Literature for peptidase A01.018: saccharopepsin

(Topics flags: S Structure, A Assay, P Specificity, K Knockout, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2022
1. Juarez-Montiel,M., Clark-Flores,D., Tesillo-Moreno,P., Vega-Camarillo,E., Andrade-Pavon,D., Hernandez-Garcia,J.A., Hernandez-Rodriguez,C. and Villa-Tanaca,L.
   Vacuolar proteases and autophagy in phytopathogenic fungi: A review
   Front Fungal Biol3, 948477-948477. PubMed  Europe PubMed DOI
2019
2. Hu,J., Yu,L., Shu,Q. and Chen,Q.
   Identification of down-regulated proteome in Saccharomyces cerevisiae with the deletion of yeast cathepsin D in response to nitrogen stress
   Microorganisms7, PubMed  Europe PubMed DOI
3. Lu,H., Shu,Q., Lou,H. and Chen,Q.
   Mitochondria-mediated programmed cell death in Saccharomyces cerevisiae induced by betulinic acid is accelerated by the deletion of PEP4 gene
   Microorganisms7, PubMed  Europe PubMed DOI
4. Yoshiya,T., Yamashita,N., Tsuda,S., Oohigashi,K., Masuda,S., Kubodera,T. and Akashi,T.
   HAP-01, the first chromogenic substrate for Aspergillus oryzae acid protease
   Org Biomol Chem17, 776-779. PubMed  Europe PubMed DOI  A
2018
5. Alugoju,P., Janardhanshetty,S.S., Subaramanian,S., Periyasamy,L. and Dyavaiah,M.
   Quercetin protects yeast Saccharomyces cerevisiae pep4 mutant from oxidative and apoptotic stress and extends chronological lifespan
   Curr Microbiol75, 519-530. PubMed  Europe PubMed DOI  I
6. Juarez-Montiel,M., Tesillo-Moreno,P., Cruz-Angeles,A., Soberanes-Gutierrez,V., Chavez-Camarillo,G., Ibarra,J.A., Hernandez-Rodriguez,C. and Villa-Tanaca,L.
   Heterologous expression and characterization of the aspartic endoprotease Pep4um from Ustilago maydis, a homolog of the human cathepsin D, an important breast cancer therapeutic target
   Mol Biol Rep45, 1155-1163. PubMed  Europe PubMed DOI  E
7. Kerstens,W. and Dijck,P.V.
   A Cinderella story: how the vacuolar proteases Pep4 and Prb1 do more than cleaning up the cell's mass degradation processes
   Microb Cell5, 438-443. PubMed  Europe PubMed DOI
2016
8. Sepulveda-Gonzalez,M.E., Parra-Ortega,B., Betancourt-Cervantes,Y., Hernandez-Rodriguez,C., Xicohtencatl-Cortes,J. and Villa-Tanaca,L.
   Vacuolar proteases from Candida glabrata: acid aspartic protease PrA, neutral serine protease PrB and serine carboxypeptidase CpY. The nitrogen source influences their level of expression
   Rev Iberoam Micol33, 26-33. PubMed  Europe PubMed DOI
2015
9. Cai,J., Feng,Y., Dai,Y., Dong,Y., Fan,L., He,G. and Chen,Q.
   [Effect of the deletion of EP4-encoding proteinase A on radioresistance characteristics by S. cerevisiae]
   J Chin Inst Food Sci Technol15, 9-14. DOI  K
10. Sircar,G., Saha,B., Mandal,R.S., Pandey,N., Saha,S. and Gupta Bhattacharya,S.
    Purification, cloning and immuno-biochemical characterization of a fungal aspartic protease allergen Rhi o 1 from the airborne mold Rhizopus oryzae
    PLoS ONE10, e0144547-e0144547. PubMed  Europe PubMed DOI
11. Soberanes-Gutierrez,C.V., Juarez-Montiel,M., Olguin-Rodriguez,O., Hernandez-Rodriguez,C., Ruiz-Herrera,J. and Villa-Tanaca,L.
