$VAR1 = undef;

Summary for peptidase S08.052: cerevisin

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Namecerevisin
Other namesalkaline proteinase (Penicillium citrinum), allergen Pen c 2 (Penicillium citrinum), allergen Rho m 2 (Rhodotorula mucilaginosa), antigen Pen c 2 (Penicillium citrinum), antigen Pen o 18 (Penicillium oxalicum), antigen Pen c 18 (Penicillium citrinum), antigen Pen ch 18 (Penicillium chrysogenum), Evsp peptidase (Esteya vermicola), Isp6 protein (Schizosaccharomyces pombe), PRB1 g.p. (Saccharomyces cerevisiae), proteinase yscB (Saccharomyces cerevisiae), proteinase B (Saccharomyces cerevisiae), Psp1 g.p. (Pyrenopeziza brassicae), SPMI g.p. (Magnaporthe grisea), SL41 g.p. (Trichoderma harzianum)
Domain architecture
MEROPS Classification
Classification Clan SB >> Subclan (none) >> Family S8 >> Subfamily A >> S08.052
Holotypecerevisin (Saccharomyces cerevisiae), Uniprot accession P09232 (peptidase unit: 269-635), MERNUM MER0000356
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeSerine
PeplistIncluded in the Peplist with identifier PL00352
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.21 (Serine endopeptidases) >> Peptidase 3.4.21.48
EnzymologyBRENDA database
Proteolytic eventsCutDB database (9 cleavages)
PhysiologyProcesses precursors of other proteins in yeast vacuole.
Other databases PANTHERhttp://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR43806:SF25
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/rlyScissile bond-/-/-/- (based on 21 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 1 3 2 0 1 0 1 2
Pro 0 0 0 0 0 0 1 1
Ala 1 2 1 0 1 3 1 0
Val 1 1 0 0 2 1 1 0
Leu 3 1 1 4 1 2 0 1
Ile 1 0 1 0 0 0 0 0
Met 0 0 2 0 0 0 0 0
Phe 1 0 1 2 3 1 1 0
Tyr 0 0 1 4 2 1 0 2
Trp 1 2 0 0 0 0 0 0
Ser 0 1 1 0 0 0 0 0
Thr 0 1 0 0 0 1 1 0
Cys 0 1 0 0 0 0 0 0
Asn 0 0 1 0 0 0 1 0
Gln 0 1 0 1 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 2 2 1 0 1 1 0 1
Lys 0 0 2 2 0 0 0 2
Arg 2 1 1 8 0 0 1 0
His 0 0 1 0 1 1 0 0