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Literature for peptidase C01.013: cathepsin X

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, P Specificity, K Knockout, E Expression, V Review, M Mutation, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Horvat,S., Pecar Fonovic,U., Zidar,N., Doljak,B., Kos,J. and Pislar,A.
    Neuronal Subtype-Specific Expression of gamma-Enolase: Its Role in Neuronal Differentiation
    Neuromolecular Med (2026) 28, 4-4. PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2025
  2. Horvat,S., Zidar,N., Kos,J. and Pislar,A.
    alpha-Enolase and gamma-Enolase Expression in Enriched S- and N-Type SH-SY5Y Cells: Regulatory Role of Cathepsin X
    Mol Neurobiol (2025) PubMed  Europe PubMed DOI
  3. Meade,R.K., Adefisayo,O.O., Gontijo,M.T.P., Harris,S.J., Pyle,C.J., Wilburn,K.M., Ecker,A.M.V., Hughes,E.J., Garcia,P.D., Ivie,J., McHenry,M.L., Benchek,P.H., Mayanja-Kizza,H., Neff,J.L., Ko,D.C., Stout,J.E., Stein,C.M., Hawn,T.R., Tobin,D.M. and Smith,C.M.
    Cathepsin Z is a conserved susceptibility factor underlying tuberculosis severity
    bioRxiv (2025) PubMed  Europe PubMed DOI  PMC  EPMC
  4. Mizrachi,A., Sadeh,M., Ben-Dor,S., Dym,O., Ku,C., Feldmesser,E., Zarfin,A., Brunson,J.K., Allen,A.E., Jinkerson,R.E., Schatz,D. and Vardi,A.
    Cathepsin X is a conserved cell death protein involved in algal response to environmental stress
    Curr Biol (2025) PubMed  Europe PubMed DOI
  5. Tao,J., Chen,Y., Bian,X., Cai,T., Song,C., Liang,C., Hao,Z., Meng,J., Ge,Q. and Zhou,J.
    Prognostic and immunological implications of cathepsin Z overexpression in prostate cancer
    Front Immunol (2025) 16, 1618487-1618487. PubMed  Europe PubMed DOI  PMC  EPMC  K
    6. 2024
  6. Deng,T., Lu,X., Jia,X., Du,J., Wang,L., Cao,B., Yang,M., Yin,Y. and Liu,F.
    Cathepsins and cancer risk: a Mendelian randomization study
    Front Endocrinol (Lausanne) (2024) 15, 1428433-1428433. PubMed  Europe PubMed DOI  PMC  EPMC
  7. Gallwitz,L., Bleibaum,F., Voss,M., Schweizer,M., Spengler,K., Winter,D., Zophel,F., Muller,S., Lichtenthaler,S., Damme,M. and Saftig,P.
    Cellular depletion of major cathepsin proteases reveals their concerted activities for lysosomal proteolysis
    Cell Mol Life Sci (2024) 81, 227-227. PubMed  Europe PubMed DOI  PMC  EPMC
  8. Xu,B., Anderson,B.M., Mountford,S.J., Thompson,P.E., Mintern,J.D. and Edgington-Mitchell,L.E.
    Cathepsin X deficiency alters the processing and localisation of cathepsin L and impairs cleavage of a nuclear cathepsin L substrate
    Biol Chem (2024) 405, 351-365. PubMed  Europe PubMed DOI
  9. Xu,B., Mountford,S.J., Thompson,P.E. and Edgington-Mitchell,L.E.
    Expanding the Library of Covalent Cysteine Cathepsin Probes Featuring Sulfoxonium Ylide Electrophiles
