Literature for peptidase C01.033: cathepsin L1 (Fasciola sp.)

(Topics flags: A Assay, S Structure, T Target, I Inhibitor, E Expression, L Localization, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Chansap,S., Cheukamud,W., Suthisintong,T., Kueakhai,P. and Changklungmoa,N.
   Development of multi-epitope Cathepsin L driven short peptide vaccine against Fasciola gigantica
   Front Vet Sci12, 1547937-1547937. PubMed  Europe PubMed DOI
2024
2. Alhassan,H.H., Ullah,M.I., Niazy,A.A., Alzarea,S.I., Alsaidan,O.A., Alzarea,A.I., Alsaidan,A.A., Alhassan,A.A., Alruwaili,M. and Alruwaili,Y.S.
   Exploring glutathione transferase and Cathepsin L-like proteinase for designing of epitopes-based vaccine against Fasciola hepatica by immunoinformatics and biophysics studies
   Front Immunol15, 1478107-1478107. PubMed  Europe PubMed DOI
2023
3. Artia,Z., Ferraro,F., Sanchez,C., Cerecetto,H., Gil,J., Pareja,L., Alonzo,M.N., Freire,T., Cabrera,M. and Corvo,I.
   In vitro and in vivo studies on a group of chalcones find promising results as potential drugs against fascioliasis
   Exp Parasitol255, 108628-108628. PubMed  Europe PubMed DOI
4. Corrales,J.L., McEvoy,A., Lalor,R., Cwiklinski,K., Doyle,S., Parkinson,M., Keane,O.M., Dalton,J.P. and Dorey,A.L.
   The use of cathepsin L1 (FhCL1) serological ELISA in sentinel screening for liver fluke on sheep farms
   Vet Parasitol Reg Stud Reports45, 100924-100924. PubMed  Europe PubMed DOI
5. Liu,S., Zhang,N., Yu,Q., Li,J., Wang,X., Li,X., Zhang,X., Cheng,S., Yue,T., Zhang,H., Gong,P. and Zhang,X.
   Immunol detection of cathepsin L from Fasciola hepatica infection in sheep by monoclonal antibody-based colloidal gold test strip assay
   Acta Biochim Biophys Sin (Shanghai)55, 1668-1671. PubMed  Europe PubMed DOI
6. Suksomboon,P., Kueakhai,P. and Changklungmoa,N.
   Fasciola gigantica Cathepsin L1H: High Sensitivity and Specificity of Immunochromatographic Strip Test for Antibody Detection
   Trop Med Infect Dis8, PubMed  Europe PubMed DOI
2022
7. Fereig,R.M., Metwally,S., El-Alfy,E.S., Abdelbaky,H.H., Shanab,O., Omar,M.A. and Alsayeqh,A.F.
   High relatedness of bioinformatic data and realistic experimental works on the potentials of Fasciola hepatica and F. gigantica cathepsin L1 as a diagnostic and vaccine antigen
   Front Public Health10, 1054502-1054502. PubMed  Europe PubMed DOI
2021
8. Cwiklinski,K., Robinson,M.W., Donnelly,S. and Dalton,J.P.
   Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver
   BMC Genomics22, 46-46. PubMed  Europe PubMed DOI
9. Sugiyama,T., Ichikawa-Seki,M., Sato,H., Kounosu,A., Tanaka,M. and Maruyama,H.
   Enzyme-linked immunosorbent assay (ELISA) using recombinant Fasciola cathepsin L1 for the diagnosis of human fasciolosis caused by Fasciola hepatica/gigantica hybrid type
   Parasitol Int82, 102311-102311. PubMed  Europe PubMed DOI
10. Villa-Mancera,A., Olivares-Perez,J., Olmedo-Juarez,A. and Reynoso-Palomar,A.
    Phage display-based vaccine with cathepsin L and excretory-secretory products mimotopes of Fasciola hepatica induces protective cellular and humoral immune responses in sheep
    Vet Parasitol289, 109340-109340. PubMed  Europe PubMed DOI
11. Villa-Mancera,A., Alcala-Canto,Y., Olivares-Perez,J., Molina-Mendoza,P., Hernandez-Guzman,K., Utrera-Quintana,F., Carreon-Luna,L., Olmedo-Juarez,A. and Reynoso-Palomar,A.