    The pep4 gene encoding proteinase A is involved in dimorphism and pathogenesis of Ustilago maydis
    Mol Plant Pathol16, 837-846. PubMed  Europe PubMed DOI
2014
12. Bauerova,V., Hajek,M., Pichova,I. and Hruskova-Heidingsfeldova,O.
    Intracellular aspartic proteinase Apr1p of Candida albicans is required for morphological transition under nitrogen-limited conditions but not for macrophage killing
    Folia Microbiol (Praha)59, 485-493. PubMed  Europe PubMed DOI
13. Hecht,K.A., O'Donnell,A.F. and Brodsky,J.L.
    The proteolytic landscape of the yeast vacuole
    Cell Logist4, e28023-e28023. PubMed  Europe PubMed DOI  P
14. Kooij,P.W., Rogowska-Wrzesinska,A., Hoffmann,D., Roepstorff,P., Boomsma,J.J. and Schiott,M.
    Leucoagaricus gongylophorus uses leaf-cutting ants to vector proteolytic enzymes towards new plant substrate
    ISME J8, 1032-1040. PubMed  Europe PubMed DOI
15. Wu,D., Chen,Y., Lu,J., Qi,Y., Zhang,C. and Xiao,D.
    Effect of proteinase A propeptide deletion on its enzyme activity in Saccharomyces cerevisiae
    Lect Notes Electr Eng251 LNEE, 1459-1467. DOI
16. Yin,C., Zheng,L., Chen,L., Tan,Q., Shang,X. and Ma,A.
    Cloning, expression, and characterization of a milk-clotting aspartic protease gene (Po-Asp) from Pleurotus ostreatus
    Appl Biochem Biotechnol172, 2119-2131. PubMed  Europe PubMed DOI
2013
17. Pereira,H., Azevedo,F., Rego,A., Sousa,M.J., Chaves,S.R. and Corte-Real,M.
    The protective role of yeast cathepsin D in acetic acid-induced apoptosis depends on ANT (Aac2p) but not on the voltage-dependent channel (Por1p)
    FEBS Lett587, 200-205. PubMed  Europe PubMed DOI
18. Rajagopalan,A., Schober,M., Emmerstorfer,A., Hammerer,L., Migglautsch,A., Seisser,B., Glueck,S.M., Niehaus,F., Eck,J., Pichler,H., Gruber,K. and Kroutil,W.
    Enzymatic aerobic alkene cleavage catalyzed by a Mn(3+)-dependent proteinase A homologue
    Chembiochem14, 2427-2430. PubMed  Europe PubMed DOI
19. Yang,X., Cong,H., Song,J. and Zhang,J.
    Heterologous expression of an aspartic protease gene from biocontrol fungus Trichoderma asperellum in Pichia pastoris
    World J Microbiol Biotechnol29, 2087-2094. PubMed  Europe PubMed DOI  E
2012
20. Winther,J.R., Webb,H. and Kay,J.
    Saccharopepsin
    [ISSN:978-0-12-407744-7]3, 128-133. DOI
2011
21. Carmona-Gutierrez,D., Bauer,M.A., Ring,J., Knauer,H., Eisenberg,T., Buttner,S., Ruckenstuhl,C., Reisenbichler,A., Magnes,C., Rechberger,G.N., Birner-Gruenberger,R., Jungwirth,H., Frohlich,K.U., Sinner,F., Kroemer,G. and Madeo,F.
    The propeptide of yeast cathepsin D inhibits programmed necrosis
    Cell Death Dis2, e161-e161. PubMed  Europe PubMed DOI  K
2010
22. Guo,Z.P., Zhang,L., Ding,Z.Y., Wang,Z.X. and Shi,G.Y.
    Improving the performance of industrial ethanol-producing yeast by expressing the aspartyl protease on the cell surface
    Yeast27, 1017-1027. PubMed  Europe PubMed DOI
23. Pereira,C., Chaves,S., Alves,S., Salin,B., Camougrand,N., Manon,S., Sousa,M.J. and Corte-Real,M.
    Mitochondrial degradation in acetic acid-induced yeast apoptosis: the role of Pep4 and the ADP/ATP carrier
    Mol Microbiol76, 1398-1410. PubMed  Europe PubMed DOI
24. Spedale,G., Mischerikow,N., Heck,A.J., Timmers,H.T. and Pijnappel,W.W.
    Identification of Pep4p as the protease responsible for formation of the SAGA-related SLIK protein complex
    J Biol Chem285, 22793-22799. PubMed  Europe PubMed DOI
25. ten Have,A., Espino,J.J., Dekkers,E., Van Sluyter,S.C., Brito,N., Kay,J., Gonzalez,C. and van Kan,J.A.