    ACS Omega (2024) 9, 43940-43947. PubMed  Europe PubMed DOI  PMC  EPMC
    10. 2023
  10. Malovitski,K., Sarig,O., Feller,Y., Bergson,S., Assaf,S., Mohamad,J., Pavlovsky,M., Giladi,M. and Sprecher,E.
    Defective cathepsin Z affects EGFR expression and causes autosomal dominant palmoplantar keratoderma
    Br J Dermatol (2023) 189, 302-311. PubMed  Europe PubMed DOI
  11. Stoka,V., Vasiljeva,O., Nakanishi,H. and Turk,V.
    The Role of Cysteine Protease Cathepsins B, H, C, and X/Z in Neurodegenerative Diseases and Cancer
    Int J Mol Sci (2023) 24 PubMed  Europe PubMed DOI  PMC  EPMC  V
    12. 2020
  12. Dolenc,I., Stefe,I., Turk,D., Taler-Vercic,A., Turk,B., Turk,V. and Stoka,V.
    Human cathepsin X/Z is a biologically active homodimer
    Biochim Biophys Acta Proteins Proteom (2020) 1869, 140567-140567. PubMed  Europe PubMed DOI
  13. Fonovic,U.P., Knez,D., Hrast,M., Zidar,N., Proj,M., Gobec,S. and Kos,J.
    Structure-activity relationships of triazole-benzodioxine inhibitors of cathepsin X
    Eur J Med Chem (2020) 193, 112218-112218. PubMed  Europe PubMed DOI  I
  14. Mountford,S.J., Anderson,B.M., Xu,B., Tay,E.S.V., Szabo,M., Hoang,M.L., Diao,J., Aurelio,L., Campden,R.I., Lindstrom,E., Sloan,E.K., Yates,R.M., Bunnett,N.W., Thompson,P.E. and Edgington-Mitchell,L.E.
    Application of a sulfoxonium ylide electrophile to generate cathepsin X-selective activity-based probes
    ACS Chem Biol (2020) 15, 718-727. PubMed  Europe PubMed DOI  I
  15. Pislar,A., Tratnjek,L., Glavan,G., Zidar,N., Zivin,M. and Kos,J.
    Neuroinflammation-Induced Upregulation of Glial Cathepsin X Expression and Activity in vivo
    Front Mol Neurosci (2020) 13, 575453-575453. PubMed  Europe PubMed DOI  PMC  EPMC
  16. Shen,Y., Su,Y., Silva,F.J., Weller,A.H., Sostre-Colon,J., Titchenell,P.M., Steger,D.J., Seale,P. and Soccio,R.E.
    Shared PPARalpha/gamma target genes regulate brown adipocyte thermogenic function
    Cell Rep (2020) 30, 3079-3091. PubMed  Europe PubMed DOI
    17. 2019
  17. Cai,X., Gao,C., Song,H., Yang,N., Fu,Q., Tan,F. and Li,C.
    Characterization, expression profiling and functional characterization of cathepsin Z (CTSZ) in turbot (Scophthalmus maximus L.)
    Fish Shellfish Immunol (2019) 84, 599-608. PubMed  Europe PubMed DOI
  18. Choi,K.M., Joo,M.S., Cho,D.H., Han,H.J., Kim,M.S., Cho,M.Y., Jung,S.H., Kim,D.H. and Park,C.I.
    Functional analysis and gene expression profiling of extracellular cathepsin Z in red sea bream, Pagrus major
    Fish Shellfish Immunol (2019) 93, 208-215. PubMed  Europe PubMed DOI  E
  19. Dera,A.A., Ranganath,L., Barraclough,R., Vinjamuri,S., Hamill,S. and Barraclough,D.L.
    Cathepsin Z as a novel potential biomarker for osteoporosis
    Sci Rep (2019) 9, 9752-9752. PubMed  Europe PubMed DOI  PMC  EPMC
  20. Lewis,M.S., Danelishvili,L., Rose,S.J. and Bermudez,L.E.
    MAV_4644 Interaction with the host cathepsin Z protects Mycobacterium avium subsp. hominissuis from rapid macrophage killing
    Microorganisms (2019) 7 PubMed  Europe PubMed DOI
  21. Schwenck,J., Maurer,A., Fehrenbacher,B., Mehling,R., Knopf,P., Mucha,N., Haupt,D., Fuchs,K., Griessinger,C.M., Bukala,D., Holstein,J., Schaller,M., Menendez,I.G., Ghoreschi,K., Quintanilla-Martinez,L., Gutschow,M., Laufer,S., Reinheckel,T., Rocken,M., Kalbacher,H., Pichler,B.J. and Kneilling,M.