    Vaccination with cathepsin L mimotopes of Fasciola hepatica in goats reduces worm burden, morphometric measurements, and reproductive structures
    Microb Pathog155, 104859-104859. PubMed  Europe PubMed DOI
2020
12. Aftab,A., Lall,R., Bisen,S., Anandanarayanan,A., Rialch,A., Chamuah,J.K., Yadav,S., Silamparasan,M. and Raina,O.K.
    Serodiagnosis of Fasciola gigantica infection in buffaloes with native cathepsin-L proteases and recombinant cathepsin L1-D
    Acta Parasitol65, 413-421. PubMed  Europe PubMed DOI
13. Buffoni,L., Garza-Cuartero,L., Perez-Caballero,R., Zafra,R., Javier Martinez-Moreno,F., Molina-Hernandez,V., Perez,J., Martinez-Moreno,A. and Mulcahy,G.
    Identification of protective peptides of Fasciola hepatica-derived cathepsin L1 (FhCL1) in vaccinated sheep by a linear B-cell epitope mapping approach
    Parasit Vectors13, 390-390. PubMed  Europe PubMed DOI
14. Mokhtarian,K., Falak,R. and Heidari,Z.
    Evaluation of Gelatinolytic and Collagenolytic Activity of Fasciola hepatica Recombinant Cathepsin-L1
    Iran J Biotechnol18, e2357-e2357. PubMed  Europe PubMed DOI  L
15. Pritsch,I.C., Tikhonova,I.G., Jewhurst,H.L., Drysdale,O., Cwiklinski,K., Molento,M.B., Dalton,J.P. and Verissimo,C.M.
    Regulation of the Fasciola hepatica newly excysted juvenile cathepsin L3 (FhCL3) by its propeptide: a proposed 'clamp-like' mechanism of binding and inhibition
    BMC Mol Cell Biol21, 90-90. PubMed  Europe PubMed DOI
16. Sadaow,L., Yamasaki,H., Morishima,Y., Sanpool,O., Rodpai,R., Janwan,P., Boonroumkaew,P., Maleewong,W. and Intapan,P.M.
    Effectiveness of Fasciola gigantica excretory-secretory and recombinant cathepsin L antigens for rapid diagnosis of human fascioliasis using immunochromatographic devices
    Parasitol Res119, 3691-3698. PubMed  Europe PubMed DOI
17. Sato,H., Hiraya,H., Sugiyama,T., Fukumoto,S., Matsuyama,R., Yanagawa,Y., Nakao,R., Irie,T., Taira,K., Yamazaki,A., Hagiwara,K., Yoshida,A., Kamata,Y. and Ichikawa-Seki,M.
    Seroprevalence of fasciolosis in Hokkaido sika deer (Cervus nippon yesoensis) from Hokkaido Prefecture, Japan revealed by ELISA using recombinant cathepsin L1
    Parasitol Int80, 102222-102222. PubMed  Europe PubMed DOI
18. Smith,D., Cwiklinski,K., Jewhurst,H., Tikhonova,I.G. and Dalton,J.P.
    An atypical and functionally diverse family of Kunitz-type cysteine/serine proteinase inhibitors secreted by the helminth parasite Fasciola hepatica
    Sci Rep10, 20657-20657. PubMed  Europe PubMed DOI
2019
19. Cwiklinski,K., Donnelly,S., Drysdale,O., Jewhurst,H., Smith,D., De Marco Verissimo,C., Pritsch,I.C., O'Neill,S., Dalton,J.P. and Robinson,M.W.
