Literature for peptidase C01.013: cathepsin X

(Topics flags: S Structure, A Assay, P Specificity, K Knockout, E Expression, V Review, M Mutation, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Horvat,S., Zidar,N., Kos,J. and Pislar,A.
   alpha-Enolase and gamma-Enolase Expression in Enriched S- and N-Type SH-SY5Y Cells: Regulatory Role of Cathepsin X
   Mol Neurobiol PubMed  Europe PubMed DOI
2. Meade,R.K., Adefisayo,O.O., Gontijo,M.T.P., Harris,S.J., Pyle,C.J., Wilburn,K.M., Ecker,A.M.V., Hughes,E.J., Garcia,P.D., Ivie,J., McHenry,M.L., Benchek,P.H., Mayanja-Kizza,H., Neff,J.L., Ko,D.C., Stout,J.E., Stein,C.M., Hawn,T.R., Tobin,D.M. and Smith,C.M.
   Cathepsin Z is a conserved susceptibility factor underlying tuberculosis severity
   bioRxiv PubMed  Europe PubMed DOI
2024
3. Deng,T., Lu,X., Jia,X., Du,J., Wang,L., Cao,B., Yang,M., Yin,Y. and Liu,F.
   Cathepsins and cancer risk: a Mendelian randomization study
   Front Endocrinol (Lausanne)15, 1428433-1428433. PubMed  Europe PubMed DOI
4. Xu,B., Mountford,S.J., Thompson,P.E. and Edgington-Mitchell,L.E.
   Expanding the Library of Covalent Cysteine Cathepsin Probes Featuring Sulfoxonium Ylide Electrophiles
   ACS Omega9, 43940-43947. PubMed  Europe PubMed DOI
5. Xu,B., Anderson,B.M., Mountford,S.J., Thompson,P.E., Mintern,J.D. and Edgington-Mitchell,L.E.
   Cathepsin X deficiency alters the processing and localisation of cathepsin L and impairs cleavage of a nuclear cathepsin L substrate
   Biol Chem405, 351-365. PubMed  Europe PubMed DOI
2023
6. Stoka,V., Vasiljeva,O., Nakanishi,H. and Turk,V.
   The Role of Cysteine Protease Cathepsins B, H, C, and X/Z in Neurodegenerative Diseases and Cancer
   Int J Mol Sci24, PubMed  Europe PubMed DOI  V
2020
7. Dolenc,I., Stefe,I., Turk,D., Taler-Vercic,A., Turk,B., Turk,V. and Stoka,V.
   Human cathepsin X/Z is a biologically active homodimer
   Biochim Biophys Acta Proteins Proteom1869, 140567-140567. PubMed  Europe PubMed DOI
8. Fonovic,U.P., Knez,D., Hrast,M., Zidar,N., Proj,M., Gobec,S. and Kos,J.
   Structure-activity relationships of triazole-benzodioxine inhibitors of cathepsin X
   Eur J Med Chem193, 112218-112218. PubMed  Europe PubMed DOI  I
9. Mountford,S.J., Anderson,B.M., Xu,B., Tay,E.S.V., Szabo,M., Hoang,M.L., Diao,J., Aurelio,L., Campden,R.I., Lindstrom,E., Sloan,E.K., Yates,R.M., Bunnett,N.W., Thompson,P.E. and Edgington-Mitchell,L.E.
   Application of a sulfoxonium ylide electrophile to generate cathepsin X-selective activity-based probes
   ACS Chem Biol15, 718-727. PubMed  Europe PubMed DOI  I
10. Pislar,A., Tratnjek,L., Glavan,G., Zidar,N., Zivin,M. and Kos,J.
    Neuroinflammation-Induced Upregulation of Glial Cathepsin X Expression and Activity in vivo
    Front Mol Neurosci13, 575453-575453. PubMed  Europe PubMed DOI
11. Shen,Y., Su,Y., Silva,F.J., Weller,A.H., Sostre-Colon,J., Titchenell,P.M., Steger,D.J., Seale,P. and Soccio,R.E.
    Shared PPARalpha/gamma target genes regulate brown adipocyte thermogenic function
    Cell Rep30, 3079-3091. PubMed  Europe PubMed DOI
2019
12. Cai,X., Gao,C., Song,H., Yang,N., Fu,Q., Tan,F. and Li,C.
    Characterization, expression profiling and functional characterization of cathepsin Z (CTSZ) in turbot (Scophthalmus maximus L.)