    Cysteine-type cathepsins promote the effector phase of acute cutaneous delayed-type hypersensitivity reactions
    Theranostics (2019) 9, 3903-3917. PubMed  Europe PubMed DOI  PMC  EPMC  K
    22. 2018
  22. Pislar,A., Tratnjek,L., Glavan,G., Zivin,M. and Kos,J.
    Upregulation of cysteine protease cathepsin X in the 6-hydroxydopamine model of Parkinson's disease
    Front Mol Neurosci (2018) 11, 412-412. PubMed  Europe PubMed DOI  PMC  EPMC
    23. 2017
  23. Allan,E.R.O., Campden,R.I., Ewanchuk,B.W., Tailor,P., Balce,D.R., McKenna,N.T., Greene,C.J., Warren,A.L., Reinheckel,T. and Yates,R.M.
    A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis
    J Neuroinflammation (2017) 14, 103-103. PubMed  Europe PubMed DOI  PMC  EPMC  K
  24. Fonovic,U.P., Mitrovic,A., Knez,D., Jakos,T., Pislar,A., Brus,B., Doljak,B., Stojan,J., Zakelj,S., Trontelj,J., Gobec,S. and Kos,J.
    Identification and characterization of the novel reversible and selective cathepsin X inhibitors
    Sci Rep (2017) 7, 11459-11459. PubMed  Europe PubMed DOI  PMC  EPMC  I
  25. Godahewa,G.I., Perera,N.C.N., Lee,S., Kim,M.J. and Lee,J.
    A cysteine protease (cathepsin Z) from disk abalone, Haliotis discus discus: genomic characterization and transcriptional profiling during bacterial infections
    Gene (2017) 627, 500-507. PubMed  Europe PubMed DOI
  26. Orlowski,G.M., Sharma,S., Colbert,J.D., Bogyo,M., Robertson,S.A., Kataoka,H., Chan,F.K. and Rock,K.L.
    Frontline science: multiple cathepsins promote inflammasome-independent, particle-induced cell death during NLRP3-dependent IL-1beta activation
    J Leukoc Biol (2017) 102, 7-17. PubMed  Europe PubMed DOI
  27. Pislar,A., Bozic,B., Zidar,N. and Kos,J.
    Inhibition of cathepsin X reduces the strength of microglial-mediated neuroinflammation
    Neuropharmacology (2017) 114, 88-100. PubMed  Europe PubMed DOI  I
    28. 2016
  28. Akkari,L., Gocheva,V., Quick,M.L., Kester,J.C., Spencer,A.K., Garfall,A.L., Bowman,R.L. and Joyce,J.A.
    Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer
    Genes Dev (2016) 30, 220-232. PubMed  Europe PubMed DOI  PMC  EPMC  K
    29. 2015
  29. Kos,J., Vizin,T., Fonovic,U.P. and Pislar,A.
    Intracellular signaling by cathepsin X: molecular mechanisms and diagnostic and therapeutic opportunities in cancer
    Semin Cancer Biol (2015) 31, 76-83. PubMed  Europe PubMed DOI
  30. Pecar Fonovic,U. and Kos,J.
    Cathepsin X cleaves profilin 1 C-terminal Tyr139 and influences clathrin-mediated endocytosis
    PLoS ONE (2015) 10, e0137217-e0137217. PubMed  Europe PubMed DOI
  31. Pohl,S. and Hasilik,A.
    Biosynthesis, targeting, and processing of lysosomal proteins: Pulse-chase labeling and immune precipitation
    Methods Cell Biol (2015) 126, 63-83. PubMed  Europe PubMed DOI
  32. Teller,A., Jechorek,D., Hartig,R., Adolf,D., Reissig,K., Roessner,A. and Franke,S.
    Dysregulation of apoptotic signaling pathways by interaction of RPLP0 and cathepsin X/Z in gastric cancer
    Pathol Res Pract (2015) 211, 62-70. PubMed  Europe PubMed DOI
    33. 2014
  33. Akkari,L., Gocheva,V., Kester,J.C., Hunter,K.E., Quick,M.L., Sevenich,L., Wang,H.W., Peters,C., Tang,L.H., Klimstra,D.S., Reinheckel,T. and Joyce,J.A.
    Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix
    Genes Dev (2014) 28, 2134-2150. PubMed  Europe PubMed DOI  PMC  EPMC
    34. 2013
  34. Bak,H.J., Kim,M.S., Kim,N.Y., Go,H.J., Han,J.W., In Jo,H., Ahn,S.J., Park,N.G., Chung,J.K. and Lee,H.H.
    Molecular cloning, expression, and enzymatic analysis of cathepsin X from starfish (Asterina pectinifera)
    Appl Biochem Biotechnol (2013) 169, 847-861. PubMed  Europe PubMed DOI
  35. Buhler,A., Berger,S., Bengsch,F., Martin,G., Han,H., Vierkotten,S., Pielen,A., Boehringer,D., Schlunck,G., Fauser,S., Agostini,H.T., Reinheckel,T. and Stahl,A.
    Cathepsin proteases promote angiogenic sprouting and laser-induced choroidal neovascularisation in mice
    Exp Eye Res (2013) 115, 73-78. PubMed  Europe PubMed DOI  K
  36. Hafner,A., Glavan,G., Obermajer,N., Zivin,M., Schliebs,R. and Kos,J.
    Neuroprotective role of gamma-enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X
    Aging Cell (2013) 12, 604-614. PubMed  Europe PubMed DOI
  37. Pecar Fonovic,U., Jevnikar,Z., Rojnik,M., Doljak,B., Fonovic,M., Jamnik,P. and Kos,J.
    Profilin 1 as a target for cathepsin X activity in tumor cells
    PLoS ONE (2013) 8, e53918-e53918. PubMed  Europe PubMed DOI  PMC  EPMC  I
  38. Serrano-Luna,J., Pina-Vazquez,C., Reyes-Lopez,M., Ortiz-Estrada,G. and de la Garza,M.
    Proteases from Entamoeba spp. and pathogenic free-living amoebae as virulence factors
    J Trop Med (2013) 2013, 890603-890603. PubMed  Europe PubMed DOI  PMC  EPMC  V
  39. Skvarc,M., Stubljar,D., Kopitar,A.N., Jeverica,S., Tepes,B., Kos,J. and Ihan,A.
    Inhibition of cathepsin X enzyme influences the immune response of THP-1 cells and dendritic cells infected with Helicobacter pylori
    Radiol Oncol (2013) 47, 258-265. PubMed  Europe PubMed DOI  PMC  EPMC  I
    40. 2012
  40. Kraus,S., Fruth,M., Bunsen,T. and Nagler,D.K.
    IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells
    Biol Chem (2012) 393, 1457-1462. PubMed  Europe PubMed DOI  K
  41. Lines,K.E., Chelala,C., Dmitrovic,B., Wijesuriya,N., Kocher,H.M., Marshall,J.F. and Crnogorac-Jurcevic,T.
    S100P-binding protein, S100PBP, mediates adhesion through regulation of cathepsin Z in pancreatic cancer cells
    Am J Pathol (2012) 180, 1485-1494. PubMed  Europe PubMed DOI
  42. Nagler,D.K., Menard,R. and Sulea,T.
    Cathepsin X
    [ISSN:978-0-12-407743-0] (2012) 3, 1839-1844. DOI
    43. 2011
  43. Adams,L.A., Moller,M., Nebel,A., Schreiber,S., vanderMerwe,L., vanHelden,P.D. and Hoal,E.G.
    Polymorphisms in MC3R promoter and CTSZ 3'UTR are associated with tuberculosis susceptibility
    Eur J Hum Genet (2011) 19, 676-681. PubMed  Europe PubMed DOI
  44. Baker,A.R., Zalwango,S., Malone,L.L., Igo,R.P., Jr., Qiu,F., Nsereko,M., Adams,M.D., Supelak,P., Mayanja-Kizza,H., Boom,W.H. and Stein,C.M.
