Literature for peptidase C01.062: cathepsin B-like peptidase (platyhelminth)

(Topics flags: S Structure, K Knockout, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2024
1. Fuchs,N., Zimmermann,R.A., Schwickert,M., Gunkel,A., Zimmer,C., Meta,M., Schwickert,K., Keiser,J., Haeberli,C., Kiefer,W. and Schirmeister,T.
   Dual Strategy to Design New Agents Targeting Schistosoma mansoni: Advancing Phenotypic and SmCB1 Inhibitors for Improved Efficacy
   ACS Infect Dis10, 1664-1678. PubMed  Europe PubMed DOI  I
2. Nascimento,I., Albino,S., Menezes,K., Cavalcanti,M., Oliveira,M., Mali,S. and Moura,R.
   Targeting SmCB1: Perspectives and Insights to Design Antischistosomal Drugs
   Curr Med Chem31, 2264-2284. PubMed  Europe PubMed DOI
3. Spiwokova,P., Horn,M., Fanfrlik,J., Jilkova,A., Fajtova,P., Leontovyc,A., Houstecka,R., Bielikova,L., Brynda,J., Chanova,M., Mertlikova-Kaiserova,H., Caro-Diaz,E.J.E., Almaliti,J., El-Sakkary,N., Gerwick,W.H., Caffrey,C.R. and Mares,M.
   Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis
   ACS Infect Dis10, 1935-1948. PubMed  Europe PubMed DOI  I
2022
4. Perera,D.J., Hassan,A.S., Liu,S.S., Elahi,S.M., Gadoury,C., Weeratna,R.D., Gilbert,R. and Ndao,M.
   A low dose adenovirus vectored vaccine expressing Schistosoma mansoni Cathepsin B protects from intestinal schistosomiasis in mice
   EBioMedicine80, 104036-104036. PubMed  Europe PubMed DOI
2020
5. Dvorakova,H., Leontovyc,R., Machacek,T., O'Donoghue,A.J., Sedo,O., Zdrahal,Z., Craik,C.S., Caffrey,C.R., Horak,P. and Mikes,L.
   Isoforms of cathepsin B1 in neurotropic schistosomula of Trichobilharzia regenti differ in substrate preferences and a highly expressed catalytically inactive paralog binds cystatin
   Front Cell Infect Microbiol10, 66-66. PubMed  Europe PubMed DOI  P
6. Jilkova,A., Horn,M. and Mares,M.
   Structural and functional characterization of Schistosoma mansoni cathepsin B1
   Methods Mol Biol2151, 145-158. PubMed  Europe PubMed DOI  E  S  I
7. Jilkova,A., Horn,M., Fanfrlik,J., Kuppers,J., Pachl,P., Rezacova,P., Lepsik,M., Fajtova,P., Rubesova,P., Chanova,M., Caffrey,C.R., Gutschow,M. and Mares,M.
   Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to Schistosoma mansoni: Structural and Mechanistic Insights into Chemotype Reactivity
   ACS Infect Dis PubMed  Europe PubMed DOI
8. Jilkova,A., Rubesova,P., Fanfrlik,J., Fajtova,P., Rezacova,P., Brynda,J., Lepsik,M., Mertlikova-Kaiserova,H., Emal,C.D., Renslo,A.R., Roush,W.R., Horn,M., Caffrey,C.R. and Mares,M.
   Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors
   ACS Infect Dis PubMed  Europe PubMed DOI
9. Kianifard,L., Yakhchali,M. and Imani,M.
   The Effects of pH and Temperature on Cysteine Protease (Cathepsin B) Activity in Miracidia and Eggs of Fasciola hepatica
