$VAR1 = undef;

Summary for peptidase A02.013: bovine leukemia virus retropepsin

Names
MEROPS Name	bovine leukemia virus retropepsin
Other names	retropepsin (bovine leukemia virus)

Domain architecture

MEROPS Classification
Classification	Clan AA >> Subclan (none) >> Family A2 >> Subfamily A >> A02.013
Holotype	bovine leukemia virus retropepsin, Uniprot accession P10270 (peptidase unit: 48-159), MERNUM MER0000981
History	Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.

Activity
Catalytic type	Aspartic
Peplist	Included in the Peplist with identifier PL00034
NC-IUBMB	Not yet included in IUBMB recommendations.
Proteolytic events	CutDB database (3 cleavages)
Physiology	Processing of viral polyprotein.
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	Sp/q/N/YlgP/I/V/Q (based on 20 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	1	0	2	0	0	0	1
Pro	4	0	0	0	16	0	0	1
Ala	0	3	0	1	1	0	0	1
Val	0	1	3	0	1	0	13	0
Leu	1	3	0	6	1	2	1	1
Ile	0	0	2	0	0	15	3	0
Met	0	1	0	1	0	0	0	0
Phe	0	1	0	1	0	0	0	0
Tyr	0	0	0	9	0	0	0	0
Trp	1	0	0	0	0	0	0	0
Ser	13	0	0	0	1	1	0	1
Thr	0	0	0	0	0	1	1	0
Cys	0	0	1	0	0	0	0	0
Asn	1	0	13	0	0	1	0	1
Gln	0	7	1	0	0	0	0	13
Asp	0	0	0	0	0	0	1	0
Glu	0	2	0	0	0	0	1	0
Lys	0	1	0	0	0	0	0	0
Arg	0	0	0	0	0	0	0	0
His	0	0	0	0	0	0	0	0