    Genetic susceptibility to tuberculosis associated with cathepsin Z haplotype in a Ugandan household contact study
    Hum Immunol (2011) 72, 426-430. PubMed  Europe PubMed DOI  M
  45. Jevnikar,Z., Obermajer,N., Doljak,B., Turk,S., Gobec,S., Svajger,U., Hailfinger,S., Thome,M. and Kos,J.
    Cathepsin X cleavage of the beta2 integrin regulates talin-binding and LFA-1 affinity in T cells
    J Leukoc Biol (2011) 90, 99-109. PubMed  Europe PubMed DOI
  46. Jevnikar,Z., Obermajer,N. and Kos,J.
    LFA-1 fine-tuning by cathepsin X
    IUBMB Life (2011) 63, 686-693. PubMed  Europe PubMed DOI
  47. Kraus,S., Bunsen,T., Schuster,S., Cichon,M.A., Tacke,M., Reinheckel,T., Sommerhoff,C.P., Jochum,M. and Nagler,D.K.
    Cellular senescence induced by cathepsin X downregulation
    Eur J Cell Biol (2011) 90, 678-686. PubMed  Europe PubMed DOI  K
  48. Paulick,M.G. and Bogyo,M.
    Development of activity-based probes for cathepsin X
    ACS Chem Biol (2011) 6, 563-572. PubMed  Europe PubMed DOI
  49. Ratovitski,T., Chighladze,E., Waldron,E., Hirschhorn,R.R. and Ross,C.A.
    Cysteine proteases bleomycin hydrolase and cathepsin Z mediate N-terminal proteolysis and toxicity of mutant huntingtin
    J Biol Chem (2011) 286, 12578-12589. PubMed  Europe PubMed DOI
  50. Wang,J., Chen,L., Li,Y. and Guan,X.Y.
    Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma
    PLoS ONE (2011) 6, e24967-e24967. PubMed  Europe PubMed DOI  PMC  EPMC
    51. 2010
  51. Bernhardt,A., Kuester,D., Roessner,A., Reinheckel,T. and Krueger,S.
    Cathepsin X-deficient gastric epithelial cells in co-culture with macrophages: characterization of cytokine response and migration capability after Helicobacter pylori infection
    J Biol Chem (2010) 285, 33691-33700. PubMed  Europe PubMed DOI  K
  52. Nagler,D.K., Kraus,S., Feierler,J., Mentele,R., Lottspeich,F., Jochum,M. and Faussner,A.
    A cysteine-type carboxypeptidase, cathepsin X, generates peptide receptor agonists
    Int Immunopharmacol (2010) 10, 134-139. PubMed  Europe PubMed DOI
  53. Sevenich,L., Schurigt,U., Sachse,K., Gajda,M., Werner,F., Muller,S., Vasiljeva,O., Schwinde,A., Klemm,N., Deussing,J., Peters,C. and Reinheckel,T.
    Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice
    Proc Natl Acad Sci U S A (2010) 107, 2497-2502. PubMed  Europe PubMed DOI  K
  54. Staudt,N.D., Aicher,W.K., Kalbacher,H., Stevanovic,S., Carmona,A.K., Bogyo,M. and Klein,G.
    Cathepsin X is secreted by human osteoblasts, digests CXCL-12 and impairs adhesion of hematopoietic stem and progenitor cells to osteoblasts
    Haematologica (2010) 95, 1452-1460. PubMed  Europe PubMed DOI
    55. 2009
  55. Fonovic,U.P. and Kos,J.
    Efficient removal of cathepsin L from active cathepsin X using immunoprecipitation technique
    Acta Chim Slov (2009) 56, 985-988.
