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Literature for peptidase M02.003: peptidyl-dipeptidase Ance

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Vecchie',D., Faber,V.G., Jumbo-Lucioni,P., Anholt,R.R.H., Mackay,T.F.C. and De Luca,M.
    Angiotensin-Converting Enzyme Inhibitors and Metabolic Aging: A Drosophila Perspective
    Biomolecules (2025) 15 PubMed  Europe PubMed DOI  PMC  EPMC
  2. Zukowska,J., Gregory,K.S., Robinson,A., Isaac,R.E. and Acharya,K.R.
    Molecular Basis of Dipeptide Recognition in Drosophila melanogaster Angiotensin I-Converting Enzyme Homologue, AnCE
    Biomolecules (2025) 15 PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2023
  3. Herrera,P. and Cauchi,R.J.
    Functional characterisation of the ACE2 orthologues in Drosophila provides insights into the neuromuscular complications of COVID-19
    Biochim Biophys Acta Mol Basis Dis (2023) 1869, 166818-166818. PubMed  Europe PubMed DOI  K
    4. 2022
  4. Duarte,T., Silva,M.M., Michelotti,P., Barbosa,N.B.V., Feltes,B.C., Dorn,M., Rocha,J.B.T.D. and Dalla Corte,C.L.
    The Drosophila melanogaster ACE2 ortholog genes are differently expressed in obesity/diabetes and aging models: Implications for COVID-19 pathology
    Biochim Biophys Acta Mol Basis Dis (2022) 1868, 166551-166551. PubMed  Europe PubMed DOI  PMC  EPMC
    5. 2019
  5. Cashman,J.S., Cozier,G.E., Harrison,C., Isaac,R.E. and Acharya,K.R.
    Crystal structures of angiotensin-converting enzyme from Anopheles gambiae in its native form and with a bound inhibitor
    Biochem J (2019) 476, 3505-3520. PubMed  Europe PubMed DOI  S
    6. 2017
  6. Kim,A.R., Choi,E.B., Kim,M.Y. and Choi,K.W.
    Angiotensin-converting enzyme Ance is cooperatively regulated by Mad and Pannier in Drosophila imaginal discs
    Sci Rep (2017) 7, 13174-13174. PubMed  Europe PubMed DOI  PMC  EPMC
    7. 2015
  7. Harrison,C. and Acharya,K.R.
    A new high-resolution crystal structure of the Drosophila melanogaster angiotensin converting enzyme homologue, AnCE
    FEBS Open Bio (2015) 5, 661-667. PubMed  Europe PubMed DOI  PMC  EPMC  S
    8. 2014
  8. Masuyer,G., Akif,M., Czarny,B., Beau,F., Schwager,S.L., Sturrock,E.D., Isaac,R.E., Dive,V. and Acharya,K.R.
    Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme
    FEBS J (2014) 281, 943-956. PubMed  Europe PubMed DOI  S  I
    9. 2012
  9. Akif,M., Masuyer,G., Bingham,R.J., Sturrock,E.D., Isaac,R.E. and Acharya,K.R.
    Structural basis of peptide recognition by the angiotensin-1 converting enzyme homologue AnCE from Drosophila melanogaster
    FEBS J (2012) 279, 4525-4534. PubMed  Europe PubMed DOI  S
  10. Isaac,R.E. and Shirras,A.D.
    Peptidyl-dipeptidase A (invertebrate)
    [ISSN:978-0-12-407744-7] (2012) 3, 494-498. DOI
    11. 2011
  11. Akif,M., Masuyer,G., Schwager,S.L., Bhuyan,B.J., Mugesh,G., Isaac,R.E., Sturrock,E.D. and Acharya,K.R.
    Structural characterization of angiotensin I-converting enzyme in complex with a selenium analogue of captopril
    FEBS J (2011) 278, 3644-3650. PubMed  Europe PubMed DOI  S  I
    12. 2010
  12. Akif,M., Georgiadis,D., Mahajan,A., Dive,V., Sturrock,E.D., Isaac,R.E. and Acharya,K.R.
    High-resolution crystal structures of Drosophila melanogaster angiotensin-converting enzyme in complex with novel inhibitors and antihypertensive drugs
    J Mol Biol (2010) 400, 502-517. PubMed  Europe PubMed DOI  S  I
  13. Akif,M., Ntai,I., Sturrock,E.D., Isaac,R.E., Bachmann,B.O. and Acharya,K.R.
    Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster
    Biochem Biophys Res Commun (2010) 398, 532-536. PubMed  Europe PubMed DOI  S  I
    14. 2008
  14. Lemeire,E., Vanholme,B., Van Leeuwen,T., Van Camp,J. and Smagghe,G.
    Angiotensin-converting enzyme in Spodoptera littoralis: molecular characterization, expression and activity profile during development
    Insect Biochem Mol Biol (2008) 38, 166-175. PubMed  Europe PubMed DOI
    15. 2007
  15. Isaac,R.E., Lamango,N.S., Ekbote,U., Taylor,C.A., Hurst,D., Weaver,R.J., Carhan,A., Burnham,S. and Shirras,A.D.
    Angiotensin-converting enzyme as a target for the development of novel insect growth regulators
    Peptides (2007) 28, 153-162. PubMed  Europe PubMed DOI
  16. Rylett,C.M., Walker,M.J., Howell,G.J., Shirras,A.D. and Isaac,R.E.
    Male accessory glands of Drosophila melanogaster make a secreted angiotensin I-converting enzyme (ANCE), suggesting a role for the peptide-processing enzyme in seminal fluid
    J Exp Biol (2007) 210, 3601-3606. PubMed  Europe PubMed DOI
  17. Yan,H.Y., Iwanaga,M. and Kawasaki,H.
    Angiotensin-converting enzyme activity in the hemolymph during last laval and pupal stages of the silkworm, Bombyx mori
    J Insect Biotechnol Sericology (2007) 76, 17-23.
