$VAR1 = undef;

Summary for peptidase M03.004: oligopeptidase A

Names
MEROPS Name	oligopeptidase A
Other names	OpdA g.p. (Escherichia coli), prlC g.p. (Escherichia coli), proteinase In

Domain architecture

MEROPS Classification
Classification	Clan MA >> Subclan MA(E) >> Family M3 >> Subfamily A >> M03.004
Holotype	oligopeptidase A (Salmonella typhimurium), Uniprot accession P27237 (peptidase unit: 1-680), MERNUM MER0001161
History	Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.

Activity
Catalytic type	Metallo
Peplist	Included in the Peplist with identifier PL00139
NC-IUBMB	Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.24 (Metalloendopeptidases) >> Peptidase 3.4.24.70
Enzymology	BRENDA database
Proteolytic events	CutDB database (1 cleavage)
Physiology	Degradation of lipoprotein signal peptides, and other Intracellular oligopeptides. Role in maturation of bacteriophage P22 gp7 precursor.
Other databases	PANTHER	http://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR11804:SF8
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/a/P/--/-/-/- (based on 10 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	1	0	1	2	1	1	0
Pro	0	0	6	0	0	2	0	0
Ala	3	3	0	3	0	0	2	0
Val	0	2	0	0	0	2	0	0
Leu	0	0	1	1	2	0	0	0
Ile	0	0	0	0	0	0	0	0
Met	0	0	0	0	0	0	0	0
Phe	0	0	0	1	0	0	0	0
Tyr	0	1	0	0	0	0	1	0
Trp	0	0	0	0	0	0	0	0
Ser	1	0	0	0	0	0	0	0
Thr	0	0	0	0	0	0	0	0
Cys	0	0	0	0	0	0	0	0
Asn	0	0	0	0	0	0	0	0
Gln	0	0	0	0	0	0	0	0
Asp	0	0	0	0	0	0	0	0
Glu	0	0	0	1	0	0	0	0
Lys	0	0	0	2	1	0	0	1
Arg	0	0	0	1	0	0	0	0
His	0	0	0	0	0	0	0	0