    Fish Shellfish Immunol84, 599-608. PubMed  Europe PubMed DOI
13. Choi,K.M., Joo,M.S., Cho,D.H., Han,H.J., Kim,M.S., Cho,M.Y., Jung,S.H., Kim,D.H. and Park,C.I.
    Functional analysis and gene expression profiling of extracellular cathepsin Z in red sea bream, Pagrus major
    Fish Shellfish Immunol93, 208-215. PubMed  Europe PubMed DOI  E
14. Dera,A.A., Ranganath,L., Barraclough,R., Vinjamuri,S., Hamill,S. and Barraclough,D.L.
    Cathepsin Z as a novel potential biomarker for osteoporosis
    Sci Rep9, 9752-9752. PubMed  Europe PubMed DOI
15. Lewis,M.S., Danelishvili,L., Rose,S.J. and Bermudez,L.E.
    MAV_4644 Interaction with the host cathepsin Z protects Mycobacterium avium subsp. hominissuis from rapid macrophage killing
    Microorganisms7, PubMed  Europe PubMed DOI
16. Schwenck,J., Maurer,A., Fehrenbacher,B., Mehling,R., Knopf,P., Mucha,N., Haupt,D., Fuchs,K., Griessinger,C.M., Bukala,D., Holstein,J., Schaller,M., Menendez,I.G., Ghoreschi,K., Quintanilla-Martinez,L., Gutschow,M., Laufer,S., Reinheckel,T., Rocken,M., Kalbacher,H., Pichler,B.J. and Kneilling,M.
    Cysteine-type cathepsins promote the effector phase of acute cutaneous delayed-type hypersensitivity reactions
    Theranostics9, 3903-3917. PubMed  Europe PubMed DOI  K
2018
17. Pislar,A., Tratnjek,L., Glavan,G., Zivin,M. and Kos,J.
    Upregulation of cysteine protease cathepsin X in the 6-hydroxydopamine model of Parkinson's disease
    Front Mol Neurosci11, 412-412. PubMed  Europe PubMed DOI
2017
18. Allan,E.R.O., Campden,R.I., Ewanchuk,B.W., Tailor,P., Balce,D.R., McKenna,N.T., Greene,C.J., Warren,A.L., Reinheckel,T. and Yates,R.M.
    A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis
    J Neuroinflammation14, 103-103. PubMed  Europe PubMed DOI  K
19. Fonovic,U.P., Mitrovic,A., Knez,D., Jakos,T., Pislar,A., Brus,B., Doljak,B., Stojan,J., Zakelj,S., Trontelj,J., Gobec,S. and Kos,J.
    Identification and characterization of the novel reversible and selective cathepsin X inhibitors
    Sci Rep7, 11459-11459. PubMed  Europe PubMed DOI  I
20. Godahewa,G.I., Perera,N.C.N., Lee,S., Kim,M.J. and Lee,J.
    A cysteine protease (cathepsin Z) from disk abalone, Haliotis discus discus: genomic characterization and transcriptional profiling during bacterial infections
    Gene627, 500-507. PubMed  Europe PubMed DOI
21. Orlowski,G.M., Sharma,S., Colbert,J.D., Bogyo,M., Robertson,S.A., Kataoka,H., Chan,F.K. and Rock,K.L.
    Frontline science: multiple cathepsins promote inflammasome-independent, particle-induced cell death during NLRP3-dependent IL-1beta activation
