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Literature for peptidase A01.011: penicillopepsin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, P Specificity, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. Guo,Y., Li,X., Jia,W., Huang,F., Liu,Y. and Zhang,C.
    Characterization of an intracellular aspartic protease (PsAPA) from Penicillium sp. XT7 and its application in collagen extraction
    Food Chem345, 128834-128834. PubMed  Europe PubMed DOI
    2. 2012
  2. Hofmann,T.
    Penicillopepsin
    [ISSN:978-0-12-407744-7]3, 141-146. DOI
    3. 2000
  3. Cao,Q.N., Stubbs,M., Ngo,K.Q., Ward,M., Cunningham,A., Pai,E.F., Tu,G.C. and Hofmann,T.
    Penicillopepsin-JT2, a recombinant enzyme from Penicillium janthinellum and the contribution of a hydrogen bond in subsite S3 to k(cat)
    Protein Sci9, 991-1001. PubMed  Europe PubMed DOI
    4. 1998
  4. [YEAR:20-5-1998]Ding,J.H., Fraser,M.E., Meyer,J.H., Bartlett,P.A. and James,M.N.G.
    Macrocyclic inhibitors of penicillopepsin. 2. X-ray crystallographic analyses of penicillopepsin complexed with a P3-P1 macrocyclic peptidyl inhibitor and with its two acyclic analogues
    J Am Chem Soc120, 4610-4621. DOI  S  I
  5. [YEAR:1-12-1998]Khan,A.R., Parrish,J.C., Fraser,M.E., Smith,W.W., Bartlett,P.A. and James,M.N.
    Lowering the entropic barrier for binding conformationally flexible inhibitors to enzymes
    Biochemistry37, 16839-16845. PubMed  Europe PubMed DOI  I
  6. [YEAR:20-5-1998]Meyer,J.H. and Bartlett,P.A.
    Macrocyclic inhibitors of penicillopepsin. I. Design, synthesis, and evaluation of an inhibitor bridged between P1 and P3
    J Am Chem Soc120, 4600-4609. DOI  I
  7. [YEAR:20-5-1998]Smith,W.W. and Bartlett,P.A.
    Macrocyclic inhibitors of penicillopepsin. 3. Design, synthesis, and evaluation of an inhibitor bridged between P2 and P1'
    J Am Chem Soc120, 4622-4628.  I
    8. 1997
  8. Bracq,E., Levieux,A. and Levieux,D.
    Purification and immunochemical quantitation of Penicillium roqueforti acid aspartyl proteinase
    J Dairy Res64, 105-113.
  9. Gente,S., Durand-Poussereau,N. and Fevre,M.
    Controls of the expression of aspA, the aspartyl protease gene from Penicillium roqueforti
    Mol Gen Genet256, 557-565. PubMed  Europe PubMed DOI
  10. Shintani,T., Nomura,K. and Ichishima,E.
    Engineering of porcine pepsin. Alteration of S1 substrate specificity of pepsin to those of fungal aspartic proteinases by site-directed mutagenesis
    J Biol Chem272, 18855-18861. PubMed  Europe PubMed DOI
    11. 1995
  11. Chrzanowska,J., Kolaczkowska,M., Dryjanski,M., Stachowiak,D. and Polanowski,A.
    Aspartic proteinase from Penicillium camemberti: purification, properties, and substrate specificity
    Enzyme Microb Technol17, 719-724. PubMed  Europe PubMed DOI  I
    12. 1992
  12. Fraser,M.E., Strynadka,N.C., Bartlett,P.A., Hanson,J.E. and James,M.N.
    Crystallographic analysis of transition-state mimics bound to penicillopepsin: phosphorus-containing peptide analogues
    Biochemistry31, 5201-5214. PubMed  Europe PubMed  I
  13. James,M.N., Sielecki,A.R., Hayakawa,K. and Gelb,M.H.
    Crystallographic analysis of transition state mimics bound to penicillopepsin: difluorostatine- and difluorostatone-containing peptides
    Biochemistry31, 3872-3886. PubMed  Europe PubMed DOI  S  I
    14. 1991
  14. [YEAR:25-5-1991]Blum,M., Cunningham,A., Pang,H. and Hofmann,T.
    Mechanism and pathway of penicillopepsin-catalyzed transpeptidation and evidence for noncovalent trapping of amino acid and peptide intermediates
    J Biol Chem266, 9501-9507. PubMed  Europe PubMed
    15. 1990
  15. [YEAR:25-3-1990]Allen,B., Blum,M., Cunningham,A., Tu,G.C. and Hofmann,T.
