Literature for peptidase C14.012: caspase-11

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: M Mutation, P Specificity, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025

Eltobgy,M.M., Shamseldin,M.M., Whitham,O., Amer,H.M., Atkinson,J., Badr,A., Hall,J., Omran,J., Gupta,G., Hassan,Y., Abdelaleem,R., Perez,R., Faber,S., Pietrzak,M., Webb,A., Zhang,X., Kenney,A.D., Bissel,D., Estfanous,S., Daily,K., McNamara,A., Mahesh,K.C., Peeples,M.E., Hemann,E.A., Nimjee,S.M., Cormet-Boyaka,E., Li,J., Boyaka,P.N., Yount,J.S., Segal,B., Dubey,P. and Amer,A.O. Caspase-11 Mediated Hyperinflammation Impairs CD8(+) T Cell Immunity and Viral Clearance in Severe SARS-CoV-2 Infection bioRxiv (2025) PubMed Europe PubMed DOI PMC EPMC
Shi,Y., He,T., Liu,H., Li,X., Li,Z., Wen,Q., Dai,Z., Sun,X., Tan,Q., Yang,W., Jiang,Y., Liu,Y., Yuan,H., Lei,F., Yi,Y. and Cai,J. Ganglioside GA2-mediated caspase-11 activation drives macrophage pyroptosis aggravating intimal hyperplasia after arterial injury Int J Biol Sci (2025) 21, 433-453. PubMed Europe PubMed DOI PMC EPMC K

2024

Ai,Y., Meng,Y., Yan,B., Zhou,Q. and Wang,X. The biochemical pathways of apoptotic, necroptotic, pyroptotic, and ferroptotic cell death Mol Cell (2024) 84, 170-179. PubMed Europe PubMed DOI V
Akuma,D.C., Wodzanowski,K.A., Schwartz Wertman,R., Exconde,P.M., Vazquez Marrero,V.R., Odunze,C.E., Grubaugh,D., Shin,S., Taabazuing,C. and Brodsky,I.E. Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS elife (2024) 13 PubMed Europe PubMed DOI PMC EPMC
Daily,K.P., Badr,A., Eltobgy,M., Estfanous,S., Whitham,O., Tan,M.H., Carafice,C., Krause,K., McNamara,A., Hamilton,K., Houle,S., Gupta,S., Gupta,G.A., Madhu,S., Fitzgerald,J., Saadey,A.A., Laster,B., Yan,P., Webb,A., Zhang,X., Pietrzak,M., Kokiko-Cochran,O.N., Ghoneim,H.E. and Amer,A.O. DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-beta deposition in Alzheimer's disease Alzheimers Res Ther (2024) 16, 29-29. PubMed Europe PubMed DOI PMC EPMC
Eckhart,L. and Fischer,H. Caspase-5: Structure, Pro-Inflammatory Activity and Evolution Biomolecules (2024) 14 PubMed Europe PubMed DOI PMC EPMC V
Tan,J., Feng,L., Ragavan,N.D., Chai Theam,O. and Li,X. The promotive effect of Caspase-11 overexpression in a rat model of chronic kidney disease and the therapeutic efficacy of exosome-delivered siRNA in inhibiting Caspase-11 Biochem Biophys Res Commun (2024) 741, 151013-151013. PubMed Europe PubMed DOI
Wright,S.S., Wang,C., Ta,A., Havira,M.S., Ruan,J., Rathinam,V.A. and Vanaja,S.K. A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis Cell Rep (2024) 43, 114004-114004. PubMed Europe PubMed DOI

