Merops Switch to
Inhibitors

Peptidase

Family Clan SEARCHES BLAST
MEROPS SUBMISSIONS

Other
information

Literature for peptidase C14.012: caspase-11

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: M Mutation, P Specificity, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Shi,Y., He,T., Liu,H., Li,X., Li,Z., Wen,Q., Dai,Z., Sun,X., Tan,Q., Yang,W., Jiang,Y., Liu,Y., Yuan,H., Lei,F., Yi,Y. and Cai,J.
    Ganglioside GA2-mediated caspase-11 activation drives macrophage pyroptosis aggravating intimal hyperplasia after arterial injury
    Int J Biol Sci21, 433-453. PubMed  Europe PubMed DOI  K
    2. 2024
  2. Ai,Y., Meng,Y., Yan,B., Zhou,Q. and Wang,X.
    The biochemical pathways of apoptotic, necroptotic, pyroptotic, and ferroptotic cell death
    Mol Cell84, 170-179. PubMed  Europe PubMed DOI  V
  3. Akuma,D.C., Wodzanowski,K.A., Schwartz Wertman,R., Exconde,P.M., Vazquez Marrero,V.R., Odunze,C.E., Grubaugh,D., Shin,S., Taabazuing,C. and Brodsky,I.E.
    Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS
    elife13, PubMed  Europe PubMed DOI
  4. Daily,K.P., Badr,A., Eltobgy,M., Estfanous,S., Whitham,O., Tan,M.H., Carafice,C., Krause,K., McNamara,A., Hamilton,K., Houle,S., Gupta,S., Gupta,G.A., Madhu,S., Fitzgerald,J., Saadey,A.A., Laster,B., Yan,P., Webb,A., Zhang,X., Pietrzak,M., Kokiko-Cochran,O.N., Ghoneim,H.E. and Amer,A.O.
    DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-beta deposition in Alzheimer's disease
    Alzheimers Res Ther16, 29-29. PubMed  Europe PubMed DOI
  5. Eckhart,L. and Fischer,H.
    Caspase-5: Structure, Pro-Inflammatory Activity and Evolution
    Biomolecules14, PubMed  Europe PubMed DOI  V
  6. Tan,J., Feng,L., Ragavan,N.D., Chai Theam,O. and Li,X.
    The promotive effect of Caspase-11 overexpression in a rat model of chronic kidney disease and the therapeutic efficacy of exosome-delivered siRNA in inhibiting Caspase-11
    Biochem Biophys Res Commun741, 151013-151013. PubMed  Europe PubMed DOI
  7. Wright,S.S., Wang,C., Ta,A., Havira,M.S., Ruan,J., Rathinam,V.A. and Vanaja,S.K.
    A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis
    Cell Rep43, 114004-114004. PubMed  Europe PubMed DOI
    8. 2023
  8. Cho,H.J., Kim,E. and Yi,Y.S.
    Korean Red Ginseng Saponins Play an Anti-Inflammatory Role by Targeting Caspase-11 Non-Canonical Inflammasome in Macrophages
    Int J Mol Sci24, PubMed  Europe PubMed DOI
  9. Jiao,P., Li,Z., Li,B. and Jiao,X.
    The Role of Caspase-11 and Pyroptosis in the Regulation of Inflammation in Peri-Implantitis
    J Inflamm Res16, 4471-4479. PubMed  Europe PubMed DOI
  10. Karasawa,T., Komada,T., Baatarjav,C., Aizawa,E., Mizushina,Y., Fujimura,K., Gunji,Y., Komori,S., Aizawa,H., Jing Tao,C.B., Matsumura,T. and Takahashi,M.
    Caspase-11 deficiency attenuates neutrophil recruitment into the atherosclerotic lesion in apolipoprotein E-deficient mice
