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Literature for peptidase M02.003: peptidyl-dipeptidase Ance

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Vecchie',D., Faber,V.G., Jumbo-Lucioni,P., Anholt,R.R.H., Mackay,T.F.C. and De Luca,M.<br>Angiotensin-Converting Enzyme Inhibitors and Metabolic Aging: A Drosophila Perspective<br>Biomolecules (2025) 15 PubMed  Europe PubMed DOI  PMC  EPMC
  2. Zukowska,J., Gregory,K.S., Robinson,A., Isaac,R.E. and Acharya,K.R.<br>Molecular Basis of Dipeptide Recognition in Drosophila melanogaster Angiotensin I-Converting Enzyme Homologue, AnCE<br>Biomolecules (2025) 15 PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2023
  3. Herrera,P. and Cauchi,R.J.<br>Functional characterisation of the ACE2 orthologues in Drosophila provides insights into the neuromuscular complications of COVID-19<br>Biochim Biophys Acta Mol Basis Dis (2023) 1869, 166818-166818. PubMed  Europe PubMed DOI  K
    4. 2022
  4. Duarte,T., Silva,M.M., Michelotti,P., Barbosa,N.B.V., Feltes,B.C., Dorn,M., Rocha,J.B.T.D. and Dalla Corte,C.L.<br>The Drosophila melanogaster ACE2 ortholog genes are differently expressed in obesity/diabetes and aging models: Implications for COVID-19 pathology<br>Biochim Biophys Acta Mol Basis Dis (2022) 1868, 166551-166551. PubMed  Europe PubMed DOI  PMC  EPMC
    5. 2019
  5. Cashman,J.S., Cozier,G.E., Harrison,C., Isaac,R.E. and Acharya,K.R.<br>Crystal structures of angiotensin-converting enzyme from Anopheles gambiae in its native form and with a bound inhibitor<br>Biochem J (2019) 476, 3505-3520. PubMed  Europe PubMed DOI  S
    6. 2017
  6. Kim,A.R., Choi,E.B., Kim,M.Y. and Choi,K.W.<br>Angiotensin-converting enzyme Ance is cooperatively regulated by Mad and Pannier in Drosophila imaginal discs<br>Sci Rep (2017) 7, 13174-13174. PubMed  Europe PubMed DOI  PMC  EPMC
    7. 2015
  7. Harrison,C. and Acharya,K.R.<br>A new high-resolution crystal structure of the Drosophila melanogaster angiotensin converting enzyme homologue, AnCE<br>FEBS Open Bio (2015) 5, 661-667. PubMed  Europe PubMed DOI  PMC  EPMC  S
    8. 2014
  8. Masuyer,G., Akif,M., Czarny,B., Beau,F., Schwager,S.L., Sturrock,E.D., Isaac,R.E., Dive,V. and Acharya,K.R.<br>Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme<br>FEBS J (2014) 281, 943-956. PubMed  Europe PubMed DOI  S  I
    9. 2012
  9. Akif,M., Masuyer,G., Bingham,R.J., Sturrock,E.D., Isaac,R.E. and Acharya,K.R.<br>Structural basis of peptide recognition by the angiotensin-1 converting enzyme homologue AnCE from Drosophila melanogaster<br>FEBS J (2012) 279, 4525-4534. PubMed  Europe PubMed DOI  S
  10. Isaac,R.E. and Shirras,A.D.<br>Peptidyl-dipeptidase A (invertebrate)<br>[ISSN:978-0-12-407744-7] (2012) 3, 494-498. DOI
    11. 2011
  11. Akif,M., Masuyer,G., Schwager,S.L., Bhuyan,B.J., Mugesh,G., Isaac,R.E., Sturrock,E.D. and Acharya,K.R.<br>Structural characterization of angiotensin I-converting enzyme in complex with a selenium analogue of captopril<br>FEBS J (2011) 278, 3644-3650. PubMed  Europe PubMed DOI  S  I
    12. 2010
  12. Akif,M., Georgiadis,D., Mahajan,A., Dive,V., Sturrock,E.D., Isaac,R.E. and Acharya,K.R.<br>High-resolution crystal structures of Drosophila melanogaster angiotensin-converting enzyme in complex with novel inhibitors and antihypertensive drugs<br>J Mol Biol (2010) 400, 502-517. PubMed  Europe PubMed DOI  S  I
  13. Akif,M., Ntai,I., Sturrock,E.D., Isaac,R.E., Bachmann,B.O. and Acharya,K.R.<br>Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster<br>Biochem Biophys Res Commun (2010) 398, 532-536. PubMed  Europe PubMed DOI  S  I
    14. 2008
  14. Lemeire,E., Vanholme,B., Van Leeuwen,T., Van Camp,J. and Smagghe,G.<br>Angiotensin-converting enzyme in Spodoptera littoralis: molecular characterization, expression and activity profile during development<br>Insect Biochem Mol Biol (2008) 38, 166-175. PubMed  Europe PubMed DOI
    15. 2007
  15. Isaac,R.E., Lamango,N.S., Ekbote,U., Taylor,C.A., Hurst,D., Weaver,R.J., Carhan,A., Burnham,S. and Shirras,A.D.<br>Angiotensin-converting enzyme as a target for the development of novel insect growth regulators<br>Peptides (2007) 28, 153-162. PubMed  Europe PubMed DOI
  16. Rylett,C.M., Walker,M.J., Howell,G.J., Shirras,A.D. and Isaac,R.E.<br>Male accessory glands of Drosophila melanogaster make a secreted angiotensin I-converting enzyme (ANCE), suggesting a role for the peptide-processing enzyme in seminal fluid<br>J Exp Biol (2007) 210, 3601-3606. PubMed  Europe PubMed DOI
  17. Yan,H.Y., Iwanaga,M. and Kawasaki,H.<br>Angiotensin-converting enzyme activity in the hemolymph during last laval and pupal stages of the silkworm, Bombyx mori<br>J Insect Biotechnol Sericology (2007) 76, 17-23.
