$VAR1 = undef;

Summary for peptidase C14.019: caspase DRONC (Drosophila melanogaster)

Names
MEROPS Name	caspase DRONC (Drosophila melanogaster)
Other names	caspase Nc (Drosophila melanogaster), Nc protein (Drosophila melanogaster)

Domain architecture

MEROPS Classification
Classification	Clan CD >> Subclan (none) >> Family C14 >> Subfamily A >> C14.019
Holotype	caspase DRONC (Drosophila melanogaster), Uniprot accession Q9XYF4 (peptidase unit: 154-447), MERNUM MER0005247
History	Identifier created: MEROPS 3.30 (20 July 1999)

Activity
Catalytic type	Cysteine
Peplist	Included in the Peplist with identifier PL00431
NC-IUBMB	Not yet included in IUBMB recommendations.
Proteolytic events	CutDB database (1 cleavage)
Other databases	PANTHER	http://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR10454:SF202
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	d/Eq/tv/D-/-/-/- (based on 11 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	0	0	0	1	0	1	0
Pro	0	0	1	0	0	0	0	1
Ala	0	0	1	0	1	0	0	0
Val	2	1	2	0	0	0	0	0
Leu	0	0	0	0	0	1	0	0
Ile	2	0	1	0	0	0	0	0
Met	0	0	0	0	0	0	0	0
Phe	0	0	0	0	0	0	0	0
Tyr	1	0	0	0	0	0	0	0
Trp	1	0	0	0	0	0	0	0
Ser	0	0	0	0	0	0	1	2
Thr	2	0	5	0	1	0	0	0
Cys	0	0	0	0	0	1	0	0
Asn	0	0	0	0	0	0	0	0
Gln	0	2	0	0	0	0	0	0
Asp	3	0	0	9	0	1	0	0
Glu	0	7	0	2	0	0	0	0
Lys	0	0	0	0	0	0	0	0
Arg	0	0	0	0	0	0	1	0
His	0	1	1	0	0	0	0	0