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Literature for peptidase M02.001: angiotensin-converting enzyme peptidase unit 1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: A Assay, S Structure, T Target, K Knockout, P Specificity, E Expression, V Review, M Mutation, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Hanak,F., Swanson,J.L., Felczak,K., Bernstein,K.E., More,S.S. and Rothwell,P.E.
    Inhibition of the angiotensin-converting enzyme N-terminal catalytic domain prevents endogenous opioid degradation in brain tissue
    bioRxiv (2025) PubMed  Europe PubMed DOI  PMC  EPMC
  2. Hanak,F., Swanson,J.L., Felczak,K., Dobariya,P., Girdwood,U.C., Bernstein,K.E., More,S.S. and Rothwell,P.E.
    Inhibition of the angiotensin-converting enzyme N-terminal catalytic domain prevents endogenous opioid degradation in brain tissue
    JCI Insight (2025) PubMed  Europe PubMed DOI
    3. 2023
  3. da Agostini,L., Cunha,W.R., Silva,N.N.T., Melo,A.S., Moreira,L.B., Almeida,T.C., Belo,V.A., Coura-Vital,W., de,M.T., Lima,A.A. and da Silva,G.N.
    Angiotensin-converting enzyme gene (ACE) polymorphisms are associated with dysregulation of biochemical parameters in hypertensive patients
    Mol Biol Rep (2023) 50, 1487-1497. PubMed  Europe PubMed DOI
    4. 2019
  4. Sturrock,E.D., Lubbe,L., Cozier,G.E., Schwager,S.L.U., Arowolo,A.T., Arendse,L.B., Belcher,E. and Acharya,K.R.
    Structural basis for the C-domain-selective angiotensin-converting enzyme inhibition by bradykinin-potentiating peptide b (BPPb)
    Biochem J (2019) 476, 1553-1570. PubMed  Europe PubMed DOI  I
    5. 2018
  5. Cozier,G.E., Arendse,L.B., Schwager,S.L., Sturrock,E.D. and Acharya,K.R.
    Molecular basis for multiple omapatrilat binding sites within the ACE C-domain: implications for drug design
    J Med Chem (2018) 61, 10141-10154. PubMed  Europe PubMed DOI  I
  6. Cozier,G.E., Schwager,S.L., Sharma,R.K., Chibale,K., Sturrock,E.D. and Acharya,K.R.
    Crystal structures of sampatrilat and sampatrilat-Asp in complex with human ACE - a molecular basis for domain selectivity
    FEBS J (2018) 285, 1477-1490. PubMed  Europe PubMed DOI  PMC  EPMC  S  I
  7. Fienberg,S., Cozier,G.E., Acharya,K.R., Chibale,K. and Sturrock,E.D.
    The design and development of a potent and selective novel diprolyl derivative that binds to the N-domain of angiotensin-I converting enzyme
    J Med Chem (2018) 61, 344-359. PubMed  Europe PubMed DOI  S  I
  8. Kugaevskaya,E.V., Veselovsky,A.V., Indeykina,M.I., Solovyeva,N.I., Zharkova,M.S., Popov,I.A., Nikolaev,E.N., Mantsyzov,A.B., Makarov,A.A. and Kozin,S.A.
    N-domain of angiotensin-converting enzyme hydrolyzes human and rat amyloid-beta(1-16) peptides as arginine specific endopeptidase potentially enhancing risk of Alzheimer's disease
    Sci Rep (2018) 8, 298-298. PubMed  Europe PubMed DOI  PMC  EPMC
    9. 2016
  9. Larmuth,K.M., Masuyer,G., Douglas,R.G., Schwager,S.L., Acharya,K.R. and Sturrock,E.D.
    Kinetic and structural characterization of amyloid-beta peptide hydrolysis by human angiotensin-1-converting enzyme
