Literature for peptidase C14.018: caspase-14

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: A Assay, M Mutation, I Inhibitor, K Knockout, P Specificity, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Lu,X., Zhang,G., Yang,H., Shan,M., Zhang,X., Wang,Y., Bai,J. and Pan,Z.
    Tissue-specific and functional loci analysis of CASP14 gene in the sheep horn
    PLoS ONE19, e0310464-e0310464. PubMed  Europe PubMed DOI
  2. Steinbinder,J., Sachslehner,A.P., Holthaus,K.B. and Eckhart,L.
    Comparative genomics of sirenians reveals evolution of filaggrin and caspase-14 upon adaptation of the epidermis to aquatic life
    Sci Rep14, 9278-9278. PubMed  Europe PubMed DOI
  3. 2021
  4. Markiewicz,A., Sigorski,D., Markiewicz,M., Owczarczyk-Saczonek,A. and Placek,W.
    Caspase-14-From Biomolecular Basics to Clinical Approach. A Review of Available Data
    Int J Mol Sci22, PubMed  Europe PubMed DOI  V
  5. 2016
  6. Julien,O., Zhuang,M., Wiita,A.P., O'Donoghue,A.J., Knudsen,G.M., Craik,C.S. and Wells,J.A.
    Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles
    Proc Natl Acad Sci U S A113, E2001-E2010. PubMed  Europe PubMed DOI  P
  7. Neophytou,C.M., Theofilou,I. and Constantinou,A.I.
    The unknown caspase: the role of caspase-14 in cell death and disease
    Caspases: Roles and Significance in Cell Death and Disease69-88.
  8. Thyssen,J.P., Laursen,A.S., Husemoen,L.L., Stender,S., Szecsi,P.B., Menne,T., Johansen,J.D. and Linneberg,A.
    Variants in caspase-14 gene as risk factors for xerosis and atopic dermatitis
    J Eur Acad Dermatol Venereol30, 446-448. PubMed  Europe PubMed DOI  M
  9. 2015
  10. Strasser,B., Mlitz,V., Fischer,H., Tschachler,E. and Eckhart,L.
    Comparative genomics reveals conservation of filaggrin and loss of caspase-14 in dolphins
    Exp Dermatol24, 365-369. PubMed  Europe PubMed DOI
  11. 2014
  12. Beasley,S., El-Sherbiny,M., Megyerdi,S., El-Shafey,S., Choksi,K., Kaddour-Djebbar,I., Sheibani,N., Hsu,S. and Al-Shabrawey,M.
    Caspase-14 expression impairs retinal pigment epithelium barrier function: potential role in diabetic macular edema
    Biomed Res Int2014, 417986-417986. PubMed  Europe PubMed DOI
  13. Kubica,M., Hildebrand,F., Brinkman,B.M., Goossens,D., Del Favero,J., Vercammen,K., Cornelis,P., Schroder,J.M., Vandenabeele,P., Raes,J. and Declercq,W.
    The skin microbiome of caspase-14-deficient mice shows mild dysbiosis
    Exp Dermatol23, 561-567. PubMed  Europe PubMed DOI  K
  14. Yamamoto-Tanaka,M., Motoyama,A., Miyai,M., Matsunaga,Y., Matsuda,J., Tsuboi,R. and Hibino,T.
    Mesotrypsin and caspase-14 participate in prosaposin processing: potential relevance to epidermal permeability barrier formation
    J Biol Chem289, 20026-20038. PubMed  Europe PubMed DOI
  15. Yamamoto-Tanaka,M. and Hibino,T.
    Caspase-14 protocols
    Methods Mol Biol1133, 89-100. PubMed  Europe PubMed DOI
  16. 2013
  17. Brocklehurst,K. and Philpott,M.P.
    Cysteine proteases: mode of action and role in epidermal differentiation
    Cell Tissue Res351, 237-244. PubMed  Europe PubMed DOI
  18. Devos,M., De Groote,P., Gilbert,B., Bruggeman,I., Leurs,K., Lippens,S., Vandenabeele,P. and Declercq,W.
    Caspase-14 overexpression in hairless mice is not involved in utricle formation
    Exp Dermatol22, 484-486. PubMed  Europe PubMed DOI
  19. Hoste,E., Denecker,G., Gilbert,B., Van Nieuwerburgh,F., van der Fits,L., Asselbergh,B., De Rycke,R., Hachem,J.P., Deforce,D., Prens,E.P., Vandenabeele,P. and Declercq,W.
