PHF type tau filament from R406W mutant
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 9eog
Q-score: 0.573
Qi C, Lovestam S, Murzin AG, Peak-Chew S, Franco C, Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ DOI: doi:10.1101/2024.04.29.591661 Pubmed: 38746388 ]
- Phf tau filament from mutant r406w (Complex from Homo sapiens)
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
PHF type tau filament from in vitro V337M mutant
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 9eoh
Q-score: 0.572
Qi C, Lovestam S, Murzin AG, Peak-Chew S, Franco C, Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ DOI: doi:10.1101/2024.04.29.591661 Pubmed: 38746388 ]
CTE type I tau filament from vacuolar tauopathy
Resolution: 2.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 9erm
Q-score: 0.68
Qi C, Kobayashi R, Kawakatsu S, Kametani F, Scheres SHW, Goedert M, Hasegawa M
Acta Neuropathol (2024) 147 pp. 86-86 [ Pubmed: 38758288 DOI: doi:10.1007/s00401-024-02741-x ]
CTE type II tau filament from vacuolar tauopathy
Resolution: 2.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 9ern
Q-score: 0.619
Qi C, Kobayashi R, Kawakatsu S, Kametani F, Scheres SHW, Goedert M, Hasegawa M
Acta Neuropathol (2024) 147 pp. 86-86 [ Pubmed: 38758288 DOI: doi:10.1007/s00401-024-02741-x ]
CTE type II tau filament from vacuolar tauopathy
Resolution: 2.9 Å
EM Method: Helical reconstruction
Fitted PDBs: 9ero
Q-score: 0.559
Qi C, Kobayashi R, Kawakatsu S, Kametani F, Scheres SHW, Goedert M, Hasegawa M
Acta Neuropathol (2024) 147 pp. 86-86 [ Pubmed: 38758288 DOI: doi:10.1007/s00401-024-02741-x ]
CTE typeI tau filament from Guam ALS/PDC
Resolution: 2.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ot6
Q-score: 0.709
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Tau filaments from guam als/pdc (Complex from Homo sapiens)
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
CTE typeIII tau filament from Guam ALS/PDC
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ot9
Q-score: 0.551
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Tau filaments from guam als/pdc (Complex from Homo sapiens)
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
CTE typeII tau filament from Guam ALS/PDC
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8otc
Q-score: 0.481
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Tau filaments from guam als/pdc (Complex from Homo sapiens)
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
TMEM106B Fold1-s filament from Guam ALS/PDC
Resolution: 2.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 8otd
Q-score: 0.61
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Tau filaments from guam als/pdc (Complex from Homo sapiens)
- Transmembrane protein 106b (31 kDa, Protein from Homo sapiens)
TMEM106B Fold I-d filament from Guam ALS/PDC
Resolution: 3.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ote
Q-score: 0.474
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Transmembrane protein 106b (31 kDa, Protein from Homo sapiens)
- Tmem106b fold1-d filaments from guam als/pdc (Complex from Homo sapiens)