    FEBS J (2016) 283, 1060-1076. PubMed  Europe PubMed DOI  S
  10. Mu,X., Zhang,C. and Xu,D.
    QM/MM investigation of the catalytic mechanism of angiotensin-converting enzyme
    J Mol Model (2016) 22, 132-132. PubMed  Europe PubMed DOI
    11. 2015
  11. Masuyer,G., Douglas,R.G., Sturrock,E.D. and Acharya,K.R.
    Structural basis of Ac-SDKP hydrolysis by angiotensin-I converting enzyme
    Sci Rep (2015) 5, 13742-13742. PubMed  Europe PubMed DOI  PMC  EPMC  S
    12. 2014
  12. Danilov,S.M., Wade,M.S., Schwager,S.L., Douglas,R.G., Nesterovitch,A.B., Popova,I.A., Hogarth,K.D., Bhardwaj,N., Schwartz,D.E., Sturrock,E.D. and Garcia,J.G.
    A novel angiotensin I-converting enzyme mutation (S333W) impairs N-domain enzymatic cleavage of the anti-fibrotic peptide, AcSDKP
    PLoS ONE (2014) 9, e88001-e88001. PubMed  Europe PubMed DOI  PMC  EPMC  M
  13. Douglas,R.G., Sharma,R.K., Masuyer,G., Lubbe,L., Zamora,I., Acharya,K.R., Chibale,K. and Sturrock,E.D.
    Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors
    Clin Sci (Lond) (2014) 126, 305-313. PubMed  Europe PubMed DOI  I
  14. Kramer,G.J., Mohd,A., Schwager,S.L.U., Masuyer,G., Acharya,K.R., Sturrock,E.D. and Bachmann,B.O.
    Interkingdom pharmacology of angiotensin-I converting enzyme inhibitor phosphonates produced by actinomycetes
    ACS Med Chem Lett (2014) 5, 346-351. PubMed  Europe PubMed DOI  S  I
  15. Masuyer,G., Akif,M., Czarny,B., Beau,F., Schwager,S.L., Sturrock,E.D., Isaac,R.E., Dive,V. and Acharya,K.R.
    Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme
    FEBS J (2014) 281, 943-956. PubMed  Europe PubMed DOI  S  I
  16. Yates,C.J., Masuyer,G., Schwager,S.L., Akif,M., Sturrock,E.D. and Acharya,K.R.
    Molecular and thermodynamic mechanisms of the chloride-dependent human angiotensin-I-converting enzyme (ACE)
    J Biol Chem (2014) 289, 1798-1814. PubMed  Europe PubMed DOI  S
    17. 2013
  17. Hocharoen,L., Joyner,J.C. and Cowan,J.A.
    N- versus C-domain selectivity of catalytic inactivation of human angiotensin converting enzyme by lisinopril-coupled transition metal chelates
    J Med Chem (2013) 56, 9826-9836. PubMed  Europe PubMed DOI  I
    18. 2012
  18. Bersanetti,P.A., Sabatini,R.A., Matos,B.S., Douglas,R.G., Nchinda,A., Juliano,M.A., Pesquero,J.B., Sturrock,E.D. and Carmona,A.K.
    Characterization of angiotensin I-converting enzyme N-domain selectivity using positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides
    Biol Chem (2012) 393, 1547-1554. PubMed  Europe PubMed DOI  P
  19. Masuyer,G., Schwager,S.L., Sturrock,E.D., Isaac,R.E. and Acharya,K.R.
    Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides
    Sci Rep (2012) 2, 717-717. PubMed  Europe PubMed DOI  PMC  EPMC  I
  20. Ong,F.S., Lin,C.X., Campbell,D.J., Okwan-Duodu,D., Chen,X., Blackwell,W.L., Shah,K.H., Gonzalez-Villalobos,R.A., Shen,X.Z., Fuchs,S. and Bernstein,K.E.