    The cathepsin-like cysteine peptidases of trematodes of the genus Fasciola
    Adv Parasitol104, 113-164. PubMed  Europe PubMed DOI
20. Ferraro,F., Merlino,A., Gil,J., Cerecetto,H., Corvo,I. and Cabrera,M.
    Cathepsin L inhibitors with activity against the liver fluke identified from a focus library of quinoxaline 1,4-di-N-oxide derivatives
    Molecules24, PubMed  Europe PubMed DOI  I
21. Norbury,L.J., Basalaj,K., Baska,P., Kalinowska,A., Zawistowska-Deniziak,A., Yap,H.Y., Wilkowski,P., Wesolowska,A. and Wedrychowicz,H.
    Construction of a novel phage display antibody library against Fasciola hepatica, and generation of a single-chain variable fragment specific for F. hepatica cathepsin L1
    Exp Parasitol198, 87-94. PubMed  Europe PubMed DOI
2016
22. Anuracpreeda,P., Chawengkirttikul,R. and Sobhon,P.
    Immunodiagnosis of Fasciola gigantica infection using monoclonal antibody-based sandwich ELISA and immunochromatographic assay for detection of circulating cathepsin L1 protease
    PLoS ONE11, e0145650-e0145650. PubMed  Europe PubMed DOI
23. Ferraro,F., Merlino,A., dellOca,N., Gil,J., Tort,J.F., Gonzalez,M., Cerecetto,H., Cabrera,M. and Corvo,I.
    Identification of chalcones as Fasciola hepatica cathepsin L inhibitors using a comprehensive experimental and computational approach
    PLoS Negl Trop Dis10, e0004834-e0004834. PubMed  Europe PubMed DOI  I
24. Hernandez-Guzman,K., Sahagun-Ruiz,A., Vallecillo,A.J., Cruz-Mendoza,I. and Quiroz-Romero,H.
    Construction and evaluation of a chimeric protein made from Fasciola hepatica leucine aminopeptidase and cathepsin L1
    J Helminthol90, 7-13. PubMed  Europe PubMed DOI  E
25. Mokhtarian,K., Akhlaghi,L., Mohammadi,M., Meamar,A.R., Razmjou,E., Khoshmirsafa,M. and Falak,R.
    Evaluation of anti-cathepsin L1: a more reliable method for serodiagnosis of human fasciolosis
    Trans R Soc Trop Med Hyg110, 542-550. PubMed  Europe PubMed DOI
2015
26. Meemon,K. and Sobhon,P.
    Juvenile-specific cathepsin proteases in Fasciola spp.: their characteristics and vaccine efficacies
    Parasitol Res114, 2807-2813. PubMed  Europe PubMed DOI
27. Sansri,V., Meemon,K., Changklungmoa,N., Kueakhai,P., Chantree,P., Chaichanasak,P., Lorsuwannarat,N., Itagaki,T. and Sobhon,P.
    Protection against Fasciola gigantica infection in mice by vaccination with recombinant juvenile-specific cathepsin L
    Vaccine33, 1596-1601. PubMed  Europe PubMed DOI
28. Wongwairot,S., Kueakhai,P., Changklungmoa,N., Jaikua,W., Sansri,V., Meemon,K., Songkoomkrong,S., Riengrojpitak,S. and Sobhon,P.
    Monoclonal antibody against recombinant Fasciola gigantica cathepsin L1H could detect juvenile and adult cathepsin Ls of Fasciola gigantica
    Parasitol Res114, 133-140. PubMed  Europe PubMed DOI
2014
29. Lustigman,S., Melnikow,E., Anand,S.B., Contreras,A., Nandi,V., Liu,J., Bell,A., Unnasch,T.R., Rogers,M.B. and Ghedin,E.
    Potential involvement of Brugia malayi cysteine proteases in the maintenance of the endosymbiotic relationship with Wolbachia
    Int J Parasitol Drugs Drug Resist4, 267-277. PubMed  Europe PubMed DOI
2013
30. Gonzales Santana,B., Dalton,J.P., Vasquez Camargo,F., Parkinson,M. and Ndao,M.
    The diagnosis of human fascioliasis by enzyme-linked immunosorbent assay (ELISA) using recombinant cathepsin L protease
    PLoS Negl Trop Dis7, e2414-e2414. PubMed  Europe PubMed DOI
31. Sansri,V., Changklungmoa,N., Chaichanasak,P., Sobhon,P. and Meemon,K.
    Molecular cloning, characterization and functional analysis of a novel juvenile-specific cathepsin L of Fasciola gigantica
    Acta Trop128, 76-84. PubMed  Europe PubMed DOI
32. Wesolowska,A., Norbury,L.J., Januszkiewicz,K., Jedlina,L., Jaros,S., Zawistowska-Deniziak,A., Zygner,W. and Wedrychowicz,H.