    The Botrytis cinerea aspartic proteinase family
    Fungal Genet Biol47, 53-65. PubMed  Europe PubMed DOI
2009
26. Sabotic,J., Popovic,T. and Brzin,J.
    Aspartic proteases from basidiomycete Clitocybe nebularis
    Croat Chem Acta82, 739-745.
27. Tacco,B.A., Parente,J.A., Barbosa,M.S., Bao,S.N., Goes,T.D., Pereira,M. and Soares,C.M.
    Characterization of a secreted aspartyl protease of the fungal pathogen Paracoccidioides brasiliensis
    Med Mycol47, 845-854. PubMed  Europe PubMed DOI
2007
28. Jin,F.J., Watanabe,T., Juvvadi,P.R., Maruyama,J., Arioka,M. and Kitamoto,K.
    Double disruption of the proteinase genes, tppA and pepE, increases the production level of human lysozyme by Aspergillus oryzae
    Appl Microbiol Biotechnol76, 1059-1068. PubMed  Europe PubMed DOI
29. Parr,C.L., Keates,R.A., Bryksa,B.C., Ogawa,M. and Yada,R.Y.
    The structure and function of Saccharomyces cerevisiae proteinase A
    Yeast24, 467-480. PubMed  Europe PubMed DOI  V
30. Wang,Z.Y., He,X.P. and Zhang,B.R.
    Over-expression of GSH1 gene and disruption of PEP4 gene in self-cloning industrial brewer's yeast
    Int J Food Microbiol119, 192-199. PubMed  Europe PubMed DOI  K
31. Wang,Z.Y., He,G.Q., Ruan,H., Liu,Z.S., Yang,L.F. and Zhang,B.R.
    Construction of proteinase A deficient transformant of industrial brewing yeast
    Eur Food Res Technol225, 831-835. DOI  K
2006
32. Guilloux-Benatier,M., Remize,F., Gal,L., Guzzo,J. and Alexandre,H.
    Effects of yeast proteolytic activity on Oenococcus oeni and malolactic fermentation
    FEMS Microbiol Lett263, 183-188. PubMed  Europe PubMed DOI
33. [YEAR:4-4-2006]Kato,M., Kuzuhara,Y., Maeda,H., Shiraga,S. and Ueda,M.
    Analysis of a processing system for proteases using yeast cell surface engineering: conversion of precursor of proteinase A to active proteinase A
    Appl Microbiol Biotechnol72, 1229-1237. PubMed  Europe PubMed DOI
34. Marques,M., Mojzita,D., Amorim,M.A., Almeida,T., Hohmann,S., Moradas-Ferreira,P. and Costa,V.
    The Pep4p vacuolar proteinase contributes to the turnover of oxidized proteins but PEP4 overexpression is not sufficient to increase chronological lifespan in Saccharomyces cerevisiae
    Microbiology (Reading)152, 3595-3605. PubMed  Europe PubMed DOI
35. Tarcha,E.J., Basrur,V., Hung,C.Y., Gardner,M.J. and Cole,G.T.
    A recombinant aspartyl protease of Coccidioides posadasii induces protection against pulmonary coccidioidomycosis in mice
    Infect Immun74, 516-527. PubMed  Europe PubMed DOI
2005
36. [YEAR:15-1-2005]Bae,J.H., Sohn,J.H., Rhee,S.K. and Choi,E.S.