    J Leukoc Biol102, 7-17. PubMed  Europe PubMed DOI
22. Pislar,A., Bozic,B., Zidar,N. and Kos,J.
    Inhibition of cathepsin X reduces the strength of microglial-mediated neuroinflammation
    Neuropharmacology114, 88-100. PubMed  Europe PubMed DOI  I
2016
23. Akkari,L., Gocheva,V., Quick,M.L., Kester,J.C., Spencer,A.K., Garfall,A.L., Bowman,R.L. and Joyce,J.A.
    Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer
    Genes Dev30, 220-232. PubMed  Europe PubMed DOI  K
2015
24. Kos,J., Vizin,T., Fonovic,U.P. and Pislar,A.
    Intracellular signaling by cathepsin X: molecular mechanisms and diagnostic and therapeutic opportunities in cancer
    Semin Cancer Biol31, 76-83. PubMed  Europe PubMed DOI
25. Pecar Fonovic,U. and Kos,J.
    Cathepsin X cleaves profilin 1 C-terminal Tyr139 and influences clathrin-mediated endocytosis
    PLoS ONE10, e0137217-e0137217. PubMed  Europe PubMed DOI
26. Pohl,S. and Hasilik,A.
    Biosynthesis, targeting, and processing of lysosomal proteins: Pulse-chase labeling and immune precipitation
    Methods Cell Biol126, 63-83. PubMed  Europe PubMed DOI
27. Teller,A., Jechorek,D., Hartig,R., Adolf,D., Reissig,K., Roessner,A. and Franke,S.
    Dysregulation of apoptotic signaling pathways by interaction of RPLP0 and cathepsin X/Z in gastric cancer
    Pathol Res Pract211, 62-70. PubMed  Europe PubMed DOI
2014
28. Akkari,L., Gocheva,V., Kester,J.C., Hunter,K.E., Quick,M.L., Sevenich,L., Wang,H.W., Peters,C., Tang,L.H., Klimstra,D.S., Reinheckel,T. and Joyce,J.A.
    Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix
    Genes Dev28, 2134-2150. PubMed  Europe PubMed DOI
2013
29. Bak,H.J., Kim,M.S., Kim,N.Y., Go,H.J., Han,J.W., In Jo,H., Ahn,S.J., Park,N.G., Chung,J.K. and Lee,H.H.
    Molecular cloning, expression, and enzymatic analysis of cathepsin X from starfish (Asterina pectinifera)
    Appl Biochem Biotechnol169, 847-861. PubMed  Europe PubMed DOI
30. Buhler,A., Berger,S., Bengsch,F., Martin,G., Han,H., Vierkotten,S., Pielen,A., Boehringer,D., Schlunck,G., Fauser,S., Agostini,H.T., Reinheckel,T. and Stahl,A.
    Cathepsin proteases promote angiogenic sprouting and laser-induced choroidal neovascularisation in mice
    Exp Eye Res115, 73-78. PubMed  Europe PubMed DOI  K
31. Hafner,A., Glavan,G., Obermajer,N., Zivin,M., Schliebs,R. and Kos,J.
    Neuroprotective role of gamma-enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X
    Aging Cell12, 604-614. PubMed  Europe PubMed DOI
32. Pecar Fonovic,U., Jevnikar,Z., Rojnik,M., Doljak,B., Fonovic,M., Jamnik,P. and Kos,J.
    Profilin 1 as a target for cathepsin X activity in tumor cells
    PLoS ONE8, e53918-e53918. PubMed  Europe PubMed DOI  I
33. Serrano-Luna,J., Pina-Vazquez,C., Reyes-Lopez,M., Ortiz-Estrada,G. and de la Garza,M.
    Proteases from Entamoeba spp. and pathogenic free-living amoebae as virulence factors
    J Trop Med2013, 890603-890603. PubMed  Europe PubMed DOI  V
34. Skvarc,M., Stubljar,D., Kopitar,A.N., Jeverica,S., Tepes,B., Kos,J. and Ihan,A.
    Inhibition of cathepsin X enzyme influences the immune response of THP-1 cells and dendritic cells infected with Helicobacter pylori
