubMed
    75. 2000
  75. [YEAR:25-7-2000]Araujo,M.C., Melo,R.L., Cesari,M.H., Juliano,M.A., Juliano,L. and Carmona,A.K.
    Peptidase specificity characterization of C- and N-terminal catalytic sites of angiotensin I-converting enzyme
    Biochemistry (25-7-2000) 39, 8519-8525. PubMed  Europe PubMed DOI
  76. Azizi,M., Massien,C., Michaud,A. and Corvol,P.
    In vitro and in vivo inhibition of the 2 active sites of ACE by omapatrilat, a vasopeptidase inhibitor
    Hypertension (2000) 35, 1226-1231. PubMed  Europe PubMed  I
  77. [YEAR:1-8-2000]Coates,D., Isaac,R.E., Cotton,J., Siviter,R., Williams,T.A., Shirras,A., Corvol,P. and Dive,V.
    Functional conservation of the active sites of human and Drosophila angiotensin I-converting enzyme
    Biochemistry (1-8-2000) 39, 8963-8969. PubMed  Europe PubMed DOI  I
  78. [YEAR:25-8-2000]Kessler,S.P., Rowe,T.M., Gomos,J.B., Kessler,P.M. and Sen,G.C.
    Physiological non-equivalence of the two isoforms of angiotensin-converting enzyme
    J Biol Chem (25-8-2000) 275, 26259-26264. PubMed  Europe PubMed DOI
    79. 1999
  79. [YEAR:30-6-1999]Amour,A., Hutton,M., Knauper,V., Slocombe,P.M., Webster,A., Butler,M., Knight,C.G., Smith,B.J., Docherty,A.J. and Murphy,G.
    Inhibition of the metalloproteinase domain of mouse TACE
    Ann N Y Acad Sci (30-6-1999) 878, 728-731. PubMed  Europe PubMed DOI
  80. [YEAR:13-4-1999]Dive,V., Cotton,J., Yiotakis,A., Michaud,A., Vassiliou,S., Jiracek,J., Vazeux,G., Chauvet,M.T., Cuniasse,P. and Corvol,P.
    RXP 407, a phosphinic peptide, is a potent inhibitor of angiotensin I converting enzyme able to differentiate between its two active sites
    Proc Natl Acad Sci U S A (13-4-1999) 96, 4330-4335. PubMed  Europe PubMed DOI  PMC  EPMC  I
  81. [YEAR:15-3-1999]Michaud,A., Chauvet,M.T. and Corvol,P.
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