Substrates for peptidase M24.003: Xaa-Pro dipeptidase (bacteria-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Ala-Pro Ala+Pro S - - - Ala Pro - - - Park et al., 2004
Arg-Pro Arg+Pro S - - - Arg Pro - - - Park et al., 2004
Gly-Pro Gly+Pro S - - - Gly Pro - - - Park et al., 2004
His-Pro His+Pro S - - - His Pro - - - Park et al., 2004
Ile-Pro Ile+Pro S - - - Ile Pro - - - Park et al., 2004
Leu-Pro Leu+Pro S - - - Leu Pro - - - Park et al., 2004
Lys-Pro Lys+Pro S - - - Lys Pro - - - Park et al., 2004
Met-Pro Met+Pro S - - - Met Pro - - - Park et al., 2004
Phe-Pro Phe+Pro S - - - Phe Pro - - - Park et al., 2004
Pro-Pro Pro+Pro S - - - Pro Pro - - - Park et al., 2004
Ser-Pro Ser+Pro S - - - Ser Pro - - - Park et al., 2004
Tyr-Pro Tyr+Pro S - - - Tyr Pro - - - Park et al., 2004
Val-Pro Val+Pro S - - - Val Pro - - - Park et al., 2004