Structure for peptidase C15.001: pyroglutamyl-peptidase I (prokaryote)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

PDB	Organism	Resolution	Comment
1A2Z_A	Thermococcus litoralis	1.73 Å	mature
One molecule of the tetramer is shown. Catalytic residues are shown in ball-and-stick representation: Glu80 in blue, Cys143 in yellow and His167 in purple.

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TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Bacillus amyloliquefaciens
mature peptidase	2.00 Å	1AUG	1AUG	1AUG	1AUG	1AUG	1AUG	Odagaki et al., 1999
mature peptidase	2.01 Å	3RNZ	3RNZ	3RNZ	3RNZ	3RNZ	3RNZ	Lo et al., 2011
mature peptidase	1.50 Å	3RO0	3RO0	3RO0	3RO0	3RO0	3RO0	Lo et al., 2011
Bacillus anthracis
mature peptidase	2.00 Å	3LAC	3LAC	3LAC	3LAC	3LAC	3LAC
Deinococcus radiodurans
crystal structure of pyrrolidone carboxylate peptidase i from deionococcus radiodurans r1	1.84 Å	5Z40	5Z40	5Z40	5Z40	5Z40	5Z40
crystal structure of pyrrolidone carboxylate peptidase i with disordered loop a from deinococcus radiodurans r1	1.70 Å	5Z47	5Z47	5Z47	5Z47	5Z47	5Z47
crystal structure of pyrrolidone carboxylate peptidase i from deinococcus radiodurans r1 bound to pyroglutamate	1.55 Å	5Z48	5Z48	5Z48	5Z48	5Z48	5Z48
Pyrococcus furiosus
mature peptidase	2.20 Å	1IOF	1IOF	1IOF	1IOF	1IOF	1IOF	Tanaka et al., 2001
Cys142, C188 deletion mutant	2.70 Å	1IOI	1IOI	1IOI	1IOI	1IOI	1IOI	Tanaka et al., 2001
structure of mutant pyrrolidone carboxyl peptidase (e192a) from a hyperthermophile, pyrococcus furiosus	2.00 Å	1X10	1X10	1X10	1X10	1X10	1X10	Kaushik et al., 2006
structure of mutant pyrrolidone carboxyl peptidase (e192d) from a hyperthermophile, pyrococcus furiosus	2.00 Å	1X12	1X12	1X12	1X12	1X12	1X12	Kaushik et al., 2006
structure of mutant pyrrolidone carboxyl peptidase (e192q) from a hyperthermophile, pyrococcus furiosus	2.50 Å	1Z8T	1Z8T	1Z8T	1Z8T	1Z8T	1Z8T	Kaushik et al., 2006
structure of mutant pyrrolidone carboxyl peptidase (e192i) from a hyperthermophile, pyrococcus furiosus	2.00 Å	1Z8W	1Z8W	1Z8W	1Z8W	1Z8W	1Z8W	Kaushik et al., 2006
structure of mutant pyrrolidone carboxyl peptidase (e192v) from a hyperthermophile, pyrococcus furiosus	2.00 Å	1Z8X	1Z8X	1Z8X	1Z8X	1Z8X	1Z8X	Kaushik et al., 2006
fragment 1-204	2.30 Å	2DF5	2DF5	2DF5	2DF5	2DF5	2DF5	Takano et al., 2007
Ala199Pro mutant	2.30 Å	2EO8	2EO8	2EO8	2EO8	2EO8	2EO8
Pyrococcus horikoshii
mature peptidase	1.60 Å	1IU8	1IU8	1IU8	1IU8	1IU8	1IU8	Sokabe et al., 2002
Staphylococcus aureus
mature peptidase	1.25 Å	3GIU	3GIU	3GIU	3GIU	3GIU	3GIU
Thermococcus litoralis
mature peptidase	1.73 Å	1A2Z	1A2Z	1A2Z	1A2Z	1A2Z	1A2Z	Singleton et al., 1999
Thermus thermophilus
mature peptidase	1.90 Å	2EBJ	2EBJ	2EBJ	2EBJ	2EBJ	2EBJ
Xenorhabdus bovienii
crystal structure of a pyrrolidone-carboxylate peptidase 1 (target id nysgrc-012831) from xenorhabdus bovienii ss-2004	2.70 Å	4GXH	4GXH	4GXH	4GXH	4GXH	4GXH
crystal structure of a pyrrolidone-carboxylate peptidase 1 (target id nysgrc-012831) from xenorhabdus bovienii ss-2004 in space group p21	1.55 Å	4HPS	4HPS	4HPS	4HPS	4HPS	4HPS