    Radiol Oncol47, 258-265. PubMed  Europe PubMed DOI  I
2012
35. Kraus,S., Fruth,M., Bunsen,T. and Nagler,D.K.
    IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells
    Biol Chem393, 1457-1462. PubMed  Europe PubMed DOI  K
36. Lines,K.E., Chelala,C., Dmitrovic,B., Wijesuriya,N., Kocher,H.M., Marshall,J.F. and Crnogorac-Jurcevic,T.
    S100P-binding protein, S100PBP, mediates adhesion through regulation of cathepsin Z in pancreatic cancer cells
    Am J Pathol180, 1485-1494. PubMed  Europe PubMed DOI
37. Nagler,D.K., Menard,R. and Sulea,T.
    Cathepsin X
    [ISSN:978-0-12-407743-0]3, 1839-1844. DOI
2011
38. Adams,L.A., Moller,M., Nebel,A., Schreiber,S., vanderMerwe,L., vanHelden,P.D. and Hoal,E.G.
    Polymorphisms in MC3R promoter and CTSZ 3'UTR are associated with tuberculosis susceptibility
    Eur J Hum Genet19, 676-681. PubMed  Europe PubMed DOI
39. Baker,A.R., Zalwango,S., Malone,L.L., Igo,R.P., Jr., Qiu,F., Nsereko,M., Adams,M.D., Supelak,P., Mayanja-Kizza,H., Boom,W.H. and Stein,C.M.
    Genetic susceptibility to tuberculosis associated with cathepsin Z haplotype in a Ugandan household contact study
    Hum Immunol72, 426-430. PubMed  Europe PubMed DOI  M
40. Jevnikar,Z., Obermajer,N. and Kos,J.
    LFA-1 fine-tuning by cathepsin X
    IUBMB Life63, 686-693. PubMed  Europe PubMed DOI
41. Jevnikar,Z., Obermajer,N., Doljak,B., Turk,S., Gobec,S., Svajger,U., Hailfinger,S., Thome,M. and Kos,J.
    Cathepsin X cleavage of the beta2 integrin regulates talin-binding and LFA-1 affinity in T cells
    J Leukoc Biol90, 99-109. PubMed  Europe PubMed DOI
42. Kraus,S., Bunsen,T., Schuster,S., Cichon,M.A., Tacke,M., Reinheckel,T., Sommerhoff,C.P., Jochum,M. and Nagler,D.K.
    Cellular senescence induced by cathepsin X downregulation
    Eur J Cell Biol90, 678-686. PubMed  Europe PubMed DOI  K
43. Paulick,M.G. and Bogyo,M.
    Development of activity-based probes for cathepsin X
    ACS Chem Biol6, 563-572. PubMed  Europe PubMed DOI
44. Ratovitski,T., Chighladze,E., Waldron,E., Hirschhorn,R.R. and Ross,C.A.
    Cysteine proteases bleomycin hydrolase and cathepsin Z mediate N-terminal proteolysis and toxicity of mutant huntingtin
    J Biol Chem286, 12578-12589. PubMed  Europe PubMed DOI
45. Wang,J., Chen,L., Li,Y. and Guan,X.Y.
    Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma
    PLoS ONE6, e24967-e24967. PubMed  Europe PubMed DOI
2010
46. Bernhardt,A., Kuester,D., Roessner,A., Reinheckel,T. and Krueger,S.
    Cathepsin X-deficient gastric epithelial cells in co-culture with macrophages: characterization of cytokine response and migration capability after Helicobacter pylori infection
    J Biol Chem285, 33691-33700. PubMed  Europe PubMed DOI  K
47. Nagler,D.K., Kraus,S., Feierler,J., Mentele,R., Lottspeich,F., Jochum,M. and Faussner,A.
    A cysteine-type carboxypeptidase, cathepsin X, generates peptide receptor agonists
    Int Immunopharmacol10, 134-139. PubMed  Europe PubMed DOI
48. Sevenich,L., Schurigt,U., Sachse,K., Gajda,M., Werner,F., Muller,S., Vasiljeva,O., Schwinde,A., Klemm,N., Deussing,J., Peters,C. and Reinheckel,T.
    Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice
    Proc Natl Acad Sci U S A107, 2497-2502. PubMed  Europe PubMed DOI  K
49. Staudt,N.D., Aicher,W.K., Kalbacher,H., Stevanovic,S., Carmona,A.K., Bogyo,M. and Klein,G.
    Cathepsin X is secreted by human osteoblasts, digests CXCL-12 and impairs adhesion of hematopoietic stem and progenitor cells to osteoblasts
    Haematologica95, 1452-1460. PubMed  Europe PubMed DOI
2009
50. Fonovic,U.P. and Kos,J.
    Efficient removal of cathepsin L from active cathepsin X using immunoprecipitation technique
    Acta Chim Slov56, 985-988.
51. Jevnikar,Z., Obermajer,N., Pecar-Fonovic,U., Karaoglanovic-Carmona,A. and Kos,J.
    Cathepsin X cleaves the beta2 cytoplasmic tail of LFA-1 inducing the intermediate affinity form of LFA-1 and alpha-actinin-1 binding
    Eur J Immunol39, 3217-3227. PubMed  Europe PubMed DOI
52. Kos,J., Jevnikar,Z. and Obermajer,N.
    The role of cathepsin X in cell signaling
    Cell Adh Migr3, 164-166. PubMed  Europe PubMed DOI
53. Obermajer,N., Jevnikar,Z., Doljak,B., Sadaghiani,A.M., Bogyo,M. and Kos,J.
    Cathepsin X-mediated beta2 integrin activation results in nanotube outgrowth
    Cell Mol Life Sci66, 1126-1134. PubMed  Europe PubMed DOI
54. Obermajer,N., Doljak,B., Jamnik,P., Fonovic,U.P. and Kos,J.
    Cathepsin X cleaves the C-terminal dipeptide of alpha- and gamma-enolase and impairs survival and neuritogenesis of neuronal cells
    Int J Biochem Cell Biol41, 1685-1696. PubMed  Europe PubMed DOI  P
55. Obermajer,N., Magister,S., Kopitar,A.N., Tepes,B., Ihan,A. and Kos,J.
    Cathepsin X prevents an effective immune response against Helicobacter pylori infection
    Eur J Cell Biol88, 461-471. PubMed  Europe PubMed DOI
2008
56. Ahn,S.J., Kim,N.Y., Jeon,S.J., Sung,J.H., Je,J.E., Seo,J.S., Kim,M.S., Kim,J.K., Chung,J.K. and Lee,H.H.
    Molecular cloning, tissue distribution and enzymatic characterization of cathepsin X from olive flounder (Paralichthys olivaceus)
    Comp Biochem Physiol B Biochem Mol Biol151, 203-212. PubMed  Europe PubMed DOI
57. Cooke,G.S., Campbell,S.J., Bennett,S., Lienhardt,C., McAdam,K.P., Sirugo,G., Sow,O., Gustafson,P., Mwangulu,F., Van Helden,P., Fine,P., Hoal,E.G. and Hill,A.V.
    Mapping of a novel susceptibility locus suggests a role for MC3R and CTSZ in human tuberculosis
    Am J Respir Crit Care Med178, 203-207. PubMed  Europe PubMed DOI
58. Jevnikar,Z., Obermajer,N., Bogyo,M. and Kos,J.
    The role of cathepsin X in the migration and invasiveness of T lymphocytes
    J Cell Sci121, 2652-2661. PubMed  Europe PubMed DOI
59. Kao,C.M. and Huang,F.L.
    Cloning and expression of carp cathepsin Z: possible involvement in yolk metabolism