   Iran J Parasitol15, 233-239. PubMed  Europe PubMed
10. Perera,D.J., Hassan,A.S., Jia,Y., Ricciardi,A., McCluskie,M.J., Weeratna,R.D. and Ndao,M.
    Adjuvanted Schistosoma mansoni-Cathepsin B With Sulfated Lactosyl Archaeol Archaeosomes or AddaVax Provides Protection in a Pre-Clinical Schistosomiasis Model
    Front Immunol11, 605288-605288. PubMed  Europe PubMed DOI
11. Tallima,H., Abou El Dahab,M. and El Ridi,R.
    Specific Antibodies and Arachidonic Acid Mediate the Protection Induced by the Schistosoma mansoni Cysteine Peptidase-Based Vaccine in Mice
    Vaccines (Basel)8, PubMed  Europe PubMed DOI
2019
12. Soloviova,K., Fox,E.C., Dalton,J.P., Caffrey,C.R. and Davies,S.J.
    A secreted schistosome cathepsin B1 cysteine protease and acute schistosome infection induce a transient T helper 17 response
    PLoS Negl Trop Dis13, e0007070-e0007070. PubMed  Europe PubMed DOI
2015
13. Chen,W., Ning,D., Wang,X., Chen,T., Lv,X., Sun,J., Wu,D., Huang,Y., Xu,J. and Yu,X.
    Identification and characterization of Clonorchis sinensis cathepsin B proteases in the pathogenesis of clonorchiasis
    Parasit Vectors8, 647-647. PubMed  Europe PubMed DOI
14. Fonseca,N.C., da Cruz,L.F., da Silva Villela,F., do Nascimento Pereira,G.A., de Siqueira-Neto,J.L., Kellar,D., Suzuki,B.M., Ray,D., de Souza,T.B., Alves,R.J., Junior,P.A., Romanha,A.J., Murta,S.M., McKerrow,J.H., Caffrey,C.R., de Oliveira,R.B. and Ferreira,R.S.
    Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1
    Antimicrob Agents Chemother59, 2666-2677. PubMed  Europe PubMed DOI  I
15. Ricciardi,A., Dalton,J.P. and Ndao,M.
    Evaluation of the immune response and protective efficacy of Schistosoma mansoni cathepsin B in mice using CpG dinucleotides as adjuvant
    Vaccine33, 346-353. PubMed  Europe PubMed DOI
16. Siricoon,S., Vichasri Grams,S., Lertwongvisarn,K., Abdullohfakeeyah,M., Smooker,P.M. and Grams,R.
    Fasciola gigantica cathepsin B5 is an acidic endo- and exopeptidase of the immature and mature parasite
    Biochimie119, 6-15. PubMed  Europe PubMed DOI
2014
17. Chen,W., Wang,X., Lv,X., Tian,Y., Xu,Y., Mao,Q., Shang,M., Li,X., Huang,Y. and Yu,X.
    Characterization of the secreted cathepsin B cysteine proteases family of the carcinogenic liver fluke Clonorchis sinensis
    Parasitol Res113, 3409-3418. PubMed  Europe PubMed DOI
18. Dalton,J.P. and Dvorak,J.
    Activating the cathepsin B1 of a parasite: a major route with alternative pathways?
    Structure22, 1696-1698. PubMed  Europe PubMed DOI  S
19. El Ridi,R., Tallima,H., Dalton,J.P. and Donnelly,S.
    Induction of protective immune responses against schistosomiasis using functionally active cysteine peptidases
    Front Genet5, 119-119. PubMed  Europe PubMed DOI
20. Jilkova,A., Horn,M., Rezacova,P., Maresova,L., Fajtova,P., Brynda,J., Vondrasek,J., McKerrow,J.H., Caffrey,C.R. and Mares,M.
    Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch
    Structure22, 1786-1798. PubMed  Europe PubMed DOI  S
2013
21. Fanfrlik,J., Brahmkshatriya,P.S., Rezac,J., Jilkova,A., Horn,M., Mares,M., Hobza,P. and Lepsik,M.
    Quantum mechanics-based scoring rationalizes the irreversible inactivation of parasitic Schistosoma mansoni cysteine peptidase by vinyl sulfone inhibitors
    J Phys Chem B117, 14973-14982. PubMed  Europe PubMed DOI  I
2012
22. Robinson,M.W., Brindley,P.J., McKerrow,J.H. and Dalton,J.P.
    Trematode cysteine endopeptidases
    [ISSN:978-0-12-407743-0]3, 1941-1949. DOI
23. Sripa,J., Brindley,P.J., Sripa,B., Loukas,A., Kaewkes,S. and Laha,T.
    Evaluation of liver fluke recombinant cathepsin B-1 protease as a serodiagnostic antigen for human opisthorchiasis
    Parasitol Int61, 191-195. PubMed  Europe PubMed DOI
2011
24. Horn,M., Jilkova,A., Vondrasek,J., Maresova,L., Caffrey,C.R. and Mares,M.
    Mapping the pro-peptide of the Schistosoma mansoni cathepsin B1 drug target: modulation of inhibition by heparin and design of mimetic inhibitors
    ACS Chem Biol6, 609-617. PubMed  Europe PubMed DOI
25. Kasny,M., Mikes,L., Doleckova,K., Hampl,V., Dvorak,J., Novotny,M. and Horak,P.
    Cathepsins B1 and B2 of Trichobilharzia spp., bird schistosomes causing cercarial dermatitis
    Adv Exp Med Biol712, 136-154. PubMed  Europe PubMed DOI
26. Sripa,J., Pinlaor,P., Brindley,P.J., Sripa,B., Kaewkes,S., Robinson,M.W., Young,N.D., Gasser,R.B., Loukas,A. and Laha,T.
    RNA interference targeting cathepsin B of the carcinogenic liver fluke, Opisthorchis viverrini
    Parasitol Int60, 283-288. PubMed  Europe PubMed DOI  K
2010
27. Donnelly,S., O'Neill,S.M., Stack,C.M., Robinson,M.W., Turnbull,L., Whitchurch,C. and Dalton,J.P.
    Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3
    J Biol Chem285, 3383-3392. PubMed  Europe PubMed DOI
28. Sripa,J., Laha,T., To,J., Brindley,P.J., Sripa,B., Kaewkes,S., Dalton,J.P. and Robinson,M.W.
    Secreted cysteine proteases of the carcinogenic liver fluke, Opisthorchis viverrini: regulation of cathepsin F activation by autocatalysis and trans-processing by cathepsin B
    Cell Microbiol12, 781-795. PubMed  Europe PubMed DOI
29. Tchoubrieva,E.B., Ong,P.C., Pike,R.N., Brindley,P.J. and Kalinna,B.H.
    Vector-based RNA interference of cathepsin B1 in Schistosoma mansoni
    Cell Mol Life Sci67, 3739-3748. PubMed  Europe PubMed DOI  K
2009
30. Doleckova,K., Kasny,M., Mikes,L., Cartwright,J., Jedelsky,P., Schneider,E.L., Dvorak,J., Mountford,A.P., Craik,C.S. and Horak,P.
    The functional expression and characterisation of a cysteine peptidase from the invasive stage of the neuropathogenic schistosome Trichobilharzia regenti
    Int J Parasitol39, 201-211. PubMed  Europe PubMed DOI
2008
31. Kaewpitoon,N., Laha,T., Kaewkes,S., Yongvanit,P., Brindley,P.J., Loukas,A. and Sripa,B.
    Characterization of cysteine proteases from the carcinogenic liver fluke, Opisthorchis viverrini
    Parasitol Res102, 757-764. PubMed  Europe PubMed DOI
32. Krautz-Peterson,G. and Skelly,P.J.
    Schistosome asparaginyl endopeptidase (legumain) is not essential for cathepsin B1 activation in vivo
    Mol Biochem Parasitol159, 54-58. PubMed  Europe PubMed DOI
2006
33. [YEAR:6-3-2006]Choe,Y., Leonetti,F., Greenbaum,D.C., Lecaille,F., Bogyo,M., Bromme,D., Ellman,J.A. and Craik,C.S.
    Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities
    J Biol Chem281, 12824-12832. PubMed  Europe PubMed DOI  P
2005
34. [YEAR:30-7-2005]Correnti,J.M., Brindley,P.J. and Pearce,E.J.
    Long-term suppression of cathepsin B levels by RNA interference retards schistosome growth
    Mol Biochem Parasitol143, 209-215. PubMed  Europe PubMed DOI
35. [YEAR:8-6-2005]Dvorak,J., Delcroix,M., Rossi,A., Vopalensky,V., Pospisek,M., Sedinova,M., Mikes,L., Sajid,M., Sali,A., McKerrow,J.H., Horak,P. and Caffrey,C.R.
    Multiple cathepsin B isoforms in schistosomula of Trichobilharzia regenti: identification, characterisation and putative role in migration and nutrition
    Int J Parasitol35, 895-910. PubMed  Europe PubMed DOI
36. Stack,C.M., Dalton,J.P., Cunneen,M. and Donnelly,S.
    De-glycosylation of Pichia pastoris-produced Schistosoma mansoni cathepsin B eliminates non-specific reactivity with IgG in normal human serum
    J Immunol Methods304, 151-157. PubMed  Europe PubMed DOI
2004
37. Dalton,J.P., McKerrow,J.H. and Brindley,P.J.
    Trematode cysteine endopeptidases
    [ISSN:0-12-079610-4]2, 1176-1182.  V
2003
38. Sajid,M., McKerrow,J.H., Hansell,E., Mathieu,M.A., Lucas,K.D., Hsieh,I., Greenbaum,D., Bogyo,M., Salter,J.P., Lim,K.C., Franklin,C., Kim,J.H. and Caffrey,C.R.
    Functional expression and characterization of Schistosoma mansoni cathepsin B and its trans-activation by an endogenous asparaginyl endopeptidase
    Mol Biochem Parasitol131, 65-75. PubMed  Europe PubMed DOI
2002
39. Sajid,M. and McKerrow,J.H.
    Cysteine proteases of parasitic organisms
    Mol Biochem Parasitol120, 1-21. PubMed  Europe PubMed
2001
40. Noya,O., De Noya,B.A., Ballen,D.E., Bermudez,H., Bout,D. and Hoebeke,J.
    Immunogenicity of synthetic peptides from the Sm31 antigen (cathepsin B) of the Schistosoma mansoni adult worms
    Parasite Immunol23, 567-573. PubMed  Europe PubMed DOI
41. Skelly,P.J. and Shoemaker,C.B.
    Schistosoma mansoni proteases Sm31 (cathepsin B) and Sm32 (legumain) are expressed in the cecum and protonephridia of cercariae
    J Parasitol87, 1218-1221. PubMed  Europe PubMed DOI
1998
42. Choi,M.H., Chai,J.Y. and Lee,S.H.
    Purification and characterization of a 16-kDa cysteine proteinase of Gymnophalloides seoi (Gymnophallidae) metacercariae
    J Parasitol84, 350-355. PubMed  Europe PubMed DOI
43. El-Sayed,L.H., Ghoneim,H., Demian,S.R., El-Sayed,M.H., Tawfik,N.M., Sakr,I., Abou-Basha,L.M., Renganathan,E., Klinkert,M.Q. and Abou-Rawash,N.
    Diagnostic significance of Schistosoma mansoni proteins Sm31 and Sm32 in human schistosomiasis in an endemic area in Egypt
    Trop Med Int Health3, 721-727. PubMed  Europe PubMed DOI
1997
44. Caffrey,C.R., Rheinberg,C.E., Mone,H., Jourdane,J., Li,Y.L. and Ruppel,A.
    Schistosoma japonicum, S. mansoni, S. haematobium, S. intercalatum, and S. rodhaini: cysteine-class cathepsin activities in the vomitus of adult worms