    Biochem Biophys Res Commun686, 149158-149158. PubMed  Europe PubMed DOI
  11. Sahoo,G., Samal,D., Khandayataray,P. and Murthy,M.K.
    A Review on Caspases: Key Regulators of Biological Activities and Apoptosis
    Mol Neurobiol60, 5805-5837. PubMed  Europe PubMed DOI  V
  12. Shi,X., Sun,Q., Hou,Y., Zeng,H., Cao,Y., Dong,M., Ding,J. and Shao,F.
    Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome
    Nature624, 442-450. PubMed  Europe PubMed DOI
  13. Yi,Y.S.
    Regulatory Roles of Flavonoids in Caspase-11 Non-Canonical Inflammasome-Mediated Inflammatory Responses and Diseases
    Int J Mol Sci24, PubMed  Europe PubMed DOI  V
    14. 2022
  14. Eltobgy,M.M., Zani,A., Kenney,A.D., Estfanous,S., Kim,E., Badr,A., Carafice,C., Daily,K., Whitham,O., Pietrzak,M., Webb,A., Kawahara,J., Eddy,A.C., Denz,P., Lu,M., Kc,M., Peeples,M.E., Li,J., Zhu,J., Que,J., Robinson,R., Rosas Mejia,O., Rayner,R.E., Hall-Stoodley,L., Seveau,S., Gavrilin,M.A., Zhang,X., Thomas,J., Kohlmeier,J.E., Suthar,M.S., Oltz,E., Tedeschi,A., Robledo-Avila,F.H., Partida-Sanchez,S., Hemann,E.A., Abdelrazik,E., Forero,A., Nimjee,S.M., Boyaka,P.N., Cormet-Boyaka,E., Yount,J.S. and Amer,A.O.
    Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and immunothrombosis
    Proc Natl Acad Sci U S A119, e2202012119-e2202012119. PubMed  Europe PubMed DOI
  15. Hu,Y., Jiang,Y., Li,S., Ma,X., Chen,M., Yang,R., Wen,S., Moynagh,P.N., Wang,B., Hu,G. and Yang,S.
    The Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/11
    Proc Natl Acad Sci U S A119, e2210809119-e2210809119. PubMed  Europe PubMed DOI
  16. Ross,C., Chan,A.H., von Pein,J.B., Maddugoda,M.P., Boucher,D. and Schroder,K.
    Inflammatory Caspases: Toward a Unified Model for Caspase Activation by Inflammasomes
    Annu Rev Immunol PubMed  Europe PubMed DOI  V
  17. Smith,A.P. and Creagh,E.M.
    Caspase-4 and -5 Biology in the Pathogenesis of Inflammatory Bowel Disease
    Front Pharmacol13, 919567-919567. PubMed  Europe PubMed DOI  V
  18. Tsutsuki,H., Zhang,T., Yahiro,K., Ono,K., Fujiwara,Y., Iyoda,S., Wei,F.Y., Monde,K., Seto,K., Ohnishi,M., Oshiumi,H., Akaike,T. and Sawa,T.
    Subtilase cytotoxin from Shiga-toxigenic Escherichia coli impairs the inflammasome and exacerbates enteropathogenic bacterial infection
    iScience25, 104050-104050. PubMed  Europe PubMed DOI
  19. Wang,Z., Chan,W. and Yue,Y.
    A significant other: Non-canonical caspase-4/5/11 inflammasome in periodontitis
    Oral Dis PubMed  Europe PubMed DOI  V
  20. Yi,Y.S.
    Dual roles of the caspase-11 non-canonical inflammasome in inflammatory bowel disease
    Int Immunopharmacol108, 108739-108739. PubMed  Europe PubMed DOI  V
  21. Yi,Y.S.
    Regulatory Roles of Caspase-11 Non-Canonical Inflammasome in Inflammatory Liver Diseases
    Int J Mol Sci23, PubMed  Europe PubMed DOI  V
  22. Yin,F., Zheng,P.Q., Zhao,L.Q., Wang,Y.Z., Miao,N.J., Zhou,Z.L., Cheng,Q., Chen,P.P., Xie,H.Y., Li,J.Y., Ni,J.Y., Zhou,L., Zhang,W., Wang,X.X., Liu,J. and Lu,L.M.
    Caspase-11 promotes NLRP3 inflammasome activation via the cleavage of pannexin1 in acute kidney disease
    Acta Pharmacol Sin43, 86-95. PubMed  Europe PubMed DOI  K
    23. 2021
  23. Agnew,A., Nulty,C. and Creagh,E.M.
    Regulation, Activation and Function of Caspase-11 during Health and Disease
    Int J Mol Sci22, PubMed  Europe PubMed DOI  V
  24. Bateman,G., Hill,B., Knight,R. and Boucher,D.
    Great balls of fire: activation and signalling of inflammatory caspases
    Biochem Soc Trans49, 1311-1324. PubMed  Europe PubMed DOI  V
  25. Biasizzo,M., Trstenjak-Prebanda,M., Dolinar,K., Pirkmajer,S., Zavrsnik,J., Turk,B. and Kopitar-Jerala,N.
    Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice
    Cells10, PubMed  Europe PubMed DOI
  26. Li,Z., Liu,W., Fu,J., Cheng,S., Xu,Y., Wang,Z., Liu,X., Shi,X., Liu,Y., Qi,X., Liu,X., Ding,J. and Shao,F.
    Shigella evades pyroptosis by arginine ADP-riboxanation of caspase-11
    Nature599, 290-295. PubMed  Europe PubMed DOI
  27. Lima,C., Falcao,M.A.P., Andrade-Barros,A.I., Seni-Silva,A.C., Grund,L.Z., Balogh,E., Conceicao,K., Queniaux,V.F., Ryffel,B. and Lopes-Ferreira,M.
