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Literature for peptidase C01.006: ficin

Summary Alignment Sequences Sequence features Distribution Literature Substrates

(Topics flags: P Specificity, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2022
  1. Bruce,B.
    Enzyme treatment of red blood cells: use of ficin and papain
    Immunohematology38, 90-95. PubMed  Europe PubMed DOI  V
    2. 2020
  2. Filippova,I.Y., Dvoryakova,E.A., Sokolenko,N.I., Simonyan,T.R., Tereshchenkova,V.F., Zhiganov,N.I., Dunaevsky,Y.E., Belozersky,M.A., Oppert,B. and Elpidina,E.N.
    New Glutamine-Containing Substrates for the Assay of Cysteine Peptidases From the C1 Papain Family
    Front Mol Biosci7, 578758-578758. PubMed  Europe PubMed DOI
  3. Hamed,M.B., El-Badry,M.O., Kandil,E.I., Borai,I.H. and Fahmy,A.S.
    A contradictory action of procoagulant ficin by a fibrinolytic serine protease from Egyptian Ficus carica latex
    Biotechnol Rep (Amst)27, e00492-e00492. PubMed  Europe PubMed DOI
  4. Nishimura,K., Higashiya,K., Ueshima,N., Abe,T. and Yasukawa,K.
    Characterization of proteases activities in Ficus carica cultivars
    J Food Sci85, 535-544. PubMed  Europe PubMed DOI
  5. Sattari,F., Rigi,G. and Ghaedmohammadi,S.
    The first report on molecular cloning, functional expression, purification, and statistical optimization of Escherichia coli-derived recombinant Ficin from Iranian fig tree (Ficus carica cv.Sabz)
    Int J Biol Macromol165, 2126-2135. PubMed  Europe PubMed DOI
    6. 2019
  6. Milosevic,J., Jankovic,B., Prodanovic,R. and Polovic,N.
    Comparative stability of ficin and papain in acidic conditions and the presence of ethanol
    Amino Acids51, 829-838. PubMed  Europe PubMed DOI
  7. Pan,Y., Pang,Y., Shi,Y., Zheng,W., Long,Y., Huang,Y. and Zheng,H.
    One-pot synthesis of a composite consisting of the enzyme ficin and a zinc(II)-2-methylimidazole metal organic framework with enhanced peroxidase activity for colorimetric detection for glucose
    Mikrochim Acta186, 213-213. PubMed  Europe PubMed DOI
    8. 2018
  8. Pan,Y., Yang,Y., Pang,Y., Shi,Y., Long,Y. and Zheng,H.
    Enhancing the peroxidase-like activity of ficin via heme binding and colorimetric detection for uric acid
    Talanta185, 433-438. PubMed  Europe PubMed DOI
  9. Shabani,R., Shahidi,S.A. and Rafe,A.
    Rheological and structural properties of enzyme-induced gelation of milk proteins by ficin and Polyporus badius
    Food Sci Nutr6, 287-294. PubMed  Europe PubMed DOI
  10. Wanderley,L.F., Soares,A.M.D.S., Silva,C.R.E., Figueiredo,I.M., Ferreira,A.T.D.S., Perales,J., Mota,H.R.O., Oliveira,J.T.A. and Costa Junior,L.M.
    A cysteine protease from the latex of Ficus benjamina has in vitro anthelmintic activity against Haemonchus contortus
    Rev Bras Parasitol Vet27, 473-480. PubMed  Europe PubMed DOI
    11. 2017
  11. Baidamshina,D.R., Trizna,E.Y., Holyavka,M.G., Bogachev,M.I., Artyukhov,V.G., Akhatova,F.S., Rozhina,E.V., Fakhrullin,R.F. and Kayumov,A.R.
    Targeting microbial biofilms using ficin, a nonspecific plant protease
    Sci Rep7, 46068-46068. PubMed  Europe PubMed DOI
  12. Yang,Y., Shen,D., Long,Y., Xie,Z. and Zheng,H.
    Intrinsic Peroxidase-like Activity of Ficin
    Sci Rep7, 43141-43141. PubMed  Europe PubMed DOI
    13. 2016
  13. Raskovic,B., Lazic,J. and Polovic,N.
    Characterisation of general proteolytic, milk clotting and antifungal activity of Ficus carica latex during fruit ripening
    J Sci Food Agric96, 576-582. PubMed  Europe PubMed DOI
  14. Zare,H., Moosavi-Movahedi,A.A., Salami,M., Sheibani,N., Khajeh,K. and Habibi-Rezaei,M.
    Autolysis control and structural changes of purified ficin from Iranian fig latex with synthetic inhibitors
