Literature for peptidase C01.062: cathepsin B-like peptidase (platyhelminth)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(References are filtered for relevance to Inhibitor. To remove the filter click here. See explanation.)

    2024
  1. Fuchs,N., Zimmermann,R.A., Schwickert,M., Gunkel,A., Zimmer,C., Meta,M., Schwickert,K., Keiser,J., Haeberli,C., Kiefer,W. and Schirmeister,T.
    Dual Strategy to Design New Agents Targeting Schistosoma mansoni: Advancing Phenotypic and SmCB1 Inhibitors for Improved Efficacy
    ACS Infect Dis10, 1664-1678. PubMed  Europe PubMed DOI  I
  2. Spiwokova,P., Horn,M., Fanfrlik,J., Jilkova,A., Fajtova,P., Leontovyc,A., Houstecka,R., Bielikova,L., Brynda,J., Chanova,M., Mertlikova-Kaiserova,H., Caro-Diaz,E.J.E., Almaliti,J., El-Sakkary,N., Gerwick,W.H., Caffrey,C.R. and Mares,M.
    Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis
    ACS Infect Dis10, 1935-1948. PubMed  Europe PubMed DOI  I
  3. 2020
  4. Jilkova,A., Horn,M. and Mares,M.
    Structural and functional characterization of Schistosoma mansoni cathepsin B1
    Methods Mol Biol2151, 145-158. PubMed  Europe PubMed DOI  E  S  I
  5. 2015
  6. Fonseca,N.C., da Cruz,L.F., da Silva Villela,F., do Nascimento Pereira,G.A., de Siqueira-Neto,J.L., Kellar,D., Suzuki,B.M., Ray,D., de Souza,T.B., Alves,R.J., Junior,P.A., Romanha,A.J., Murta,S.M., McKerrow,J.H., Caffrey,C.R., de Oliveira,R.B. and Ferreira,R.S.
    Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1
    Antimicrob Agents Chemother59, 2666-2677. PubMed  Europe PubMed DOI  I
  7. 2013
  8. Fanfrlik,J., Brahmkshatriya,P.S., Rezac,J., Jilkova,A., Horn,M., Mares,M., Hobza,P. and Lepsik,M.
    Quantum mechanics-based scoring rationalizes the irreversible inactivation of parasitic Schistosoma mansoni cysteine peptidase by vinyl sulfone inhibitors
    J Phys Chem B117, 14973-14982. PubMed  Europe PubMed DOI  I