$VAR1 = undef;

Summary for peptidase C01.062: cathepsin B-like peptidase (platyhelminth)

Names
MEROPS Name	cathepsin B-like peptidase (platyhelminth)
Other names	cathepsin B1 (Schistosoma mansoni), cathepsin B1 (Trichobilharzia sp.), cb1 g.p. (Schistosoma mansoni), Sj31 protein (Schistosoma japonica), Sm31 protein (Schistosoma mansoni), SmCB1 peptidase (Schistosoma mansoni)

Domain architecture

MEROPS Classification
Classification	Clan CA >> Subclan (none) >> Family C1 >> Subfamily A >> C01.062
Holotype	cathepsin B-like peptidase (platyhelminth) (Schistosoma mansoni), Uniprot accession P25792 (peptidase unit: 89-340), MERNUM MER0000691
History	Identifier created: MEROPS 3.02 (25 June 1998)

Activity
Catalytic type	Cysteine
NC-IUBMB	Not yet included in IUBMB recommendations.
Physiology	Parasite nutrition by digestion of host proteins.
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/-/--/-/-/- (based on 55 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	6	5	3	5	3	5	3	4
Pro	5	4	5	1	4	2	1	2
Ala	5	8	5	5	5	3	3	9
Val	3	6	5	1	6	6	7	4
Leu	5	5	7	6	4	6	8	3
Ile	0	0	0	0	0	1	0	0
Met	0	1	0	0	2	1	0	1
Phe	5	1	4	6	2	0	2	1
Tyr	0	0	3	1	0	0	2	0
Trp	0	0	2	1	2	1	1	0
Ser	1	1	1	4	5	2	2	5
Thr	2	3	4	3	2	5	5	2
Cys	0	2	0	1	0	0	0	1
Asn	0	2	2	4	1	0	4	2
Gln	0	0	0	1	0	0	1	2
Asp	4	4	2	1	2	2	3	2
Glu	3	2	1	0	0	3	0	1
Lys	4	2	2	4	6	5	2	3
Arg	0	0	3	9	1	0	0	1
His	2	3	6	2	0	3	1	2