    Cloning and characterization of the Hansenula polymorpha PEP4 gene encoding proteinase A
    Yeast22, 13-19. PubMed  Europe PubMed DOI
2004
37. Bowman,B.J.
    Neurosporapepsin
    [ISSN:0-12-079610-4]2, 90-91.  V
38. Winther,J.R., Phylip,L. and Kay,J.
    Saccharopepsin
    [ISSN:0-12-079610-4]2, 87-90.  V
2002
39. [YEAR:26-7-2002]Gustchina,A., Li,M., Phylip,L.H., Lees,W.E., Kay,J. and Wlodawer,A.
    An unusual orientation for Tyr75 in the active site of the aspartic proteinase from Saccharomyces cerevisiae
    Biochem Biophys Res Commun295, 1020-1026. PubMed  Europe PubMed DOI  S
40. Komeda,T., Sakai,Y., Kato,N. and Kondo,K.
    Construction of protease-deficient Candida boidinii strains useful for recombinant protein production: cloning and disruption of proteinase A gene (PEP4) and proteinase B gene (PRBI)
    Biosci Biotechnol Biochem66, 628-631. PubMed  Europe PubMed DOI
41. [YEAR:1-5-2002]Kunihiro,S., Kawanishi,Y., Sano,M., Naito,K., Matsuura,Y., Tateno,Y., Gojobori,T., Yamagata,Y., Abe,K. and Machida,M.
    A polymerase chain reaction-based method for cloning novel members of a gene family using a combination of degenerate and inhibitory primers
    Gene289, 177-184. PubMed  Europe PubMed DOI
2001
42. [YEAR:19-1-2001]Phylip,L.H., Lees,W.E., Brownsey,B.G., Bur,D., Dunn,B.M., Winther,J.R., Gustchina,A., Li,M., Copeland,T., Wlodawer,A. and Kay,J.
    The potency and specificity of the interaction between the IA3 inhibitor and its target aspartic proteinase from Saccharomyces cerevisiae
    J Biol Chem276, 2023-2030. PubMed  Europe PubMed DOI
43. Sievi,E., Suntio,T. and Makarow,M.
    Proteolytic function of GPI-anchored plasma membrane protease Yps1p in the yeast vacuole and Golgi
    Traffic2, 896-907. PubMed  Europe PubMed DOI
2000
44. Badasso,M.O., Read,J.A., Dhanaraj,V., Cooper,J.B., Wood,S.P., Blundell,T.L., Dreyer,T. and Winther,J.
    Purification, co-crystallization and preliminary X-ray analysis of the natural aspartic proteinase inhibitor IA3 complexed with saccharopepsin from Saccharomyces cerevisiae
    Acta Crystallogr D Biol Crystallogr56, 915-917. PubMed  Europe PubMed DOI
45. [YEAR:10-11-2000]Cronin,N.B., Badasso,M.O., Tickle,I.J., Dreyer,T., Hoover,D.J., Rosati,R.L., Humblet,C.C., Lunney,E.A. and Cooper,J.B.
    X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity
    J Mol Biol303, 745-760. PubMed  Europe PubMed DOI  S  I
46. [YEAR:11-1-2000]Johnson,S.M., Kerekes,K.M., Zimmermann,C.R., Williams,R.H. and Pappagianis,D.
    Identification and cloning of an aspartyl proteinase from Coccidioides immitis
    Gene241, 213-222. PubMed  Europe PubMed DOI  E
47. Li,M., Phylip,L.H., Lees,W.E., Winther,J.R., Dunn,B.M., Wlodawer,A., Kay,J. and Gustchina,A.
    The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix
    Nat Struct Biol7, 113-117. PubMed  Europe PubMed DOI
48. Reichard,U., Cole,G.T., Ruchel,R. and Monod,M.
    Molecular cloning and targeted deletion of PEP2 which encodes a novel aspartic proteinase from Aspergillus fumigatus
    Int J Med Microbiol290, 85-96. PubMed  Europe PubMed DOI
1998
49. Kondo,H., Shibano,Y., Amachi,T., Cronin,N., Oda,K. and Dunn,B.M.
    Substrate specificities and kinetic properties of proteinase A from the yeast Saccharomyces cerevisiae and the development of a novel substrate
    J Biochem124, 141-147. PubMed  Europe PubMed  P
1997
50. Aguilar,C.F., Cronin,N.B., Badasso,M., Dreyer,T., Newman,M.P., Cooper,J.B., Hoover,D.J., Wood,S.P., Johnson,M.S. and Blundell,T.L.
