Literature for peptidase C30.003: human coronavirus 229E main peptidase

(Topics flags: S Structure, T Target, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Martianez-Vendrell,X., van Kasteren,P.B., Myeni,S.K. and Kikkert,M.
   HCoV-229E Mpro Suppresses RLR-Mediated Innate Immune Signalling Through Cleavage of NEMO and Through Other Mechanisms
   Int J Mol Sci26, PubMed  Europe PubMed DOI
2024
2. Wang,M., Sun,X., Peng,S., Wang,F., Zhao,K. and Wang,D.
   Deciphering the cleavage sites of 3C-like protease in Gammacoronaviruses and Deltacoronaviruses
   Biochim Biophys Acta Proteins Proteom1873, 141057-141057. PubMed  Europe PubMed DOI
3. Xu,J., Zhu,Q., Li,W., Yin,X. and Li,J.
   Structural basis for the inhibition of the HCoV-NL63 main protease M(pro) by X77
   Biochem Biophys Res Commun724, 150231-150231. PubMed  Europe PubMed DOI  I
2023
4. Pathak,R.K., Kim,W.I. and Kim,J.M.
   Targeting the PEDV 3CL protease for identification of small molecule inhibitors: an insight from virtual screening, ADMET prediction, molecular dynamics, free energy landscape, and binding energy calculations
   J Biol Eng17, 29-29. PubMed  Europe PubMed DOI
2022
5. Feng,J., Li,D., Zhang,J., Yin,X. and Li,J.
   Crystal structure of SARS-CoV 3C-like protease with baicalein
   Biochem Biophys Res Commun611, 190-194. PubMed  Europe PubMed DOI  I
6. Zhu,Y., Scholle,F., Kisthardt,S.C. and Xie,D.Y.
   Flavonols and dihydroflavonols inhibit the main protease activity of SARS-CoV-2 and the replication of human coronavirus 229E
   Virology571, 21-33. PubMed  Europe PubMed DOI  I
2021
7. Gao,H., Zhang,Y., Jiang,H., Hu,X., Zhang,Y., Zhou,X., Zhong,F., Lin,C., Li,J., Luo,J. and Zhang,J.
   Crystal structures of human coronavirus NL63 main protease at different pH values
   Acta Crystallogr F Struct Biol Commun77, 348-355. PubMed  Europe PubMed DOI
8. Hu,Y., Ma,C., Szeto,T., Hurst,B., Tarbet,B. and Wang,J.
   Boceprevir, Calpain Inhibitors II and XII, and GC-376 Have Broad-Spectrum Antiviral Activity against Coronaviruses
   ACS Infect Dis7, 586-597. PubMed  Europe PubMed DOI  I
9. Jang,M., Park,R., Park,Y.I., Cha,Y.E., Yamamoto,A., Lee,J.I. and Park,J.
   EGCG, a green tea polyphenol, inhibits human coronavirus replication in vitro
   Biochem Biophys Res Commun547, 23-28. PubMed  Europe PubMed DOI  I
2020
10. Grottesi,A., Besker,N., Emerson,A., Manelfi,C., Beccari,A.R., Frigerio,F., Lindahl,E., Cerchia,C. and Talarico,C.
    Computational Studies of SARS-CoV-2 3CLpro: Insights from MD Simulations
    Int J Mol Sci21, PubMed  Europe PubMed DOI
11. Joshi,T., Joshi,T., Pundir,H., Sharma,P., Mathpal,S. and Chandra,S.
    Predictive modeling by deep learning, virtual screening and molecular dynamics study of natural compounds against SARS-CoV-2 main protease
    J Biomol Struct Dyn1-19. PubMed  Europe PubMed DOI
12. Koulgi,S., Jani,V., Uppuladinne,M., Sonavane,U., Nath,A.K., Darbari,H. and Joshi,R.
    Drug repurposing studies targeting SARS-CoV-2: an ensemble docking approach on drug target 3C-like protease (3CL(pro))
    J Biomol Struct Dyn1-21. PubMed  Europe PubMed DOI
13. Kozak,J.J., Gray,H.B. and Garza-Lopez,R.A.
    Structural stability of the SARS-CoV-2 main protease: Can metal ions affect function?
    J Inorg Biochem211, 111179-111179. PubMed  Europe PubMed DOI
14. Kumar,N., Sood,D., van der Spek,P.J., Sharma,H.S. and Chandra,R.
    Molecular Binding Mechanism and Pharmacology Comparative Analysis of Noscapine for Repurposing against SARS-CoV-2 Protease
    J Proteome Res PubMed  Europe PubMed DOI
15. Sharma,P., Vijayan,V., Pant,P., Sharma,M., Vikram,N., Kaur,P., Singh,T.P. and Sharma,S.
    Identification of potential drug candidates to combat COVID-19: a structural study using the main protease (mpro) of SARS-CoV-2
