Literature for peptidase C65.001: otubain-1

(Topics flags: S Structure, P Specificity, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Ai,S., Pan,J., Liu,Q., Tang,F., Wen,T., Yuan,Y., He,Q. and Huang,L.
   OTUB1 mediates PARP1 deubiquitination to alleviate NAFLD by regulating HMGB1
   Exp Cell Res445, 114425-114425. PubMed  Europe PubMed DOI
2024
2. Li,S., Yang,M., Zhao,Y., Zhai,Y., Sun,C., Guo,Y., Zhang,X., Zhang,L., Tian,T., Yang,Y., Pei,Y., Li,J., Li,C., Xuan,L., Li,X., Zhao,D., Yang,H., Zhang,Y., Yang,B., Zhang,Z., Pan,Z. and Lu,Y.
   Deletion of ASPP1 in myofibroblasts alleviates myocardial fibrosis by reducing p53 degradation
   Nat Commun15, 8425-8425. PubMed  Europe PubMed DOI
3. Liao,Y., Liang,J., Wang,Y., Li,A., Liu,W., Zhong,B., Wang,K., Zhou,D., Guo,T., Guo,J., Yu,X. and Jiang,N.
   Target deubiquitinase OTUB1 as a therapeatic strategy for BLCA via beta-catenin/necroptosis signal pathway
   Int J Biol Sci20, 3784-3801. PubMed  Europe PubMed DOI
4. Majumder,S., Srivastava,M., Alam,P., Saha,S., Kumari,R., Chand,A.K., Asthana,S., Sen,S. and Maiti,T.K.
   Hotspot site microenvironment in the deubiquitinase OTUB1 drives its stability and aggregation
   J Biol Chem107315-107315. PubMed  Europe PubMed DOI
5. Xu,F., Zang,T., Chen,H., Zhou,C., Wang,R., Yu,Y., Shen,L., Qian,J. and Ge,J.
   Deubiquitinase OTUB1 regulates doxorubicin-induced cardiotoxicity via deubiquitinating c-MYC
   Cell Signal113, 110937-110937. PubMed  Europe PubMed DOI  K
6. Xue,Y., Xue,C. and Song,W.
   Emerging roles of deubiquitinating enzymes in actin cytoskeleton and tumor metastasis
   Cell Oncol (Dordr) PubMed  Europe PubMed DOI  V
7. Yang,J., Zhang,N., He,Z., Xiong,J., Meng,W., Xue,C., Ying,L., Li,M., Liu,M. and Ouyang,T.
   OTUB1 Promotes Glioblastoma Growth by Inhibiting the JAK2/STAT1 Signaling Pathway
   J Cancer15, 4566-4576. PubMed  Europe PubMed DOI  K
8. Zhao,Q., Wang,Q., Li,B., Han,S., Zhang,Y., Wang,Y., Lu,R., Chen,Q., Sun,Z., Ding,M., Liang,Z. and Gao,Y.
   The deubiquitinase OTUB1 inhibits gluconeogenesis by stabilizing YWHAB
   Cell Signal124, 111408-111408. PubMed  Europe PubMed DOI
9. Zhao,X., Lv,S., Li,N., Zou,Q., Sun,L. and Song,T.
   YTHDF2 protein stabilization by the deubiquitinase OTUB1 promotes prostate cancer cell proliferation via PRSS8 mRNA degradation
   J Biol Chem300, 107152-107152. PubMed  Europe PubMed DOI
2023
10. Aboushousha,R., van der Velden,J., Hamilton,N., Peng,Z., MacPherson,M., Erickson,C., White,S., Wouters,E.F.M., Reynaert,N.L., Seward,D.J., Li,J. and Janssen-Heininger,Y.M.W.