    Increased angiotensin II-induced hypertension and inflammatory cytokines in mice lacking angiotensin-converting enzyme N domain activity
    Hypertension (2012) 59, 283-290. PubMed  Europe PubMed DOI
  21. Sharma,R.K., Douglas,R.G., Louw,S., Chibale,K. and Sturrock,E.D.
    New ketomethylene inhibitor analogues: synthesis and assessment of structural determinants for N-domain selective inhibition of angiotensin-converting enzyme
    Biol Chem (2012) 393, 485-493. PubMed  Europe PubMed DOI  I
  22. Sturrock,E.D., Anthony,C.S. and Danilov,S.M.
    Peptidyl-dipeptidase A/angiotensin I-converting enzyme
    [ISSN:978-0-12-407744-7] (2012) 3, 480-494. DOI
    23. 2011
  23. Akif,M., Schwager,S.L., Anthony,C.S., Czarny,B., Beau,F., Dive,V., Sturrock,E.D. and Acharya,K.R.
    Novel mechanism of inhibition of human angiotensin-I-converting enzyme (ACE) by a highly specific phosphinic tripeptide
    Biochem J (2011) 436, 53-59. PubMed  Europe PubMed DOI  S  I
  24. Bernstein,K.E., Shen,X.Z., Gonzalez-Villalobos,R.A., Billet,S., Okwan-Duodu,D., Ong,F.S. and Fuchs,S.
    Different in vivo functions of the two catalytic domains of angiotensin-converting enzyme (ACE)
    Curr Opin Pharmacol (2011) 11, 105-111. PubMed  Europe PubMed DOI
    25. 2010
  25. Anthony,C.S., Corradi,H.R., Schwager,S.L., Redelinghuys,P., Georgiadis,D., Dive,V., Acharya,K.R. and Sturrock,E.D.
    The N domain of human angiotensin-I-converting enzyme: the role of N-glycosylation and the crystal structure in complex with an N domain-specific phosphinic inhibitor, RXP407
    J Biol Chem (2010) 285, 35685-35693. PubMed  Europe PubMed DOI  S  I
  26. Gordon,K., Balyasnikova,I.V., Nesterovitch,A.B., Schwartz,D.E., Sturrock,E.D. and Danilov,S.M.
    Fine epitope mapping of monoclonal antibodies 9B9 and 3G8 to the N domain of angiotensin-converting enzyme (CD143) defines a region involved in regulating angiotensin-converting enzyme dimerization and shedding
    Tissue Antigens (2010) 75, 136-150. PubMed  Europe PubMed DOI
  27. Li,P., Xiao,H.D., Xu,J., Ong,F.S., Kwon,M., Roman,J., Gal,A., Bernstein,K.E. and Fuchs,S.
    Angiotensin-converting enzyme N-terminal inactivation alleviates bleomycin-induced lung injury
    Am J Pathol (2010) 177, 1113-1121. PubMed  Europe PubMed DOI  K  I
  28. Spyranti,Z., Galanis,A.S., Pairas,G., Spyroulias,G.A., Manessi-Zoupa,E. and Cordopatis,P.
    Synthetic peptides as structural maquettes of angiotensin-I converting enzyme catalytic sites
    Bioinorg Chem Appl (2010) , 820476-820476. PubMed  Europe PubMed DOI  PMC  EPMC
  29. Sun,X., Rentzsch,B., Gong,M., Eichhorst,J., Pankow,K., Papsdorf,G., Maul,B., Bader,M. and Siems,W.E.
    Signal transduction in CHO cells stably transfected with domain-selective forms of murine ACE
    Biol Chem (2010) 391, 235-244. PubMed  Europe PubMed DOI
  30. Watermeyer,J., Kroger,W.L., Sturrock,E.D. and Ehlers,M.R.
    Angiotensin-converting enzyme - new insights into structure, biological significance and prospects for domain-selective inhibitors
    Curr Enzyme Inhib (2010) 5, 134-147.