    18. 2006
  18. Bingham,R.J., Dive,V., Phillips,S.E., Shirras,A.D. and Isaac,R.E.
    Structural diversity of angiotensin-converting enzyme - insights from structure-activity comparisons of two Drosophila enzymes
    FEBS J (2006) 273, 362-373. PubMed  Europe PubMed DOI
    19. 2005
  19. Burnham,S., Smith,J.A., Lee,A.J., Isaac,R.E. and Shirras,A.D.
    The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae
    BMC Genomics (2005) 6, 172-172. PubMed  Europe PubMed DOI  PMC  EPMC
    20. 2004
  20. Isaac,R.E.
    Peptidyl-dipeptidase A (invertebrate)
    [ISSN:0-12-079610-4] (2004) 2, 347-349.  V
  21. Macours,N. and Hens,K.
    Zinc-metalloproteases in insects: ACE and ECE
    Insect Biochem Mol Biol (2004) 34, 501-510. PubMed  Europe PubMed DOI
    22. 2003
  22. [YEAR:15-2-2003]Hurst,D., Rylett,C.M., Isaac,R.E. and Shirras,A.D.
    The Drosophila angiotensin-converting enzyme homologue Ance is required for spermiogenesis
    Dev Biol (15-2-2003) 254, 238-247. PubMed  Europe PubMed DOI
  23. [YEAR:13-3-2003]Kim,H.M., Shin,D.R., Yoo,O.J., Lee,H. and Lee,J.O.
    Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril
    FEBS Lett (13-3-2003) 538, 65-70. PubMed  Europe PubMed DOI  S  I
    24. 2002
  24. Siviter,R.J., Nachman,R.J., Dani,M.P., Keen,J.N., Shirras,A.D. and Isaac,R.E.
    Peptidyl dipeptidases (Ance and Acer) of Drosophila melanogaster: major differences in the substrate specificity of two homologs of human angiotensin I-converting enzyme
    Peptides (2002) 23, 2025-2034. PubMed  Europe PubMed DOI
  25. [YEAR:1-10-2002]Siviter,R.J., Taylor,C.A., Cottam,D.M., Denton,A., Dani,M.P., Milner,M.J., Shirras,A.D. and Isaac,R.E.
    Ance, a Drosophila angiotensin-converting enzyme homologue, is expressed in imaginal cells during metamorphosis and is regulated by the steroid, 20-hydroxyecdysone
    Biochem J (1-10-2002) 367, 187-193. PubMed  Europe PubMed DOI  PMC  EPMC
    26. 2001
  26. Vandingenen,A., Hens,K., Macours,N., Zhu,W., Janssen,I., Breuer,M., De Loof,A. and Huybrechts,R.
    Captopril, a specific inhibitor of angiotensin converting enzyme, enhances both trypsin and vitellogenin titers in the grey fleshfly Neobellieria bullata
    Arch Insect Biochem Physiol (2001) 47, 161-167. PubMed  Europe PubMed DOI  I
    27. 2000
  27. [YEAR:1-8-2000]Coates,D., Isaac,R.E., Cotton,J., Siviter,R., Williams,T.A., Shirras,A., Corvol,P. and Dive,V.
    Functional conservation of the active sites of human and Drosophila angiotensin I-converting enzyme
    Biochemistry (1-8-2000) 39, 8963-8969. PubMed  Europe PubMed DOI  I
    28. 1999
  28. [YEAR:23-7-1999]Ekbote,U., Coates,D. and Isaac,R.E.
    A mosquito (Anopheles stephensi) angiotensin I-converting enzyme (ACE) is induced by a blood meal and accumulates in the developing ovary
    FEBS Lett (23-7-1999) 455, 219-222. PubMed  Europe PubMed DOI
    29. 1998
  29. Houard,X., Williams,T.A., Michaud,A., Dani,P., Isaac,R.E., Shirras,A.D., Coates,D. and Corvol,P.
    The Drosophila melanogaster-related angiotensin-I-converting enzymes Acer and Ance - distinct enzymic characteristics and alternative expression during pupal development
    Eur J Biochem (1998) 257, 599-606. PubMed  Europe PubMed  I
    30. 1997
  30. Wijffels,G., Gough,J., Muharsini,S., Donaldson,A. and Eisemann,C.
    Expression of angiotensin-converting enzyme-related carboxydipeptidases in the larvae of four species of fly
    Insect Biochem Mol Biol (1997) 27, 451-460. PubMed  Europe PubMed DOI
    31. 1996
  31. [YEAR:15-4-1996]Wijffels,G., Fitzgerald,C., Gough,J., Riding,G., Elvin,C., Kemp,D. and Willadsen,P.
    Cloning and characterisation of angiotensin-converting enzyme from the dipteran species, Haematobia irritans exigua, and its expression in the maturing male reproductive system
    Eur J Biochem (15-4-1996) 237, 414-423. PubMed  Europe PubMed

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