    Parasitol Res83, 37-41. PubMed  Europe PubMed
45. Caffrey,C.R. and Ruppel,A.
    Cathepsin B-like activity predominates over cathepsin L-like activity in adult Schistosoma mansoni and S. japonicum
    Parasitol Res83, 632-635. PubMed  Europe PubMed DOI
46. Dalton,J.P., Clough,K.A., Jones,M.K. and Brindley,P.J.
    The cysteine proteinases of Schistosoma mansoni cercariae
    Parasitology114, 105-112. PubMed  Europe PubMed DOI
47. Grogan,J., Rotmans,P., Ghoneim,H., Deelder,A., Yazdanbakhsh,M. and Klinkert,M.Q.
    Recognition of Schistosoma mansoni cathepsins B and L by human IgG1 and IgG4 antibodies
    Parasite Immunol19, 215-220. PubMed  Europe PubMed
1996
48. Dalton,J.P., Clough,K.A., Jones,M.K. and Brindley,P.J.
    Characterization of the cathepsin-like cysteine proteinases of Schistosoma mansoni
    Infect Immun64, 1328-1334. PubMed  Europe PubMed
49. Li,Y.L., Idris,M.A., Corachan,M., Han,J.J., Kirschfink,M. and Ruppel,A.
    Circulating antigens in schistosomiasis: detection of 31/32-kDa proteins in sera from patients infected with Schistosoma japonicum, S. mansoni, S. haematobium, or S. intercalatum
    Parasitol Res82, 14-18. PubMed  Europe PubMed DOI
50. Lipps,G., Fullkrug,R. and Beck,E.
    Cathepsin B of Schistosoma mansoni. Purification and activation of the recombinant proenzyme secreted by Saccharomyces cerevisiae
    J Biol Chem271, 1717-1725. PubMed  Europe PubMed
1995
51. Ghoneim,H. and Klinkert,M.Q.
    Biochemical properties of purified cathepsin B from Schistosoma mansoni
    Int J Parasitol25, 1515-1519. PubMed  Europe PubMed DOI
1993
52. Yamasaki,H. and Aoki,T.
    Cloning and sequence analysis of the major cysteine protease expressed in the trematode parasite Fasciola sp
    Biochem Mol Biol Int31, 537-542. PubMed  Europe PubMed
53. Yoshino,T.P., Lodes,M.J., Rege,A.A. and Chappell,C.L.
    Proteinase activity in miracidia, transformation excretory-secretory products, and primary sporocysts of Schistosoma mansoni
    J Parasitol79, 23-31. PubMed  Europe PubMed
1992
54. Gotz,B., Felleisen,R., Shaw,E. and Klinkert,M.Q.
    Expression of an active cathepsin B-like protein Sm31 from Schistosoma mansoni in insect cells
    Trop Med Parasitol43, 282-284. PubMed  Europe PubMed
1989
55. Klinkert,M.Q., Felleisen,R., Link,G., Ruppel,A. and Beck,E.
    Primary structures of Sm31/32 diagnostic proteins of Schistosoma mansoni and their identification as proteases
    Mol Biochem Parasitol33, 113-122. PubMed  Europe PubMed
1988
56. Zerda,K.S., Dresden,M.H. and Chappell,C.L.
    Schistosoma mansoni: expression and role of cysteine proteinases in developing schistosomula
    Exp Parasitol67, 238-246. PubMed  Europe PubMed
1987
57. Ruppel,A., Shi,Y.E., Wei,D.X. and Diesfeld,H.J.
    Sera of Schistosoma japonicum-infected patients cross-react with diagnostic 31/32 kD proteins of S. mansoni
    Clin Exp Immunol69, 291-298. PubMed  Europe PubMed
1986
58. Sung,C.K. and Dresden,M.H.
    Cysteinyl proteinases of Schistosoma mansoni eggs: purification and partial characterization
    J Parasitol72, 891-900. PubMed  Europe PubMed
1979
59. Asch,H.L. and Dresden,M.H.
    Acidic thiol proteinase activity of Schistosoma mansoni egg extracts
    J Parasitol65, 543-549. PubMed  Europe PubMed