    The three-dimensional structure at 2.4 A resolution of glycosylated proteinase A from the lysosome-like vacuole of Saccharomyces cerevisiae
    J Mol Biol267, 899-915. PubMed  Europe PubMed DOI  S
51. Van Den Hazel,H., Wolff,A.M., Kielland-Brandt,M.C. and Winther,J.R.
    Mechanism and ion-dependence of in vitro autoactivation of yeast proteinase A: Possible implications for compartmentalized activation in vivo
    Biochem J326, 339-344. PubMed  Europe PubMed
52. van den Hombergh,J.P., Sollewijn Gelpke,M.D., van de Vondervoort,P.J., Buxton,F.P. and Visser,J.
    Disruption of three acid proteases in Aspergillus niger - effects on protease spectrum, intracellular proteolysis, and degradation of target proteins
    Eur J Biochem247, 605-613. PubMed  Europe PubMed  K
1996
53. Gron,S., Biedermann,K. and Emborg,C.
    Production of proteinase A by Saccharomyces cerevisiae in a cell-recycling fermentation system: experiments and computer simulations
    Appl Microbiol Biotechnol44, 724-730. PubMed  Europe PubMed DOI  E
54. Van den Hazel,H.B., Kielland-Brandt,M.C. and Winther,J.R.
    Review: biosynthesis and function of yeast vacuolar proteases
    Yeast12, 1-16. PubMed  Europe PubMed DOI  V
55. Vazquez-Laslop,N., Tenney,K. and Bowman,B.J.
    Characterization of a vacuolar protease in Neurospora crassa and the use of gene RIPing to generate protease-deficient strains
    J Biol Chem271, 21944-21949. PubMed  Europe PubMed DOI
56. Westphal,V., Marcusson,E.G., Winther,J.R., Emr,S.D. and Van den Hazel,H.B.
    Multiple pathways for vacuolar sorting of yeast proteinase A
    J Biol Chem271, 11865-11870. PubMed  Europe PubMed DOI
57. Wolff,A.M., Din,N. and Petersen,J.G.
    Vacuolar and extracellular maturation of Saccharomyces cerevisiae proteinase A
    Yeast12, 823-832. PubMed  Europe PubMed DOI
1995
58. Aguilar,C.F., Dhanaraj,V., Guruprasad,K., Dealwis,C., Badasso,M., Cooper,J.B., Wood,S.P. and Blundell,T.L.
    Comparisons of the three-dimensional structures, specificities and glycosylation of renins, yeast proteinase A and cathepsin D
    Adv Exp Med Biol362, 155-166. PubMed  Europe PubMed
59. Rupp,S. and Wolf,D.H.
    Biogenesis of the yeast vacuole (lysosome). The use of active-site mutants of proteinase yscA to determine the necessity of the enzyme for vacuolar proteinase maturation and proteinase yscb stability
    Eur J Biochem231, 115-125. PubMed  Europe PubMed DOI
60. Van den Hazel,H.B., Kielland-Brandt,M.C. and Winther,J.R.
    Random substitution of large parts of the propeptide of yeast proteinase A
    J Biol Chem270, 8602-8609. PubMed  Europe PubMed DOI  E
1994
61. Jarai,G., van den Hombergh,H. and Buxton,F.P.
    Cloning and characterization of the pepE gene of Aspergillus niger encoding a new aspartic protease and regulation of pepE and pepC
    Gene145, 171-178. PubMed  Europe PubMed DOI
62. Winther,J.R., Raymond,C.K. and Stevens,T.H.
    PEP4
    247-249.
1993
63. [YEAR:20-7-1993]Badasso,M., Wood,S.P., Aguilar,C., Cooper,J.B., Blundell,T.L. and Dreyer,T.
