Literature for peptidase M01.024: ERAP2 aminopeptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

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    2025
  1. Su,S.H., Cai,X.Q., Li,Y.H., Xu,A.H., Huang,Q., Niu,H., You,Q.H. and Sun,G.Y.
    The important roles of ERAP1, ERAP2 genes polymorphisms and their DNA methylation levels in pulmonary tuberculosis
    BMC Infect Dis (2025) 25, 178-178. PubMed  Europe PubMed DOI  PMC  EPMC  M
  2. 2023
  3. Hamilton,F., Mentzer,A.J., Parks,T., Baillie,J.K., Smith,G.D., Ghazal,P. and Timpson,N.J.
    Variation in ERAP2 has opposing effects on severe respiratory infection and autoimmune disease
    Am J Hum Genet (2023) 110, 691-702. PubMed  Europe PubMed DOI  PMC  EPMC  M
  4. Tedeschi,V., Paldino,G., Alba,J., Molteni,E., Paladini,F., Scrivo,R., Congia,M., Cauli,A., Caccavale,R., Paroli,M., Di Franco,M., Tuosto,L., Sorrentino,R., D'Abramo,M. and Fiorillo,M.T.
    ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-Epitopes
    Int J Mol Sci (2023) 24 PubMed  Europe PubMed DOI  PMC  EPMC  M
  5. 2022
  6. Mattorre,B., Tedeschi,V., Paldino,G., Fiorillo,M.T., Paladini,F. and Sorrentino,R.
    The emerging multifunctional roles of ERAP1, ERAP2 and IRAP between antigen processing and renin-angiotensin system modulation
    Front Immunol (2022) 13, 1002375-1002375. PubMed  Europe PubMed DOI  PMC  EPMC  M
  7. Mattorre,B., Caristi,S., Donato,S., Volpe,E., Faiella,M., Paiardini,A., Sorrentino,R. and Paladini,F.
    A Short ERAP2 That Binds IRAP Is Expressed in Macrophages Independently of Gene Variation
    Int J Mol Sci (2022) 23 PubMed  Europe PubMed DOI  PMC  EPMC  M
  8. 2020
  9. Li,C., Li,Y., Yan,Z., Dai,S., Liu,S., Wang,X., Wang,J., Zhang,X., Shi,L. and Yao,Y.
    Polymorphisms in endoplasmic reticulum aminopeptidase genes are associated with cervical cancer risk in a Chinese Han population
    BMC Cancer (2020) 20, 341-341. PubMed  Europe PubMed DOI  PMC  EPMC  M
  10. 2018
  11. Warthan,M.D., Washington,S.L., Franzese,S.E., Ramus,R.M., Kim,K.R., York,T.P., Stratikos,E., Strauss JF 3rd and Lee,E.D.
    The role of endoplasmic reticulum aminopeptidase 2 in modulating immune detection of choriocarcinoma
    Biol Reprod (2018) 98, 309-322. PubMed  Europe PubMed DOI  M
  12. 2017
  13. Lee,E.D.
    Endoplasmic reticulum aminopeptidase 2, a common immunological link to adverse pregnancy outcomes and cancer clearance?
    Placenta (2017) 56, 40-43. PubMed  Europe PubMed DOI  M
  14. 2016
  15. Pedersen,N.C., Dhanota,J.K. and Liu,H.
    Polymorphisms in ERAP1 and ERAP2 are shared by Caninae and segregate within and between random- and pure-breeds of dogs
    Vet Immunol Immunopathol (2016) 179, 46-57. PubMed  Europe PubMed DOI  M
  16. 2013
  17. Biasin,M., Sironi,M., Saulle,I., De Luca,M., la Rosa,F., Cagliani,R., Forni,D., Agliardi,C., Caputo,S.L., Mazzotta,F., Trabattoni,D., Macias,J., Pineda,J.A., Caruz,A. and Clerici,M.
    Endoplasmic reticulum aminopeptidase 2 haplotypes play a role in modulating susceptibility to HIV infection
    AIDS (2013) 27, 1697-1706. PubMed  Europe PubMed DOI  M
  18. 2012
  19. Evnouchidou,I., Birtley,J., Seregin,S., Papakyriakou,A., Zervoudi,E., Samiotaki,M., Panayotou,G., Giastas,P., Petrakis,O., Georgiadis,D., Amalfitano,A., Saridakis,E., Mavridis,I.M. and Stratikos,E.
    A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing
    J Immunol (2012) 189, 2383-2392. PubMed  Europe PubMed DOI  M  P
  20. 2011
  21. Harvey,D., Pointon,J.J., Karaderi,T., Appleton,L.H., Farrar,C. and Wordsworth,B.P.
    A common functional variant of endoplasmic reticulum aminopeptidase 2 (ERAP2) that reduces major histocompatibility complex class I expression is not associated with ankylosing spondylitis
    Rheumatology (Oxford) (2011) 50, 1720-1721. PubMed  Europe PubMed DOI  M
  22. 2010
  23. Andres,A.M., Dennis,M.Y., Kretzschmar,W.W., Cannons,J.L., Lee-Lin,S.Q., Hurle,B., Schwartzberg,P.L., Williamson,S.H., Bustamante,C.D., Nielsen,R., Clark,A.G. and Green,E.D.
    Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation
    PLoS Genet (2010) 6, e1001157-e1001157. PubMed  Europe PubMed DOI  PMC  EPMC  M
  24. Cagliani,R., Riva,S., Biasin,M., Fumagalli,M., Pozzoli,U., Lo Caputo,S., Mazzotta,F., Piacentini,L., Bresolin,N., Clerici,M. and Sironi,M.
    Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection
    Hum Mol Genet (2010) 19, 4705-4714. PubMed  Europe PubMed DOI  M
  25. Tsui,F.W., Haroon,N., Reveille,J.D., Rahman,P., Chiu,B., Tsui,H.W. and Inman,R.D.
    Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis
    Ann Rheum Dis (2010) 69, 733-736. PubMed  Europe PubMed DOI  M
  26. 2009
  27. Johnson,M.P., Roten,L.T., Dyer,T.D., East,C.E., Forsmo,S., Blangero,J., Brennecke,S.P., Austgulen,R. and Moses,E.K.
    The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations
    Hum Genet (2009) 126, 655-666. PubMed  Europe PubMed DOI  PMC  EPMC  M