    Caspase-14-deficient mice are more prone to the development of parakeratosis
    J Invest Dermatol133, 742-750. PubMed  Europe PubMed DOI  K
  20. Jiang,Y.J., Kim,P., Uchida,Y., Elias,P.M., Bikle,D.D., Grunfeld,C. and Feingold,K.R.
    Ceramides stimulate caspase-14 expression in human keratinocytes
    Exp Dermatol22, 113-118. PubMed  Europe PubMed DOI
  21. Kataoka,S., Hattori,K., Date,A. and Tamura,H.
    Human keratinocyte caspase-14 expression is altered in human epidermal 3D models by dexamethasone and by natural products used in cosmetics
    Arch Dermatol Res305, 683-689. PubMed  Europe PubMed DOI
  22. Wu,Y.H., Lo,H.F., Chen,S.H. and Chen,H.
    Caspase-14 suppresses GCM1 acetylation and inhibits placental cell differentiation
    FASEB J27, 2818-2828. PubMed  Europe PubMed DOI
  23. 2012
  24. Declercq,W.
    Caspase-14
    [ISSN:978-0-12-407743-0]3, 2280-2285. DOI
  25. Devos,M., Prawitt,J., Staumont-Salle,D., Hoste,E., Fleury,S., Bouchaert,E., Gilbert,B., Lippens,S., Vandenabeele,P., Dombrowicz,D. and Declercq,W.
    Filaggrin degradation by caspase-14 is required for UVB photoprotection but does not influence allergic sensitization in a mouse model of atopic dermatitis
    J Invest Dermatol132, 2857-2860. PubMed  Europe PubMed DOI
  26. Kazem,S., van der Meijden,E., Struijk,L., de Gruijl,F.R. and Feltkamp,M.C.
    Human papillomavirus 8 E6 disrupts terminal skin differentiation and prevents pro-caspase-14 cleavage
    Virus Res163, 609-616. PubMed  Europe PubMed DOI
  27. Yamamoto,M., Miyai,M., Matsumoto,Y., Tsuboi,R. and Hibino,T.
    Kallikrein-related peptidase-7 regulates caspase-14 maturation during keratinocyte terminal differentiation by generating an intermediate form
    J Biol Chem287, 32825-32834. PubMed  Europe PubMed DOI
  28. 2011
  29. Eckhart,L. and Tschachler,E.
    Cuts by caspase-14 control the proteolysis of filaggrin
    J Invest Dermatol131, 2173-2175. PubMed  Europe PubMed DOI
  30. Fang,H.Y., Chen,C.Y., Hung,M.F., Hsiao,Y.T., Chiang,T.C., Lin,T.Y., Chang,H.W., Chow,K.C. and Ko,W.J.
    Caspase-14 is an anti-apoptotic protein targeting apoptosis-inducing factor in lung adenocarcinomas
    Oncol Rep26, 359-369. PubMed  Europe PubMed DOI
  31. Hoste,E., Kemperman,P., Devos,M., Denecker,G., Kezic,S., Yau,N., Gilbert,B., Lippens,S., De Groote,P., Roelandt,R., Van Damme,P., Gevaert,K., Presland,R.B., Takahara,H., Puppels,G., Caspers,P., Vandenabeele,P. and Declercq,W.
    Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin
    J Invest Dermatol131, 2233-2241. PubMed  Europe PubMed DOI
  32. Yamamoto,M., Kamata,Y., Iida,T., Fukushima,H., Nomura,J., Saito,M., Tajima,M., Okubo,Y., Momoi,T., Tsuboi,R. and Hibino,T.
    Quantification of activated and total caspase-14 with newly developed ELISA systems in normal and atopic skin
    J Dermatol Sci61, 110-117. PubMed  Europe PubMed DOI  A
  33. 2010
  34. Bennett,K., Callard,R., Heywood,W., Harper,J., Jayakumar,A., Clayman,L., Di,W.L. and Mills,K.
    New role for LEKTI in skin barrier formation: label-free quantitative proteomic identification of caspase 14 as a novel target for the protease inhibitor LEKTI
    J Proteome Res9, 4289-4294. PubMed  Europe PubMed DOI
  35. Hibino,T., Fujita,E., Tsuji,Y., Nakanishi,J., Iwaki,H., Katagiri,C. and Momoi,T.
    Purification and characterization of active caspase-14 from human epidermis and development of the cleavage site-directed antibody
    J Cell Biochem109, 487-497. PubMed  Europe PubMed DOI
  36. 2009
  37. Presland,R.B.
    Function of filaggrin and caspase-14 in formation and maintenance of the epithelial barrier
    Dermatol Sin27, 1-14.