    Glutaredoxin attenuates glutathione levels via deglutathionylation of Otub1 and subsequent destabilization of system x(C)()
    Sci Adv9, eadi5192-eadi5192. PubMed  Europe PubMed DOI
11. Galindo-Hernandez,O., Garcia-Salazar,L.A., Garcia-Gonzalez,V.G., Diaz-Molina,R. and Vique-Sanchez,J.L.
    Potential Inhibitors of The OTUB1 Catalytic Site to Develop an Anti-Cancer Drug Using In-Silico Approaches
    Rep Biochem Mol Biol11, 684-693. PubMed  Europe PubMed DOI
12. Jin,S., Tsunematsu,T., Horiguchi,T., Mouri,Y., Shao,W., Miyoshi,K., Hagita,H., Sarubo,M., Fujiwara,N., Qi,G., Ishimaru,N. and Kudo,Y.
    Involvement of the OTUB1-YAP1 axis in driving malignant behaviors of head and neck squamous cell carcinoma
    Cancer Med12, 22156-22169. PubMed  Europe PubMed DOI
13. Li,D., Wang,Y., Dong,C., Chen,T., Dong,A., Ren,J., Li,W., Shu,G., Yang,J., Shen,W., Qin,L., Hu,L. and Zhou,J.
    CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1
    Oncogene42, 83-98. PubMed  Europe PubMed DOI
14. Li,M., Wang,X., Yang,E., Li,Y., Geng,Y., Chen,Z., Huang,S., Zhang,D. and Wu,H.
    OTUB1 Catalytic-Independently Deubiquitinates TGFBI and Mediates the Angiogenesis in Infantile Hemangioma by Regulating Glycolysis
    Arterioscler Thromb Vasc Biol43, 654-673. PubMed  Europe PubMed DOI  K
15. Li,Y., Li,R., Qin,H., He,H. and Li,S.
    OTUB1's role in promoting OSCC development by stabilizing RACK1 involves cell proliferation, migration, invasion, and tumor-associated macrophage M1 polarization
    Cell Signal110, 110835-110835. PubMed  Europe PubMed DOI  K
16. Liu,N., Lin,M.M. and Wang,Y.
    The Emerging Roles of E3 Ligases and DUBs in Neurodegenerative Diseases
    Mol Neurobiol60, 247-263. PubMed  Europe PubMed DOI  V
17. Seo,S.U., Woo,S.M. and Kwon,T.K.
    Cathepsin K inhibition induces Raptor destabilization and mitochondrial dysfunction via Syk/SHP2/Src/OTUB1 axis-mediated signaling
    Cell Death Dis14, 366-366. PubMed  Europe PubMed DOI  K
18. Shang,L., Du,Y., Zhao,Y., Zhang,Y. and Liu,C.
    The Interaction of OTUB1 and TRAF3 Mediates NLRP3 Inflammasome Activity to Regulate TGF-beta1-induced BEAS-2B Cell Injury
    Appl Biochem Biotechnol195, 7060-7074. PubMed  Europe PubMed DOI  K
19. Sheryazdanova,A., Amoedo,N.D., Dufour,S., Impens,F., Rossignol,R. and Sablina,A.
    The deubiquitinase OTUB1 governs lung cancer cell fitness by modulating proteostasis of OXPHOS proteins
    Biochim Biophys Acta Mol Basis Dis1869, 166767-166767. PubMed  Europe PubMed DOI
20. Sorada,T., Morimoto,D., Walinda,E. and Sugase,K.
    Corrigendum to "Molecular recognition and deubiquitination of cyclic K48-linked ubiquitin chains by OTUB1" [Biochem. Biophys. Res. Commun. 562 (2021) 94-99]
    Biochem Biophys Res Commun660, 100-100. PubMed  Europe PubMed DOI
21. Xing,X., Xu,F., Wang,Y. and Liu,H.
    Role of the OTUB1/IRF7/NOX4 axis in oxidative stress injury and inflammatory responses in mice with Parkinson's disease
    Psychogeriatrics23, 32-44. PubMed  Europe PubMed DOI
22. Zhang,W., Qian,W., Gu,J., Gong,M., Zhang,W., Zhang,S., Zhou,C., Jiang,Z., Jiang,J., Han,L., Wang,X., Wu,Z., Ma,Q. and Wang,Z.
