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EMD-17175
TMEM106B Fold1-s filament from Guam ALS/PDC
EMD-17175
Helical reconstruction2.6 Å
Deposition: 20/04/2023Map released: 27/03/2024
Last modified: 09/10/2024
Sample Organism:
Homo sapiens
Sample: tau filaments from Guam ALS/PDC
Fitted models: 8otd
Deposition Authors: Qi C
,
Yang S,
Scheres SHW ,
Goedert M
Sample: tau filaments from Guam ALS/PDC
Fitted models: 8otd
Deposition Authors: Qi C
,
Yang S,
Scheres SHW ,
Goedert M
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Qi C ,
Verheijen BM,
Kokubo Y ,
Shi Y,
Tetter S,
Murzin AG,
Nakahara A ,
Morimoto S ,
Vermulst M,
Sasaki R ,
Aronica E,
Hirokawa Y ,
Oyanagi K ,
Kakita A ,
Ryskeldi-Falcon B,
Yoshida M,
Hasegawa M,
Scheres SHW ,
Goedert M
(2023) PNAS , 120 , e2306767120 - e2306767120
,
Verheijen BM,
Kokubo Y ,
Shi Y,
Tetter S,
Murzin AG,
Nakahara A ,
Morimoto S ,
Vermulst M,
Sasaki R ,
Aronica E,
Hirokawa Y ,
Oyanagi K ,
Kakita A ,
Ryskeldi-Falcon B,
Yoshida M,
Hasegawa M,
Scheres SHW ,
Goedert M
(2023) PNAS , 120 , e2306767120 - e2306767120
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_UP_A025_1013 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MC_U105184291 (United Kingdom)