Literature for peptidase C01.098: CPC peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

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    2016
  1. Ettari,R., Previti,S., Tamborini,L., Cullia,G., Grasso,S. and Zappala,M.
    The inhibition of cysteine proteases rhodesain and TbCatB: a valuable approach to treat human African trypanosomiasis
    Mini Rev Med Chem16, 1374-1391. PubMed  Europe PubMed DOI  V  I
  2. Schad,C., Baum,U., Frank,B., Dietzel,U., Mattern,F., Gomes,C., Ponte-Sucre,A., Moll,H., Schurigt,U. and Schirmeister,T.
    Development of a new antileishmanial aziridine-2,3-dicarboxylate-based inhibitor with high selectivity for parasite cysteine proteases
    Antimicrob Agents Chemother60, 797-805. PubMed  Europe PubMed DOI  I
  3. 2010
  4. Mallari,J.P., Zhu,F., Lemoff,A., Kaiser,M., Lu,M., Brun,R. and Guy,R.K.
    Optimization of purine-nitrile TbcatB inhibitors for use in vivo and evaluation of efficacy in murine models
    Bioorg Med Chem18, 8302-8309. PubMed  Europe PubMed DOI  I
  5. Mott,B.T., Ferreira,R.S., Simeonov,A., Jadhav,A., Ang,K.K., Leister,W., Shen,M., Silveira,J.T., Doyle,P.S., Arkin,M.R., McKerrow,J.H., Inglese,J., Austin,C.P., Thomas,C.J., Shoichet,B.K. and Maloney,D.J.
    Identification and optimization of inhibitors of trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB
    J Med Chem53, 52-60. PubMed  Europe PubMed DOI  S  I
  6. 2009
  7. Caffrey,C.R. and Steverding,D.
    Kinetoplastid papain-like cysteine peptidases
    Mol Biochem Parasitol167, 12-19. PubMed  Europe PubMed DOI  I
  8. Mallari,J.P., Shelat,A.A., Kosinski,A., Caffrey,C.R., Connelly,M., Zhu,F., McKerrow,J.H. and Guy,R.K.
    Structure-guided development of selective TbcatB inhibitors
    J Med Chem52, 6489-6493. PubMed  Europe PubMed DOI  I
  9. 2008
  10. Mallari,J.P., Shelat,A.A., Obrien,T., Caffrey,C.R., Kosinski,A., Connelly,M., Harbut,M., Greenbaum,D., McKerrow,J.H. and Guy,R.K.
    Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB
    J Med Chem51, 545-552. PubMed  Europe PubMed DOI  I
  11. Mallari,J.P., Shelat,A., Kosinski,A., Caffrey,C.R., Connelly,M., Zhu,F., McKerrow,J.H. and Guy,R.K.
    Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB
    Bioorg Med Chem Lett18, 2883-2885. PubMed  Europe PubMed DOI  I
  12. 2003
  13. Chibale,K. and Musonda,C.C.
    The synthesis of parasitic cysteine protease and trypanothione reductase inhibitors
    Curr Med Chem10, 1863-1889. PubMed  Europe PubMed DOI  I
  14. Gantt,K.R., Schultz-Cherry,S., Rodriguez,N., Jeronimo,S.M., Nascimento,E.T., Goldman,T.L., Recker,T.J., Miller,M.A. and Wilson,M.E.
    Activation of TGF-beta by Leishmania chagasi: importance for parasite survival in macrophages
    J Immunol170, 2613-2620. PubMed  Europe PubMed  I
  15. 1999
  16. [YEAR:15-5-1999]Chan,V.J., Selzer,P.M., McKerrow,J.H. and Sakanari,J.A.
    Expression and alteration of the S2 subsite of the Leishmania major cathepsin B-like cysteine protease
    Biochem J340, 113-117. PubMed  Europe PubMed  I