    Mutant p53 driven-LINC00857, a protein scaffold between FOXM1 and deubiquitinase OTUB1, promotes the metastasis of pancreatic cancer
    Cancer Lett552, 215976-215976. PubMed  Europe PubMed DOI
23. Zhao,Y., Ruan,J., Li,Z., Su,X., Chen,K., Lin,Y., Cai,Y., Wang,P., Liu,B., Schluter,D., Liang,G. and Wang,X.
    OTUB1 inhibits breast cancer by non-canonically stabilizing CCN6
    Clin Transl Med13, e1385-e1385. PubMed  Europe PubMed DOI
24. Zhu,Q., Fu,Y., Cui,C.P., Ding,Y., Deng,Z., Ning,C., Hu,F., Qiu,C., Yu,B., Zhou,X., Yang,G., Peng,J., Zou,W., Liu,C.H. and Zhang,L.
    OTUB1 promotes osteoblastic bone formation through stabilizing FGFR2
    Signal Transduct Target Ther8, 142-142. PubMed  Europe PubMed DOI
2022
25. Han,X., Ren,C., Lu,C., Qiao,P., Yang,T. and Yu,Z.
    Deubiquitination of MYC by OTUB1 contributes to HK2 mediated glycolysis and breast tumorigenesis
    Cell Death Differ29, 1864-1873. PubMed  Europe PubMed DOI
26. Henning,N.J., Boike,L., Spradlin,J.N., Ward,C.C., Liu,G., Zhang,E., Belcher,B.P., Brittain,S.M., Hesse,M.J., Dovala,D., McGregor,L.M., Valdez Misiolek,R., Plasschaert,L.W., Rowlands,D.J., Wang,F., Frank,A.O., Fuller,D., Estes,A.R., Randal,K.L., Panidapu,A., McKenna,J.M., Tallarico,J.A., Schirle,M. and Nomura,D.K.
    Deubiquitinase-targeting chimeras for targeted protein stabilization
    Nat Chem Biol18, 412-421. PubMed  Europe PubMed DOI
27. Kumari,R., Kumar,R., Dey,A.K., Saha,S. and Maiti,T.K.
    S-Nitrosylation of OTUB1 Alters Its Stability and Ubc13 Binding
    ACS Chem Neurosci13, 1517-1525. PubMed  Europe PubMed DOI
28. Lin,F., Chen,W., Zhou,J., Zhu,J., Yao,Q., Feng,B., Feng,X., Shi,X., Pan,Q., Yu,J., Li,L. and Cao,H.
    Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury
    Cell Death Dis13, 271-271. PubMed  Europe PubMed DOI
29. Ling,X., Lu,J., Wang,X., Liu,L., Liu,L., Wang,Y., Sun,Y., Ren,C., Lu,C. and Yu,Z.
    Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis
    iScience25, 105363-105363. PubMed  Europe PubMed DOI
30. Liu,J., Yu,X., Chen,H., Kaniskan,H.U., Xie,L., Chen,X., Jin,J. and Wei,W.
    TF-DUBTACs Stabilize Tumor Suppressor Transcription Factors
    J Am Chem Soc144, 12934-12941. PubMed  Europe PubMed DOI
31. Stutz,A., Nishanth,G., Zenclussen,A.C. and Schumacher,A.
    Partial otubain 1 deficiency compromises fetal well-being in allogeneic pregnancies despite no major changes in the dendritic cell and T cell compartment
    BMC Res Notes15, 341-341. PubMed  Europe PubMed DOI
32. Tan,L., Shan,H., Han,C., Zhang,Z., Shen,J., Zhang,X., Xiang,H., Lu,K., Qi,C., Li,Y., Zhuang,G., Chen,G. and Tan,L.
    Discovery of Potent OTUB1/USP8 Dual Inhibitors Targeting Proteostasis in Non-Small-Cell Lung Cancer
    J Med Chem65, 13645-13659. PubMed  Europe PubMed DOI  K  I
33. Wang,S., Wang,Y., Li,Q., Li,X. and Feng,X.
    A novel circular RNA confers trastuzumab resistance in human epidermal growth factor receptor 2-positive breast cancer through regulating ferroptosis
    Environ Toxicol PubMed  Europe PubMed DOI  K
34. Yan,C., Yang,H., Su,P., Li,X., Li,Z., Wang,D., Zang,Y., Wang,T., Liu,Z., Bao,Z., Dong,S., Zhuang,T., Zhu,J. and Ding,Y.