    Evaluation of the immune response of male and female rats vaccinated with cDNA encoding a cysteine proteinase of Fasciola hepatica (FhPcW1)
    Acta Parasitol58, 198-206. PubMed  Europe PubMed DOI
2012
33. McVeigh,P., Maule,A.G., Dalton,J.P. and Robinson,M.W.
    Fasciola hepatica virulence-associated cysteine peptidases: a systems biology perspective
    Microbes Infect14, 301-310. PubMed  Europe PubMed DOI
34. Robinson,M.W., Brindley,P.J., McKerrow,J.H. and Dalton,J.P.
    Trematode cysteine endopeptidases
    [ISSN:978-0-12-407743-0]3, 1941-1949. DOI
2011
35. Morphew,R.M., Wright,H.A., Lacourse,E.J., Porter,J., Barrett,J., Woods,D.J. and Brophy,P.M.
    Towards delineating functions within the Fasciola secreted cathepsin L protease family by integrating in vivo based sub-proteomics and phylogenetics
    PLoS Negl Trop Dis5, e937-e937. PubMed  Europe PubMed DOI
36. Robinson,M.W., Corvo,I., Jones,P.M., George,A.M., Padula,M.P., To,J., Cancela,M., Rinaldi,G., Tort,J.F., Roche,L. and Dalton,J.P.
    Collagenolytic activities of the major secreted cathepsin L peptidases involved in the virulence of the helminth pathogen, Fasciola hepatica
    PLoS Negl Trop Dis5, e1012-e1012. PubMed  Europe PubMed DOI
37. Stack,C., Dalton,J.P. and Robinson,M.W.
    The phylogeny, structure and function of trematode cysteine proteases, with particular emphasis on the Fasciola hepatica cathepsin L family
    Adv Exp Med Biol712, 116-135. PubMed  Europe PubMed DOI  V
2010
38. Donnelly,S., O'Neill,S.M., Stack,C.M., Robinson,M.W., Turnbull,L., Whitchurch,C. and Dalton,J.P.
    Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3
    J Biol Chem285, 3383-3392. PubMed  Europe PubMed DOI
39. Golden,O., Flynn,R.J., Read,C., Sekiya,M., Donnelly,S.M., Stack,C., Dalton,J.P. and Mulcahy,G.
    Protection of cattle against a natural infection of Fasciola hepatica by vaccination with recombinant cathepsin L1 (rFhCL1)
    Vaccine28, 5551-5557. PubMed  Europe PubMed DOI
40. Jaros,S., Zygner,W., Januszkiewicz,K., Jaros,D. and Wedrychowicz,H.
    Molecular cloning and bioinformatic characterisation of FhPcW1, a new isoform of cathepsin L from adult Fasciola hepatica
    Bull Vet Inst Pulawy54, 585-590.
41. Moran,B.W., Anderson,F.P., Ruth,D.M., Fagain,C.O., Dalton,J.P. and Kenny,P.T.
    Fluorobenzoyl dipeptidyl derivatives as inhibitors of the Fasciola hepatica cysteine protease cathepsin L1
    J Enzyme Inhib Med Chem25, 1-12. PubMed  Europe PubMed DOI  I
42. Perez-Ecija,R.A., Mendes,R.E., Zafra,R., Buffonni,L., Martinez-Moreno,A. and Perez,J.
    Pathological and parasitological protection in goats immunised with recombinant cathepsin L1 and challenged with Fasciola hepatica