  56. Jevnikar,Z., Obermajer,N., Pecar-Fonovic,U., Karaoglanovic-Carmona,A. and Kos,J.
    Cathepsin X cleaves the beta2 cytoplasmic tail of LFA-1 inducing the intermediate affinity form of LFA-1 and alpha-actinin-1 binding
    Eur J Immunol (2009) 39, 3217-3227. PubMed  Europe PubMed DOI
  57. Kos,J., Jevnikar,Z. and Obermajer,N.
    The role of cathepsin X in cell signaling
    Cell Adh Migr (2009) 3, 164-166. PubMed  Europe PubMed DOI  PMC  EPMC
  58. Obermajer,N., Jevnikar,Z., Doljak,B., Sadaghiani,A.M., Bogyo,M. and Kos,J.
    Cathepsin X-mediated beta2 integrin activation results in nanotube outgrowth
    Cell Mol Life Sci (2009) 66, 1126-1134. PubMed  Europe PubMed DOI
  59. Obermajer,N., Doljak,B., Jamnik,P., Fonovic,U.P. and Kos,J.
    Cathepsin X cleaves the C-terminal dipeptide of alpha- and gamma-enolase and impairs survival and neuritogenesis of neuronal cells
    Int J Biochem Cell Biol (2009) 41, 1685-1696. PubMed  Europe PubMed DOI  P
  60. Obermajer,N., Magister,S., Kopitar,A.N., Tepes,B., Ihan,A. and Kos,J.
    Cathepsin X prevents an effective immune response against Helicobacter pylori infection
    Eur J Cell Biol (2009) 88, 461-471. PubMed  Europe PubMed DOI
    61. 2008
  61. Ahn,S.J., Kim,N.Y., Jeon,S.J., Sung,J.H., Je,J.E., Seo,J.S., Kim,M.S., Kim,J.K., Chung,J.K. and Lee,H.H.
    Molecular cloning, tissue distribution and enzymatic characterization of cathepsin X from olive flounder (Paralichthys olivaceus)
    Comp Biochem Physiol B Biochem Mol Biol (2008) 151, 203-212. PubMed  Europe PubMed DOI
  62. Cooke,G.S., Campbell,S.J., Bennett,S., Lienhardt,C., McAdam,K.P., Sirugo,G., Sow,O., Gustafson,P., Mwangulu,F., Van Helden,P., Fine,P., Hoal,E.G. and Hill,A.V.
    Mapping of a novel susceptibility locus suggests a role for MC3R and CTSZ in human tuberculosis
    Am J Respir Crit Care Med (2008) 178, 203-207. PubMed  Europe PubMed DOI  PMC  EPMC
  63. Jevnikar,Z., Obermajer,N., Bogyo,M. and Kos,J.
    The role of cathepsin X in the migration and invasiveness of T lymphocytes
    J Cell Sci (2008) 121, 2652-2661. PubMed  Europe PubMed DOI
  64. Kao,C.M. and Huang,F.L.
    Cloning and expression of carp cathepsin Z: possible involvement in yolk metabolism
    Comp Biochem Physiol B Biochem Mol Biol (2008) 149, 541-551. PubMed  Europe PubMed DOI
  65. Obermajer,N., Svajger,U., Bogyo,M., Jeras,M. and Kos,J.
    Maturation of dendritic cells depends on proteolytic cleavage by cathepsin X
    J Leukoc Biol (2008) 84, 1306-1315. PubMed  Europe PubMed DOI
  66. Obermajer,N., Repnik,U., Jevnikar,Z., Turk,B., Kreft,M. and Kos,J.
    Cysteine protease cathepsin X modulates immune response via activation of beta2 integrins
    Immunology (2008) 124, 76-88. PubMed  Europe PubMed DOI  PMC  EPMC
    67. 2006
  67. Lechner,A.M., Assfalg-Machleidt,I., Zahler,S., Stoeckelhuber,M., Machleidt,W., Jochum,M. and Nagler,D.K.
    RGD-dependent binding of procathepsin X to integrin alpha vbeta 3 mediates cell-adhesive properties
    J Biol Chem (2006) 281, 39588-39597. PubMed  Europe PubMed DOI
  68. [YEAR:9-12-2006]Nagler,D.K., Lechner,A.M., Oettl,A., Kozaczynska,K., Scheuber,H.P., Gippner-Steppert,C., Bogner,V., Biberthaler,P. and Jochum,M.
