$VAR1 = undef;

Summary for peptidase C01.006: ficin

Names
MEROPS Name	ficin
Other names	ficain, ficin E

MEROPS Classification
Classification	Clan CA >> Subclan (none) >> Family C1 >> Subfamily A >> C01.006
Holotype	ficin (Ficus glabrata) (peptidase unit: 1-12), MERNUM MER0001982
History	Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.

Activity
Catalytic type	Cysteine
Peplist	Included in the Peplist with identifier PL00051
NC-IUBMB	Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.22 (Cysteine endopeptidases) >> Peptidase 3.4.22.3
Enzymology	BRENDA database
Biotechnology	Laboratory reagent in blood group determination.
Pharmaceutical relevance	Potential use for elimination of gastrointestinal parasites.
Other databases	WIKIPEDIA	http://en.wikipedia.org/wiki/Ficain
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/fl/--/-/-/- (based on 17 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	1	2	1	0	0	0	1
Pro	1	0	0	0	0	0	1	2
Ala	0	1	0	1	0	0	1	0
Val	0	1	2	0	0	1	1	1
Leu	2	1	3	1	2	2	1	0
Ile	0	1	0	0	0	0	0	0
Met	0	0	0	0	0	0	0	0
Phe	0	2	6	2	1	0	0	0
Tyr	0	0	0	1	1	1	0	0
Trp	0	0	0	0	0	0	0	0
Ser	1	0	0	2	2	0	1	0
Thr	0	1	1	0	1	2	1	0
Cys	0	0	0	0	0	0	0	0
Asn	0	0	0	0	0	1	0	1
Gln	0	0	0	1	0	0	0	0
Asp	0	0	0	0	0	0	0	1
Glu	2	0	0	0	0	0	1	2
Lys	1	0	1	2	1	1	1	1
Arg	1	1	0	5	0	0	0	0
His	1	1	0	1	1	1	0	0