    Int J Biol Macromol84, 464-471. PubMed  Europe PubMed DOI
    15. 2015
  15. Baeyens-Volant,D., Matagne,A., El Mahyaoui,R., Wattiez,R. and Azarkan,M.
    A novel form of ficin from Ficus carica latex: purification and characterization
    Phytochemistry117, 154-167. PubMed  Europe PubMed DOI
  16. Haesaerts,S., Rodriguez Buitrago,J.A., Loris,R., Baeyens-Volant,D. and Azarkan,M.
    Crystallization and preliminary X-ray analysis of four cysteine proteases from Ficus carica latex
    Acta Crystallogr Sect F Struct Biol Commun71, 459-465. PubMed  Europe PubMed DOI
    17. 2013
  17. Zare,H., Moosavi-Movahedi,A.A., Salami,M., Mirzaei,M., Saboury,A.A. and Sheibani,N.
    Purification and autolysis of the ficin isoforms from fig (Ficus carica cv. Sabz) latex
    Phytochemistry87, 16-22. PubMed  Europe PubMed DOI
    18. 2012
  18. Singleton,A. and Buttle,D.J.
    Ficain
    [ISSN:978-0-12-407743-0]3, 1877-1879. DOI
    19. 2011
  19. Azarkan,M., Matagne,A., Wattiez,R., Bolle,L., Vandenameele,J. and Baeyens-Volant,D.
    Selective and reversible thiol-pegylation, an effective approach for purification and characterization of five fully active ficin (iso)forms from Ficus carica latex
    Phytochemistry72, 1718-1731. PubMed  Europe PubMed DOI
  20. Pourmorad,F., Honary,S., Azadbakht,M., Asgarirad,H. and Golmohammadzadeh,G.
    Separation of proteolytic components of Iran Ficus carica latex by column chromatography and electrophoresis and latex anti-corn activity
    Intl J Pharm Sci Rev Res7, 83-85.  U
    21. 2010
  21. Reddy,V.B. and Lerner,E.A.
    Plant cysteine proteases that evoke itch activate protease-activated receptors
    Br J Dermatol163, 532-535. PubMed  Europe PubMed DOI
    22. 2009
  22. Devaraj,K.B., Kumar,P.R. and Prakash,V.
    Characterization of acid-induced molten globule like state of ficin
    Int J Biol Macromol45, 248-254. PubMed  Europe PubMed DOI
    23. 2008
  23. Devaraj,K.B., Kumar,P.R. and Prakash,V.
    Purification, characterization, and solvent-induced thermal stabilization of ficin from Ficus carica
    J Agric Food Chem56, 11417-11423. PubMed  Europe PubMed DOI
  24. Huang,L., Qu,H.Z., Zhang,L., Du,S.S., Yang,S., Hao,D.Y. and Wang,X.P.
    Purification and characterization of a proteolytic enzyme from fig latex
    Chemical Research in Chinese Universities24, 348-352. DOI
  25. Sekizaki,H., Toyota,E., Fuchise,T., Zhou,S., Noguchi,Y. and Horita,K.
    Application of several types of substrates to ficin-catalyzed peptide synthesis
    Amino Acids34, 149-153. PubMed  Europe PubMed DOI
    26. 2007
  26. Yamamoto,N., Nakayama,A., Oshima,M., Kawasaki,N. and Aiba,S.
    Enzymatic hydrolysis of lysine diisocyanate based polyurethanes and segmented polyurethane ureas by various proteases
    React Funct Polym67, 1338-1345. DOI
    27. 2004
  27. Buttle,D.J.
    Ficain
    [ISSN:0-12-079610-4]2, 1141-1142.  V
    28. 1995
  28. Hansler,M., Ullmann,G. and Jakubke,H.D.
    The application of papain, ficin and clostripain in kinetically controlled peptide synthesis in frozen aqueous solutions
    J Pept Sci1, 283-287. PubMed  Europe PubMed DOI
    29. 1994
  29. Lopez,L.M.I., Natalucci,C.L., Priolo,N.S., Arribere,M.C. and Caffini,N.O.
    Proteases of higher plants. II. Ficin (EC 3.4.22.3)
    Acta Farm Bonaer13, 123-131.
    30. 1992
  30. Patel,M., Kayani,I.S., Mellor,G.W., Sreedharan,S., Templeton,W., Thomas,E.W., Thomas,M. and Brocklehurst,K.
    Variation in the P2-S2 stereochemical selectivity towards the enantiomeric N-acetylphenylalanylglycine 4-nitroanilides among the cysteine proteinases papain, ficin and actinidin
    Biochem J281, 553-559. PubMed  Europe PubMed
    31. 1986
  31. Hansson,A., Veliz,G., Naquira,C., Amren,M., Arroyo,M. and Arevalo,G.
    Preclinical and clinical studies with latex from Ficus glabrata HBK, a traditional intestinal anthelminthic in the Amazonian area
    J Ethnopharmacol17, 105-138. PubMed  Europe PubMed
    32. 1985
  32. [YEAR:29-1-1985]Asboth,B., Stokum,E., Khan,I.U. and Polgar,L.