    An enzyme-linked immunosorbent assay for human cathepsin X, a potential new inflammatory marker
    J Immunol Methods (9-12-2006) 308, 241-250. PubMed  Europe PubMed DOI  A
  69. [YEAR:11-5-2006]Obermajer,N., Premzl,A., Zavasnik Bergant,T., Turk,B. and Kos,J.
    Carboxypeptidase cathepsin X mediates beta2-integrin-dependent adhesion of differentiated U-937 cells
    Exp Cell Res (11-5-2006) 312, 2515-2527. PubMed  Europe PubMed DOI
    70. 2005
  70. [YEAR:5-1-2005]Appenzeller-Herzog,C., Nyfeler,B., Burkhard,P., Santamaria,I., Lopez-Otin,C. and Hauri,H.P.
    Carbohydrate- and conformation-dependent cargo capture for ER-Exit
    Mol Biol Cell (5-1-2005) 16, 1258-1267. PubMed  Europe PubMed DOI  PMC  EPMC
  71. [YEAR:8-4-2005]Devanathan,G., Turnbull,J.L., Ziomek,E., Purisima,E.O., Menard,R. and Sulea,T.
    Carboxy-monopeptidase substrate specificity of human cathepsin X
    Biochem Biophys Res Commun (8-4-2005) 329, 445-452. PubMed  Europe PubMed DOI  P
  72. [YEAR:15-7-2005]Krueger,S., Kalinski,T., Hundertmark,T., Wex,T., Kuster,D., Peitz,U., Ebert,M., Nagler,D.K., Kellner,U., Malfertheiner,P., Naumann,M., Rocken,C. and Roessner,A.
    Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer
    J Pathol (15-7-2005) 207, 32-42. PubMed  Europe PubMed DOI
  73. [YEAR:15-4-2005]Nascimento,F.D., Rizzi,C.C., Nantes,I.L., Stefe,I., Turk,B., Carmona,A.K., Nader,H.B., Juliano,L. and Tersariol,I.L.
    Cathepsin X binds to cell surface heparan sulfate proteoglycans
    Arch Biochem Biophys (15-4-2005) 436, 323-332. PubMed  Europe PubMed DOI
  74. Puzer,L., Cotrin,S.S., Cezari,M.H., Hirata,I.Y., Juliano,M.A., Stefe,I., Turk,D., Turk,B., Juliano,L. and Carmona,A.K.
    Recombinant human cathepsin X is a carboxymonopeptidase only: a comparison with cathepsins B and L
    Biol Chem (2005) 386, 1191-1195. PubMed  Europe PubMed DOI
    75. 2004
  75. Lustigman,S., Zhang,J., Liu,J., Oksov,Y. and Hashmi,S.
    RNA interference targeting cathepsin L and Z-like cysteine proteases of Onchocerca volvulus confirmed their essential function during L3 molting
    Mol Biochem Parasitol (2004) 138, 165-170. PubMed  Europe PubMed DOI
  76. Menard,R. and Sulea,T.
    Cathepsin X
    [ISSN:0-12-079610-4] (2004) 2, 1113-1116.  V
  77. [YEAR:1-7-2004]Nagler,D.K., Kruger,S., Kellner,A., Ziomek,E., Menard,R., Buhtz,P., Krams,M., Roessner,A. and Kellner,U.
    Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia
    Prostate (1-7-2004) 60, 109-119. PubMed  Europe PubMed DOI
    78. 2003
  78. Kelley,G.O., Adkison,M.A., Leutenegger,C.M. and Hedrick,R.P.
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