2023

Cho,H.J., Kim,E. and Yi,Y.S. Korean Red Ginseng Saponins Play an Anti-Inflammatory Role by Targeting Caspase-11 Non-Canonical Inflammasome in Macrophages Int J Mol Sci (2023) 24 PubMed Europe PubMed DOI PMC EPMC
Jiao,P., Li,Z., Li,B. and Jiao,X. The Role of Caspase-11 and Pyroptosis in the Regulation of Inflammation in Peri-Implantitis J Inflamm Res (2023) 16, 4471-4479. PubMed Europe PubMed DOI PMC EPMC
Karasawa,T., Komada,T., Baatarjav,C., Aizawa,E., Mizushina,Y., Fujimura,K., Gunji,Y., Komori,S., Aizawa,H., Jing Tao,C.B., Matsumura,T. and Takahashi,M. Caspase-11 deficiency attenuates neutrophil recruitment into the atherosclerotic lesion in apolipoprotein E-deficient mice Biochem Biophys Res Commun (2023) 686, 149158-149158. PubMed Europe PubMed DOI
Sahoo,G., Samal,D., Khandayataray,P. and Murthy,M.K. A Review on Caspases: Key Regulators of Biological Activities and Apoptosis Mol Neurobiol (2023) 60, 5805-5837. PubMed Europe PubMed DOI V
Shi,X., Sun,Q., Hou,Y., Zeng,H., Cao,Y., Dong,M., Ding,J. and Shao,F. Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome Nature (2023) 624, 442-450. PubMed Europe PubMed DOI
Yi,Y.S. Regulatory Roles of Flavonoids in Caspase-11 Non-Canonical Inflammasome-Mediated Inflammatory Responses and Diseases Int J Mol Sci (2023) 24 PubMed Europe PubMed DOI PMC EPMC V

2022

Eltobgy,M.M., Zani,A., Kenney,A.D., Estfanous,S., Kim,E., Badr,A., Carafice,C., Daily,K., Whitham,O., Pietrzak,M., Webb,A., Kawahara,J., Eddy,A.C., Denz,P., Lu,M., Kc,M., Peeples,M.E., Li,J., Zhu,J., Que,J., Robinson,R., Rosas Mejia,O., Rayner,R.E., Hall-Stoodley,L., Seveau,S., Gavrilin,M.A., Zhang,X., Thomas,J., Kohlmeier,J.E., Suthar,M.S., Oltz,E., Tedeschi,A., Robledo-Avila,F.H., Partida-Sanchez,S., Hemann,E.A., Abdelrazik,E., Forero,A., Nimjee,S.M., Boyaka,P.N., Cormet-Boyaka,E., Yount,J.S. and Amer,A.O. Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and immunothrombosis Proc Natl Acad Sci U S A (2022) 119, e2202012119-e2202012119. PubMed Europe PubMed DOI PMC EPMC
Hu,Y., Jiang,Y., Li,S., Ma,X., Chen,M., Yang,R., Wen,S., Moynagh,P.N., Wang,B., Hu,G. and Yang,S. The Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/11 Proc Natl Acad Sci U S A (2022) 119, e2210809119-e2210809119. PubMed Europe PubMed DOI PMC EPMC
Ross,C., Chan,A.H., von Pein,J.B., Maddugoda,M.P., Boucher,D. and Schroder,K. Inflammatory Caspases: Toward a Unified Model for Caspase Activation by Inflammasomes Annu Rev Immunol (2022) PubMed Europe PubMed DOI V
Smith,A.P. and Creagh,E.M. Caspase-4 and -5 Biology in the Pathogenesis of Inflammatory Bowel Disease Front Pharmacol (2022) 13, 919567-919567. PubMed Europe PubMed DOI PMC EPMC V
Tsutsuki,H., Zhang,T., Yahiro,K., Ono,K., Fujiwara,Y., Iyoda,S., Wei,F.Y., Monde,K., Seto,K., Ohnishi,M., Oshiumi,H., Akaike,T. and Sawa,T. Subtilase cytotoxin from Shiga-toxigenic Escherichia coli impairs the inflammasome and exacerbates enteropathogenic bacterial infection iScience (2022) 25, 104050-104050. PubMed Europe PubMed DOI PMC EPMC
Wang,Z., Chan,W. and Yue,Y. A significant other: Non-canonical caspase-4/5/11 inflammasome in periodontitis Oral Dis (2022) PubMed Europe PubMed DOI V
Yi,Y.S. Dual roles of the caspase-11 non-canonical inflammasome in inflammatory bowel disease Int Immunopharmacol (2022) 108, 108739-108739. PubMed Europe PubMed DOI V
Yi,Y.S. Regulatory Roles of Caspase-11 Non-Canonical Inflammasome in Inflammatory Liver Diseases Int J Mol Sci (2022) 23 PubMed Europe PubMed DOI PMC EPMC V
Yin,F., Zheng,P.Q., Zhao,L.Q., Wang,Y.Z., Miao,N.J., Zhou,Z.L., Cheng,Q., Chen,P.P., Xie,H.Y., Li,J.Y., Ni,J.Y., Zhou,L., Zhang,W., Wang,X.X., Liu,J. and Lu,L.M. Caspase-11 promotes NLRP3 inflammasome activation via the cleavage of pannexin1 in acute kidney disease Acta Pharmacol Sin (2022) 43, 86-95. PubMed Europe PubMed DOI K

