Substrates for peptidase M03.004: oligopeptidase A

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Boc-Val-Leu-Lys-NHMec Boc-Val-Leu-Lys+NHMec S Boc Val Leu Lys AMC - - - Miller, 2004
Boc-Val-Pro-Arg-NHMec Boc-Val-Pro-Arg+NHMec S Boc Val Pro Arg AMC - - - Miller, 2004
FA-Ala-Leu-Val FA-Ala+Leu-Val S - - FA Ala Leu Val - - Marokházi et al., 2004
FA-Ala-Leu-Val-Tyr FA-Ala+Leu-Val-Tyr S - - FA Ala Leu Val Tyr - Marokházi et al., 2004
FA-Leu-Gly-Pro-Ala FA-Leu+Gly-Pro-Ala S - - FA Leu Gly Pro Ala - Marokházi et al., 2004
gp7 protein Q01074 1-229 peptide-Glu20+Lys-peptide N Ser Tyr Pro Glu Lys Gly Gly Lys Miller, 2004 16435
Suc-Ala-Ala-Pro-Ala-NHMec Suc-Ala-Ala-Pro-Ala+NHMec S Ala Ala Pro Ala AMC - - - Marokházi et al., 2004
Suc-Ala-Ala-Pro-Lys-NHMec Suc-Ala-Ala-Pro-Lys+NHMec S Ala Ala Pro Lys AMC - - - Marokházi et al., 2004
Suc-Ala-Ala-Pro-Phe-NHMec Suc-Ala-Ala-Pro-Phe+NHMec S Ala Ala Pro Phe AMC - - - Marokházi et al., 2004
Z-Gly-Pro-Gly-Gly-Pro-Ala Z-Gly-Pro-Gly+Gly-Pro-Ala S Z Gly Pro Gly Gly Pro Ala - Miller, 2004