    J Biomol Struct Dyn1-11. PubMed  Europe PubMed DOI  T  I
2019
16. Zhou,J., Fang,L., Yang,Z., Xu,S., Lv,M., Sun,Z., Chen,J., Wang,D., Gao,J. and Xiao,S.
    Identification of novel proteolytically inactive mutations in coronavirus 3C-like protease using a combined approach
    FASEB J33, 14575-14587. PubMed  Europe PubMed DOI
2017
17. Jaru-Ampornpan,P., Jengarn,J., Wanitchang,A. and Jongkaewwattana,A.
    Porcine epidemic diarrhea virus (PEDV) 3C-Like protease-mediated nucleocapsid processing: a possible link to viral cell-culture adaptability
    J Virol91, e01660-16-e01660-16. PubMed  Europe PubMed DOI
18. Wang,F., Chen,C., Yang,K., Xu,Y., Liu,X., Gao,F., Liu,H., Chen,X., Zhao,Q., Liu,X., Cai,Y. and Yang,H.
    Michael acceptor-based peptidomimetic inhibitor of main protease from porcine epidemic diarrhea virus
    J Med Chem60, 3212-3216. PubMed  Europe PubMed DOI  S  I
2016
19. St John,S.E., Anson,B.J. and Mesecar,A.D.
    X-Ray structure and inhibition of 3C-like protease from porcine epidemic diarrhea virus
    Sci Rep6, 25961-25961. PubMed  Europe PubMed DOI  S  I
20. Wang,D., Fang,L., Shi,Y., Zhang,H., Gao,L., Peng,G., Chen,H., Li,K. and Xiao,S.
    Porcine epidemic diarrhea virus 3C-like protease regulates its interferon antagonism by cleaving NEMO
    J Virol90, 2090-2101. PubMed  Europe PubMed DOI
21. Wang,F., Chen,C., Tan,W., Yang,K. and Yang,H.
    Structure of main protease from human coronavirus NL63: insights for wide spectrum anti-coronavirus drug design
    Sci Rep6, 22677-22677. PubMed  Europe PubMed DOI  S  I
22. Ye,G., Deng,F., Shen,Z., Luo,R., Zhao,L., Xiao,S., Fu,Z.F. and Peng,G.
    Structural basis for the dimerization and substrate recognition specificity of porcine epidemic diarrhea virus 3C-like protease
    Virology494, 225-235. PubMed  Europe PubMed DOI  S
2015
23. Berry,M., Fielding,B. and Gamieldien,J.
    Human coronavirus OC43 3CL protease and the potential of ML188 as a broad-spectrum lead compound: Homology modelling and molecular dynamic studies
    BMC Struct Biol15, 8- PubMed  Europe PubMed DOI  I
2014
24. Tan,Y., Wang,F., Chen,X., Wang,J., Zhao,Q., Li,S., Wang,Z., Fu,S., Chen,C. and Yang,H.
    Crystallization and preliminary crystallographic study of porcine epidemic diarrhea virus main protease in complex with an inhibitor
    Acta Crystallogr F Struct Biol Commun70, 1608-1611. PubMed  Europe PubMed DOI  I
25. Wang,F., Tan,Y., Li,H., Chen,X., Wang,J., Li,S., Fu,S., Zhao,Q., Chen,C., Su,D. and Yang,H.
    Crystallization and preliminary crystallographic study of human coronavirus NL63 main protease in complex with an inhibitor
    Acta Crystallogr F Struct Biol Commun70, 1068-1071. PubMed  Europe PubMed DOI
2012
26. Stobart,C.C. and Denison,M.R.
    Coronavirus picornain-like cysteine proteinase
    [ISSN:978-0-12-407743-0]3, 2436-2441. DOI
2004
27. Denison,M.R.
    Coronavirus picornain-like cysteine proteinase
    [ISSN:0-12-079610-4]2, 1382-1385.  V
2003
28. [YEAR:13-6-2003]Anand,K., Ziebuhr,J., Wadhwani,P., Mesters,J.R. and Hilgenfeld,R.
    Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs
    Science300, 1763-1767. PubMed  Europe PubMed DOI  S
2001
29. Kocherhans,R., Bridgen,A., Ackermann,M. and Tobler,K.
    Completion of the porcine epidemic diarrhoea coronavirus (PEDV) genome sequence
    Virus Genes23, 137-144. PubMed  Europe PubMed DOI
1998
30. Collins,A.R. and Grubb,A.
    Cystatin D, a natural salivary cysteine protease inhibitor, inhibits coronavirus replication at its physiologic concentration
    Oral Microbiol Immunol13, 59-61. PubMed  Europe PubMed
31. Ziebuhr,J., Heusipp,G., Seybert,A. and Siddell,S.G.
    Substrate specificity of the human coronavirus 229E 3C-like proteinase
    Adv Exp Med Biol440, 115-120. PubMed  Europe PubMed
1997
32. Ziebuhr,J., Heusipp,G. and Siddell,S.G.
    Biosynthesis, purification, and characterization of the human coronavirus 229E 3C-like proteinase
    J Virol71, 3992-3997. PubMed  Europe PubMed