2021

Agnew,A., Nulty,C. and Creagh,E.M. Regulation, Activation and Function of Caspase-11 during Health and Disease Int J Mol Sci (2021) 22 PubMed Europe PubMed DOI PMC EPMC V
Bateman,G., Hill,B., Knight,R. and Boucher,D. Great balls of fire: activation and signalling of inflammatory caspases Biochem Soc Trans (2021) 49, 1311-1324. PubMed Europe PubMed DOI V
Biasizzo,M., Trstenjak-Prebanda,M., Dolinar,K., Pirkmajer,S., Zavrsnik,J., Turk,B. and Kopitar-Jerala,N. Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice Cells (2021) 10 PubMed Europe PubMed DOI PMC EPMC
Li,Z., Liu,W., Fu,J., Cheng,S., Xu,Y., Wang,Z., Liu,X., Shi,X., Liu,Y., Qi,X., Liu,X., Ding,J. and Shao,F. Shigella evades pyroptosis by arginine ADP-riboxanation of caspase-11 Nature (2021) 599, 290-295. PubMed Europe PubMed DOI
Lima,C., Falcao,M.A.P., Andrade-Barros,A.I., Seni-Silva,A.C., Grund,L.Z., Balogh,E., Conceicao,K., Queniaux,V.F., Ryffel,B. and Lopes-Ferreira,M. Natterin an aerolysin-like fish toxin drives IL-1beta-dependent neutrophilic inflammation mediated by caspase-1 and caspase-11 activated by the inflammasome sensor NLRP6 Int Immunopharmacol (2021) 91, 107287-107287. PubMed Europe PubMed DOI
Wu,J., Sun,J. and Meng,X. Pyroptosis by caspase-11 inflammasome-Gadermin D pathway in autoimmune diseases Pharmacol Res (2021) , 105408-105408. PubMed Europe PubMed DOI V
Wu,M., Shi,J., He,S., Wang,D., Zhang,N., Wang,Z., Yang,F., He,J., Hu,D., Yang,X. and Yuan,C. cGAS promotes sepsis in radiotherapy of cancer by up-regulating caspase-11 signaling Biochem Biophys Res Commun (2021) 551, 86-92. PubMed Europe PubMed DOI
Yi,Y.S. Caspase-11 Noncanonical Inflammasome: A Novel Key Player in Murine Models of Neuroinflammation and Multiple Sclerosis Neuroimmunomodulation (2021) , 1-9. PubMed Europe PubMed DOI V
Zheng,M., Karki,R., Kancharana,B., Berns,H., Pruett-Miller,S.M. and Kanneganti,T.D. Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections J Biol Chem (2021) 297, 101379-101379. PubMed Europe PubMed DOI PMC EPMC