    Crystallization and preliminary crystallographic characterization of aspartic proteinase-A from baker's yeast and its complexes with inhibitors
    J Mol Biol232, 701-703. PubMed  Europe PubMed DOI  S
1992
64. [YEAR:1-7-1992]Van den Hazel,H.B., Kielland-Brandt,M.C. and Winther,J.R.
    Autoactivation of proteinase A initiates activation of yeast vacuolar zymogens
    Eur J Biochem207, 277-283. PubMed  Europe PubMed DOI
1991
65. Rupp,S., Hirsch,H.H. and Wolf,D.H.
    Biogenesis of the yeast vacuole (lysosome). Active site mutation in the vacuolar aspartate proteinase yscA blocks maturation of vacuolar proteinases
    FEBS Lett293, 62-66. PubMed  Europe PubMed DOI
1989
66. Dreyer,T.
    Substrate specificity of proteinase yscA from Saccharomyces cerevisiae
    Carlsberg Res Commun54, 85-97. PubMed  Europe PubMed DOI
1988
67. Klionsky,D.J., Banta,L.M. and Emr,S.D.
    Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information
    Mol Cell Biol8, 2105-2116. PubMed  Europe PubMed
1986
68. Ammerer,G., Hunter,C.P., Rothman,J.H., Saari,G.C., Valls,L.A. and Stevens,T.H.
    PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors
    Mol Cell Biol6, 2490-2499. PubMed  Europe PubMed
69. Dreyer,T., Halkier,B., Svendsen,I. and Ottesen,M.
    Primary structure of the aspartic proteinase A from Saccharomyces cerevisiae
    Carlsberg Res Commun51, 27-41.
70. Rothman,J.H., Hunter,C.P., Valls,L.A. and Stevens,T.H.
    Overproduction-induced mislocalization of a yeast vacuolar protein allows isolation of its structural gene
    Proc Natl Acad Sci U S A83, 3248-3252. PubMed  Europe PubMed
1982
71. [YEAR:10-10-1982]Mechler,B., Muller,M., Muller,H., Meussdoerffer,F. and Wolf,D.H.
    In vivo biosynthesis of the vacuolar proteinases A and B in the yeast Saccharomyces cerevisiae
    J Biol Chem257, 11203-11206. PubMed  Europe PubMed
1980
72. Meussdoerffer,F., Tortora,P. and Holzer,H.
    Purification and properties of proteinase A from yeast
    J Biol Chem255, 12087-12093. PubMed  Europe PubMed
1979
73. Kaehn,K.K., Morr,M. and Kula,M.R.
    Inhibition of the acid proteinase from Neurospora crassa by diazoacetyl-norleucine methyl ester, 1,2-epoxy-3-(4-nitrophenoxy)propane and pepstatin
    Z Physiol Chem360, 791-794. PubMed  Europe PubMed  I
1977
74. Holzer,H., Bunning,P. and Meussdoerffer,F.
    Characteristics and functions of proteinase A and its inhibitors in yeast
    Adv Exp Med Biol95, 271-289. PubMed  Europe PubMed
1975
75. Lenney,J.F.
    Three yeast proteins that specifically inhibit yeast proteases A, B, and C
    J Bacteriol122, 1265-1273. PubMed  Europe PubMed  I
1967
76. Hata,T., Hayashi,R. and Doi,E.
    Purification of yeast proteinases. Part III. Isolation and physicochemical properties of yeast proteinase A and C
    Agric Biol Chem31, 357-367. DOI
77. Hata,T., Hayashi,R. and Doi,E.
    Purification of yeast proteinases. I. Fractionation and some properties of the proteinases
    Agric Biol Chem31, 150-159. DOI
78. Lenney,J.F. and Dalbec,J.M.
    Purification and properties of two proteinases from Saccharomyces cerevisiae
    Arch Biochem Biophys120, 42-48. PubMed  Europe PubMed
1956
79. Lenney,J.F.
    A study of two yeast proteinases
    J Biol Chem221, 919-930. PubMed  Europe PubMed