    Comp Biochem Physiol B Biochem Mol Biol149, 541-551. PubMed  Europe PubMed DOI
60. Obermajer,N., Svajger,U., Bogyo,M., Jeras,M. and Kos,J.
    Maturation of dendritic cells depends on proteolytic cleavage by cathepsin X
    J Leukoc Biol84, 1306-1315. PubMed  Europe PubMed DOI
61. Obermajer,N., Repnik,U., Jevnikar,Z., Turk,B., Kreft,M. and Kos,J.
    Cysteine protease cathepsin X modulates immune response via activation of beta2 integrins
    Immunology124, 76-88. PubMed  Europe PubMed DOI
2006
62. Lechner,A.M., Assfalg-Machleidt,I., Zahler,S., Stoeckelhuber,M., Machleidt,W., Jochum,M. and Nagler,D.K.
    RGD-dependent binding of procathepsin X to integrin alpha vbeta 3 mediates cell-adhesive properties
    J Biol Chem281, 39588-39597. PubMed  Europe PubMed DOI
63. [YEAR:9-12-2006]Nagler,D.K., Lechner,A.M., Oettl,A., Kozaczynska,K., Scheuber,H.P., Gippner-Steppert,C., Bogner,V., Biberthaler,P. and Jochum,M.
    An enzyme-linked immunosorbent assay for human cathepsin X, a potential new inflammatory marker
    J Immunol Methods308, 241-250. PubMed  Europe PubMed DOI  A
64. [YEAR:11-5-2006]Obermajer,N., Premzl,A., Zavasnik Bergant,T., Turk,B. and Kos,J.
    Carboxypeptidase cathepsin X mediates beta2-integrin-dependent adhesion of differentiated U-937 cells
    Exp Cell Res312, 2515-2527. PubMed  Europe PubMed DOI
2005
65. [YEAR:5-1-2005]Appenzeller-Herzog,C., Nyfeler,B., Burkhard,P., Santamaria,I., Lopez-Otin,C. and Hauri,H.P.
    Carbohydrate- and conformation-dependent cargo capture for ER-Exit
    Mol Biol Cell16, 1258-1267. PubMed  Europe PubMed DOI
66. [YEAR:8-4-2005]Devanathan,G., Turnbull,J.L., Ziomek,E., Purisima,E.O., Menard,R. and Sulea,T.
    Carboxy-monopeptidase substrate specificity of human cathepsin X
    Biochem Biophys Res Commun329, 445-452. PubMed  Europe PubMed DOI  P
67. [YEAR:15-7-2005]Krueger,S., Kalinski,T., Hundertmark,T., Wex,T., Kuster,D., Peitz,U., Ebert,M., Nagler,D.K., Kellner,U., Malfertheiner,P., Naumann,M., Rocken,C. and Roessner,A.
    Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer
    J Pathol207, 32-42. PubMed  Europe PubMed DOI
68. [YEAR:15-4-2005]Nascimento,F.D., Rizzi,C.C., Nantes,I.L., Stefe,I., Turk,B., Carmona,A.K., Nader,H.B., Juliano,L. and Tersariol,I.L.
    Cathepsin X binds to cell surface heparan sulfate proteoglycans
    Arch Biochem Biophys436, 323-332. PubMed  Europe PubMed DOI
69. Puzer,L., Cotrin,S.S., Cezari,M.H., Hirata,I.Y., Juliano,M.A., Stefe,I., Turk,D., Turk,B., Juliano,L. and Carmona,A.K.
    Recombinant human cathepsin X is a carboxymonopeptidase only: a comparison with cathepsins B and L
    Biol Chem386, 1191-1195. PubMed  Europe PubMed DOI
2004
70. Lustigman,S., Zhang,J., Liu,J., Oksov,Y. and Hashmi,S.
    RNA interference targeting cathepsin L and Z-like cysteine proteases of Onchocerca volvulus confirmed their essential function during L3 molting
    Mol Biochem Parasitol138, 165-170. PubMed  Europe PubMed DOI
71. Menard,R. and Sulea,T.
    Cathepsin X
    [ISSN:0-12-079610-4]2, 1113-1116.  V
72. [YEAR:1-7-2004]Nagler,D.K., Kruger,S., Kellner,A., Ziomek,E., Menard,R., Buhtz,P., Krams,M., Roessner,A. and Kellner,U.
    Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia
    Prostate60, 109-119. PubMed  Europe PubMed DOI
2003
73. Kelley,G.O., Adkison,M.A., Leutenegger,C.M. and Hedrick,R.P.
    Myxobolus cerebralis: identification of a cathepsin Z-like protease gene (MyxCP-1) expressed during parasite development in rainbow trout, Oncorhynchus mykiss
    Exp Parasitol105, 201-210. PubMed  Europe PubMed DOI
2002
74. Nakazono,E., Kamata,Y. and Yamafuji,K.
    Determination of the mRNA sequence of cathepsin Y, a cysteine endopeptidase from rat spleen, and confirmation of its ubiquitous expression
    Biol Chem383, 1971-1975. PubMed  Europe PubMed DOI
2001
75. Menard,R., Therrien,C., Lachance,P., Sulea,T., Qo,H., Alvarez-Hernandez,A.D. and Roush,W.R.
    Cathepsins X and B display distinct activity profiles that can be exploited for inhibitor design
    Biol Chem382, 839-845. PubMed  Europe PubMed DOI  I
76. [YEAR:6-3-2001]Therrien,C., Lachance,P., Sulea,T., Purisima,E.O., Qi,H., Ziomek,E., Alvarez-Hernandez,A., Roush,W.R. and Menard,R.
    Cathepsins X and B can be differentiated through their respective mono- and dipeptidyl carboxypeptidase activities
    Biochemistry40, 2702-2711. PubMed  Europe PubMed DOI  I
2000
77. [YEAR:15-3-2000]Guncar,G., Klemencic,I., Turk,B., Turk,V., Karaoglanovic-Carmona,A., Juliano,L. and Turk,D.
    Crystal structure of cathepsin X: a flip-flop of the ring of His23 allows carboxy-monopeptidase and carboxy-dipeptidase activity of the protease
    Structure8, 305-313. PubMed  Europe PubMed DOI  S
78. Klemencic,I., Carmona,A.K., Cezari,M.H.S., Juliano,M.A., Juliano,L., Guncar,G., Turk,D., Krizaj,I., Turk,V. and Turk,B.
    Biochemical characterization of human cathepsin X revealed that the enzyme is an exopeptidase, acting as carboxymonopeptidase or carboxydipeptidase
    Eur J Biochem267, 5404-5412. PubMed  Europe PubMed DOI  I
79. [YEAR:28-1-2000]Sivaraman,J., Nagler,D.K., Zhang,R., Menard,R. and Cygler,M.
    Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine
    J Mol Biol295, 939-951. PubMed  Europe PubMed DOI  S
1999
80. Appenzeller,C., Andersson,H., Kappeler,F. and Hauri,H.P.
    The lectin ERGIC-53 is a cargo transport receptor for glycoproteins
    Nat Cell Biol1, 330-334. PubMed  Europe PubMed DOI
81. [YEAR:28-9-1999]Nagler,D.K., Zhang,R., Tam,W., Sulea,T., Purisima,E.O. and Menard,R.
    Human cathepsin X: A cysteine protease with unique carboxypeptidase activity
    Biochemistry38, 12648-12654. PubMed  Europe PubMed DOI
1998
82. Barrett,A.J.
    Cysteine-type carboxypeptidase, carboxypeptidase LB
    1, 789-791.  V
83. [YEAR:28-8-1998]Nagler,D.K. and Menard,R.
    Human cathepsin X: A novel cysteine protease of the papain family with a very short proregion and unique insertions
    FEBS Lett434, 135-139. PubMed  Europe PubMed DOI
84. [YEAR:3-7-1998]Santamaria,I., Velasco,G., Pendas,A.M., Fueyo,A. and Lopez-Otin,C.
    Cathepsin Z, a novel human cysteine proteinase with a short propeptide domain and a unique chromosomal location
    J Biol Chem273, 16816-16823. PubMed  Europe PubMed DOI
1996
85. Lustigman,S., McKerrow,J.H., Shah,K., Lui,J., Huima,T., Hough,M. and Brotman,B.
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