    31. 2009
  31. Kroger,W.L., Douglas,R.G., O'Neill,H.G., Dive,V. and Sturrock,E.D.
    Investigating the domain specificity of phosphinic inhibitors RXPA380 and RXP407 in angiotensin-converting enzyme
    Biochemistry (2009) 48, 8405-8412. PubMed  Europe PubMed DOI  I
  32. Zou,K., Maeda,T., Watanabe,A., Liu,J., Liu,S., Oba,R., Satoh,Y., Komano,H. and Michikawa,M.
    Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme
    J Biol Chem (2009) 284, 31914-31920. PubMed  Europe PubMed DOI  PMC  EPMC
    33. 2008
  33. Danilov,S.M., Balyasnikova,I.V., Albrecht,R.F. and Kost,O.A.
    Simultaneous determination of ACE activity with 2 substrates provides information on the status of somatic ACE and allows detection of inhibitors in human blood
    J Cardiovasc Pharmacol (2008) 52, 90-103. PubMed  Europe PubMed DOI  A
  34. O'Neill,H.G., Redelinghuys,P., Schwager,S.L. and Sturrock,E.D.
    The role of glycosylation and domain interactions in the thermal stability of human angiotensin-converting enzyme
    Biol Chem (2008) 389, 1153-1161. PubMed  Europe PubMed DOI
  35. Rushworth,C.A., Guy,J.L. and Turner,A.J.
    Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis
    FEBS J (2008) 275, 6033-6042. PubMed  Europe PubMed DOI  I
  36. Toropygin,I.Y., Kugaevskaya,E.V., Mirgorodskaya,O.A., Elisseeva,Y.E., Kozmin,Y.P., Popov,I.A., Nikolaev,E.N., Makarov,A.A. and Kozin,S.A.
    The N-domain of angiotensin-converting enzyme specifically hydrolyzes the Arg-5-His-6 bond of Alzheimer's Abeta-(1-16) peptide and its isoAsp-7 analogue with different efficiency as evidenced by quantitative matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
    Rapid Commun Mass Spectrom (2008) 22, 231-239. PubMed  Europe PubMed DOI
  37. Watermeyer,J.M., Kroger,W.L., O'Neill,H.G., Sewell,B.T. and Sturrock,E.D.
    Probing the basis of domain-dependent inhibition using novel ketone inhibitors of angiotensin-converting enzyme
    Biochemistry (2008) 47, 5942-5950. PubMed  Europe PubMed DOI  I
    38. 2007
  38. Balyasnikova,I.V., Skirgello,O.E., Binevski,P.V., Nesterovitch,A.B., Albrecht,R.F., Kost,O.A. and Danilov,S.M.
    Monoclonal antibodies 1G12 and 6A12 to the N-domain of human angiotensin-converting enzyme: fine epitope mapping and antibody-based detection of ACE inhibitors in human blood
    J Proteome Res (2007) 6, 1580-1594. PubMed  Europe PubMed DOI
  39. Danilov,S.M., Watermeyer,J.M., Balyasnikova,I.V., Gordon,K., Kugaevskaya,E.V., Elisseeva,Y.E., Albrecht,R.F. and Sturrock,E.D.
    Fine epitope mapping of monoclonal antibody 5F1 reveals anticatalytic activity toward the N domain of human angiotensin-converting enzyme
    Biochemistry (2007) 46, 9019-9031. PubMed  Europe PubMed DOI
  40. Vamvakas,S.S., Leondiadis,L., Pairas,G., Manessi-Zoupa,E., Spyroulias,G.A. and Cordopatis,P.
    Expression, purification, and physicochemical characterization of the N-terminal active site of human angiotensin-I converting enzyme
    J Pept Sci (2007) 13, 31-36. PubMed  Europe PubMed DOI  E
    41. 2006
  41. [YEAR:19-12-2006]Bernstein,K.E.
    Views of the renin-angiotensin system: brilling, mimsy, and slithy tove
    Hypertension (19-12-2006) 47, 509-514. PubMed  Europe PubMed DOI  V
  42. Carmona,A.K., Schwager,S.L., Juliano,M.A., Juliano,L. and Sturrock,E.D.
    A continuous fluorescence resonance energy transfer angiotensin I-converting enzyme assay