    OTUB1 suppresses Hippo signaling via modulating YAP protein in gastric cancer
    Oncogene41, 5186-5198. PubMed  Europe PubMed DOI  K
35. Ye,D., Wang,S., Wang,X., Lin,Y., Huang,Y. and Chi,P.
    Overexpression of OTU domain-containing ubiquitin aldehyde-binding protein 1 exacerbates colorectal cancer malignancy by inhibiting protein degradation of beta-Catenin via Ubiquitin-proteasome pathway
    Bioengineered13, 9106-9116. PubMed  Europe PubMed DOI
36. Zhang,J.L., Du,B.B., Zhang,D.H., Li,H., Kong,L.Y., Fan,G.J., Li,Y.P., Li,P.C., Liang,C., Wang,Z., Yang,L.L., Hao,Z.Y., Wu,L.M., Huang,Z., Dong,J.Z., Zhang,J.Y., Yao,R., Wang,S.J. and Zhang,Y.Z.
    OTUB1 Alleviates Nonalcoholic Steatosis through Inhibition of the TRAF6-ASK1 Signaling Pathways
    Hepatology75, 1218-1234. PubMed  Europe PubMed DOI
37. Zhong,X., Wang,T., Zhang,W., Wang,M., Xie,Y., Dai,L., He,X., Madhusudhan,T., Zeng,H. and Wang,H.
    ERK/RSK-mediated phosphorylation of Y-box binding protein-1 aggravates diabetic cardiomyopathy by suppressing its interaction with deubiquitinase OTUB1
    J Biol Chem298, 101989-101989. PubMed  Europe PubMed DOI
2021
38. Jiang,D.J., Hao,X.H., Zhang,J., Tang,H. and Wang,F.
    Reducing expression of TaOTUB1s decreases tiller number in wheat
    Plant Signal Behav16, 2018217-2018217. PubMed  Europe PubMed DOI
39. Kim,S., Park,K., Oh,J.M. and Kim,H.
    RNF126 is a positive regulator of TRAF3 ubiquitination
    Biosci Biotechnol Biochem PubMed  Europe PubMed DOI
40. Koschel,J., Nishanth,G., Just,S., Harit,K., Kroger,A., Deckert,M., Naumann,M. and Schluter,D.
    OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation
    Cell Death Differ PubMed  Europe PubMed DOI
41. Lee,B.S., Kang,S.U., Huang,M., Kim,Y.S., Lee,Y.S., Park,J.Y. and Kim,C.H.
    OTUB1 knockdown promotes apoptosis in melanoma cells by upregulating TRAIL expression
    BMB Rep PubMed  Europe PubMed
42. Liu,Z., Wang,T., She,Y., Wu,K., Gu,S., Li,L., Dong,C., Chen,C. and Zhou,Y.
    N(6)-methyladenosine-modified circIGF2BP3 inhibits CD8(+) T-cell responses to facilitate tumor immune evasion by promoting the deubiquitination of PD-L1 in non-small cell lung cancer
    Mol Cancer20, 105-105. PubMed  Europe PubMed DOI
43. Sivakumar,D. and Stein,M.
    Binding of SARS-CoV Covalent Non-Covalent Inhibitors to the SARS-CoV-2 Papain-Like Protease and Ovarian Tumor Domain Deubiquitinases
    Biomolecules11, PubMed  Europe PubMed DOI
44. Sorada,T., Morimoto,D., Walinda,E. and Sugase,K.
    Molecular recognition and deubiquitination of cyclic K48-linked ubiquitin chains by OTUB1