    18. 2006
  18. Bingham,R.J., Dive,V., Phillips,S.E., Shirras,A.D. and Isaac,R.E.<br>Structural diversity of angiotensin-converting enzyme - insights from structure-activity comparisons of two Drosophila enzymes<br>FEBS J (2006) 273, 362-373. PubMed  Europe PubMed DOI
    19. 2005
  19. Burnham,S., Smith,J.A., Lee,A.J., Isaac,R.E. and Shirras,A.D.<br>The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae<br>BMC Genomics (2005) 6, 172-172. PubMed  Europe PubMed DOI  PMC  EPMC
    20. 2004
  20. Isaac,R.E.<br>Peptidyl-dipeptidase A (invertebrate)<br>[ISSN:0-12-079610-4] (2004) 2, 347-349.  V
  21. Macours,N. and Hens,K.<br>Zinc-metalloproteases in insects: ACE and ECE<br>Insect Biochem Mol Biol (2004) 34, 501-510. PubMed  Europe PubMed DOI
    22. 2003
  22. [YEAR:15-2-2003]Hurst,D., Rylett,C.M., Isaac,R.E. and Shirras,A.D.<br>The Drosophila angiotensin-converting enzyme homologue Ance is required for spermiogenesis<br>Dev Biol (15-2-2003) 254, 238-247. PubMed  Europe PubMed DOI
  23. [YEAR:13-3-2003]Kim,H.M., Shin,D.R., Yoo,O.J., Lee,H. and Lee,J.O.<br>Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril<br>FEBS Lett (13-3-2003) 538, 65-70. PubMed  Europe PubMed DOI  S  I
    24. 2002
  24. Siviter,R.J., Nachman,R.J., Dani,M.P., Keen,J.N., Shirras,A.D. and Isaac,R.E.<br>Peptidyl dipeptidases (Ance and Acer) of Drosophila melanogaster: major differences in the substrate specificity of two homologs of human angiotensin I-converting enzyme<br>Peptides (2002) 23, 2025-2034. PubMed  Europe PubMed DOI
  25. [YEAR:1-10-2002]Siviter,R.J., Taylor,C.A., Cottam,D.M., Denton,A., Dani,M.P., Milner,M.J., Shirras,A.D. and Isaac,R.E.<br>Ance, a Drosophila angiotensin-converting enzyme homologue, is expressed in imaginal cells during metamorphosis and is regulated by the steroid, 20-hydroxyecdysone<br>Biochem J (1-10-2002) 367, 187-193. PubMed  Europe PubMed DOI  PMC  EPMC
    26. 2001
  26. Vandingenen,A., Hens,K., Macours,N., Zhu,W., Janssen,I., Breuer,M., De Loof,A. and Huybrechts,R.<br>Captopril, a specific inhibitor of angiotensin converting enzyme, enhances both trypsin and vitellogenin titers in the grey fleshfly Neobellieria bullata<br>Arch Insect Biochem Physiol (2001) 47, 161-167. PubMed  Europe PubMed DOI  I
    27. 2000
  27. [YEAR:1-8-2000]Coates,D., Isaac,R.E., Cotton,J., Siviter,R., Williams,T.A., Shirras,A., Corvol,P. and Dive,V.<br>Functional conservation of the active sites of human and Drosophila angiotensin I-converting enzyme<br>Biochemistry (1-8-2000) 39, 8963-8969. PubMed  Europe PubMed DOI  I
    28. 1999
  28. [YEAR:23-7-1999]Ekbote,U., Coates,D. and Isaac,R.E.<br>A mosquito (Anopheles stephensi) angiotensin I-converting enzyme (ACE) is induced by a blood meal and accumulates in the developing ovary<br>FEBS Lett (23-7-1999) 455, 219-222. PubMed  Europe PubMed DOI
    29. 1998
  29. Houard,X., Williams,T.A., Michaud,A., Dani,P., Isaac,R.E., Shirras,A.D., Coates,D. and Corvol,P.<br>The Drosophila melanogaster-related angiotensin-I-converting enzymes Acer and Ance - distinct enzymic characteristics and alternative expression during pupal development<br>Eur J Biochem (1998) 257, 599-606. PubMed  Europe PubMed  I
    30. 1997
  30. Wijffels,G., Gough,J., Muharsini,S., Donaldson,A. and Eisemann,C.<br>Expression of angiotensin-converting enzyme-related carboxydipeptidases in the larvae of four species of fly<br>Insect Biochem Mol Biol (1997) 27, 451-460. PubMed  Europe PubMed DOI
    31. 1996
  31. [YEAR:15-4-1996]Wijffels,G., Fitzgerald,C., Gough,J., Riding,G., Elvin,C., Kemp,D. and Willadsen,P.<br>Cloning and characterisation of angiotensin-converting enzyme from the dipteran species, Haematobia irritans exigua, and its expression in the maturing male reproductive system<br>Eur J Biochem (15-4-1996) 237, 414-423. PubMed  Europe PubMed

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