    Natterin an aerolysin-like fish toxin drives IL-1beta-dependent neutrophilic inflammation mediated by caspase-1 and caspase-11 activated by the inflammasome sensor NLRP6
    Int Immunopharmacol91, 107287-107287. PubMed  Europe PubMed DOI
  28. Wu,J., Sun,J. and Meng,X.
    Pyroptosis by caspase-11 inflammasome-Gadermin D pathway in autoimmune diseases
    Pharmacol Res105408-105408. PubMed  Europe PubMed DOI  V
  29. Wu,M., Shi,J., He,S., Wang,D., Zhang,N., Wang,Z., Yang,F., He,J., Hu,D., Yang,X. and Yuan,C.
    cGAS promotes sepsis in radiotherapy of cancer by up-regulating caspase-11 signaling
    Biochem Biophys Res Commun551, 86-92. PubMed  Europe PubMed DOI
  30. Yi,Y.S.
    Caspase-11 Noncanonical Inflammasome: A Novel Key Player in Murine Models of Neuroinflammation and Multiple Sclerosis
    Neuroimmunomodulation1-9. PubMed  Europe PubMed DOI  V
  31. Zheng,M., Karki,R., Kancharana,B., Berns,H., Pruett-Miller,S.M. and Kanneganti,T.D.
    Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections
    J Biol Chem297, 101379-101379. PubMed  Europe PubMed DOI
    32. 2020
  32. Abu Khweek,A. and Amer,A.O.
    Pyroptotic and non-pyroptotic effector functions of caspase-11
    Immunol Reve12910-e12910. PubMed  Europe PubMed DOI
  33. Bibo-Verdugo,B., Snipas,S.J., Kolt,S., Poreba,M. and Salvesen,G.S.
    Extended subsite profiling of the pyroptosis effector protein gasdermin D reveals a region recognized by inflammatory caspase-11
    J Biol Chem PubMed  Europe PubMed DOI
  34. Chao,L., Li,Z., Zhou,J., Chen,W., Li,Y., Lv,W., Guo,A., Qu,Q. and Guo,S.
    Shen-Ling-Bai-Zhu-San Improves Dextran Sodium Sulfate-Induced Colitis by Inhibiting Caspase-1/Caspase-11-Mediated Pyroptosis
    Front Pharmacol11, 814-814. PubMed  Europe PubMed DOI
  35. Fagenson,A.M., Xu,K., Saaoud,F., Nanayakkara,G., Jhala,N.C., Liu,L., Drummer,C., Sun,Y., Lau,K.N., Di Carlo,A., Jiang,X., Wang,H., Karhadkar,S.S. and Yang,X.
    Liver Ischemia Reperfusion Injury, Enhanced by Trained Immunity, Is Attenuated in Caspase 1/Caspase 11 Double Gene Knockout Mice
    Pathogens9, PubMed  Europe PubMed DOI
  36. Kovacs,S.B., Oh,C., Maltez,V.I., McGlaughon,B.D., Verma,A., Miao,E.A. and Aachoui,Y.
    Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
    Cell Rep32, 107967-107967. PubMed  Europe PubMed DOI
  37. Peng,Y., Gao,M., Liu,Y., Qiu,X., Cheng,X., Yang,X., Chen,F. and Wang,E.
    Bacterial outer membrane vesicles induce disseminated intravascular coagulation through the caspase-11-gasdermin D pathway
    Thromb Res196, 159-166. PubMed  Europe PubMed DOI
  38. Sachdev,U., Ferrari,R., Cui,X., Pius,A., Sahu,A., Reynolds,M., Liao,H., Sun,P., Shinde,S., Ambrosio,F., Shiva,S., Loughran,P. and Scott,M.
    Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine
    Mol Med26, 69-69. PubMed  Europe PubMed DOI  K
  39. Sakaguchi,N., Sasai,M., Bando,H., Lee,Y., Pradipta,A., Ma,J.S. and Yamamoto,M.
    Role of Gate-16 and Gabarap in Prevention of Caspase-11-Dependent Excess Inflammation and Lethal Endotoxic Shock
    Front Immunol11, 561948-561948. PubMed  Europe PubMed DOI
  40. Thorstenberg,M.L., Martins,M.D.A., Figliuolo,V., Silva,C.L.M., Savio,L.E.B. and Coutinho-Silva,R.
    P2Y2 Receptor Induces L. amazonensis Infection Control in a Mechanism Dependent on Caspase-1 Activation and IL-1beta Secretion
    Mediators Inflamm2020, 2545682-2545682. PubMed  Europe PubMed DOI
  41. Wang,X., Liu,Z. and Shen,L.
    [Isoflurane preconditioning inhibits caspase-11-related noncanonical pyroptosis pathway to alleviate hepatic ischemia-reperfusion injury in mice]
    Nan Fang Yi Ke Da Xue Xue Bao40, 670-675. PubMed  Europe PubMed DOI
  42. Wang,Y., Zhang,M., Sun,Y., Wang,X., Song,Z., Li,H., Liu,K. and Li,Z.
    Role of short-wavelength blue light in the formation of cataracts and the expression of caspase-1, caspase-11, Gasdermin D in rat lens epithelial cells: insights into a novel pathogenic mmechanism of cataracts
    BMC Ophthalmol20, 289-289. PubMed  Europe PubMed DOI  I
  43. Yi,Y.S.
    Caspase-11 non-canonical inflammasome: emerging activator and regulator of infection-mediated inflammatory responses
    Int J Mol Sci21, PubMed  Europe PubMed DOI
  44. Zaslona,Z., Flis,E., Nulty,C., Kearney,J., FitzGerald,R., Douglas,A.R., McNamara,D., Smith,S., O'Neill,L.A.J. and Creagh,E.M.
    Caspase-4: A Therapeutic Target for Peptic Ulcer Disease
    Immunohorizons4, 627-633. PubMed  Europe PubMed DOI
    45. 2019
  45. Huang,X., Feng,Y., Xiong,G., Whyte,S., Duan,J., Yang,Y., Wang,K., Yang,S., Geng,Y., Ou,Y. and Chen,D.
    Caspase-11, a specific sensor for intracellular lipopolysaccharide recognition, mediates the non-canonical inflammatory pathway of pyroptosis
    Cell Biosci9, 31-31. PubMed  Europe PubMed DOI
  46. Lu,Y., Meng,R., Wang,X., Xu,Y., Tang,Y., Wu,J., Xue,Q., Yu,S., Duan,M., Shan,D., Wang,Q., Wang,H., Billiar,T.R., Xiao,X., Chen,F. and Lu,B.
    Caspase-11 signaling enhances graft-versus-host disease
    Nat Commun10, 4044-4044. PubMed  Europe PubMed DOI
    47. 2018
  47. Baker,P.J. and Masters,S.L.
    Caspase substrates won't be defined by a four-letter code
    J Biol Chem293, 7068-7069. PubMed  Europe PubMed DOI  P
  48. Chen,N., Ou,Z., Zhang,W., Zhu,X., Li,P. and Gong,J.
    Cathepsin B regulates non-canonical NLRP3 inflammasome pathway by modulating activation of caspase-11 in Kupffer cells
    Cell Prolife12487-e12487. PubMed  Europe PubMed DOI
  49. Lee,B.L., Stowe,I.B., Gupta,A., Kornfeld,O.S., Roose-Girma,M., Anderson,K., Warming,S., Zhang,J., Lee,W.P. and Kayagaki,N.
    Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation
    J Exp Med215, 2279-2288. PubMed  Europe PubMed DOI
  50. Ramirez,M.L.G., Poreba,M., Snipas,S.J., Groborz,K., Drag,M. and Salvesen,G.S.
    Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1
    J Biol Chem293, 7058-7067. PubMed  Europe PubMed DOI  P
  51. Ross,C., Chan,A.H., Von Pein,J., Boucher,D. and Schroder,K.
    Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome
    Life Sci Alliance1, e201800237-e201800237. PubMed  Europe PubMed DOI
  52. Tang,Y., Zhang,R., Xue,Q., Meng,R., Wang,X., Yang,Y., Xie,L., Xiao,X., Billiar,T.R. and Lu,B.
    TRIF signaling is required for caspase-11-dependent immune responses and lethality in sepsis
    Mol Med24, 66-66. PubMed  Europe PubMed DOI
  53. Yi,Y.S.
    Regulatory roles of the caspase-11 non-canonical inflammasome in inflammatory diseases
    Immune Netw18, e41-e41. PubMed  Europe PubMed DOI
    54. 2015
  54. Caution,K., Gavrilin,M.A., Tazi,M., Kanneganti,A., Layman,D., Hoque,S., Krause,K. and Amer,A.O.
    Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance
    Sci Rep5, 18479-18479. PubMed  Europe PubMed DOI
  55. Cerqueira,D.M., Pereira,M.S., Silva,A.L., Cunha,L.D. and Zamboni,D.S.
    Caspase-1 but not caspase-11 is required for NLRC4-mediated pyroptosis and restriction of infection by flagellated Legionella species in mouse macrophages and in vivo
    J Immunol195, 2303-2311. PubMed  Europe PubMed DOI
  56. de Gassart,A. and Martinon,F.
    Pyroptosis: caspase-11 unlocks the gates of death
    Immunity43, 835-837. PubMed  Europe PubMed DOI
  57. Hendrikx,T., Jeurissen,M.L., van Gorp,P.J., Gijbels,M.J., Walenbergh,S.M., Houben,T., van Gorp,R., Pottgens,C.C., Stienstra,R., Netea,M.G., Hofker,M.H., Donners,M.M. and Shiri-Sverdlov,R.
    Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr(-/-) mice
    FEBS J282, 2327-2338. PubMed  Europe PubMed DOI  K
  58. Huang,W., Xie,W.B., Qiao,D., Qiu,P., Huang,E., Li,B., Chen,C., Liu,C., Wang,Q., Lin,Z. and Wang,H.
    Caspase-11 plays an essential role in methamphetamine-induced dopaminergic neuron apoptosis
    Toxicol Sci145, 68-79. PubMed  Europe PubMed DOI
  59. Kayagaki,N., Stowe,I.B., Lee,B.L., O'Rourke,K., Anderson,K., Warming,S., Cuellar,T., Haley,B., Roose-Girma,M., Phung,Q.T., Liu,P.S., Lill,J.R., Li,H., Wu,J., Kummerfeld,S., Zhang,J., Lee,W.P., Snipas,S.J., Salvesen,G.S., Morris,L.X., Fitzgerald,L., Zhang,Y., Bertram,E.M., Goodnow,C.C. and Dixit,V.M.
    Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
    Nature526, 666-671. PubMed  Europe PubMed DOI
  60. Shi,J., Zhao,Y., Wang,K., Shi,X., Wang,Y., Huang,H., Zhuang,Y., Cai,T., Wang,F. and Shao,F.
    Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
    Nature526, 660-665. PubMed  Europe PubMed DOI
    61. 2014
  61. Knodler,L.A., Crowley,S.M., Sham,H.P., Yang,H., Wrande,M., Ma,C., Ernst,R.K., Steele-Mortimer,O., Celli,J. and Vallance,B.A.
    Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens
    Cell Host Microbe16, 249-256. PubMed  Europe PubMed DOI
  62. Py,B.F., Jin,M., Desai,B.N., Penumaka,A., Zhu,H., Kober,M., Dietrich,A., Lipinski,M.M., Henry,T., Clapham,D.E. and Yuan,J.
    Caspase-11 controls interleukin-1beta release through degradation of TRPC1
    Cell Rep6, 1122-1128. PubMed  Europe PubMed DOI
    63. 2013
  63. Aachoui,Y., Leaf,I.A., Hagar,J.A., Fontana,M.F., Campos,C.G., Zak,D.E., Tan,M.H., Cotter,P.A., Vance,R.E., Aderem,A. and Miao,E.A.