2020

Abu Khweek,A. and Amer,A.O. Pyroptotic and non-pyroptotic effector functions of caspase-11 Immunol Rev (2020) , e12910-e12910. PubMed Europe PubMed DOI
Bibo-Verdugo,B., Snipas,S.J., Kolt,S., Poreba,M. and Salvesen,G.S. Extended subsite profiling of the pyroptosis effector protein gasdermin D reveals a region recognized by inflammatory caspase-11 J Biol Chem (2020) PubMed Europe PubMed DOI
Chao,L., Li,Z., Zhou,J., Chen,W., Li,Y., Lv,W., Guo,A., Qu,Q. and Guo,S. Shen-Ling-Bai-Zhu-San Improves Dextran Sodium Sulfate-Induced Colitis by Inhibiting Caspase-1/Caspase-11-Mediated Pyroptosis Front Pharmacol (2020) 11, 814-814. PubMed Europe PubMed DOI PMC EPMC
Fagenson,A.M., Xu,K., Saaoud,F., Nanayakkara,G., Jhala,N.C., Liu,L., Drummer,C., Sun,Y., Lau,K.N., Di Carlo,A., Jiang,X., Wang,H., Karhadkar,S.S. and Yang,X. Liver Ischemia Reperfusion Injury, Enhanced by Trained Immunity, Is Attenuated in Caspase 1/Caspase 11 Double Gene Knockout Mice Pathogens (2020) 9 PubMed Europe PubMed DOI
Kovacs,S.B., Oh,C., Maltez,V.I., McGlaughon,B.D., Verma,A., Miao,E.A. and Aachoui,Y. Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium Cell Rep (2020) 32, 107967-107967. PubMed Europe PubMed DOI
Peng,Y., Gao,M., Liu,Y., Qiu,X., Cheng,X., Yang,X., Chen,F. and Wang,E. Bacterial outer membrane vesicles induce disseminated intravascular coagulation through the caspase-11-gasdermin D pathway Thromb Res (2020) 196, 159-166. PubMed Europe PubMed DOI
Sachdev,U., Ferrari,R., Cui,X., Pius,A., Sahu,A., Reynolds,M., Liao,H., Sun,P., Shinde,S., Ambrosio,F., Shiva,S., Loughran,P. and Scott,M. Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine Mol Med (2020) 26, 69-69. PubMed Europe PubMed DOI PMC EPMC K
Sakaguchi,N., Sasai,M., Bando,H., Lee,Y., Pradipta,A., Ma,J.S. and Yamamoto,M. Role of Gate-16 and Gabarap in Prevention of Caspase-11-Dependent Excess Inflammation and Lethal Endotoxic Shock Front Immunol (2020) 11, 561948-561948. PubMed Europe PubMed DOI PMC EPMC
Thorstenberg,M.L., Martins,M.D.A., Figliuolo,V., Silva,C.L.M., Savio,L.E.B. and Coutinho-Silva,R. P2Y2 Receptor Induces L. amazonensis Infection Control in a Mechanism Dependent on Caspase-1 Activation and IL-1beta Secretion Mediators Inflamm (2020) 2020, 2545682-2545682. PubMed Europe PubMed DOI PMC EPMC
Wang,X., Liu,Z. and Shen,L. [Isoflurane preconditioning inhibits caspase-11-related noncanonical pyroptosis pathway to alleviate hepatic ischemia-reperfusion injury in mice] Nan Fang Yi Ke Da Xue Xue Bao (2020) 40, 670-675. PubMed Europe PubMed DOI PMC EPMC
Wang,Y., Zhang,M., Sun,Y., Wang,X., Song,Z., Li,H., Liu,K. and Li,Z. Role of short-wavelength blue light in the formation of cataracts and the expression of caspase-1, caspase-11, Gasdermin D in rat lens epithelial cells: insights into a novel pathogenic mmechanism of cataracts BMC Ophthalmol (2020) 20, 289-289. PubMed Europe PubMed DOI PMC EPMC I
Yi,Y.S. Caspase-11 non-canonical inflammasome: emerging activator and regulator of infection-mediated inflammatory responses Int J Mol Sci (2020) 21 PubMed Europe PubMed DOI
Zaslona,Z., Flis,E., Nulty,C., Kearney,J., FitzGerald,R., Douglas,A.R., McNamara,D., Smith,S., O'Neill,L.A.J. and Creagh,E.M. Caspase-4: A Therapeutic Target for Peptic Ulcer Disease Immunohorizons (2020) 4, 627-633. PubMed Europe PubMed DOI