    Vet J185, 351-353. PubMed  Europe PubMed DOI
2009
43. Kasny,M., Mikes,L., Hampl,V., Dvorak,J., Caffrey,C.R., Dalton,J.P. and Horak,P.
    Chapter 4. Peptidases of trematodes
    Adv Parasitol69, 205-297. PubMed  Europe PubMed DOI  V
44. Lowther,J., Robinson,M.W., Donnelly,S.M., Xu,W., Stack,C.M., Matthews,J.M. and Dalton,J.P.
    The importance of pH in regulating the function of the Fasciola hepatica cathepsin L1 cysteine protease
    PLoS Negl Trop Dis3, e369-e369. PubMed  Europe PubMed DOI
2008
45. Dixit,A.K., Dixit,P. and Sharma,R.L.
    Immunodiagnostic/protective role of cathepsin L cysteine proteinases secreted by Fasciola species
    Vet Parasitol154, 177-184. PubMed  Europe PubMed DOI  T
46. Jezek,J., El Ridi,R., Salah,M., Wagih,A., Aziz,H.W., Tallima,H., El Shafie,M.H., Khalek,T.A., Ammou,F.F., Strongylis,C., Moussis,V. and Tsikaris,V.
    Fasciola gigantica cathepsin L proteinase-based synthetic peptide for immunodiagnosis and prevention of sheep fasciolosis
    Biopolymers90, 349-357. PubMed  Europe PubMed DOI
47. Kuk,S. and Erensoy,A.
    [Gene cloning, selection of plasmids and application of Fasciola hepatica cathepsin L1 gene]
    Turkiye Parazitol Derg32, 16-22. PubMed  Europe PubMed
48. McGonigle,L., Mousley,A., Marks,N.J., Brennan,G.P., Dalton,J.P., Spithill,T.W., Day,T.A. and Maule,A.G.
    The silencing of cysteine proteases in Fasciola hepatica newly excysted juveniles using RNA interference reduces gut penetration
    Int J Parasitol38, 149-155. PubMed  Europe PubMed DOI
49. Robinson,M.W., Dalton,J.P. and Donnelly,S.
    Helminth pathogen cathepsin proteases: it's a family affair
    Trends Biochem Sci33, 601-608. PubMed  Europe PubMed DOI  V
50. Robinson,M.W., Tort,J.F., Lowther,J., Donnelly,S.M., Wong,E., Xu,W., Stack,C.M., Padula,M., Herbert,B. and Dalton,J.P.
    Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors
    Mol Cell Proteomics7, 1111-1123. PubMed  Europe PubMed DOI
51. Stack,C.M., Caffrey,C.R., Donnelly,S.M., Seshaadri,A., Lowther,J., Tort,J.F., Collins,P.R., Robinson,M.W., Xu,W., McKerrow,J.H., Craik,C.S., Geiger,S.R., Marion,R., Brinen,L.S. and Dalton,J.P.
    Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica
    J Biol Chem283, 9896-9908. PubMed  Europe PubMed DOI  S
2007
52. Kesik,M., Jedlina-Panasiuk,L., Kozak-Cieszczyk,M., Plucienniczak,A. and Wedrychowicz,H.
    Enteral vaccination of rats against Fasciola hepatica using recombinant cysteine proteinase (cathepsin L1)
    Vaccine25, 3619-3628. PubMed  Europe PubMed DOI
53. Stack,C.M., Donnelly,S., Lowther,J., Xu,W., Collins,P.R., Brinen,L.S. and Dalton,J.P.
    The major secreted cathepsin L1 protease of the liver fluke, Fasciola hepatica: A leu-12 to pro-12 replacement in the nonconserved C-terminal region of the prosegment prevents complete enzyme autoactivation and allows definition of the molecular events in prosegment removal
    J Biol Chem282, 16532-16543. PubMed  Europe PubMed DOI
54. Wedrychowicz,H., Kesik,M., Kaliniak,M., Kozak-Cieszczyk,M., Jedlina-Panasiuk,L., Jaros,S. and Plucienniczak,A.
    Vaccine potential of inclusion bodies containing cysteine proteinase of Fasciola hepatica in calves and lambs experimentally challenged with metacercariae of the fluke
    Vet Parasitol147, 77-88. PubMed  Europe PubMed DOI
2006
55. [YEAR:27-4-2006]Raina,O.K., Yadav,S.C., Sriveny,D. and Gupta,S.C.