    Caspase-11 protects against bacteria that escape the vacuole
    Science339, 975-978. PubMed  Europe PubMed DOI
  64. Berghe,T.V., Goethals,A., Demon,D., Bogaert,P., Mak,T.W., Cauwels,A. and Vandenabeele,P.
    An inactivating caspase-11 passenger mutation muddles sepsis research
    Am J Respir Crit Care Med188, 120-121. PubMed  Europe PubMed DOI  M
  65. Bordon,Y.
    Innate immunity: Caspase 11 hunts down cytosolic bacteria
    Nat Rev Immunol13, 154-155. PubMed  Europe PubMed DOI
  66. Broz,P. and Monack,D.M.
    Noncanonical inflammasomes: caspase-11 activation and effector mechanisms
    PLoS Pathog9, e1003144-e1003144. PubMed  Europe PubMed DOI
  67. Case,C.L., Kohler,L.J., Lima,J.B., Strowig,T., de Zoete,M.R., Flavell,R.A., Zamboni,D.S. and Roy,C.R.
    Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila
    Proc Natl Acad Sci U S A110, 1851-1856. PubMed  Europe PubMed DOI
  68. Ng,T.M. and Monack,D.M.
    Revisiting caspase-11 function in host defense
    Cell Host Microbe14, 9-14. PubMed  Europe PubMed DOI
  69. Shin,S. and Brodsky,I.E.
    Caspase-11: the noncanonical guardian of cytosolic sanctity
    Cell Host Microbe13, 243-245. PubMed  Europe PubMed DOI
  70. Vigano,E. and Mortellaro,A.
    Caspase-11: the driving factor for noncanonical inflammasomes
    Eur J Immunol43, 2240-2245. PubMed  Europe PubMed DOI
    71. 2012
  71. Rickert,R.C., Salvesen,G.S. and Ware,C.F.
    Mousing around with caspases and IAPs
    Biochem J443, e1-e2. PubMed  Europe PubMed DOI
    72. 2011
  72. Dempsey,L.A.
    Caspase-11 inflammasomes
    Nat Immunol12, 1141-1141. DOI
  73. Kayagaki,N., Warming,S., Lamkanfi,M., Walle,L.V., Louie,S., Dong,J., Newton,K., Qu,Y., Liu,J., Heldens,S., Zhang,J., Lee,W.P., Roose-Girma,M. and Dixit,V.M.
    Non-canonical inflammasome activation targets caspase-11
    Nature479, 117-121. PubMed  Europe PubMed DOI  K
    74. 2010
  74. Fradejas,N., Pastor,M.D., Burgos,M., Beyaert,R., Tranque,P. and Calvo,S.
    Caspase-11 mediates ischemia-induced astrocyte death: Involvement of endoplasmic reticulum stress and C/EBP homologous protein
    J Neurosci Res88, 1094-1105. PubMed  Europe PubMed DOI
    75. 2008
  75. Kang,S.J.
    A possible physiological role of caspase-11 during germinal center reaction
    Animal Cells Syst12, 127-136.  K
  76. Lee,J.M., Kim,Y.J., Ra,H., Kang,S.J., Han,S., Koh,J.Y. and Kim,Y.H.
    The involvement of caspase-11 in TPEN-induced apoptosis
    FEBS Lett582, 1871-1876. PubMed  Europe PubMed DOI
    77. 2007
  77. Bailly,M.
    Moving away from death: when caspase-11 meets cofilin
    Nat Cell Biol9, 245-246. PubMed  Europe PubMed DOI
  78. Martinon,F. and Tschopp,J.
    Inflammatory caspases and inflammasomes: master switches of inflammation
    Cell Death Differ14, 10-22. PubMed  Europe PubMed DOI
    79. 2004
  79. [YEAR:21-9-2004]Arai,H., Furuya,T., Yasuda,T., Miura,M., Mizuno,Y. and Mochizuki,H.
    Neurotoxic effects of lipopolysaccharide on nigral dopaminergic neurons are mediated by microglial activation, interleukin-1beta, and expression of caspase-11 in mice
    J Biol Chem279, 51647-51653. PubMed  Europe PubMed DOI
    80. 2002
  80. Mueller,N.J., Wilkinson,R.A. and Fishman,J.A.
    Listeria monocytogenes infection in caspase-11-deficient mice
    Infect Immun70, 2657-2664. PubMed  Europe PubMed DOI  K
    81. 2000
  81. [YEAR:1-5-2000]Kang,S.J., Wang,S.Y., Hara,H., Peterson,E.P., Namura,S., Amin-Hanjani,S., Huang,Z.H., Srinivasan,A., Tomaselli,K.J., Thornberry,N.A., Moskowitz,M.A. and Yuan,J.Y.
    Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions
    J Cell Biol149, 613-622. PubMed  Europe PubMed DOI
    82. 1998
  82. [YEAR:20-2-1998]Wang,S., Miura,M., Jung,Y.K., Zhu,H., Li,E. and Yuan,J.
    Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
    Cell92, 501-509. PubMed  Europe PubMed DOI

feedback
Page created 8-September-2023

EMBL-EBI logo

© 2025 EBI
Terms of use