    Biochem Biophys Res Commun562, 94-99. PubMed  Europe PubMed DOI
45. Sun,T., Xu,Y., Xu,Z., Cao,B., Zhang,Z., Wang,Q., Kong,Y. and Mao,X.
    Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis
    Cell Commun Signal19, 24-24. PubMed  Europe PubMed DOI
46. Weber,E., Schorpp,K. and Hadian,K.
    Studying OTUD6B-OTUB1 Protein-Protein Interaction by Low-Throughput GFP-Trap Assays and High-Throughput AlphaScreen Assays
    Methods Mol Biol2261, 381-394. PubMed  Europe PubMed DOI
47. Wu,Q., Huang,Y., Gu,L., Chang,Z. and Li,G.M.
    OTUB1 stabilizes mismatch repair protein MSH2 by blocking ubiquitination
    J Biol Chem100466-100466. PubMed  Europe PubMed DOI
48. Xu,Y., Xu,M., Tong,J., Tang,X., Chen,J., Chen,X., Zhang,Z., Cao,B., Stewart,A.K., Moran,M.F., Wu,D. and Mao,X.
    Targeting the Otub1/c-Maf axis for the treatment of multiple myeloma
    Blood137, 1478-1490. PubMed  Europe PubMed DOI
49. Zhang,H.H., Li,C., Ren,J.W., Liu,L., Du,X.H., Gao,J., Liu,T. and Li,S.Z.
    OTUB1 facilitates bladder cancer progression by stabilizing ATF6 in response to ER stress
    Cancer Sci112, 2199-2209. PubMed  Europe PubMed DOI
50. Zhang,Y., Zhu,Y., Xiao,M., Cheng,Y., He,D., Liu,J., Xiang,L., Gong,L., Wang,Z., Deng,L. and Cao,K.
    The Long Non-coding RNA TMPO-AS1 Promotes Bladder Cancer Growth and Progression via OTUB1-Induced E2F1 Deubiquitination
    Front Oncol11, 643163-643163. PubMed  Europe PubMed DOI  K
51. Zhao,X., Zhou,M., Yang,Y. and Luo,M.
    The ubiquitin hydrolase OTUB1 promotes glioma cell stemness via suppressing ferroptosis through stabilizing SLC7A11 protein
    Bioengineered12, 12636-12645. PubMed  Europe PubMed DOI  K
52. Zhu,D., Xu,R., Huang,X., Tang,Z., Tian,Y., Zhang,J. and Zheng,X.
    Deubiquitinating enzyme OTUB1 promotes cancer cell immunosuppression via preventing ER-associated degradation of immune checkpoint protein PD-L1
    Cell Death Differ28, 1773-1789. PubMed  Europe PubMed DOI
53. Zhu,Q., Fu,Y., Li,L., Liu,C.H. and Zhang,L.
    The functions and regulation of Otubains in protein homeostasis and diseases
    Ageing Res Rev67, 101303-101303. PubMed  Europe PubMed DOI  V
2020
54. Kumari,R., Kumar,R., Kumar,S., Singh,A.K., Hanpude,P., Jangir,D. and Maiti,T.K.
    Amyloid aggregates of the deubiquitinase OTUB1 are neurotoxic, suggesting that they contribute to the development of Parkinson's disease
    J Biol Chem295, 3466-3484. PubMed  Europe PubMed DOI
55. Liao,Y., Wu,N., Wang,K., Wang,M., Wang,Y., Gao,J., Zhong,B., Ma,F., Wu,Y. and Jiang,N.
    OTUB1 Promotes Progression and Proliferation of Prostate Cancer via Deubiquitinating and Stabling Cyclin E1
    Front Cell Dev Biol8, 617758-617758. PubMed  Europe PubMed DOI
56. Sivakumar,D., Kumar,V., Naumann,M. and Stein,M.
    Activation and selectivity of OTUB-1 and OTUB-2 deubiquitinylases
    J Biol Chem295, 6972-6982. PubMed  Europe PubMed DOI
57. Zhang,W. and Qiu,W.
    OTUB1 Recruits Tumor Infiltrating Lymphocytes and Is a Prognostic Marker in Digestive Cancers