  38. White,L.J., Declercq,W., Arfuso,F., Charles,A.K. and Dharmarajan,A.M.
    Function of caspase-14 in trophoblast differentiation
    Reprod Biol Endocrinol7, 98-98. PubMed  Europe PubMed DOI
  39. Wu,M., Kodani,I., Dickinson,D., Huff,F., Ogbureke,K.U., Qin,H., Arun,S., Dulebohn,R., Al-Shabrawey,M., Tawfik,A., Prater,S., Lewis,J., Wataha,J., Messer,R. and Hsu,S.
    Exogenous expression of caspase-14 induces tumor suppression in human salivary cancer cells by inhibiting tumor vascularization
    Anticancer Res29, 3811-3818. PubMed  Europe PubMed
  40. 2008
  41. Denecker,G., Ovaere,P., Vandenabeele,P. and Declercq,W.
    Caspase-14 reveals its secrets
    J Cell Biol180, 451-458. PubMed  Europe PubMed DOI  K  V
  42. 2007
  43. Denecker,G., Hoste,E., Gilbert,B., Hochepied,T., Ovaere,P., Lippens,S., Van den Broecke,C., Van Damme,P., D'Herde,K., Hachem,J.P., Borgonie,G., Presland,R.B., Schoonjans,L., Libert,C., Vandekerckhove,J., Gevaert,K., Vandenabeele,P. and Declercq,W.
    Caspase-14 protects against epidermal UVB photodamage and water loss
    Nat Cell Biol9, 666-674. PubMed  Europe PubMed DOI  K
  44. Nicotera,P. and Melino,G.
    Caspase-14 and epidermis maturation
    Nat Cell Biol9, 621-622. PubMed  Europe PubMed DOI
  45. Raymond,A.A., Mechin,M.C., Nachat,R., Toulza,E., Tazi-Ahnini,R., Serre,G. and Simon,M.
    Nine procaspases are expressed in normal human epidermis, but only caspase-14 is fully processed
    Br J Dermatol156, 420-427. PubMed  Europe PubMed DOI
  46. White,L., Dharmarajan,A. and Charles,A.
    Caspase-14: a new player in cytotrophoblast differentiation
    Reprod Biomed Online14, 300-307. PubMed  Europe PubMed
  47. Yoo,N.J., Soung,Y.H., Lee,S.H., Jeong,E.G. and Lee,S.H.
    Mutational analysis of caspase-14 gene in common carcinomas
    Pathology39, 330-333. PubMed  Europe PubMed DOI
  48. 2006
  49. [YEAR:10-7-2006]Park,K., Kuechle,M.K., Choe,Y., Craik,C.S., Lawrence,O.T. and Presland,R.B.
    Expression and characterization of constitutively active human caspase-14
    Biochem Biophys Res Commun347, 941-948. PubMed  Europe PubMed DOI  E  I
  50. 2005
  51. Fischer,H., Rossiter,H., Ghannadan,M., Jaeger,K., Barresi,C., Declercq,W., Tschachler,E. and Eckhart,L.
    Caspase-14 but not caspase-3 is processed during the development of fetal mouse epidermis
    Differentiation73, 406-413. PubMed  Europe PubMed DOI
  52. Kam,D.W., Charles,A.K. and Dharmarajan,A.M.
    Caspase-14 expression in the human placenta
    Reprod Biomed Online11, 236-243. PubMed  Europe PubMed
  53. Walsh,D.S., Borke,J.L., Singh,B.B., Do,N.N., Balagon,M.V., Abalos,R.M. and Hsu,S.D.
    Psoriasis is characterized by altered epidermal expression of caspase 14, a novel regulator of keratinocyte terminal differentiation and barrier formation
    J Dermatol Sci37, 61-63. PubMed  Europe PubMed DOI
  54. 2004
  55. Alibardi,L., Dockal,M., Reinisch,C., Tschachler,E. and Eckhart,L.
    Ultrastructural localization of caspase-14 in human epidermis
    J Histochem Cytochem52, 1561-1574. PubMed  Europe PubMed DOI
  56. [YEAR:19-11-2004]Fischer,H., Stichenwirth,M., Dockal,M., Ghannadan,M., Buchberger,M., Bach,J., Kapetanopoulos,A., Declercq,W., Tschachler,E. and Eckhart,L.
