$VAR1 = undef;

Summary for peptidase C19.022: ubiquitin-specific peptidase 15

Names
MEROPS Name	ubiquitin-specific peptidase 15
Other names	deubiquitinating enzyme Ubp109, KIAA0529 protein, ubiquitin-specific protease 15, USP15 g.p. (Homo sapiens)

Domain architecture

MEROPS Classification
Classification	Clan CA >> Subclan (none) >> Family C19 >> Subfamily (none) >> C19.022
Holotype	ubiquitin-specific peptidase 15 (Homo sapiens), Uniprot accession Q9Y4E8 (peptidase unit: 251-944), MERNUM MER0005427
History	Identifier created: MEROPS 3.4 (5 November 1999)

Activity
Catalytic type	Cysteine
NC-IUBMB	Not yet included in IUBMB recommendations.
Proteolytic events	CutDB database (1 cleavage)
Activity status	human: active (Baker et al., 1999) mouse: active (Angelats et al. (2003))
Other databases	TREEFAM	http://www.treefam.org/family/TF106276
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	L/R/G/GM/h/g/s (based on 10 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	0	10	10	0	0	4	0
Pro	0	0	0	0	1	2	1	0
Ala	0	0	0	0	1	0	0	0
Val	0	0	0	0	0	1	0	0
Leu	10	0	0	0	0	0	0	0
Ile	0	0	0	0	0	0	1	0
Met	0	0	0	0	6	0	0	0
Phe	0	0	0	0	0	0	0	1
Tyr	0	0	0	0	0	0	1	1
Trp	0	0	0	0	0	0	0	0
Ser	0	0	0	0	0	0	0	4
Thr	0	0	0	0	0	0	0	1
Cys	0	0	0	0	0	0	0	0
Asn	0	0	0	0	0	0	0	0
Gln	0	0	0	0	0	1	0	0
Asp	0	0	0	0	0	0	0	0
Glu	0	0	0	0	0	0	0	0
Lys	0	0	0	0	1	0	0	0
Arg	0	10	0	0	1	0	0	0
His	0	0	0	0	0	3	0	0