$VAR1 = undef;
Summary for peptidase A01.018: saccharopepsin
| Names | |
|---|---|
| MEROPS Name | saccharopepsin |
| Other names | allergen Rhi o 1 (Rhizopus oryzae), aspartic proteinase (Neurospora), Neurospora aspartic proteinase, neurosporapepsin, PEP2 g.p. (Aspergillus fumigatus), pep-4 g.p. (Neurospora crassa), PEP4 g.p. (Saccharomyces cerevisiae), peptidase E (Aspergillus fumigatus), Saccharomyces cerevisiae aspartic proteinase, yeast proteinase A, yscA g.p. (Saccharomyces cerevisiae) |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan AA >> Subclan (none) >> Family A1 >> Subfamily A >> A01.018 |
| Holotype | saccharopepsin (Saccharomyces cerevisiae), Uniprot accession P07267 (peptidase unit: 78-405), MERNUM MER0000941 |
| History | Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London. |
| Activity | |||
|---|---|---|---|
| Catalytic type | Aspartic | ||
| Peplist | Included in the Peplist with identifier PL00016 | ||
| NC-IUBMB | Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.23 (Aspartic endopeptidases) >> Peptidase 3.4.23.25 | ||
| Enzymology | BRENDA database | ||
| Proteolytic events | CutDB database (3 cleavages) | ||
| Physiology | Functions in the processing of procerevisin to the active endopeptidase (S08.052) in the vacuolar proteolytic system of Saccharomyces (Van den Hazel et al., 1996). | ||
| Other databases | PANTHER | http://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR13683:SF382 | |
| Cleavage site specificity | Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here. | ||
| Cleavage pattern | -/-/-/- -/-/-/- (based on 14 cleavages) | ||
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| Specificity matrix | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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