2019

Huang,X., Feng,Y., Xiong,G., Whyte,S., Duan,J., Yang,Y., Wang,K., Yang,S., Geng,Y., Ou,Y. and Chen,D. Caspase-11, a specific sensor for intracellular lipopolysaccharide recognition, mediates the non-canonical inflammatory pathway of pyroptosis Cell Biosci (2019) 9, 31-31. PubMed Europe PubMed DOI PMC EPMC
Lu,Y., Meng,R., Wang,X., Xu,Y., Tang,Y., Wu,J., Xue,Q., Yu,S., Duan,M., Shan,D., Wang,Q., Wang,H., Billiar,T.R., Xiao,X., Chen,F. and Lu,B. Caspase-11 signaling enhances graft-versus-host disease Nat Commun (2019) 10, 4044-4044. PubMed Europe PubMed DOI PMC EPMC

2018

Baker,P.J. and Masters,S.L. Caspase substrates won't be defined by a four-letter code J Biol Chem (2018) 293, 7068-7069. PubMed Europe PubMed DOI PMC EPMC P
Chen,N., Ou,Z., Zhang,W., Zhu,X., Li,P. and Gong,J. Cathepsin B regulates non-canonical NLRP3 inflammasome pathway by modulating activation of caspase-11 in Kupffer cells Cell Prolif (2018) , e12487-e12487. PubMed Europe PubMed DOI
Lee,B.L., Stowe,I.B., Gupta,A., Kornfeld,O.S., Roose-Girma,M., Anderson,K., Warming,S., Zhang,J., Lee,W.P. and Kayagaki,N. Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation J Exp Med (2018) 215, 2279-2288. PubMed Europe PubMed DOI
Ramirez,M.L.G., Poreba,M., Snipas,S.J., Groborz,K., Drag,M. and Salvesen,G.S. Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1 J Biol Chem (2018) 293, 7058-7067. PubMed Europe PubMed DOI P
Ross,C., Chan,A.H., Von Pein,J., Boucher,D. and Schroder,K. Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome Life Sci Alliance (2018) 1, e201800237-e201800237. PubMed Europe PubMed DOI PMC EPMC
Tang,Y., Zhang,R., Xue,Q., Meng,R., Wang,X., Yang,Y., Xie,L., Xiao,X., Billiar,T.R. and Lu,B. TRIF signaling is required for caspase-11-dependent immune responses and lethality in sepsis Mol Med (2018) 24, 66-66. PubMed Europe PubMed DOI
Yi,Y.S. Regulatory roles of the caspase-11 non-canonical inflammasome in inflammatory diseases Immune Netw (2018) 18, e41-e41. PubMed Europe PubMed DOI PMC EPMC