    Mechanism of action of cysteine proteinases: oxyanion binding site is not essential in the hydrolysis of specific substrates
    Biochemistry24, 606-609. PubMed  Europe PubMed
    33. 1984
  33. Carotti,A., Casini,G. and Hansch,C.
    Structure-activity relationship of the ficin hydrolysis of phenyl hippurates. Comparison with papain, actinidin, and bromelain
    J Med Chem27, 1427-1431. PubMed  Europe PubMed  P
    34. 1983
  34. Carey,P.R., Ozaki,Y. and Storer,A.C.
    Comparison of the substrate conformations in the active sites of papain, chymopapain, ficin and bromelain by resonance Raman spectroscopy
    Biochem Biophys Res Commun117, 725-731. PubMed  Europe PubMed
  35. Lynn,K.R.
    Definition of the site of reactivity of the ancestral protease of the papain type
    Phytochemistry22, 2485-2487. DOI  P
    36. 1982
  36. Brocklehurst,K., Mushiri,S.M., Patel,G. and Willenbrock,F.
    Evidence for a close similarity in the catalytic sites of papain and ficin in near-neutral media despite differences in acidic and alkaline media. Kinetics of the reactions of papain and ficin with chloroacetate
    Biochem J201, 101-104. PubMed  Europe PubMed
    37. 1976
  37. Gaughran,E.R.L.
    Ficin: history and present status
    Q J Crude Drug Res14, 1-21.
  38. Malthouse,J.P. and Brocklehurst,K.
    Preparation of fully active ficin from Ficus glabrata by covalent chromatography and characterization of its active centre by using 2,2'-dipyridyl disulphide as a reactivity probe
    Biochem J159, 221-234. PubMed  Europe PubMed
    39. 1975
  39. Shipton,M., Kierstan,M.P.J., Malthouse,J.P.G., Stuchbury,T. and Brocklehurst,K.
    The case for assigning a value of approximately 4 to pKa(I) of the essential histidine cysteine interactive systems of papain, bromelain and ficin
    FEBS Lett50, 365-368. PubMed  Europe PubMed DOI
    40. 1974
  40. Anderson,C.D. and Hall,P.L.
    Purification of ficin by affinity chromatography
    Anal Biochem60, 417-423. PubMed  Europe PubMed
    41. 1973
  41. Gleisner,J.M. and Liener,I.E.
    Chemical modification of the histidine residue located at the active site of ficin
    Biochim Biophys Acta317, 482-491. PubMed  Europe PubMed
  42. Mamoru,S., Masanori,S. and Chiaki,M.
    Studies on proteinases from Ficus carica var. Horaishi IV. Kininase action of ficin A, B, C and D
    Nihon Yakurigaku Zasshi69, 409-417. DOI  P
    43. 1970
  43. Husain,S.S. and Lowe,G.
    The amino acid sequence around the active-site cysteine and histidine residues, and the buried cysteine residue in ficin
    Biochem J117, 333-340. PubMed  Europe PubMed
    44. 1969
  44. Whitaker,J.R.
    Papain- and ficin-catalyzed reactions. Effect of pH on activity and conformation of ficin
    Biochemistry8, 1896-1901. PubMed  Europe PubMed
    45. 1968
  45. Englund,P.T., King,T.P., Craig,L.C. and Walti,A.
    Studies on ficin. I. Its isolation and characterization
    Biochemistry7, 163-175. PubMed  Europe PubMed
  46. Williams,D.C., Sgarbieri,V.C. and Whitaker,J.R.
    Proteolytic activity in the genus Ficus
    Plant Physiol43, 1083-1088. PubMed  Europe PubMed
    47. 1965
  47. Lowe,G. and Williams,A.
    Direct evidence for an acylated thiol as an intermediate in papain- and ficin-catalysed hydrolyses
    Biochem J96, 189-193. PubMed  Europe PubMed
    48. 1964
  48. Lowe,G. and Williams,A.
    Direct evidence for an acylated thiol as an intermediate in papain- and ficin-catalysed hydrolyses of esters
    Proc Chem Soc1964, 140-141.
  49. Sgarbieri,V.C., Gupte,S.M., Kramer,D.E. and Whitaker,J.R.
    Ficus enzymes. I. Separation of the proteolytic enzymes of Ficus carica and Ficus glabrata latices
    J Biol Chem239, 2170-2177. PubMed  Europe PubMed
    50. 1958
  50. Whitaker,J.R.
    The effect of variety and maturity on the proteolytic enzyme content of figs
    J Food Sci23, 371-379. DOI
    51. 1957
  51. Whitaker,J.R.
    Properties of the proteolytic enzymes of commercial ficin
    J Food Sci22, 483-493. DOI
    52. 1938
  52. Walti,A.
    Crystalline ficin
    J Am Chem Soc60, 493-493. DOI
    53. 1930
  53. Robbins,B.H.
    A proteolytic enzyme in ficin, the anthelmintic principle of leche de higueron
    J Biol Chem87, 251-257.

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