$VAR1 = undef;
Summary for peptidase M15.011: vanX D-Ala-D-Ala dipeptidase
| Names | |
|---|---|
| MEROPS Name | vanX D-Ala-D-Ala dipeptidase |
| Other names | VanX g.p. (Enterococcus faecium) |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan MD >> Subclan (none) >> Family M15 >> Subfamily D >> M15.011 |
| Holotype | vanX D-Ala-D-Ala dipeptidase (Enterococcus faecium), Uniprot accession Q06241 (peptidase unit: 50-189), MERNUM MER0001602 |
| History | Identifier created: MEROPS 5.5 (16 June 2001) |
| Activity | |||
|---|---|---|---|
| Catalytic type | Metallo | ||
| Peplist | Included in the Peplist with identifier PL00219 | ||
| NC-IUBMB | Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.13 (Dipeptidases) >> Peptidase 3.4.13.22 | ||
| Enzymology | BRENDA database | ||
| Pharmaceutical relevance | Necessary for the resistance of some pathogenic bacteria to vancomycin, and hence a target for antibacterial drugs (Arthur et al., 1998). | ||