2015

Caution,K., Gavrilin,M.A., Tazi,M., Kanneganti,A., Layman,D., Hoque,S., Krause,K. and Amer,A.O. Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance Sci Rep (2015) 5, 18479-18479. PubMed Europe PubMed DOI PMC EPMC
Cerqueira,D.M., Pereira,M.S., Silva,A.L., Cunha,L.D. and Zamboni,D.S. Caspase-1 but not caspase-11 is required for NLRC4-mediated pyroptosis and restriction of infection by flagellated Legionella species in mouse macrophages and in vivo J Immunol (2015) 195, 2303-2311. PubMed Europe PubMed DOI
de Gassart,A. and Martinon,F. Pyroptosis: caspase-11 unlocks the gates of death Immunity (2015) 43, 835-837. PubMed Europe PubMed DOI
Hendrikx,T., Jeurissen,M.L., van Gorp,P.J., Gijbels,M.J., Walenbergh,S.M., Houben,T., van Gorp,R., Pottgens,C.C., Stienstra,R., Netea,M.G., Hofker,M.H., Donners,M.M. and Shiri-Sverdlov,R. Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr(-/-) mice FEBS J (2015) 282, 2327-2338. PubMed Europe PubMed DOI K
Huang,W., Xie,W.B., Qiao,D., Qiu,P., Huang,E., Li,B., Chen,C., Liu,C., Wang,Q., Lin,Z. and Wang,H. Caspase-11 plays an essential role in methamphetamine-induced dopaminergic neuron apoptosis Toxicol Sci (2015) 145, 68-79. PubMed Europe PubMed DOI
Kayagaki,N., Stowe,I.B., Lee,B.L., O'Rourke,K., Anderson,K., Warming,S., Cuellar,T., Haley,B., Roose-Girma,M., Phung,Q.T., Liu,P.S., Lill,J.R., Li,H., Wu,J., Kummerfeld,S., Zhang,J., Lee,W.P., Snipas,S.J., Salvesen,G.S., Morris,L.X., Fitzgerald,L., Zhang,Y., Bertram,E.M., Goodnow,C.C. and Dixit,V.M. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling Nature (2015) 526, 666-671. PubMed Europe PubMed DOI
Shi,J., Zhao,Y., Wang,K., Shi,X., Wang,Y., Huang,H., Zhuang,Y., Cai,T., Wang,F. and Shao,F. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death Nature (2015) 526, 660-665. PubMed Europe PubMed DOI

2014

Knodler,L.A., Crowley,S.M., Sham,H.P., Yang,H., Wrande,M., Ma,C., Ernst,R.K., Steele-Mortimer,O., Celli,J. and Vallance,B.A. Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens Cell Host Microbe (2014) 16, 249-256. PubMed Europe PubMed DOI
Py,B.F., Jin,M., Desai,B.N., Penumaka,A., Zhu,H., Kober,M., Dietrich,A., Lipinski,M.M., Henry,T., Clapham,D.E. and Yuan,J. Caspase-11 controls interleukin-1beta release through degradation of TRPC1 Cell Rep (2014) 6, 1122-1128. PubMed Europe PubMed DOI

2013

Aachoui,Y., Leaf,I.A., Hagar,J.A., Fontana,M.F., Campos,C.G., Zak,D.E., Tan,M.H., Cotter,P.A., Vance,R.E., Aderem,A. and Miao,E.A. Caspase-11 protects against bacteria that escape the vacuole Science (2013) 339, 975-978. PubMed Europe PubMed DOI
Berghe,T.V., Goethals,A., Demon,D., Bogaert,P., Mak,T.W., Cauwels,A. and Vandenabeele,P. An inactivating caspase-11 passenger mutation muddles sepsis research Am J Respir Crit Care Med (2013) 188, 120-121. PubMed Europe PubMed DOI M
Bordon,Y. Innate immunity: Caspase 11 hunts down cytosolic bacteria Nat Rev Immunol (2013) 13, 154-155. PubMed Europe PubMed DOI
Broz,P. and Monack,D.M. Noncanonical inflammasomes: caspase-11 activation and effector mechanisms PLoS Pathog (2013) 9, e1003144-e1003144. PubMed Europe PubMed DOI PMC EPMC
Case,C.L., Kohler,L.J., Lima,J.B., Strowig,T., de Zoete,M.R., Flavell,R.A., Zamboni,D.S. and Roy,C.R. Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila Proc Natl Acad Sci U S A (2013) 110, 1851-1856. PubMed Europe PubMed DOI
Ng,T.M. and Monack,D.M. Revisiting caspase-11 function in host defense Cell Host Microbe (2013) 14, 9-14. PubMed Europe PubMed DOI
Shin,S. and Brodsky,I.E. Caspase-11: the noncanonical guardian of cytosolic sanctity Cell Host Microbe (2013) 13, 243-245. PubMed Europe PubMed DOI
Vigano,E. and Mortellaro,A. Caspase-11: the driving factor for noncanonical inflammasomes Eur J Immunol (2013) 43, 2240-2245. PubMed Europe PubMed DOI