    Nat Protoc (2006) 1, 1971-1976. PubMed  Europe PubMed DOI  A
  43. Corradi,H.R., Schwager,S.L., Nchinda,A.T., Sturrock,E.D. and Acharya,K.R.
    Crystal structure of the N domain of human somatic angiotensin I-converting enzyme provides a structural basis for domain-specific inhibitor design
    J Mol Biol (2006) 357, 964-974. PubMed  Europe PubMed DOI  S  T  I
  44. Kohlstedt,K., Gershome,C., Friedrich,M., Muller-Esterl,W., Alhenc-Gelas,F., Busse,R. and Fleming,I.
    Angiotensin-converting enzyme (ACE) dimerization is the initial step in the ACE inhibitor-induced ACE signaling cascade in endothelial cells
    Mol Pharmacol (2006) 69, 1725-1732. PubMed  Europe PubMed DOI
  45. [YEAR:13-3-2006]Kugaevskaya,E.V., Kolesanova,E.F., Kozin,S.A., Veselovsky,A.V., Dedinsky,I.R. and Elisseeva,Y.E.
    Epitope mapping of the domains of human angiotensin converting enzyme
    Biochim Biophys Acta (13-3-2006) 1760, 959-965. PubMed  Europe PubMed DOI
  46. [YEAR:18-4-2006]Skirgello,O.E., Balyasnikova,I.V., Binevski,P.V., Sun,Z.L., Baskin,I.I., Palyulin,V.A., Nesterovitch,A.B., Albrecht,R.F., Kost,O.A. and Danilov,S.M.
    Inhibitory antibodies to human angiotensin-converting enzyme: fine epitope mapping and mechanism of action
    Biochemistry (18-4-2006) 45, 4831-4847. PubMed  Europe PubMed DOI
    47. 2005
  47. Alves,M.F., Araujo,M.C., Juliano,M.A., Oliveira,E.M., Krieger,J.E., Casarini,D.E., Juliano,L. and Carmona,A.K.
    A continuous fluorescent assay for the determination of plasma and tissue angiotensin I-converting enzyme activity
    Braz J Med Biol Res (2005) 38, 861-868. PubMed  Europe PubMed DOI  A
  48. Balyasnikova,I.V., Woodman,Z.L., Albrecht,R.F., Natesh,R., Acharya,K.R., Sturrock,E.D. and Danilov,S.M.
    Localization of an N-domain region of angiotensin-converting enzyme involved in the regulation of ectodomain shedding using monoclonal antibodies
    J Proteome Res (2005) 4, 258-267. PubMed  Europe PubMed DOI
  49. Redelinghuys,P., Nchinda,A.T. and Sturrock,E.D.
    Development of domain-selective angiotensin I-converting enzyme inhibitors
    Ann N Y Acad Sci (2005) 1056, 160-175. PubMed  Europe PubMed DOI  V
  50. [YEAR:1-8-2005]Woodman,Z.L., Schwager,S.L., Redelinghuys,P., Carmona,A.K., Ehlers,M.R. and Sturrock,E.D.
    The N domain of somatic angiotensin-converting enzyme negatively regulates ectodomain shedding and catalytic activity
    Biochem J (1-8-2005) 389, 739-744. PubMed  Europe PubMed DOI  PMC  EPMC
    51. 2004
  51. Corvol,P., Eyries,M. and Soubrier,F.
    Peptidyl-dipeptidase A/angiotensin I-converting enzyme
    [ISSN:0-12-079610-4] (2004) 2, 332-346.  V
  52. [YEAR:16-4-2004]Fuchs,S., Xiao,H.D., Cole,J.M., Adams,J.W., Frenzel,K., Michaud,A., Zhao,H., Keshelava,G., Capecchi,M.R., Corvol,P. and Bernstein,K.E.
    Role of the N-terminal catalytic domain of angiotensin-converting enzyme investigated by targeted inactivation in mice
    J Biol Chem (16-4-2004) 279, 15946-15953. PubMed  Europe PubMed DOI
  53. Inguimbert,N., Poras,H., Dhotel,H., Beslot,F., Scalbert,E., Bennejean,C., Renard,P., Fournie-Zaluski,M.C. and Roques,B.P.
