$VAR1 = undef;

Summary for peptidase M24.003: Xaa-Pro dipeptidase (bacteria-type)

MEROPS Classification
Classification	Clan MG >> Subclan (none) >> Family M24 >> Subfamily B >> M24.003
Holotype	Xaa-Pro dipeptidase (bacteria-type) (Escherichia coli), Uniprot accession P21165 (peptidase unit: 157-443), MERNUM MER0001250
History	Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.

Activity
Catalytic type	Metallo
Peplist	Included in the Peplist with identifier PL00238
NC-IUBMB	Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.13 (Dipeptidases) >> Peptidase 3.4.13.9
Enzymology	BRENDA database
Physiology	Degrades proline-containing peptides, e.g. from collagen.
Other databases	PANTHER	http://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR43226:SF2
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/-/-P/-/-/- (based on 13 cleavages)

Specificity matrix

Amino acid P4 P3 P2 P1 P1' P2' P3' P4' Gly 0 0 0 1 0 0 0 0 Pro 0 0 0 1 13 0 0 0 Ala 0 0 0 1 0 0 0 0 Val 0 0 0 1 0 0 0 0 Leu 0 0 0 1 0 0 0 0 Ile 0 0 0 1 0 0 0 0 Met 0 0 0 1 0 0 0 0 Phe 0 0 0 1 0 0 0 0 Tyr 0 0 0 1 0 0 0 0 Trp 0 0 0 0 0 0 0 0 Ser 0 0 0 1 0 0 0 0 Thr 0 0 0 0 0 0 0 0 Cys 0 0 0 0 0 0 0 0 Asn 0 0 0 0 0 0 0 0 Gln 0 0 0 0 0 0 0 0 Asp 0 0 0 0 0 0 0 0 Glu 0 0 0 0 0 0 0 0 Lys 0 0 0 1 0 0 0 0 Arg 0 0 0 1 0 0 0 0 His 0 0 0 1 0 0 0 0

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