    A ligand-induced, temperature-dependent conformational change in penicillopepsin. Evidence from nonlinear Arrhenius plots and from circular dichroism studies
    J Biol Chem265, 5060-5065. PubMed  Europe PubMed
  16. [YEAR:10-12-1990]Cunningham,A., Hofmann,M.I. and Hofmann,T.
    Rate-determining steps in penicillopepsin-catalysed reactions
    FEBS Lett276, 119-122. PubMed  Europe PubMed DOI
    17. 1988
  17. [YEAR:23-2-1988]Hofmann,T., Allen,B., Bendiner,M., Blum,M. and Cunningham,A.
    Effect of secondary substrate binding in penicillopepsin: contributions of subsites S3 and S2' to kcat
    Biochemistry27, 1140-1146. PubMed  Europe PubMed
    18. 1985
  18. [YEAR:2-7-1985]James,M.N. and Sielecki,A.R.
    Stereochemical analysis of peptide bond hydrolysis catalyzed by the aspartic proteinase penicillopepsin
    Biochemistry24, 3701-3713. PubMed  Europe PubMed  S
  19. James,M.N.G., Sielecki,A.R. and Hofmann,T.
    X-ray diffraction studies on penicillopepsin and its complexes: the hydrolytic mechanism
    165-177.  S
    20. 1984
  20. [YEAR:14-2-1984]Hofmann,T., Hodges,R.S. and James,M.N.
    Effect of pH on the activities of penicillopepsin and Rhizopus pepsin and a proposal for the productive substrate binding mode in penicillopepsin
    Biochemistry23, 635-643. PubMed  Europe PubMed
  21. [YEAR:23-10-1984]Hofmann,T., Fink,A.L. and Dunn,B.M.
    Cryoenzymology of penicillopepsin; with an appendix: mechanism of action of aspartyl proteinases
    Biochemistry23, 5247-5256. PubMed  Europe PubMed
    22. 1983
  22. James,M.N. and Sielecki,A.R.
    Structure and refinement of penicillopepsin at 1.8 A resolution
    J Mol Biol163, 299-361. PubMed  Europe PubMed  S
    23. 1982
  23. [YEAR:1-6-1982]Hofmann,T. and Hodges,R.S.
    A new chromophoric substrate for penicillopepsin and other fungal aspartic proteinases
    Biochem J203, 603-610. PubMed  Europe PubMed
  24. James,M.N., Sielecki,A., Salituro,F., Rich,D.H. and Hofmann,T.
    Conformational flexibility in the active sites of aspartyl proteinases revealed by a pepstatin fragment binding to penicillopepsin
    Proc Natl Acad Sci U S A79, 6137-6141. PubMed  Europe PubMed  S  I
  25. Trieu-Cuot,P., Archieri-Haze,M.-J. and Gripon,J.-C.
    Effect of aspartyl proteinases of Penicillium caseicolum and Penicillium roqueforti on caseins
    J Dairy Res49, 487-500. DOI  P
    26. 1977
  26. [YEAR:30-6-1977]James,M.N., Hsu,I.N. and Delbaere,L.T.
    Mechanism of acid protease catalysis based on the crystal structure of penicillopepsin
    Nature267, 808-813. PubMed  Europe PubMed
    27. 1976
  27. Emi,S., Myers,D.V. and Iacobucci,G.A.
    Purification and properties of the thermostable acid protease of Penicillium duponti
    Biochemistry15, 842-848. PubMed  Europe PubMed  I
  28. Hofmann,T.
    Penicillopepsin
    Methods Enzymol45, 434-452. PubMed  Europe PubMed DOI  V
    29. 1974
  29. [YEAR:15-3-1974]Takahashi,M., Wang,T.T. and Hofmann,T.
    Acyl intermediates in pepsin and penicillopepsin catalyzed reactions
    Biochem Biophys Res Commun57, 39-46. PubMed  Europe PubMed
    30. 1972
  30. Abdel-Fattah,A.F. and Abdel-Fattah-El-Hawwary,N.M.
    Purification and proteolytic action of milk-clotting enzyme produced by Penicillium citrinum
    J Gen Appl Microbiol18, 341-348. DOI
    31. 1971
  31. Mains,G., Takahashi,M., Sodek,J. and Hofmann,T.
    The specificity of penicillopepsin
    Can J Biochem49, 1134-1149. PubMed  Europe PubMed  P
    32. 1970
  32. Sodek,J. and Hofmann,T.
    Amino acid sequence around the active site aspartic acid in penicillopepsin
    Can J Biochem48, 1014-1016. PubMed  Europe PubMed
    33. 1938
  33. [YEAR:20-5-1938]Kunitz,M.
    Formation of trypsin from trypsinogen by an enzyme produced by a mold of the genus Penicillium
    J Gen Physiol21, 601-620. PubMed  Europe PubMed DOI

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