    Front Mol Biosci7, 212-212. PubMed  Europe PubMed DOI
58. Zhou,K., Mai,H., Zheng,S., Cai,W., Yang,X., Chen,Z. and Zhan,B.
    OTUB1-mediated deubiquitination of FOXM1 up-regulates ECT-2 to promote tumor progression in renal cell carcinoma
    Cell Biosci10, 50-50. PubMed  Europe PubMed DOI
2019
59. Gan,B.
    DUBbing ferroptosis in cancer cells
    Cancer Res79, 1749-1750. PubMed  Europe PubMed DOI
60. Huggins,M.A. and Hamilton,S.E.
    Deubiquitinase Otub1 negatively regulates IL-15 signaling in CD8 T cells and NK cells
    Cell Mol Immunol16, 846-847. PubMed  Europe PubMed DOI
61. Liu,T., Jiang,L., Tavana,O. and Gu,W.
    The deubiquitylase OTUB1 mediates ferroptosis via stabilization of SLC7A11
    Cancer Res79, 1913-1924. PubMed  Europe PubMed DOI
62. Pickel,C., Gunter,J., Ruiz-Serrano,A., Spielmann,P., Fabrizio,J.A., Wolski,W., Peet,D.J., Wenger,R.H. and Scholz,C.C.
    Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1
    Redox Biol26, 101265-101265. PubMed  Europe PubMed DOI
63. Saldana,M., VanderVorst,K., Berg,A.L., Lee,H. and Carraway,K.L.
    Otubain 1: a non-canonical deubiquitinase with an emerging role in cancer
    Endocr Relat Cancer26, R1-R1. PubMed  Europe PubMed DOI
64. Wang,X., Mulas,F., Yi,W., Brunn,A., Nishanth,G., Just,S., Waisman,A., Bruck,W., Deckert,M. and Schluter,D.
    OTUB1 inhibits CNS autoimmunity by preventing IFN-gamma-induced hyperactivation of astrocytes
    EMBO J38, e100947-e100947. PubMed  Europe PubMed DOI
65. Xuan,N.T., Trung,D.M., Minh,N.N., Nghia,V.X., Giang,N.V., Canh,N.X., Toan,N.L., Cam,T.D., Nga,N.T., Tien,T.V. and Hoang,N.H.
    Regulation of p38MAPK-mediated dendritic cell functions by the deubiquitylase otubain 1
    HLA93, 462-470. PubMed  Europe PubMed DOI
2018
66. Pasupala,N., Morrow,M.E., Que,L.T., Malynn,B.A., Ma,A. and Wolberger,C.
    OTUB1 non-catalytically stabilizes the E2 ubiquitin-conjugating enzyme UBE2E1 by preventing its autoubiquitination
    J Biol Chem293, 18285-18295. PubMed  Europe PubMed DOI
67. Zhao,L., Wang,X., Yu,Y., Deng,L., Chen,L., Peng,X., Jiao,C., Gao,G., Tan,X., Pan,W., Ge,X. and Wang,P.
    OTUB1 protein suppresses mTOR complex 1 (mTORC1) activity by deubiquitinating the mTORC1 inhibitor DEPTOR
    J Biol Chem293, 4883-4892. PubMed  Europe PubMed DOI
68. Zhou,H., Liu,Y., Zhu,R., Ding,F., Cao,X., Lin,D. and Liu,Z.
    OTUB1 promotes esophageal squamous cell carcinoma metastasis through modulating Snail stability
    Oncogene37, 3356-3368. PubMed  Europe PubMed DOI
2014
69. Sun,X.X. and Dai,M.S.
    Deubiquitinating enzyme regulation of the p53 pathway: a lesson from Otub1
    World J Biol Chem5, 75-84. PubMed  Europe PubMed DOI
2012
70. Juang,Y.C., Landry,M.C., Sanches,M., Vittal,V., Leung,C.C., Ceccarelli,D.F., Mateo,A.R., Pruneda,J.N., Mao,D.Y., Szilard,R.K., Orlicky,S., Munro,M., Brzovic,P.S., Klevit,R.E., Sicheri,F. and Durocher,D.
    OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function
    Mol Cell45, 384-397. PubMed  Europe PubMed DOI
71. Kessler,B.M.
    Otubains
    [ISSN:978-0-12-407743-0]3, 2113-2120. DOI
72. Sato,Y., Yamagata,A., Goto-Ito,S., Kubota,K., Miyamoto,R., Nakada,S. and Fukai,S.
    Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13
    J Biol Chem287, 25860-25868. PubMed  Europe PubMed DOI  S
73. Sun,X.X., Challagundla,K.B. and Dai,M.S.
    Positive regulation of p53 stability and activity by the deubiquitinating enzyme otubain 1
    EMBO J31, 576-592. PubMed  Europe PubMed DOI
2011
74. Blackford,A.N. and Stewart,G.S.
    When cleavage is not attractive: non-catalytic inhibition of ubiquitin chains at DNA double-strand breaks by OTUB1
    DNA Repair (Amst)10, 245-249. PubMed  Europe PubMed DOI
75. Yue,M.J., Mo,S.J., Song,P. and Gong,Y.Z.
    Identification of Z-OTU protein during zebrafish oogenesis and early embryogenesis
    Dongwuxue Yanjiu32, 386-390. PubMed  Europe PubMed DOI
2010
76. Edelmann,M.J., Kramer,H.B., Altun,M. and Kessler,B.M.
    Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion
    FEBS J277, 2515-2530. PubMed  Europe PubMed DOI
77. Li,S., Zheng,H., Mao,A.P., Zhong,B., Li,Y., Liu,Y., Gao,Y., Ran,Y., Tien,P. and Shu,H.B.
    Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6
    J Biol Chem285, 4291-4297. PubMed  Europe PubMed DOI
78. Nakada,S., Tai,I., Panier,S., Al-Hakim,A., Iemura,S., Juang,Y.C., O'Donnell,L., Kumakubo,A., Munro,M., Sicheri,F., Gingras,A.C., Natsume,T., Suda,T. and Durocher,D.
    Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1
    Nature466, 941-946. PubMed  Europe PubMed DOI
2009
79. Edelmann,M.J., Iphofer,A., Akutsu,M., Altun,M., di Gleria,K., Kramer,H.B., Fiebiger,E., Dhe-Paganon,S. and Kessler,B.M.
    Structural basis and specificity of human otubain 1-mediated deubiquitination
    Biochem J418, 379-390. PubMed  Europe PubMed DOI
80. Lin,J.T., Lineberry,N.B., Kattah,M.G., Su,L.L., Utz,P.J., Fathman,C.G. and Wu,L.
    Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression
    J Immunol182, 5919-5928. PubMed  Europe PubMed DOI
81. Stanisic,V., Malovannaya,A., Qin,J., Lonard,D.M. and O'Malley,B.W.
    OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity
    J Biol Chem284, 16135-16145. PubMed  Europe PubMed DOI
82. Wang,T., Yin,L., Cooper,E.M., Lai,M.Y., Dickey,S., Pickart,C.M., Fushman,D., Wilkinson,K.D., Cohen,R.E. and Wolberger,C.
    Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1
    J Mol Biol386, 1011-1023. PubMed  Europe PubMed DOI  P
2006
83. Juris,S.J., Shah,K., Shokat,K., Dixon,J.E. and Vacratsis,P.O.
    Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry
    FEBS Lett580, 179-183. PubMed  Europe PubMed DOI
2004
84. Soares,L., Seroogy,C., Skrenta,H., Anandasabapathy,N., Lovelace,P., Chung,C.D., Engleman,E. and Fathman,C.G.
    Two isoforms of otubain 1 regulate T cell anergy via GRAIL
    Nat Immunol5, 45-54. PubMed  Europe PubMed DOI
2003
85. Balakirev,M.Y., Tcherniuk,S.O., Jaquinod,M. and Chroboczek,J.
    Otubains: a new family of cysteine proteases in the ubiquitin pathway
    EMBO Rep4, 517-522. PubMed  Europe PubMed DOI  I
1989
86. Steinhauer,W.R., Walsh,R.C. and Kalfayan,L.J.
    Sequence and structure of the Drosophila melanogaster ovarian tumor gene and generation of an antibody specific for the ovarian tumor protein
    Mol Cell Biol9, 5726-5732. PubMed  Europe PubMed