2012

Rickert,R.C., Salvesen,G.S. and Ware,C.F. Mousing around with caspases and IAPs Biochem J (2012) 443, e1-e2. PubMed Europe PubMed DOI

2011

Dempsey,L.A. Caspase-11 inflammasomes Nat Immunol (2011) 12, 1141-1141. DOI
Kayagaki,N., Warming,S., Lamkanfi,M., Walle,L.V., Louie,S., Dong,J., Newton,K., Qu,Y., Liu,J., Heldens,S., Zhang,J., Lee,W.P., Roose-Girma,M. and Dixit,V.M. Non-canonical inflammasome activation targets caspase-11 Nature (2011) 479, 117-121. PubMed Europe PubMed DOI K

2010

Fradejas,N., Pastor,M.D., Burgos,M., Beyaert,R., Tranque,P. and Calvo,S. Caspase-11 mediates ischemia-induced astrocyte death: Involvement of endoplasmic reticulum stress and C/EBP homologous protein J Neurosci Res (2010) 88, 1094-1105. PubMed Europe PubMed DOI

2008

Kang,S.J. A possible physiological role of caspase-11 during germinal center reaction Animal Cells Syst (2008) 12, 127-136. K
Lee,J.M., Kim,Y.J., Ra,H., Kang,S.J., Han,S., Koh,J.Y. and Kim,Y.H. The involvement of caspase-11 in TPEN-induced apoptosis FEBS Lett (2008) 582, 1871-1876. PubMed Europe PubMed DOI

2007

Bailly,M. Moving away from death: when caspase-11 meets cofilin Nat Cell Biol (2007) 9, 245-246. PubMed Europe PubMed DOI
Martinon,F. and Tschopp,J. Inflammatory caspases and inflammasomes: master switches of inflammation Cell Death Differ (2007) 14, 10-22. PubMed Europe PubMed DOI

2004

[YEAR:21-9-2004]Arai,H., Furuya,T., Yasuda,T., Miura,M., Mizuno,Y. and Mochizuki,H. Neurotoxic effects of lipopolysaccharide on nigral dopaminergic neurons are mediated by microglial activation, interleukin-1beta, and expression of caspase-11 in mice J Biol Chem (21-9-2004) 279, 51647-51653. PubMed Europe PubMed DOI

2002

Mueller,N.J., Wilkinson,R.A. and Fishman,J.A. Listeria monocytogenes infection in caspase-11-deficient mice Infect Immun (2002) 70, 2657-2664. PubMed Europe PubMed DOI PMC EPMC K

2000

[YEAR:1-5-2000]Kang,S.J., Wang,S.Y., Hara,H., Peterson,E.P., Namura,S., Amin-Hanjani,S., Huang,Z.H., Srinivasan,A., Tomaselli,K.J., Thornberry,N.A., Moskowitz,M.A. and Yuan,J.Y. Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions J Cell Biol (1-5-2000) 149, 613-622. PubMed Europe PubMed DOI PMC EPMC

1998

[YEAR:20-2-1998]Wang,S., Miura,M., Jung,Y.K., Zhu,H., Li,E. and Yuan,J. Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE Cell (20-2-1998) 92, 501-509. PubMed Europe PubMed DOI