Literature for peptidase M27.002: bontoxilysin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(References are filtered for relevance to Therapeutic. To remove the filter click here. See explanation.)

    2019
  1. Elliott,M., Favre-Guilmard,C., Liu,S.M., Maignel,J., Masuyer,G., Beard,M., Boone,C., Carre,D., Kalinichev,M., Lezmi,S., Mir,I., Nicoleau,C., Palan,S., Perier,C., Raban,E., Zhang,S., Dong,M., Stenmark,P. and Krupp,J.
    Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models
    Sci Adv5, eaau7196-eaau7196. PubMed  Europe PubMed DOI  U
  2. Kerscher,M., Wanitphakdeedecha,R., Trindade de Almeida,A., Maas,C. and Frevert,J.
    IncobotulinumtoxinA: a highly purified and precisely manufactured Botulinum neurotoxin type A
    J Drugs Dermatol18, 52-57. PubMed  Europe PubMed  U
  3. 2017
  4. Awan,K.H.
    The therapeutic usage of botulinum toxin (Botox) in non-cosmetic head and neck conditions - An evidence based review
    Saudi Pharm J25, 18-24. PubMed  Europe PubMed DOI  U
  5. Olbrich,K., Costard,L., Moser,C.V., Syhr,K.M., King-Himmelreich,T.S., Wolters,M.C., Schmidtko,A., Geisslinger,G. and Niederberger,E.
    Cleavage of SNAP-25 ameliorates cancer pain in a mouse model of melanoma
    Eur J Pain21, 101-111. PubMed  Europe PubMed DOI  U
  6. Wang,J., Casals-Diaz,L., Zurawski,T., Meng,J., Moriarty,O., Nealon,J., Edupuganti,O.P. and Dolly,O.
    A novel therapeutic with two SNAP-25 inactivating proteases shows long-lasting anti-hyperalgesic activity in a rat model of neuropathic pain
    Neuropharmacology118, 223-232. PubMed  Europe PubMed DOI  U
  7. 2016
  8. Vazquez-Cintron,E., Tenezaca,L., Angeles,C., Syngkon,A., Liublinska,V., Ichtchenko,K. and Band,P.
    Pre-clinical study of a novel recombinant Botulinum neurotoxin derivative engineered for improved safety
    Sci Rep6, 30429-30429. PubMed  Europe PubMed DOI  U
  9. 2013
  10. Bigalke,H.
    Botulinum toxin: application, safety, and limitations
    Curr Top Microbiol Immunol364, 307-317. PubMed  Europe PubMed DOI  U
  11. Hawlitschka,A., Antipova,V., Schmitt,O., Witt,M., Benecke,R., Mix,E. and Wree,A.
    Intracerebrally applied Botulinum neurotoxin in experimental neuroscience
    Curr Pharm Biotechnol14, 124-130. PubMed  Europe PubMed  U
  12. 2012
  13. Dolly,J.O. and O'Connell,M.A.
    Neurotherapeutics to inhibit exocytosis from sensory neurons for the control of chronic pain
    Curr Opin Pharmacol12, 100-108. PubMed  Europe PubMed DOI  U
  14. Peng Chen,Z., Morris,J.G., Rodriguez,R.L., Shukla,A.W., Tapia-Nunez,J. and Okun,M.S.
    Emerging opportunities for serotypes of botulinum neurotoxins
    Toxins (Basel)4, 1196-1222. PubMed  Europe PubMed DOI  U
  15. Somm,E., Bonnet,N., Martinez,A., Marks,P.M., Cadd,V.A., Elliott,M., Toulotte,A., Ferrari,S.L., Rizzoli,R., Huppi,P.S., Harper,E., Melmed,S., Jones,R. and Aubert,M.L.
    A botulinum toxin-derived targeted secretion inhibitor downregulates the GH/IGF1 axis
    J Clin Invest122, 3295-3306. PubMed  Europe PubMed DOI  U
  16. Tajti,J., Szok,D., Tuka,B., Csati,A., Kuris,A., Majlath,Z., Lukacs,M. and Vecsei,L.
    [Botulinum neurotoxin - a therapy in migraine]
    Ideggyogy Sz65, 77-82. PubMed  Europe PubMed  U
  17. 2011
  18. Capek,P., Zhang,Y., Barlow,D.J., Houseknecht,K.L., Smith,G.R. and Dickerson,T.J.
    Enhancing the pharmacokinetic properties of botulinum neurotoxin serotype A protease inhibitors through rational design
    ACS Chem Neurosci2, 288-293. PubMed  Europe PubMed DOI  U
  19. Yu,H.M., Li,Q., Zhou,X.D., Perelman,J.M. and Kolosov,V.P.
    Expression of recombinant fusion protein BoNT-LH (N)-elafin in Pichia pastoris and activity of expressed product
    Chin J Biol24, 389-393.  U
  20. 2010
  21. Carmichael,N.M., Dostrovsky,J.O. and Charlton,M.P.
    Peptide-mediated transdermal delivery of botulinum neurotoxin type A reduces neurogenic inflammation in the skin
    Pain149, 316-324. PubMed  Europe PubMed DOI  U
  22. Hexsel,D., Spencer,J.M., Woolery-Lloyd,H. and Gilbert,E.
    Practical applications of a new botulinum toxin
    J Drugs Dermatol9, s31-s37. PubMed  Europe PubMed  U
  23. 2009
  24. Chen,S. and Barbieri,J.T.
    Engineering botulinum neurotoxin to extend therapeutic intervention
    Proc Natl Acad Sci U S A106, 9180-9184. PubMed  Europe PubMed DOI  U
  25. 2008
  26. Wohlfarth,K., Schwandt,I., Wegner,F., Jurgens,T., Gelbrich,G., Wagner,A., Bogdahn,U. and Schulte-Mattler,W.
    Biological activity of two botulinum toxin type A complexes (Dysport and Botox) in volunteers: a double-blind, randomized, dose-ranging study
    J Neurol255, 1932-1939. PubMed  Europe PubMed DOI  U
  27. 1989
  28. Scott,A.B.
    Clostridial toxin as therapeutic agents
    399-412.  U