    In vivo properties of thiol inhibitors of the three vasopeptidases NEP, ACE and ECE are improved by introduction of a 7-azatryptophan in P2' position
    J Pept Res (2004) 63, 99-107. PubMed  Europe PubMed DOI  I
  54. Spyroulias,G.A., Galanis,A.S., Pairas,G., Manessi-Zoupa,E. and Cordopatis,P.
    Structural features of angiotensin-I converting enzyme catalytic sites: conformational studies in solution, homology models and comparison with other zinc metallopeptidases
    Curr Top Med Chem (2004) 4, 403-429. PubMed  Europe PubMed DOI
  55. Sturrock,E.D., Natesh,R., van Rooyen,J.M. and Acharya,K.R.
    Structure of angiotensin I-converting enzyme
    Cell Mol Life Sci (2004) 61, 2677-2686. PubMed  Europe PubMed DOI  V  S  I
    56. 2003
  56. [YEAR:28-8-2003]Binevski,P.V., Sizova,E.A., Pozdnev,V.F. and Kost,O.A.
    Evidence for the negative cooperativity of the two active sites within bovine somatic angiotensin-converting enzyme
    FEBS Lett (28-8-2003) 550, 84-88. PubMed  Europe PubMed DOI  I
  57. [YEAR:22-8-2003]Fernandez,J.H., Hayashi,M.A., Camargo,A.C. and Neshich,G.
    Structural basis of the lisinopril-binding specificity in N- and C-domains of human somatic ACE
    Biochem Biophys Res Commun (22-8-2003) 308, 219-226. PubMed  Europe PubMed DOI
  58. Marques,G.D., Quinto,B.M., Plavinik,F.L., Krieger,J.E., Marson,O. and Casarini,D.E.
    N-domain angiotensin I-converting enzyme with 80 kDa as a possible genetic marker of hypertension
    Hypertension (2003) 42, 693-701. PubMed  Europe PubMed DOI
  59. Tzakos,A.G., Galanis,A.S., Spyroulias,G.A., Cordopatis,P., Manessi-Zoupa,E. and Gerothanassis,I.P.
    Structure-function discrimination of the N- and C- catalytic domains of human angiotensin-converting enzyme: implications for Cl- activation and peptide hydrolysis mechanisms
    Protein Eng (2003) 16, 993-1003. PubMed  Europe PubMed DOI
    60. 2002
  60. Voronov,S., Zueva,N., Orlov,V., Arutyunyan,A. and Kost,O.
    Temperature-induced selective death of the C-domain within angiotensin-converting enzyme molecule
    FEBS Lett (2002) 522, 77-82. PubMed  Europe PubMed DOI
    61. 2001
  61. Junot,C., Gonzales,M.F., Ezan,E., Cotton,J., Vazeux,G., Michaud,A., Azizi,M., Vassiliou,S., Yiotakis,A., Corvol,P. and Dive,V.
    RXP 407, a selective inhibitor of the N-domain of angiotensin I-converting enzyme, blocks in vivo the degradation of hemoregulatory peptide acetyl-Ser-Asp-Lys-Pro with no effect on angiotensin I hydrolysis
    J Pharmacol Exp Ther (2001) 297, 606-611. PubMed  Europe PubMed  I
  62. Menard,J. and Patchett,A.A.
    Angiotensin-converting enzyme inhibitors
    Adv Protein Chem (2001) 56, 13-75. PubMed  Europe PubMed DOI  V  I
  63. [YEAR:1-4-2001]Vazeux,G., Cotton,J., Cuniasse,P. and Dive,V.
    Potency and selectivity of RXP407 on human, rat, and mouse angiotensin-converting enzyme
    Biochem Pharmacol (1-4-2001) 61, 835-841. PubMed  Europe PubMed DOI  I
    64. 2000
  64. [YEAR:25-7-2000]Araujo,M.C., Melo,R.L., Cesari,M.H., Juliano,M.A., Juliano,L. and Carmona,A.K.