    Immuno-diagnosis of bubaline fasciolosis with Fasciola gigantica cathepsin-L and recombinant cathepsin L 1-D proteases
    Acta Trop98, 145-151. PubMed  Europe PubMed DOI
56. [YEAR:6-7-2006]Ruth,D.M., McMahon,G. and O'Fagain,C.
    Peptide synthesis by recombinant Fasciola hepatica cathepsin L1
    Biochimie88, 117-120. PubMed  Europe PubMed DOI
57. [YEAR:17-11-2006]Sriveny,D., Raina,O.K., Yadav,S.C., Chandra,D., Jayraw,A.K., Singh,M., Velusamy,R. and Singh,B.P.
    Cathepsin L cysteine proteinase in the diagnosis of bovine Fasciola gigantica infection
    Vet Parasitol135, 25-31. PubMed  Europe PubMed DOI
2005
58. [YEAR:14-9-2005]Intapan,P.M., Tantrawatpan,C., Maleewong,W., Wongkham,S., Wongkham,C. and Nakashima,K.
    Potent epitopes derived from Fasciola gigantica cathepsin L1 in peptide-based immunoassay for the serodiagnosis of human fascioliasis
    Diagn Microbiol Infect Dis53, 125-129. PubMed  Europe PubMed DOI  A
59. [YEAR:13-10-2005]Yadav,S.C., Saini,M., Raina,O.K., Nambi,P.A., Jadav,K. and Sriveny,D.
    Fasciola gigantica cathepsin-L cysteine proteinase in the detection of early experimental fasciolosis in ruminants
    Parasitol Res97, 527-534. PubMed  Europe PubMed DOI
2004
60. [YEAR:30-1-2004]Collins,P.R., Stack,C.M., O'Neill,S.M., Doyle,S., Ryan,T., Brennan,G.P., Mousley,A., Stewart,M., Maule,A.G., Dalton,J.P. and Donnelly,S.
    Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propeptide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells
    J Biol Chem279, 17038-17046. PubMed  Europe PubMed DOI
61. Dalton,J.P., McKerrow,J.H. and Brindley,P.J.
    Trematode cysteine endopeptidases
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2003
62. [YEAR:30-9-2003]Dalton,J.P., Neill,S.O., Stack,C., Collins,P., Walshe,A., Sekiya,M., Doyle,S., Mulcahy,G., Hoyle,D., Khaznadji,E., Moire,N., Brennan,G., Mousley,A., Kreshchenko,N., Maule,A.G. and Donnelly,S.M.
    Fasciola hepatica cathepsin L-like proteases: biology, function, and potential in the development of first generation liver fluke vaccines
    Int J Parasitol33, 1173-1181. PubMed  Europe PubMed DOI
63. Irving,J.A., Spithill,T.W., Pike,R.N., Whisstock,J.C. and Smooker,P.M.
    The evolution of enzyme specificity in Fasciola spp
    J Mol Evol57, 1-15. PubMed  Europe PubMed DOI
2002
64. Cappetta,M., Roth,I., Diaz,A., Tort,J. and Roche,L.
    Role of the prosegment of Fasciola hepatica cathepsin L1 in folding of the catalytic domain
    Biol Chem383, 1215-1221. PubMed  Europe PubMed DOI
65. Sajid,M. and McKerrow,J.H.
    Cysteine proteases of parasitic organisms
    Mol Biochem Parasitol120, 1-21. PubMed  Europe PubMed
2001
66. Carnevale,S., Rodriguez,M.I., Guarnera,E.A., Carmona,C., Tanos,T. and Angel,S.O.
    Immunodiagnosis of fasciolosis using recombinant procathepsin L cystein proteinase
    Diagn Microbiol Infect Dis41, 43-49. PubMed  Europe PubMed DOI
67. [YEAR:3-9-2001]Cordova,M., Jara,J., Del Nery,E., Hirata,I.Y., Araujo,M.S., Carmona,A.K., Juliano,M.A. and Juliano,L.
