$VAR1 = undef;

Summary for peptidase M16.011: falcilysin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS Namefalcilysin
Other namesmetalloendopeptidase (Plasmodium falciparum)
Domain architecture
MEROPS Classification
Classification Clan ME >> Subclan (none) >> Family M16 >> Subfamily C >> M16.011
Holotypefalcilysin (Plasmodium falciparum) (peptidase unit: 121-583), MERNUM MER0015088
History Identifier created: MEROPS 5.1 (22 June 2000)
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (7 cleavages)
Other databases PANTHERhttp://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR43016:SF3
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/k/kdlScissile bond-/-/-/- (based on 10 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 1 0 0 0 1 0 0 1
Pro 0 0 0 0 0 0 2 0
Ala 3 2 0 0 0 0 2 0
Val 0 1 1 0 1 1 1 0
Leu 2 1 0 2 1 1 2 0
Ile 1 0 0 0 0 1 0 0
Met 0 0 0 0 0 1 0 0
Phe 0 1 0 0 1 2 0 0
Tyr 0 1 0 0 1 0 0 0
Trp 1 0 0 0 0 0 0 0
Ser 0 0 2 0 0 1 1 1
Thr 1 2 0 1 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 1 1 2
Gln 0 0 2 0 1 0 0 1
Asp 0 0 0 2 2 0 0 1
Glu 0 0 0 0 0 0 1 0
Lys 0 1 3 4 1 0 0 2
Arg 0 0 0 1 1 2 0 0
His 1 1 2 0 0 0 0 2