    Stratum corneum-derived caspase-14 is catalytically active
    FEBS Lett577, 446-450. PubMed  Europe PubMed DOI
  57. Lippens,S., Kockx,M., Denecker,G., Knaapen,M., Verheyen,A., Christiaen,R., Tschachler,E., Vandenabeele,P. and Declercq,W.
    Vitamin D3 induces caspase-14 expression in psoriatic lesions and enhances caspase-14 processing in organotypic skin cultures
    Am J Pathol165, 833-841. PubMed  Europe PubMed DOI
  58. [YEAR:17-8-2004]Mikolajczyk,J., Scott,F.L., Krajewski,S., Sutherlin,D.P. and Salvesen,G.S.
    Activation and substrate specificity of caspase-14
    Biochemistry43, 10560-10569. PubMed  Europe PubMed DOI
  59. 2003
  60. Lippens,S., VandenBroecke,C., Van Damme,E., Tschachler,E., Vandenabeele,P. and Declercq,W.
    Caspase-14 is expressed in the epidermis, the choroid plexus, the retinal pigment epithelium and thymic Hassall's bodies
    Cell Death Differ10, 257-259. PubMed  Europe PubMed DOI
  61. 2002
  62. [YEAR:30-8-2002]Chien,A.J., Presland,R.B. and Kuechle,M.K.
    Processing of native caspase-14 occurs at an atypical cleavage site in normal epidermal differentiation
    Biochem Biophys Res Commun296, 911-917. PubMed  Europe PubMed DOI  P
  63. Rendl,M., Ban,J., Mrass,P., Mayer,C., Lengauer,B., Eckhart,L., Declerq,W. and Tschachler,E.
    Caspase-14 expression by epidermal keratinocytes is regulated by retinoids in a differentiation-associated manner
    J Invest Dermatol119, 1150-1155. PubMed  Europe PubMed DOI
  64. 2001
  65. Kuechle,M.K., Predd,H.M., Fleckman,P., Dale,B.A. and Presland,R.B.
    Caspase-14, a keratinocyte specific caspase: mRNA splice variants and expression pattern in embryonic and adult mouse
    Cell Death Differ8, 868-870. PubMed  Europe PubMed DOI
  66. 2000
  67. Eckhart,L., Declercq,W., Ban,J., Rendl,M., Lengauer,B., Mayer,C., Lippens,S., Vandenabeele,P. and Tschachler,E.
    Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation
    J Invest Dermatol115, 1148-1151. PubMed  Europe PubMed DOI
  68. [YEAR:2-11-2000]Eckhart,L., Ban,J., Fischer,H. and Tschachler,E.
    Caspase-14: analysis of gene structure and mRNA expression during keratinocyte differentiation
    Biochem Biophys Res Commun277, 655-659. PubMed  Europe PubMed DOI
  69. Lippens,S., Kockx,M., Knaapen,M., Mortier,L., Polakowska,R., Verheyen,A., Garmyn,M., Zwijsen,A., Formstecher,P., Huylebroeck,D., Vandenabeele,P. and Declercq,W.
    Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing
    Cell Death Differ7, 1218-1224. PubMed  Europe PubMed DOI
  70. 1998
  71. [YEAR:15-11-1998]Ahmad,M., Srinivasula,S.M., Hegde,R., Mukattash,R., Fernandes-Alnemri,T. and Alnemri,E.S.
    Identification and characterization of murine caspase-14, a new member of the caspase family
    Cancer Res58, 5201-5205. PubMed  Europe PubMed
  72. [YEAR:6-11-1998]Hu,S., Snipas,S.J., Vincenz,C., Salvesen,G. and Dixit,V.M.
    Caspase-14 is a novel developmentally regulated protease
    J Biol Chem273, 29648-29653. PubMed  Europe PubMed DOI
  73. Van de Craen,M., Van Loo,G., Pype,S., van Criekinge,W., van den Brande,I., Molemans,F., Fiers,W., Declercq,W. and Vandenabeele,P.
    Identification of a new caspase homologue: caspase-14
    Cell Death Differ5, 838-846. PubMed  Europe PubMed DOI