    Characterization of two cysteine proteinases secreted by Fasciola hepatica and demonstration of their kininogenase activity
    Mol Biochem Parasitol116, 109-115. PubMed  Europe PubMed DOI
68. Grams,R., Vichasri-Grams,S., Sobhon,P., Upatham,E.S. and Viyanant,V.
    Molecular cloning and characterization of cathepsin L encoding genes from Fasciola gigantica
    Parasitol Int50, 105-114. PubMed  Europe PubMed DOI
69. Mulcahy,G. and Dalton,J.P.
    Cathepsin L proteinases as vaccines against infection with Fasciola hepatica (liver fluke) in ruminants
    Res Vet Sci70, 83-86. PubMed  Europe PubMed DOI
70. O'Neill,S.M., Mills,K.H. and Dalton,J.P.
    Fasciola hepatica cathepsin L cysteine proteinase suppresses Bordetella pertussis-specific interferon-gamma production in vivo
    Parasite Immunol23, 541-547. PubMed  Europe PubMed DOI
2000
71. Berasain,P., Carmona,C., Frangione,B., Dalton,J.P. and Goni,F.
    Fasciola hepatica: parasite-secreted proteinases degrade all human IgG subclasses: determination of the specific cleavage sites and identification of the immunoglobulin fragments produced
    Exp Parasitol94, 99-110. PubMed  Europe PubMed DOI
72. Dowd,A.J., Dooley,M., Fagain,C. and Dalton,J.P.
    Stability studies on the cathepsin L proteinase of the helminth parasite, Fasciola hepatica
    Enzyme Microb Technol27, 599-604. PubMed  Europe PubMed
73. [YEAR:14-10-2000]Hawthorne,S.J., Pagano,M., Halton,D.W. and Walker,B.
    Partial characterization of a novel cathepsin L-like protease from Fasciola hepatica
    Biochem Biophys Res Commun277, 79-82. PubMed  Europe PubMed DOI
74. [YEAR:1-7-2000]Kofta,W., Mieszczanek,J., Plucienniczak,G. and Wedrychowicz,H.
    Successful DNA immunisation of rats against fasciolosis
    Vaccine18, 2985-2990. PubMed  Europe PubMed
75. Smooker,P.M., Whisstock,J.C., Irving,J.A., Siyaguna,S., Spithill,T.W. and Pike,R.N.
    A single amino acid substitution affects substrate specificity in cysteine proteinases from Fasciola hepatica
    Protein Sci9, 2567-2572. PubMed  Europe PubMed DOI
1999
76. O'Neill,S.M., Parkinson,M., Dowd,A.J., Strauss,W., Angles,R. and Dalton,J.P.
    Immunodiagnosis of human fascioliasis using recombinant Fasciola hepatica cathepsin L1 cysteine proteinase
    Am J Trop Med Hyg60, 749-751. PubMed  Europe PubMed
77. Piacenza,L., Acosta,D., Basmadjian,I., Dalton,J.P. and Carmona,C.
    Vaccination with cathepsin L proteinases and with leucine aminopeptidase induces high levels of protection against fascioliasis in sheep
    Infect Immun67, 1954-1961. PubMed  Europe PubMed
78. [YEAR:25-1-1999]Roche,L., Tort,J. and Dalton,J.P.
    The propeptide of Fasciola hepatica cathepsin L is a potent and selective inhibitor of the mature enzyme
    Mol Biochem Parasitol98, 271-277. PubMed  Europe PubMed DOI
79. Strauss,W., O'Neill,S.M., Parkinson,M., Angles,R. and Dalton,J.P.
    Diagnosis of human fascioliasis: detection of anti-cathepsin L antibodies in blood samples collected on filter paper
    Am J Trop Med Hyg60, 746-748. PubMed  Europe PubMed
80. Tort,J., Brindley,P.J., Knox,D., Wolfe,K.H. and Dalton,J.P.
    Proteinases and associated genes of parasitic helminths
    Adv Parasitol43, 161-266. PubMed  Europe PubMed  V
1998
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