$VAR1 = undef;

Summary for peptidase C48.007: SENP2 peptidase

Names
MEROPS Name	SENP2 peptidase
Other names	sentrin-specific peptidase 2, KIAA1331 protein, SuPr-1 protein, SUMO-specific peptidase 2

Domain architecture

MEROPS Classification
Classification	Clan CE >> Subclan (none) >> Family C48 >> Subfamily (none) >> C48.007
Holotype	SENP2 peptidase (Homo sapiens), Uniprot accession Q9HC62 (peptidase unit: 401-560), MERNUM MER0012183
History	Identifier created: MEROPS 5.3 (4 December 2000)

Activity
Catalytic type	Cysteine
NC-IUBMB	Not yet included in IUBMB recommendations.
Activity status	human: active (active (by similarity to ) mouse: active (Nishida et al., 2001)
Pathways	KEGG	RNA transport
	KEGG	Wnt signaling pathway
Other databases	TREEFAM	http://www.treefam.org/family/TF316289
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	Q/T/G/GKv/-/ea/- (based on 20 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	0	20	20	0	0	0	0
Pro	0	0	0	0	0	2	1	0
Ala	0	0	0	0	0	0	3	1
Val	0	0	0	0	4	0	0	1
Leu	0	0	0	0	0	2	0	0
Ile	0	0	0	0	0	0	0	1
Met	0	0	0	0	0	1	0	0
Phe	0	0	0	0	0	0	1	0
Tyr	0	3	0	0	0	2	0	0
Trp	0	0	0	0	0	0	0	0
Ser	0	0	0	0	0	1	0	4
Thr	0	17	0	0	0	1	1	0
Cys	0	0	0	0	0	1	0	0
Asn	0	0	0	0	0	0	0	1
Gln	20	0	0	0	0	1	0	0
Asp	0	0	0	0	0	0	0	0
Glu	0	0	0	0	0	2	6	2
Lys	0	0	0	0	10	0	0	1
Arg	0	0	0	0	0	0	0	1
His	0	0	0	0	1	1	0	0