    Peptidase specificity characterization of C- and N-terminal catalytic sites of angiotensin I-converting enzyme
    Biochemistry (25-7-2000) 39, 8519-8525. PubMed  Europe PubMed DOI
  65. Azizi,M., Massien,C., Michaud,A. and Corvol,P.
    In vitro and in vivo inhibition of the 2 active sites of ACE by omapatrilat, a vasopeptidase inhibitor
    Hypertension (2000) 35, 1226-1231. PubMed  Europe PubMed  I
  66. Binevski,P.V., Nikolskaya,I.I., Pozdnev,V.F. and Kost,O.A.
    Isolation and characterization of the N-domain of bovine angiotensin-converting enzyme
    Biochemistry (Mosc) (2000) 65, 651-658. PubMed  Europe PubMed
  67. [YEAR:10-4-2000]Cheviron,N., Rousseau-Plasse,A., Lenfant,M., Adeline,M.T., Potier,P. and Thierry,J.
    Coumarin-Ser-Asp-Lys-Pro-OH, a fluorescent substrate for determination of angiotensin-converting enzyme activity via high-performance liquid chromatography
    Anal Biochem (10-4-2000) 280, 58-64. PubMed  Europe PubMed DOI  A
  68. [YEAR:1-8-2000]Coates,D., Isaac,R.E., Cotton,J., Siviter,R., Williams,T.A., Shirras,A., Corvol,P. and Dive,V.
    Functional conservation of the active sites of human and Drosophila angiotensin I-converting enzyme
    Biochemistry (1-8-2000) 39, 8963-8969. PubMed  Europe PubMed DOI  I
  69. [YEAR:25-8-2000]Kessler,S.P., Rowe,T.M., Gomos,J.B., Kessler,P.M. and Sen,G.C.
    Physiological non-equivalence of the two isoforms of angiotensin-converting enzyme
    J Biol Chem (25-8-2000) 275, 26259-26264. PubMed  Europe PubMed DOI
  70. Ortiz-Salmeron,E., Baron,C. and Garcia-Fuentes,L.
    Separation and purification of N-domain of bovine lung angiotensin I-converting enzyme by size exclusion chromatography
    J Liq Chromatogr Relat Technol (2000) 23, 1499-1510. DOI
    71. 1999
  71. Araujo,M.C., Melo,R.I., Del Nery,E., Alves,M.F., Juliano,M.A., Casarini,D.E., Juliano,L. and Carmona,A.K.
    Internally quenched fluorogenic substrates for angiotensin I-converting enzyme
    J Hypertens (1999) 17, 665-672. PubMed  Europe PubMed DOI  A
  72. [YEAR:13-4-1999]Dive,V., Cotton,J., Yiotakis,A., Michaud,A., Vassiliou,S., Jiracek,J., Vazeux,G., Chauvet,M.T., Cuniasse,P. and Corvol,P.
    RXP 407, a phosphinic peptide, is a potent inhibitor of angiotensin I converting enzyme able to differentiate between its two active sites
    Proc Natl Acad Sci U S A (13-4-1999) 96, 4330-4335. PubMed  Europe PubMed DOI  PMC  EPMC  I
  73. Junot,C., Menard,J., Gonzales,M.F., Michaud,A., Corvol,P. and Ezan,E.
    In vivo assessment of captopril selectivity of angiotensin I-converting enzyme inhibition: differential inhibition of acetyl-Ser-Asp-Lys-Pro and angiotensin I hydrolysis
    J Pharmacol Exp Ther (1999) 289, 1257-1261. PubMed  Europe PubMed  I
  74. [YEAR:15-3-1999]Michaud,A., Chauvet,M.T. and Corvol,P.
    N-domain selectivity of angiotensin I-converting enzyme as assessed by structure-function studies of its highly selective substrate, N-acetyl-seryl-aspartyl-lysyl-proline
    Biochem Pharmacol (15-3-1999) 57, 611-618. PubMed  Europe PubMed DOI
    75. 1998
  75. Deddish,P.A., Marcic,B., Jackman,H.L., Wang,H.Z., Skidgel,R.A. and Erdos,E.G.
    N-domain-specific substrate and C-domain inhibitors of angiotensin-converting enzyme: angiotensin-(1-7) and keto-ACE
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